Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson’s disease

International Parkinson's Disease Genomics Consortium (IPDGC), Nalls, Mike A, Parkinson's Study Group (PSG) Parkinson's Research: The Organized GENetics Initiative (PROGENI), 23andMe, GenePD, NeuroGenetics Research Consortium (NGRC), Hussman Institute of Human Genomics (HIHG), The Ashkenazi Jewish Dataset Investigator +51 more·2014·Nature Genetics

Cited by (1,004)

Items 501–600 of 1,004

  1. Entanglement of Genetics and Epigenetics in Parkinson’s Disease
    Hendrikus J. van Heesbeen, Marten P. Smidt · 2019 · Frontiers in Neuroscience
  2. Gut microbiome: An intermediary to neurotoxicity
    Joseph L. Dempsey, Mallory Little, Julia Yue Cui · 2019 · NeuroToxicology
  3. Fine‐Mapping of SNCA in Rapid Eye Movement Sleep Behavior Disorder and Overt Synucleinopathies
    Lynne Krohn, Richard Y. J. Wu, Karl Heilbron, Jennifer A. Ruskey, Sandra B. Laurent, Cornelis Blauwendraat, Armaghan Alam, Isabelle Arnulf, Michele T.M. Hu, Yves A Dauvilliers et al. · 2020 · Annals of Neurology
  4. Leucine Rich Repeat Kinase 2 and Innate Immunity
    Diba Ahmadi Rastegar, Nicolas L. Dzamko · 2020 · Frontiers in Neuroscience
  5. Transposable elements and their KZFP controllers are drivers of transcriptional innovation in the developing human brain
    Christopher J. Playfoot, Julien Duc, Shaoline Sheppard, Sagane Joye, Alexandre Coudray, Evarist Planet, Didier Trono · 2021 · Genome Research
  6. Transcriptomic profiling of Parkinson's disease brains reveals disease stage specific gene expression changes
    Chiara Cappelletti, Sandra Pilar Henriksen, Hanneke Geut, Annemieke J.M. Rozemüller, Wilma D. J. van de Berg, Lasse Pihlstrøm, Mathias Toft · 2023 · Acta Neuropathologica
  7. Understanding the GTPase Activity of LRRK2: Regulation, Function, and Neurotoxicity
    An Phu Tran Nguyen, Darren J. Moore · 2017 · Advances in neurobiology
  8. Editor’s Highlight: Base Excision Repair Variants and Pesticide Exposure Increase Parkinson’s Disease Risk
    Laurie H. Sanders, Kimberly C. Paul, Evan H. Howlett, Hakeem O. Lawal, Sridhar Boppana, Jeff M. Bronstein, Beate R. Ritz, J. Timothy Greenamyre · 2017 · Toxicological Sciences
  9. Back and to the Future: From Neurotoxin‐Induced to Human Parkinson's Disease Models
    Mikko Airavaara, Ilmari Parkkinen, Julia Konovalova, Katrina Albert, Piotr Chmielarz, Andrii Domanskyi · 2020 · Current Protocols in Neuroscience
  10. Assessing Digital Phenotyping to Enhance Genetic Studies of Human Diseases
    Christopher DeBoever, Yosuke Tanigawa, Matthew Aguirre, Gregory McInnes, Adam Lavertu, Manuel A. Rivas · 2020 · The American Journal of Human Genetics
  11. The genetic architecture of the human thalamus and its overlap with ten common brain disorders
    Torbjørn Elvsåshagen, Alexey A. Shadrin, Oleksandr Frei, Dennis van der Meer, Shahram Bahrami, Vinod Kumar, Olav Bjerkehagen Smeland, Lars Tjelta Westlye, Ole A. Andreassen, Tobias Kaufmann · 2021 · Nature Communications
  12. Unraveling Parkinson’s Disease Neurodegeneration: Does Aging Hold the Clues?
    Colin Coleman, Ian Martin · 2022 · Journal of Parkinson s Disease
  13. Translational molecular imaging and drug development in Parkinson’s disease
    Ahmed Haider, Nehal H. Elghazawy, Alyaa Dawoud, Cathérine Gebhard, Thomas Wichmann, Wolfgang Sippl, Marius Christian Hoener, Ernest Arenas, Steven H. Liang · 2023 · Molecular Neurodegeneration
  14. Fine mapping and resequencing of the PARK16 locus in Parkinson’s disease
    Lasse Pihlstrøm, Aina Haugen Rengmark, Kari Anne Bjørnarå, Nil Dizdar, Camilla Fardell, Lars Forsgren, Björn Holmberg, Jan Petter Larsen, Jan Linder, Hans Nissbrandt et al. · 2015 · Journal of Human Genetics
  15. Computational analysis of the LRRK2 interactome
    Claudia Manzoni, Paul Denny, Ruth C. Lovering, Patrick Alfryn Lewis · 2015 · PeerJ
  16. The GBA variant E326K is associated with Parkinson's disease and explains a genome-wide association signal
    Victoria Berge‐Seidl, Lasse Pihlstrøm, Jodi Maple‐Grødem, Lars Forsgren, Jan Linder, Jan Petter Larsen, Ole‐Bjørn Tysnes, Mathias Toft · 2017 · Neuroscience Letters
  17. From Genomics to Omics Landscapes of Parkinson's Disease: Revealing the Molecular Mechanisms
    Sara Redenšek, Vita Dolžan, Tanja Kunej · 2018 · OMICS A Journal of Integrative Biology
  18. Mendelian randomization study shows no causal relationship between circulating urate levels and Parkinson's disease
    Demis A. Kia, Alastair John Noyce, Jon White, Doug Speed, Aude Nicolas, IPDGC collaborators, Stephen Burgess, Debbie A. Lawlor, George Davey Smith, Andrew Singleton et al. · 2018 · Annals of Neurology
  19. A Proposed Roadmap for Parkinson’s Disease Proof of Concept Clinical Trials Investigating Compounds Targeting Alpha-Synuclein
    Kalpana Merchant, Jesse M. Cedarbaum, Patrik Brundin, Kuldip D. Dave, Jamie L. Eberling, Alberto Javier Espay, Samantha J. Hutten, Monica Javidnia, Johan Luthman, Walter Maetzler et al. · 2018 · Journal of Parkinson s Disease
  20. Deregulation of autophagy and vesicle trafficking in Parkinson’s disease
    Patricia Sheehan, Zhenyu Yue · 2018 · Neuroscience Letters
  21. Missing heritability in Parkinson’s disease: the emerging role of non-coding genetic variation
    Jochen Ohnmacht, Patrick May, Lasse Sinkkonen, Rejko Krüger · 2020 · Journal of Neural Transmission
  22. Common X‐Chromosome Variants Are Associated with Parkinson Disease Risk
    Yann Le Guen, Valerio Napolioni, Michaël E. Belloy, Eric Yu, Lynne Krohn, Jennifer A. Ruskey, Ziv Gan‐Or, Gabriel Kennedy, Sarah J. Eger, Michael D. Greicius · 2021 · Annals of Neurology
  23. Biosensor approaches on the diagnosis of neurodegenerative diseases: Sensing the past to the future
    Münteha Nur Sonuç Karaboğa, Mustafa Kemal Sezgintürk · 2021 · Journal of Pharmaceutical and Biomedical Analysis
  24. 17q21.31 sub-haplotypes underlying H1-associated risk for Parkinson’s disease are associated with LRRC37A/2 expression in astrocytes
    Kathryn R. Bowles, Derian A. Pugh, Yiyuan Liu, Tulsi Patel, Alan Edward Renton, Sara Bandrés‐Ciga, Ziv Gan‐Or, Peter Heutink, Ari Siitonen, Sarah E. Bertelsen et al. · 2022 · Molecular Neurodegeneration
  25. Plasma EGF and cognitive decline in Parkinson's disease and Alzheimer's disease
    Nicholas Lim, Christine R. Swanson, H.R.R. Cherng, Travis L. Unger, Sharon Xiangwen Xie, Daniel A. Weintraub, KENNETH L. MAREK, Matthew B. Stern, Andrew D. Siderowf, PARS Investigators et al. · 2016 · Annals of Clinical and Translational Neurology
  26. Strong association between glucocerebrosidase mutations and Parkinson's disease in Sweden
    Caroline Ran, Lovisa Brodin, Lars Forsgren, Marie Westerlund, Mehrafarin Ramezani, Sandra Gellhaar, Fengqing Xiang, Camilla Fardell, Hans Nissbrandt, Peter Söderkvist et al. · 2016 · Neurobiology of Aging
  27. Genetic risk factors for cognitive decline in Parkinson's disease: a review of the literature
    Erin Fagan, Lasse Pihlstrøm · 2017 · European Journal of Neurology
  28. The development of inhibitors of leucine‐rich repeat kinase 2 (LRRK2) as a therapeutic strategy for Parkinson's disease: the current state of play
    Sonia Azeggagh, Daniel C. Berwick · 2021 · British Journal of Pharmacology
  29. An immunohistochemical, enzymatic, and behavioral study of CD157/BST-1 as a neuroregulator
    Haruhiro Higashida, Mingkun Liang, Toru Yoshihara, Shirin Akther, Azam A. K. M. Fakhrul, Черепанов Станислав Михайлович, Tae‐Sik Nam, Uh‐Hyun Kim, Satoka Kasai, Tomoko Nishimura et al. · 2017 · BMC Neuroscience
  30. A monocyte gene expression signature in the early clinical course of Parkinson’s disease
    Johannes C. M. Schlachetzki, Iryna Prots, Jenhan Tao, Hyun Bae Chun, Kaoru Saijo, David Gosselin, Beate Winner, Christopher K. Glass, Jürgen Winkler · 2018 · Scientific Reports
  31. The role of Rab GTPases in the pathobiology of Parkinson’ disease
    Luis Bonet‐Ponce, Mark R Cookson · 2019 · Current Opinion in Cell Biology
  32. Vesicle trafficking and lipid metabolism in synucleinopathy
    Saranna Fanning, Dennis J. Selkoe, Ulf Dettmer · 2020 · Acta Neuropathologica
  33. Mapping the serum proteome to neurological diseases using whole genome sequencing
    Png, Grace, Barysenka, Andrei, Repetto, Linda, Navarro, Pau, Shen, Xia, Pietzner, Maik, Wheeler, Eleanor, Wareham, Nicholas J., Langenberg, Claudia, Tsafantakis, Emmanouil et al. · 2021 · Nature Communications
  34. Oxidative Modification and Its Implications for the Neurodegeneration of Parkinson’s Disease
    Junjun Zhao, Shuqing Yu, Yan Zheng, Hui Yang, Jianliang Zhang · 2016 · Molecular Neurobiology
  35. Enrichment of risk SNPs in regulatory regions implicate diverse tissues in Parkinson’s disease etiology
    Simon G. Coetzee, Steven E. Pierce, Patrik Brundin, Lena Brundin, Dennis J. Hazelett, Gerhard A. Coetzee · 2016 · Scientific Reports
  36. Ginkgolide B and bilobalide ameliorate neural cell apoptosis in α-synuclein aggregates
    Jun Hua, Nuo Yin, Beibei Yang, Ji Zhang, Jianhua Ding, Yi Fan, Gang Hu · 2017 · Biomedicine & Pharmacotherapy
  37. Plasma urate and risk of Parkinson's disease: A mendelian randomization study
    Camilla Jannie Kobylecki, Børge Grønne Nordestgaard, Shoaib Afzal · 2018 · Annals of Neurology
  38. Evolution of prodromal parkinsonian features in a cohort of GBA mutation-positive individuals: a 6-year longitudinal study
    Micol Avenali, Marco Toffoli, Stephen Mullin, Alisdair McNeill, Derralynn A. Hughes, Atul B Mehta, Fabio Blandini, Anthony H.V. Schapira · 2019 · Journal of Neurology Neurosurgery & Psychiatry
  39. The potential roles of deubiquitinating enzymes in brain diseases
    Key‐Hwan Lim, Jae‐Yeol Joo, Kwang‐Hyun Baek · 2020 · Ageing Research Reviews
  40. Parkinson's Disease Derived Exosomes Aggravate Neuropathology in SNCA * A53T Mice
    Yang Xin Rui Huang, Zongran Liu, Na Li, Chen Tian, Han Kwang Yang, Yanfei Huo, Yang Li, Jing Zhang, Zhenwei Yu · 2022 · Annals of Neurology
  41. From the baker to the bedside: yeast models of Parkinson's disease
    Regina Menezes, Sandra Tenreiro, Diana Macedo, Cláudia Nunes dos Santos, Tiago F. Outeiro · 2015 · Microbial Cell
  42. Genetic Variants in MicroRNAs and Their Binding Sites Are Associated with the Risk of Parkinson Disease
    Mohsen Ghanbari, Sirwan K.L. Darweesh, Hans W. J. de Looper, Marvin M. van Luijn, Albert Hofman D, M. Arfan Ikram, Oscar H. Franco, Stefan J. Erkeland, Abbas Dehghan · 2015 · Human Mutation
  43. LRRK2 inhibitors and their potential in the treatment of Parkinson’s disease: current perspectives
    Farzaneh Atashrazm, Nicolas L. Dzamko · 2016 · Clinical Pharmacology Advances and Applications
  44. Epigenetic Biomarkers for Parkinson’s Disease: From Diagnostics to Therapeutics
    Jennifer L. Jakubowski, Viviane Labrie · 2016 · Journal of Parkinson s Disease
  45. Brain micro-inflammation at specific vessels dysregulates organ-homeostasis via the activation of a new neural circuit
    Yasunobu Arima, Takuto Ohki, Naoki Nishikawa, Kotaro Higuchi, Mitsutoshi Ota, Yuki Tanaka, Junko Nio‐Kobayashi, Mohamed Elfeky, Ryota Sakai, Yuki Mori et al. · 2017 · eLife
  46. Can Biomarkers Help the Early Diagnosis of Parkinson’s Disease?
    Weidong Le, Jie Dong, Song Li, Amos D. Korczyn · 2017 · Neuroscience Bulletin
  47. Proteomic analysis reveals co-ordinated alterations in protein synthesis and degradation pathways in LRRK2 knockout mice
    Laura Pellegrini, David N. Hauser, Yan Li, Adamantios Mamais, Alexandra G. Beilina, Ravindran Kumaran, Andrea Wetzel, Jonathon Nixon‐Abell, George Heaton, Iakov N. Rudenko et al. · 2018 · Human Molecular Genetics
  48. The Current State-of-the Art of LRRK2-Based Biomarker Assay Development in Parkinson’s Disease
    Hardy J. Rideout, Marie‐Christine Chartier‐Harlin, Matthew J. Fell, Warren D. Hirst, Sarah Huntwork, Cheryl E. G. Leyns, Omar S. Mabrouk, Jean‐Marc Taymans · 2020 · Frontiers in Neuroscience
  49. Multimodal phenotypic axes of Parkinson’s disease
    Ross D. Markello, Golia Shafiei, Christina Tremblay, Ronald B. Postuma, Alain Dagher, Bratislav Mišić · 2021 · npj Parkinson s Disease
  50. Involvement of Mitochondria in Parkinson’s Disease
    Chi‐Jing Choong, Hideki Mochizuki · 2023 · International Journal of Molecular Sciences
  51. Identification of genetic modifiers of age-at-onset for familial Parkinson’s disease
    Erin M. Hill‐Burns, Owen A. Ross, William T. Wissemann, Alexandra I. Soto‐Ortolaza, Sepideh Zareparsi, Joanna S. Siuda, Timothy Lynch, Zbigniew K. Wszołek, Peter A. Silburn, George D. Mellick et al. · 2016 · Human Molecular Genetics
  52. Gene and Network Analysis of Common Variants Reveals Novel Associations in Multiple Complex Diseases
    Priyanka Nakka, Benjamin J. Raphael, Sohini Ramachandran · 2016 · Genetics
  53. Cutaneous malignant melanoma and Parkinson disease: Common pathways?
    Rivka Inzelberg, Shira Flash, Eitan Friedman, Esther Azizi · 2016 · Annals of Neurology
  54. High-Throughput Characterization of Blood Serum Proteomics of IBD Patients with Respect to Aging and Genetic Factors
    Antonio Di Narzo, Shannon Telesco, Carrie M. Brodmerkel, Carmen Argmann, Lauren A. Peters, Katherine Li, Brian A. Kidd, Joel T. Dudley, Judy H. Cho, Eric E. Schadt et al. · 2017 · PLoS Genetics
  55. MAPT Genetic Variation and Neuronal Maturity Alter Isoform Expression Affecting Axonal Transport in iPSC-Derived Dopamine Neurons
    Joel E. Beevers, Mang Ching Lai, Emma Collins, Heather Booth, Federico Zambon, Laura Parkkinen, Jane Vowles, Sally A. Cowley, Richard Wade‐Martins, Tara M. Caffrey · 2017 · Stem Cell Reports
  56. Properties of global‐ and local‐ancestry adjustments in genetic association tests in admixed populations
    Eden R. Martin, Ilker Tunc, Zhi Liu, Susan H. Slifer, Ashley Harris Beecham, Gary W. Beecham · 2017 · Genetic Epidemiology
  57. Regional expression of genes mediating trans-synaptic alpha-synuclein transfer predicts regional atrophy in Parkinson disease
    Benjamin S. Freeze, Diana M. Acosta, Sneha Pandya, Yize Zhao, Ashish Raj · 2018 · NeuroImage Clinical
  58. Deep learning in systems medicine
    Haiying Wang, Estelle Pujos‐Guillot, Blandine Comte, João Luís de Miranda, Vojtěch Spiwok, Ivan Chorbev, Filippo Castiglione, Paolo Tieri, Steven Watterson, Roisin McAllister et al. · 2020 · Briefings in Bioinformatics
  59. <scp>A</scp> cumulative genetic risk score predicts progression in <scp>P</scp> arkinson's disease
    Pihlstrøm, Lasse, Morset, Kristina Rebekka, Grimstad, Espen, Vitelli, Valeria, Toft, Mathias · 2016 · Movement Disorders
  60. New hopes for disease modification in Parkinson's Disease
    Werner H Poewe, Klaus Seppi, Kathrin Marini, Philipp Mahlknecht · 2020 · Neuropharmacology
  61. Long-Term Outcomes of Genetic Parkinson’s Disease
    Jan Olav Aasly · 2020 · Journal of Movement Disorders
  62. pH regulates potassium conductance and drives a constitutive proton current in human TMEM175
    Wang Zheng, Chen Shen, Longfei Wang, Shaun D. Rawson, Wen Jun Xie, Carl A. Nist-Lund, Jason Hongliu Wu, Zhangfei Shen, Shiyu Xia, Jeffrey R. Holt et al. · 2022 · Science Advances
  63. Altered neural cell junctions and ion-channels leading to disrupted neuron communication in Parkinson’s disease
    Choudhury, Saptamita Paul, Bano, Sarika, Sen, Srijon, Suchal, Kapil, Kumar, Saroj, Nikolajeff, Fredrik, Dey, Sanjay Kumar, Sharma, Vaibhav · 2022 · npj Parkinson's Disease
  64. The role of NURR1 in metabolic abnormalities of Parkinson’s disease
    Murad Al‐Nusaif, Yuting Yang, Song Li, Cheng Cheng, Weidong Le · 2022 · Molecular Neurodegeneration
  65. SCARB2 variants and glucocerebrosidase activity in Parkinson’s disease
    Roy N. Alcalay, Oren A Levy, Pavlina Wolf, Petra Oliva, Xiaokui Kate Zhang, Cheryl Waters, Stanley Fahn, Un Jung Kang, Christopher Liong, Blair Ford et al. · 2016 · npj Parkinson s Disease
  66. Activating Autophagy as a Therapeutic Strategy for Parkinson’s Disease
    Alan J. Fowler, Charbel Moussa · 2018 · CNS Drugs
  67. Brain-Wide Genome-Wide Association Study for Alzheimer's Disease via Joint Projection Learning and Sparse Regression Model
    Tao Zhou, Kim‐Han Thung, Mingxia Liu, Dinggang G. Shen · 2018 · IEEE Transactions on Biomedical Engineering
  68. Genetic analysis of N6-methyladenosine modification genes in Parkinson's disease
    Lixia Qin, Shishi Min, Shu Li, Hongxu Pan, Junfei Zhong, Jifeng Guo, Qiying Sun, Xinxiang Yan, Chao Chen, Beisha Tang et al. · 2020 · Neurobiology of Aging
  69. Mining genetic and transcriptomic data using machine learning approaches in Parkinson’s disease
    Chang Su, Jie Tong, Fei Wang · 2020 · npj Parkinson s Disease
  70. Targeted sequencing of Parkinson’s disease loci genes highlights SYT11, FGF20 and other associations
    Uladzislau Rudakou, Eric Yu, Lynne Krohn, Jennifer A. Ruskey, Farnaz Asayesh, Yves A Dauvilliers, Dan Spiegelman, Lior Greenbaum, Stanley Fahn, Cheryl Waters et al. · 2020 · Brain
  71. Parkinson-Associated SNCA Enhancer Variants Revealed by Open Chromatin in Mouse Dopamine Neurons
    Sarah A. McClymont, Paul W. Hook, Alexandra I. Soto, Xylena Reed, William Law, Samuel J. Kerans, Eric L. Waite, Nicole Briceno, Joseph F. Thole, Michael G. Heckman et al. · 2018 · The American Journal of Human Genetics
  72. Nicotinamide-N-methyltransferase controls behavior, neurodegeneration and lifespan by regulating neuronal autophagy
    Kathrin Schmeißer, J. Alex Parker · 2018 · PLoS Genetics
  73. Systems level analysis of sex-dependent gene expression changes in Parkinson’s disease
    Léon-Charles Tranchevent, Rashi Halder, Enrico Glaab · 2023 · npj Parkinson s Disease
  74. Parkinson’s Disease: Exploring Different Animal Model Systems
    Engila Khan, Ikramul Hasan, M. Emdadul Haque · 2023 · International Journal of Molecular Sciences
  75. GBA1 Variants and Parkinson’s Disease: Paving the Way for Targeted Therapy
    Young Eun Huh, Tatiana Usnich, Clemens R. Scherzer, Christine Klein, Sun Ju Chung · 2023 · Journal of Movement Disorders
  76. Genome-wide estimate of the heritability of Multiple System Atrophy
    Monica Federoff, T. Ryan Price, Anna Sailer, Sonja W. Scholz, Dena G. Hernandez, Aude Nicolas, Andrew Singleton, Mike A. Nalls, Henry Houlden · 2015 · Parkinsonism & Related Disorders
  77. The biomarkers of immune dysregulation and inflammation response in Parkinson disease
    Li Chen, Mingshu Mo, Guangning Li, Luan Cen, Lei Wei, Yousheng Xiao, Xiang Chen, Shaomin Li, Xinling Yang, Shaogang Qu et al. · 2016 · Translational Neurodegeneration
  78. Cellular functions of LRRK2 implicate vesicular trafficking pathways in Parkinson's disease
    Mark Cookson · 2016 · Biochemical Society Transactions
  79. A Comprehensive Analysis of the Association Between SNCA Polymorphisms and the Risk of Parkinson's Disease
    Yuan Zhang, Shu Li, Qiying Sun, Hongxu Pan, Jifeng Guo, Beisha Tang · 2018 · Frontiers in Molecular Neuroscience
  80. Association of GALC, ZNF184, IL1R2 and ELOVL7 With Parkinson’s Disease in Southern Chinese
    Gen Li, Shishuang Cui, Juanjuan Du, Jin Liu, Pingchen Zhang, Yang Fu, Yixi He, Haiyan Zhou, Jianfang Ma, Shengdi Chen · 2018 · Frontiers in Aging Neuroscience
  81. Role of Tau in Various Tauopathies, Treatment Approaches, and Emerging Role of Nanotechnology in Neurodegenerative Disorders
    Preetpal Kaur, Alisha Khera, Hema Kumari Alajangi, Akanksha Sharma, Pradeep K. Jaiswal, Gurpal Singh, Ravi Pratap Barnwal · 2022 · Molecular Neurobiology
  82. Deregulation of protein translation control, a potential game-changing hypothesis for Parkinson's disease pathogenesis
    Taymans, Jean-Marc, Nkiliza, Aurore, Chartier-Harlin, Marie-Christine · 2015 · Trends in Molecular Medicine
  83. PARK10 is a major locus for sporadic neuropathologically confirmed Parkinson disease
    Gary W. Beecham, Dennis W. Dickson, William K. Scott, Eden R. Martin, Gerard D. Schellenberg, Karen Nuytemans, Eric Berg Larson, Joseph D. Buxbaum, John Q. Trojanowski, Vivianna M. Van Deerlin et al. · 2015 · Neurology
  84. MDSGene: Closing Data Gaps in Genotype-Phenotype Correlations of Monogenic Parkinson’s Disease
    Christine Klein, Nobutaka Hattori, Connie Marras · 2018 · Journal of Parkinson s Disease
  85. Autophagy and LRRK2 in the Aging Brain
    Federica Albanese, Salvatore Novello, Michele Morari · 2019 · Frontiers in Neuroscience
  86. Splice-Switching Antisense Oligonucleotides Reduce LRRK2 Kinase Activity in Human LRRK2 Transgenic Mice
    Joanna A. Korecka, Ria Thomas, Anthony J. Hinrich, Alyssa Moskites, Zachary K. Macbain, Penelope J. Hallett, Ole Isacson A, Michelle L. Hastings · 2020 · Molecular Therapy — Nucleic Acids
  87. Effect of LRRK2 protein and activity on stimulated cytokines in human monocytes and macrophages
    Diba Ahmadi Rastegar, Laura P. Hughes, Gayathri Perera, Shikara Keshiya, Siying Zhong, Jianqun Gao, Glenda Margaret Halliday, Birgitt Schüle, Nicolas L. Dzamko · 2022 · npj Parkinson s Disease
  88. The Consequences of GBA Deficiency in the Autophagy–Lysosome System in Parkinson’s Disease Associated with GBA
    Eddie Pradas, Marta Martínez‐Vicente · 2023 · Cells
  89. Prediction of Parkinson’s Disease Using Machine Learning Methods
    Jiayu Zhang, Wenchao Zhou, Hongmei Yu, Tong Wang, Xiaqiong Wang, Long Liu, Yalu Wen · 2023 · Biomolecules
  90. Parkinson’s Disease Genetic Loci in Rapid Eye Movement Sleep Behavior Disorder
    Ziv Gan‐Or, Simon Girard, Anne Noreau, Claire S. Leblond, Jean‐François Gagnon, Isabelle Arnulf, Cathy Mirarchi, Yves A Dauvilliers, Alex Désautels, Thomas Mitterling et al. · 2015 · Journal of Molecular Neuroscience
  91. Cannabidiol and Cannabinoid Compounds as Potential Strategies for Treating Parkinson’s Disease and l-DOPA-Induced Dyskinesia
    Nilson Carlos Ferreira‐Junior, Maurício dos Santos Pereira, Francisco Silveira Guimarães, Elaine Del Bel · 2019 · Neurotoxicity Research
  92. Lysosomal K+ channel TMEM175 promotes apoptosis and aggravates symptoms of Parkinson's disease
    Lili Qu, Bingqian Lin, Wenping Zeng, Chunhong Fan, Haotian Wu, Yushu Ge, Qianqian Li, Canjun Li, Yanan Wei, Jing Xin et al. · 2022 · EMBO Reports
  93. Novel Insight into Functions of Transcription Factor EB (TFEB) in Alzheimer’s Disease and Parkinson’s Disease
    Jing Yang, Wei Zhang, Shugeng Zhang, Ashok Iyaswamy, Jichao Sun, Jigang Wang, Chuanbin Yang · 2023 · Aging and Disease
  94. Genetic Determinants of Parkinson's Disease: Can They Help to Stratify the Patients Based on the Underlying Molecular Defect?
    Sara Redenšek, Maja Trošt, Vita Dolžan · 2017 · Frontiers in Aging Neuroscience
  95. The unlikely partnership between LRRK 2 and α‐synuclein in Parkinson's disease
    Noémie Cresto, Camille Gardier, Francesco Gubinelli, Marie‐Claude Gaillard, Géraldine Liot, West Andrew B, Emmanuel Brouillet · 2018 · European Journal of Neuroscience
  96. Advances in the Research of Risk Factors and Prodromal Biomarkers of Parkinson’s Disease
    Fen Xie, Xiaoya Gao, Wanlin Yang, Zihan Chang, Xiaohua Yang, Xiaobo Wei, Zifeng Huang, Huifang Xie, Zhenyu Yue, Fengli Zhou et al. · 2018 · ACS Chemical Neuroscience
  97. BioSEAL
    Roman Kaplan, Leonid Yavits, Ran Ginosasr · 2020 · ACM International Systems and Storage Conference (SYSTOR)
  98. Abundant non-inclusion α-synuclein pathology in Lewy body-negative LRRK2-mutant cases
    Nanna Møller Jensen, Zagorka Vitic, Mia R. Antorini, Tobias Bruun Viftrup, Laura Parkkinen, Poul Henning Jensen · 2025 · Acta Neuropathologica
  99. Genetic variability in ABCB1, occupational pesticide exposure, and Parkinson’s disease
    Shilpa Narayan, Janet S. Sinsheimer, Kimberly C. Paul, Zeyan Liew, Myles Cockburn, Jeff M. Bronstein, Beate R. Ritz · 2015 · Environmental Research
  100. Genetics of early-onset Parkinson's disease in Finland: exome sequencing and genome-wide association study
    Ari Siitonen, Mike A. Nalls, Dena G. Hernandez, Jesse Raphael Gibbs, Jinhui Ding, Pauli Ylikotila, Connor W. Edsall, Andrew Singleton, Kari Majamaa · 2017 · Neurobiology of Aging