Heritability and genomics of gene expression in peripheral blood

Wright, Fred A, Sullivan, Patrick F, Brooks, Andrew I, Zou, Fei, Sun, Wei, Xia, Kai, Madar, Vered, Jansen, Rick +31 more·2014·Nature Genetics

Cited by (364)

Items 101–200 of 364

  1. Imputing Gene Expression in Uncollected Tissues Within and Beyond GTEx
    Jiebiao Wang, Eric R. Gamazon, Brandon L. Pierce, Barbara E. Stranger, Hae Kyung Im, Robert David Gibbons, Nancy Jean Cox, Dan L. Nicolae, Lin Chen · 2016 · The American Journal of Human Genetics
  2. Simultaneous quantification of mRNA and protein in single cells reveals post-transcriptional effects of genetic variation
    Christian Brion, Sheila Lutz, Frank Wolfgang Albert · 2020 · eLife
  3. Subcutaneous and intramuscular fat transcriptomes show large differences in network organization and associations with adipose traits in pigs
    Yifeng Zhang, Yingchun Sun, Zhongzi Wu, Xinwei Xiong, Junjie Zhang, Junwu Ma, Shijun Xiao, Lusheng Huang, Bin Juan Yang · 2021 · Science China Life Sciences
  4. Integration of genomics and transcriptomics predicts diabetic retinopathy susceptibility genes
    Andrew D. Skol, Segun C. Jung, Ana Marija Sokovic, Siquan Chen, Sarah Fazal, Olukayode Ayodeji Sosina, Poulami P Borkar, Amy Lin, Maria S. Sverdlov, Dingcai Cao et al. · 2020 · eLife
  5. Generalised Anxiety Disorder – A Twin Study of Genetic Architecture, Genome-Wide Association and Differential Gene Expression
    Matthew N. Davies, Serena Verdi, Andrea Virginia Burri, Maciej Trzaskowski, Minyoung Lee, John M. Hettema, Rick Jansen, Dorret Irene Boomsma, Tim D. Spector · 2015 · PLoS ONE
  6. Enhanced understanding of the host–pathogen interaction in sepsis: new opportunities for omic approaches
    Cyndi Goh, Julian Charles Knight · 2017 · The Lancet Respiratory Medicine
  7. Genetic and environmental perturbations lead to regulatory decoherence
    Amanda J. Lea, Meena Subramaniam, Arthur Ko, Terho J. Lehtimäki, Emma Raitoharju, Mika A. P. Kähönen, Ilkka Seppälä, Nina Mononen, Olli Tuomas Raitakari, Mika Ala‐Korpela et al. · 2019 · eLife
  8. An empirical Bayes approach for multiple tissue eQTL analysis
    Gen Li, Andrey A. Shabalin, Ivan Rusyn, Fred A. Wright, Andrew B. Nobel · 2017 · Biostatistics
  9. Prediction of Alzheimer’s Disease-Associated Genes by Integration of GWAS Summary Data and Expression Data
    Sicheng Hao, Rui Wang, Yu Zhang, Hui Zhan · 2019 · Frontiers in Genetics
  10. Integrative genomics analysis reveals a 21q22.11 locus contributing risk to COVID-19
    Yunlong Ma, Yukuan Huang, Sen Zhao, Yinghao Yao, Yaru Zhang, Jia Qu, Nan Wu, Jianzhong Su · 2021 · Human Molecular Genetics
  11. Tissue-specific impact of FADS cluster variants on FADS1 and FADS2 gene expression
    Lindsay M. Reynolds, Timothy D. Howard, Ingo Ruczinski, Kanika Kanchan, Michael C. Seeds, Rasika A. Mathias, Floyd H. Chilton · 2018 · PLoS ONE
  12. Integrated Analysis of Summary Statistics to Identify Pleiotropic Genes and Pathways for the Comorbidity of Schizophrenia and Cardiometabolic Disease
    Hao Liu, Yang Sun, Xinxin Zhang, Shiyang Li, Dong Hu, Lei Xiao, Yanghui Chen, Lin He, Dao Wen Wang · 2020 · Frontiers in Psychiatry
  13. On Negative Heritability and Negative Estimates of Heritability
    David Steinsaltz, Andy W. Dahl, Kenneth W. Wachter · 2020 · Genetics
  14. Genetic control of longissimus dorsi muscle gene expression variation and joint analysis with phenotypic quantitative trait loci in pigs
    Deborah Velez‐Irizarry, S. Casiró, Kaitlyn R. Daza, Ronald O Bates, Nancy E. Raney, Juan Pedro Steibel, Catherine W. Ernst · 2019 · BMC Genomics
  15. BarkBase: Epigenomic Annotation of Canine Genomes
    Kate Megquier, Diane P. Genereux, Jessica Perry Hekman, Ross Swofford, Jason Turner-Maier, Jeremy Johnson, Jacob Alonso, Xue Li, Kathleen M. Morrill, Lynne J. Anguish et al. · 2019 · Genes
  16. DNA variants affecting the expression of numerous genes in trans have diverse mechanisms of action and evolutionary histories
    Sheila Lutz, Christian Brion, Margaret Kliebhan, Frank Wolfgang Albert · 2019 · PLoS Genetics
  17. The whole blood transcriptional regulation landscape in 465 COVID-19 infected samples from Japan COVID-19 Task Force
    Qing-Bo S. Wang, R. Edahiro, H. Namkoong, Takanori Hasegawa, Y. Shirai, K. Sonehara, Hiromu Tanaka, Ho Lee, R. Saiki, Takayoshi Hyugaji et al. · 2022 · Nature Communications
  18. Approaches for establishing the function of regulatory genetic variants involved in disease
    Julian Charles Knight · 2014 · Genome Medicine
  19. MRLocus: Identifying causal genes mediating a trait through Bayesian estimation of allelic heterogeneity
    Anqi Zhu, Nana Matoba, Emmaleigh Wilson, Amanda L. Tapia, Yun Li, Joseph G. Ibrahim, Jason L. Stein, Michael I. Love · 2021 · PLoS Genetics
  20. Circulating insulin-like growth factor I modulates mood and is a biomarker of vulnerability to stress: from mouse to man
    Andrea Santi, Mariska Bot, André Aleman, Brenda W.J.H. Penninx, I. Torres Aleman · 2018 · Translational Psychiatry
  21. A characterization of cis- and trans-heritability of RNA-Seq-based gene expression
    Klaasjan G. Ouwens, Rick Jansen, Michel Guillaume Nivard, Jenny van Dongen, Maia J. Frieser, Jouke‐Jan Hottenga, Wibowo Arindrarto, Annique Claringbould, Maarten van Iterson, Hailiang Mei et al. · 2019 · European Journal of Human Genetics
  22. Gene expression variability in human and chimpanzee populations share common determinants
    Benjamin Jung Fair, Lauren E. Blake, Abhishek Sarkar, Bryan J. Pavlovic, Claudia Cuevas, Yoav Gilad · 2020 · eLife
  23. How powerful are summary-based methods for identifying expression-trait associations under different genetic architectures?
    Yogasudha Veturi, Marylyn DeRiggi Ritchie · 2017 · Pacific Symposium on Biocomputing (PSB)
  24. A powerful fine-mapping method for transcriptome-wide association studies
    Chong Wu, W. Pan · 2019 · Human Genetics
  25. Genetic risk factors for endometriosis near estrogen receptor 1 and coexpression of genes in this region in endometrium
    Sushma Marla, Sally Mortlock, Sahar Houshdaran, Jenny N. Fung, Brett David McKinnon, Sarah J. Holdsworth‐Carson, Jane E. Girling, Peter A. W. Rogers, Linda C. Giudice, Grant W. Montgomery · 2020 · Molecular Human Reproduction
  26. Identification of expression quantitative trait loci associated with schizophrenia and affective disorders in normal brain tissue
    Oneil G. Bhalala, Artika P. Nath, Michael Inouye, Christopher R. Sibley · 2018 · PLoS Genetics
  27. A New Liver Expression Quantitative Trait Locus Map From 1,183 Individuals Provides Evidence for Novel Expression Quantitative Trait Loci of Drug Response, Metabolic, and Sex‐Biased Phenotypes
    Amy S. Etheridge, Paul J. Gallins, Dereje D. Jima, K. Alaine Broadaway, Mark J. Ratain, Erin G. Schuetz, Eric E. Schadt, Adrian Schröder, Cliona M. Molony, Yi‐Hui Zhou et al. · 2019 · Clinical Pharmacology & Therapeutics
  28. Inferring Causal Associations between Genes and Disease via the Mapping of Expression Quantitative Trait Loci
    Solveig K. Sieberts, Eric E. Schadt · 2019 · Wiley eBooks
  29. Attentional bias towards cannabis cues in cannabis users: A systematic review and meta-analysis
    Aisling O’Neill, Bianca Bachi, Sagnik Bhattacharyya · 2019 · Drug and Alcohol Dependence
  30. Establishing a Twin Register: An Invaluable Resource for (Behavior) Genetic, Epidemiological, Biomarker, and ‘Omics’ Studies
    Veronika V. Odintsova, Gonneke A. H. M. Willemsen, Conor V. Dolan, Jouke‐Jan Hottenga, Nicholas G. Martin, P. Eline Slagboom, Juan Ramón Ordoñana, Dorret Irene Boomsma · 2018 · Twin Research and Human Genetics
  31. The brain-derived neurotrophic factor pathway, life stress, and chronic multi-site musculoskeletal pain
    Ellen Generaal, Yuri Milaneschi, Rick Jansen, Bernet M. Elzinga, Joost Dekker, Brenda W.J.H. Penninx · 2016 · Molecular Pain
  32. RETRACTED: A computational approach to identify blood cell-expressed Parkinson's disease biomarkers that are coordinately expressed in brain tissue
    Mohammad Ali Moni, Humayan Kabir Rana, Md. Babul Islam, Mohammad Boshir Ahmed, Haoming Xu, Md. Al Mehedi Hasan, Yiming Lei, Julian M.W. Quinn · 2019 · Computers in Biology and Medicine · Retracted
  33. Molecular Systems Biology of Neurodevelopmental Disorders, Rett Syndrome as an Archetype
    Victor Faúndez, Meghan E. Wynne, Amanda J. Crocker, Daniel Charles Tarquinio · 2019 · Frontiers in Integrative Neuroscience
  34. Challenges and opportunities for the development of new antipsychotic drugs
    Carlos Forray, R. Buller · 2017 · Biochemical Pharmacology
  35. RNA sequencing of identical twins discordant for autism reveals blood-based signatures implicating immune and transcriptional dysregulation
    Ayden Saffari, Matthew J Arno, Erick E Nasser, Angelica Ronald, Chloe C. Y. Wong, Leonard C. Schalkwyk, Jonathan S. Mill, Frank Dudbridge, Emma L. Meaburn · 2019 · Molecular Autism
  36. Plasma Metabolomic Signatures of Chronic Obstructive Pulmonary Disease and the Impact of Genetic Variants on Phenotype-Driven Modules
    Lucas A. Gillenwater, Katherine Pratte, Brian D. Hobbs, Michael H. Cho, Yonghua Zhuang, Eitan Halper‐Stromberg, Charmion I. Cruickshank-Quinn, Nichole A. Reisdorph, Irina Petrache, Wassim W. Labaki et al. · 2020 · Network and Systems Medicine
  37. Gene Expression in Transformed Lymphocytes Reveals Variation in Endomembrane and HLA Pathways Modifying Cystic Fibrosis Pulmonary Phenotypes
    Wanda K. O’Neal, Paul J. Gallins, Rhonda G. Pace, Hong Dang, Whitney Wolf, Lisa C. Jones, XueLiang Guo, Yi‐Hui Zhou, Vered Madar, Jinyan Huang et al. · 2015 · The American Journal of Human Genetics
  38. Eye in a Disk: eyeIntegration Human Pan-Eye and Body Transcriptome Database Version 1.0
    Vinay S. Swamy, David M. McGaughey · 2019 · Investigative Ophthalmology & Visual Science
  39. Accurate and Fast Multiple-Testing Correction in eQTL Studies
    Jae Hoon Sul, Towfique Raj, Simone de Jong, Paul I. W. de Bakker, Soumya Raychaudhuri, Roel A. Ophoff, Barbara E. Stranger, Eleazar Eskin, Buhm Han · 2015 · The American Journal of Human Genetics
  40. Genome-wide association analysis identifies common variants influencing infant brain volumes
    Xia, K, Zhang, J, Ahn, M, Jha, S, Crowley, J J, Szatkiewicz, J, Li, T, Zou, F, Zhu, H, Hibar, D et al. · 2017 · Translational Psychiatry
  41. 2SNP heritability and effects of genetic variants for neutrophil-to-lymphocyte and platelet-to-lymphocyte ratio
    Bochao Danae Lin, Elena Carnero‐Montoro, Jordana T. Bell, Dorret Irene Boomsma, Eco J. C. de Geus, Rick Jansen, Cornelis Kluft, Massimo Mangino, Brenda W.J.H. Penninx, Tim D. Spector et al. · 2017 · Journal of Human Genetics
  42. Expression reflects population structure
    Brielin C. Brown, Nicolas Bray, Lior S. Pachter · 2018 · PLoS Genetics
  43. Pathogen-specific innate immune response patterns are distinctly affected by genetic diversity
    Antje Häder, Sascha Schäuble, Jan Gehlen, Nadja Thielemann, Benedikt C. Buerfent, Vitalia Schüller, Timo Hess, Thomas Wolf, Julia Schröder, Michael Weber et al. · 2023 · Nature Communications
  44. Deep-learning prediction of gene expression from personal genomes
    Shiron Drusinsky, Sean Whalen, Katherine S. Pollard · 2026 · Genome biology
  45. Fast and Accurate Construction of Confidence Intervals for Heritability
    Regev Schweiger, Shachar Kaufman, Reijo Laaksonen, Marcus Edi Kleber, Winfried März, Eleazar Eskin, Saharon Rosset, Eran Halperin · 2016 · The American Journal of Human Genetics
  46. Limits of Peripheral Blood Mononuclear Cells for Gene Expression-Based Biomarkers in Juvenile Idiopathic Arthritis
    Lai-Ping Wong, Kaiyu Jiang, Yanmin Chen, Teresa Hennon, Lucy Holmes, Carol A. Wallace, James N. Jarvis · 2016 · Scientific Reports
  47. In-Silico Analysis of Inflammatory Bowel Disease (IBD) GWAS Loci to Novel Connections
    Md Mesbah Uddin, Ramu Elango, Babajan Banaganapalli, Noor Ahmad Shaik, Fahad Ahmed Al-Abbasi · 2015 · PLoS ONE
  48. VRK2 gene expression in schizophrenia, bipolar disorder and healthy controls
    Martin Tesli, Katrine Verena Wirgenes, Timothy Hughes, Francesco Bettella, Lavinia Athanasiu, Eva Z. Hoseth, Mari Nerhus, Trine Vik Lagerberg, Nils Eiel Steen, Ingrid Agartz et al. · 2016 · The British Journal of Psychiatry
  49. An overview of posttraumatic stress disorder genetic studies by analyzing and integrating genetic data into genetic database PTSDgene
    Kunlin Zhang, Susu Qu, Suhua Chang, Gen Li, Chengqi Cao, Kechi Fang, Miranda Olff, Li Wang, Jing Wang · 2017 · Neuroscience & Biobehavioral Reviews
  50. Integrative genomics identifies new genes associated with severe COPD and emphysema
    Phuwanat Sakornsakolpat, Jarrett D. Morrow, Peter J. Castaldi, Craig P. Hersh, Yohan Bossé, Edwin K. Silverman, Ani W Manichaikul, Michael H. Cho · 2018 · Respiratory Research
  51. Ancestry-specific associations identified in genome-wide combined-phenotype study of red blood cell traits emphasize benefits of diversity in genomics
    C. Hodonsky, Antoine R. Baldassari, S. Bien, L. Raffield, H. Highland, C. Sitlani, G. Wojcik, R. Tao, M. Graff, Wei-Hong Tang et al. · 2020 · BMC Genomics
  52. In Silico Post Genome-Wide Association Studies Analysis of C-Reactive Protein Loci Suggests an Important Role for Interferons
    Ahmad Vaez, Rick Jansen, Bram Peter Prins, Jouke‐Jan Hottenga, Eco J. C. de Geus, Dorret Irene Boomsma, Brenda W.J.H. Penninx, Ilja Maria Nolte, Harold Snieder, Behrooz Z. Alizadeh · 2015 · Circulation Cardiovascular Genetics
  53. Genetic correlations reveal the shared genetic architecture of transcription in human peripheral blood
    Samuel W. Lukowski, Luke R. Lloyd‐Jones, Alexander Holloway, Holger Kirsten, Gibran Hemani, Jian Yang, Kerrin S. Small, Jing Zhao, Andres Metspalu, Emmanouil T. Dermitzakis et al. · 2017 · Nature Communications
  54. Incorporation of Biological Knowledge Into the Study of Gene-Environment Interactions
    Marylyn DeRiggi Ritchie, Joe R. Davis, Hugues Aschard, Alexis J. Battle, David V. Conti, Mengmeng Du, Eleazar Eskin, M. Daniele Fallin, Li Hsu, Peter L. Kraft et al. · 2017 · American Journal of Epidemiology
  55. Constraints on eQTL Fine Mapping in the Presence of Multisite Local Regulation of Gene Expression
    Biao Zeng, Luke R. Lloyd‐Jones, Alexander Holloway, Urko M. Marigorta, Andres Metspalu, Grant W. Montgomery, Tõnu Esko, Kenneth L. Brigham, Arshed Ali Quyyumi, Youssef Idaghdour et al. · 2017 · G3 Genes Genomes Genetics
  56. Longitudinal weight differences, gene expression and blood biomarkers in BMI-discordant identical twins
    Jenny van Dongen, Gonneke A. H. M. Willemsen, Bastiaan T. Heijmans, Jacoline Neuteboom, Cornelis Kluft, Rick Jansen, Brenda W.J.H. Penninx, P. Eline Slagboom, Eco J. C. de Geus, Dorret Irene Boomsma · 2015 · International Journal of Obesity
  57. A trans-eQTL network regulates osteoclast multinucleation and bone mass
    Marie Pereira, Jeong‐Hun Ko, John G. Logan, Hayley Protheroe, Kee‐Beom Kim, Amelia L.M. Tan, Peter Ian Croucher, Kwon-Sik Park, Maxime Rotival, Enrico G. Petretto et al. · 2020 · eLife
  58. Pre-infection antiviral innate immunity contributes to sex differences in SARS-CoV-2 infection
    N. Sauerwald, Zijun Zhang, Irene Ramos, V. Nair, Alessandra Soares-Schanoski, Yong-Chao Ge, Wei-Guang Mao, H. Alshammary, A. Gonzalez-Reiche, A. van de Guchte et al. · 2022 · Cell Systems
  59. Integration of transcriptome-wide association study and messenger RNA expression profile to identify genes associated with osteoarthritis
    Xin Qi, Fangfang Yu, Yan Fei Wen, Ping Li, Bolun Cheng, Mei Ma, Shiqiang Cheng, Lu Zhang, C. Liang, Li Liu et al. · 2020 · Bone and Joint Research
  60. Imputed gene expression risk scores: a functionally informed component of polygenic risk
    Oliver Pain, Kylie P. Glanville, Saskia P. Hagenaars, Saskia Selzam, Anna Elisabeth Fürtjes, Jonathan R. I. Coleman, Kaili Rimfeld, Gerome D. Breen, Lasse Folkersen, Cathryn M. Lewis · 2021 · Human Molecular Genetics
  61. Integrative transcriptome-wide analysis of atopic dermatitis for drug repositioning
    Jaeseung Song, Daeun Kim, Sora Lee, Junghyun Jung, Jong Wha J. Joo, Wonhee Jang · 2022 · Communications Biology
  62. Ethanol treatment of lymphoblastoid cell lines from alcoholics and non-alcoholics causes many subtle changes in gene expression
    McClintick, Jeanette N., Brooks, Andrew I., Deng, Li, Liang, Li, Wang, Jen C., Kapoor, Manav, Xuei, Xiaoling, Foroud, Tatiana, Tischfield, Jay A., Edenberg, Howard J. · 2014 · Alcohol
  63. Genetic imputation of kidney transcriptome, proteome and multi-omics illuminates new blood pressure and hypertension targets
    Xiaoguang Xu, Chachrit Khunsriraksakul, James Eales, Sébastien Rubin, David Scannali, Sushant Saluja, David Talavera, Havell Markus, Lida Wang, Maciej Drzal et al. · 2024 · Nature Communications
  64. Genetic Basis of Blood-Based Traits and Their Relationship With Performance and Environment in Beef Cattle at Weaning
    Josué Chinchilla‐Vargas, Luke Kramer, John D. Tucker, Don S Hubbell, Jeremy G Powell, Toby D. Lester, Elizabeth A. Backes, K. S. Anschutz, Jared E. Decker, Kenneth J. Stalder et al. · 2020 · Frontiers in Genetics
  65. Impact of long-term exposure to PM2.5 on peripheral blood gene expression pathways involved in cell signaling and immune response
    Jelle J. Vlaanderen, Roel C.H. Vermeulen, Matthew Whitaker, Marc Chadeau‐Hyam, Jouke‐Jan Hottenga, Eco J. C. de Geus, Gonneke A. H. M. Willemsen, Brenda W.J.H. Penninx, Rick Jansen, Dorret Irene Boomsma · 2022 · Environment International
  66. Longitudinal multi-omics study reveals common etiology underlying association between plasma proteome and BMI trajectories in adolescent and young adult twins
    Gabin Drouard, Fiona A. Hagenbeek, Alyce M. Whipp, René Pool, Jouke‐Jan Hottenga, Rick Jansen, Nikki Hubers, Alexey М. Afonin, Gonneke A. H. M. Willemsen, Eco J. C. de Geus et al. · 2023 · BMC Medicine
  67. Expression Quantitative Trait Loci Information Improves Predictive Modeling of Disease Relevance of Non-Coding Genetic Variation
    Damien C. Croteau‐Chonka, Angela J. Rogers, Towfique Raj, Michael J. McGeachie, Weiliang Qiu, John P. Ziniti, Benjamin J. Stubbs, Liming Liang, Fernando D. Martínez, Robert C. Strunk et al. · 2015 · PLoS ONE
  68. Expression Quantitative Trait Loci in Equine Skeletal Muscle Reveals Heritable Variation in Metabolism and the Training Responsive Transcriptome
    Gabriella Farries, Kenneth R. Bryan, Charlotte L. McGivney, Paul McGettigan, Katie F. Gough, John Arthur Browne, David Evan MacHugh, Lisa Michelle Katz, Emmeline Wynne Hill · 2019 · Frontiers in Genetics
  69. Converging evidence does not support GIT1 as an ADHD risk gene
    M. Klein, M. van der Voet, Benjamin Harich, K. V. van Hulzen, A. M. H. Onnink, M. Hoogman, T. Guadalupe, M. Zwiers, Johanne M. Groothuismink, Alicia Verberkt et al. · 2015 · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
  70. Functional SNPs in the Human Autoimmunity-Associated Locus 17q12-21
    Alina S. Ustiugova, Kirill V. Korneev, Dmitry V. Kuprash, Marina A. Afanasyeva · 2019 · Genes
  71. Risk alleles of genes with monoallelic expression are enriched in gain-of-function variants and depleted in loss-of-function variants for neurodevelopmental disorders
    Virginia Savova, S.V. Vinogradova, Dimtry Pruss, Alexander A. Gimelbrant, Lauren A. Weiss · 2017 · Molecular Psychiatry
  72. Diverse environmental perturbations reveal the evolution and context-dependency of genetic effects on gene expression levels
    Amanda J. Lea, Julie Peng, Julien F. Ayroles · 2022 · Genome Research
  73. A trans‐omic Mendelian randomization study of parental lifespan uncovers novel aging biology and therapeutic candidates for chronic diseases
    Nicolas Perrot, William Pelletier, Jérôme Bourgault, Christian Couture, Zhonglin Li, Patricia L. Mitchell, Nooshin Ghodsian, Yohan Bossé, Sébastien Thériault, Patrick Mathieu et al. · 2021 · Aging Cell
  74. Gene Expression Imputation Across Multiple Tissue Types Provides Insight Into the Genetic Architecture of Frontotemporal Dementia and Its Clinical Subtypes
    Lianne Maria Reus, Bogdan Paşaniuc, Daniëlle Posthuma, Toni A. Boltz, Raffaele Ferrari, Dena G. Hernandez, Mike A. Nalls, Jonathan Daniel Rohrer, Adaikalavan Ramasamy, John B. Kwok et al. · 2021 · Biological Psychiatry
  75. Limited evidence for blood eQTLs in human sexual dimorphism
    Eleonora Porcu, Annique Claringbould, Antoine Weihs, Kaido Lepik, Tom G. Richardson, Uwe Völker, Federico Andrea Santoni, Alexander Teumer, Lude Franke, Alexandre Reymond et al. · 2022 · Genome Medicine
  76. A phenome-wide association study of tandem repeat variation in 168,554 individuals from the UK Biobank
    Celine A. Manigbas, Bharati Jadhav, Paras Garg, Mariya Shadrina, William Lee, Gabrielle Altman, Alejandro Martin-Trujillo, Andrew J. Sharp · 2024 · Nature Communications
  77. Integrative analysis of Dupuytren's disease identifies novel risk locus and reveals a shared genetic etiology with BMI
    Megan Major, Malika Kumar Freund, Kathryn S. Burch, Nicholas Mancuso, Michael Ng, Dominic Furniss, Bogdan Paşaniuc, Roel A. Ophoff · 2019 · Genetic Epidemiology
  78. Heritability and GWAS Studies for Monocyte–Lymphocyte Ratio
    Bochao Danae Lin, Gonneke A. H. M. Willemsen, Iryna O. Fedko, Rick Jansen, Brenda W.J.H. Penninx, Eco J. C. de Geus, Cornelis Kluft, Jouke‐Jan Hottenga, Dorret Irene Boomsma · 2017 · Twin Research and Human Genetics
  79. Chromosome contacts in activated T cells identify autoimmune disease candidate genes
    Oliver S. Burren, Arcadio Rubio García, Biola M. Javierre, Daniel B. Rainbow, Jonathan Cairns, Nicholas J Cooper, John J. Lambourne, Ellen C. Schofield, Xaquín Castro Dopico, Ricardo C. Ferreira et al. · 2017 · bioRxiv (Cold Spring Harbor Laboratory)
  80. An Integrative Transcriptome-Wide Analysis of Amyotrophic Lateral Sclerosis for the Identification of Potential Genetic Markers and Drug Candidates
    Sungmin Park, Daeun Kim, Jaeseung Song, Jong Wha J. Joo · 2021 · International Journal of Molecular Sciences
  81. Multiple epistatic DNA variants in a single gene affect gene expression in trans
    Sheila Lutz, Krisna Van Dyke, Matthew A Feraru, Frank Wolfgang Albert · 2021 · Genetics
  82. Transcriptome-wide association study revealed two novel genes associated with nonobstructive azoospermia in a Chinese population
    Tingting Jiang, Yuzhuo Wang, Meng Zhu, Yifeng Wang, Mingtao Huang, Guangfu Jin, Xuejiang Guo, Jiahao Sha, Juncheng Dai, Zhibin Hu · 2017 · Fertility and Sterility
  83. RL-SKAT: An Exact and Efficient Score Test for Heritability and Set Tests
    Regev Schweiger, Omer Weissbrod, Elior Rahmani, Martina Müller‐Nurasyid, Sonja Kunze, Christian Gieger, Mélanie Waldenberger, Saharon Rosset, Eran Halperin · 2017 · Genetics
  84. Longitudinal Relationships Between Parents’ and Children’s Behavior Need Not Implicate the Influence of Parental Behavior and May Reflect Genetics: Comment on Waldinger and Schulz (2016)
    James M. Sherlock, Brendan P. Zietsch · 2017 · Psychological Science
  85. An independent component analysis confounding factor correction framework for identifying broad impact expression quantitative trait loci
    Jin Hyun Ju, Sushila A. Shenoy, Ronald G. Crystal, Jason G. Mezey · 2017 · PLoS Computational Biology
  86. A genome-wide survey of copy number variations reveals an asymmetric evolution of duplicated genes in rice
    Fengli Zhao, Yuexing Wang, Jianshu Zheng, Yanling Wen, Minghao Qu, Shujing Kang, Shigang Wu, Xiaojuan Deng, Kai Hong, Sanfeng Li et al. · 2020 · BMC Biology
  87. The heritability and patterns of DNA methylation in normal human colorectum
    Amy Rowlatt, Gustavo A. Hernandez-Suarez, María Carolina Sanabria‐Salas, Martha Lucía Serrano, Konrad Rawlik, Eva Hernández‐Illán, Cristina Alenda, Adela Castillejo, José Luís Soto, Chris Haley et al. · 2016 · Human Molecular Genetics
  88. Characterizing the Relation Between Expression QTLs and Complex Traits: Exploring the Role of Tissue Specificity
    Hill Fung Ip, Rick Jansen, Abdel Abdellaoui, Meike Bartels, Dorret Irene Boomsma, Michel Guillaume Nivard · 2018 · Behavior Genetics
  89. Untargeted Metabolome- and Transcriptome-Wide Association Study Suggests Causal Genes Modulating Metabolite Concentrations in Urine
    Reyhan Sönmez Flitman, Bita Khalili, Zoltán Kutalik, Rico Rueedi, Anneke Brümmer, Sven Bergmann · 2021 · Journal of Proteome Research
  90. Genome-wide human brain eQTLs: In-depth analysis and insights using the UKBEC dataset
    Letitia M.F. Sng, Peter Campbell Thomson, Daniah Trabzuni · 2019 · Scientific Reports
  91. Integrating transcriptome-wide association study and mRNA expression profiling identifies novel genes associated with bone mineral density
    Mei Ma, Dageng Huang, Xue Liang, Lei Zhang, Shiqiang Cheng, Bolun Cheng, Xin Qi, Peng Li, Yanan Du, L. Liu et al. · 2019 · Osteoporosis International
  92. Integrative analysis of transcriptome-wide association study and gene expression profiling identifies candidate genes associated with stroke
    Jian Yang, Bin Yan, Yajuan Fan, Lihong Yang, Binbin Zhao, Xiaoyan He, Qingyan Ma, Wei Wang, Ling Bai, Feng Zhang et al. · 2019 · PeerJ
  93. An empirical Bayes approach for multiple tissue eQTL analysis
    Fred A. Wright, Ivan Rusyn, Andrey A. Shabalin, Andrew B. Nobel, Li, Gen · 2024 · Carolina Digital Repository (University of North Carolina at Chapel Hill)
  94. A fast and powerful eQTL weighted method to detect genes associated with complex trait using GWAS summary data
    Jianjun Zhang, Sicong Xie, Samantha Gonzales, Jianguo Liu, Xuexia Wang · 2020 · Genetic Epidemiology
  95. Transcriptome‐based identification of novel endotypes in adult atopic dermatitis
    Alain Lefèvre‐Utile, Mélissa Saichi, Péter Oláh, Marc Delord, Bernhard Homey, Vassili Soumelis · 2021 · Allergy
  96. Non-additive genetic components contribute significantly to population-wide gene expression variation
    Andreas Tsouris, Gauthier Brach, Joseph Schacherer, Jing Hou · 2023 · Cell Genomics
  97. Integrative analysis of transcriptome‐wide association study and mRNA expression profiles identifies candidate genes associated with autism spectrum disorders
    Huimei Huang, Shiqiang Cheng, Miao Ding, Yan Fei Wen, Mei Ma, Lu Zhang, Ping Li, Bolun Cheng, Xiao Liang, Li Liu et al. · 2018 · Autism Research
  98. Integrated Analysis of Gene Expression Differences in Twins Discordant for Disease and Binary Phenotypes
    Sivateja Tangirala, Chirag J. Patel · 2018 · Scientific Reports
  99. IGREX for quantifying the impact of genetically regulated expression on phenotypes
    Mingxuan Cai, Lin Chen, Jin Liu, Can Yang · 2020 · NAR Genomics and Bioinformatics
  100. Crossing Phenotype Heritability and Candidate Gene Expression in Grafted Black-Lipped Pearl Oyster Pinctada margaritifera, an Animal Chimera
    Carole Blay, Serge Planes, Chin‐Long Ky · 2018 · Journal of Heredity