Broad H3K4me3 is associated with increased transcription elongation and enhancer activity at tumor-suppressor genes

Chen, Kaifu, Chen, Zhong, Wu, Dayong, Zhang, Lili, Lin, Xueqiu, Su, Jianzhong, Rodriguez, Benjamin, Xi, Yuanxin +5 more·2015·Nature Genetics

Cited by (387)

Items 101–200 of 387

  1. The G-Protein-Coupled Estrogen Receptor (GPER) Regulates Trimethylation of Histone H3 at Lysine 4 and Represses Migration and Proliferation of Ovarian Cancer Cells In Vitro
    Nan Han, Sabine Heublein, Udo Jeschke, Christina Kühn, Anna Hester, Bastian Czogalla, Sven� Mahner, Miriam Rottmann, Doris Cooper Mayr, Elisa Schmoeckel et al. · 2021 · Cells
  2. Reprogramming of bivalent chromatin states in NRAS mutant melanoma suggests PRC2 inhibition as a therapeutic strategy
    Christopher J. Terranova, Ming Tang, Mayinuer Maitituoheti, Ayush T. Raman, Archit K. Ghosh, Jonathan Schulz, Samirkumar B. Amin, Elias Orouji, Katarzyna J. Tomczak, Sharmistha Sarkar et al. · 2021 · Cell Reports
  3. H3K4 demethylase KDM5B regulates cancer cell identity and epigenetic plasticity
    Runsheng He, Besa Xhabija, Lijin K. Gopi, Jiji Thulaseedhara Kurup, Zhishan Xu, Zhe Liu, Benjamin L. Kidder · 2022 · Oncogene
  4. The establishment of CDK9/RNA PolII/H3K4me3/DNA methylation feedback promotes HOTAIR expression by RNA elongation enhancement in cancer
    Chi Hin Wong, Chi Han Li, JOANNA H.M. TONG, Duo Zheng, HE Qi-fang, Zhiyuan Luo, Ut Kei Lou, Jiatong Wang, Ka‐Fai To, Yangchao Chen · 2022 · Molecular Therapy
  5. The chromatin remodeling protein Lsh alters nucleosome occupancy at putative enhancers and modulates binding of lineage specific transcription factors
    Jian-Ke Ren, R. Finney, Kai Ni, Maggie Cam, K. Muegge · 2019 · Epigenetics
  6. Broad H3K4me3 domains: Maintaining cellular identity and their implication in super‐enhancer hijacking
    Daniel Kent, Letizia Marchetti, Aneta Mikulášová, Lisa Jane Russell, Daniel Rico · 2023 · BioEssays
  7. The logic of transcriptional regulator recruitment architecture at <i>cis</i>-regulatory modules controlling liver functions
    Dubois-Chevalier, Julie, Dubois, Vanessa, Dehondt, Hélène, Mazrooei, Parisa, Mazuy, Claire, Sérandour, Aurélien A., Gheeraert, Céline, Guillaume, Penderia, Baugé, Eric, Derudas, Bruno et al. · 2017 · Genome Research
  8. An explainable artificial intelligence approach for decoding the enhancer histone modifications code and identification of novel enhancers in Drosophila
    Jareth C. Wolfe, Liudmila A Mikheeva, Hani Hagras, Nicolae Radu Zabet · 2021 · Genome biology
  9. Multimodal epigenetic sequencing analysis (MESA) of cell-free DNA for non-invasive colorectal cancer detection
    Yumei Li, Jianfeng Xu, Chaorong Chen, Zhenhai Lu, Desen Wan, Diange Li, Jason Sheng Li, Allison J. Sorg, Curt C. Roberts, Shivani Mahajan et al. · 2024 · Genome Medicine
  10. Functional Roles of H3K4 Methylation in Transcriptional Regulation
    Haoming Yu, Bluma J. Lesch · 2024 · Molecular and Cellular Biology
  11. Frequent hypermethylation of orphan CpG islands with enhancer activity in cancer
    Min Gyun Bae, Jeong Yeon Kim, Jung Kyoon Choi · 2016 · BMC Medical Genomics
  12. SETD1B-mediated broad H3K4me3 controls proper temporal patterns of gene expression critical for spermatid development
    Zhen Lin, Bowen Rong, Ruitu Lyu, Yuxuan Zheng, Chen Yao, Junyi Yan, Meixia Wu, Xiaogang Gao, Fuchou Tang, Fei Lan et al. · 2025 · Cell Research
  13. H3K27me3-rich genomic regions can function as silencers to repress gene expression via chromatin interactions
    Yichao Cai, Ying Zhang, Yan Ping Loh, Jia Qi Tng, Mei Chee Lim, Zhendong Cao, Anandhkumar Raju, Erez Lieberman Aiden, Shang Li, Lakshmanan Manikandan et al. · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
  14. Dynamics of broad H3K4me3 domains uncover an epigenetic switch between cell identity and cancer-related genes
    Mohamed Belhocine, Mathieu Simonin, José David Abad Flores, Agata Cieślak, Iris Manosalva, Lydie C. Pradel, Charlotte L. Smith, Ève-Lyne Mathieu, Guillaume Charbonnier, Joost H.A. Martens et al. · 2021 · Genome Research
  15. Targeting complexes of super‑enhancers is a promising strategy for cancer therapy (Review)
    Chuqian Zheng, Min Liu, Hong Fan · 2020 · Oncology Letters
  16. Inhibiting an RBM39/MLL1 epigenomic regulatory complex with dominant-negative peptides disrupts cancer cell transcription and proliferation
    Pavan Kumar P, Yao Yu, Kaelan R. Sullivan, Henok Eyob, Julian Markovich Rozenberg, Alana L. Welm, Chad Daniel Huff, Anne Moon · 2021 · Cell Reports
  17. H3K4 trimethylation regulates cancer immunity: a promising therapeutic target in combination with immunotherapy
    Chu Xiao, Tao T. Fan, Yujia Zheng, He Tian, Ziqin Deng, Jingjing Liu, Chunxiang Li, Jié He · 2023 · Journal for ImmunoTherapy of Cancer
  18. Genome-wide analysis reveals a role for TDG in estrogen receptor-mediated enhancer RNA transcription and 3-dimensional reorganization
    Bart Kolendowski, Haider M. Hassan, Milica Krstic, Majdina Isovic, Gobi Thillainadesan, Ann F. Chambers, Alan B. Tuck, Joseph Torchia · 2018 · Epigenetics & Chromatin
  19. Chorioamnionitis exposure remodels the unique histone modification landscape of neonatal monocytes and alters the expression of immune pathway genes
    Jennifer Bermick, Katherine Ann Gallagher, Aaron D. denDekker, Steven L. Kunkel, Nicholas W. Lukacs, Matthew A Schaller · 2018 · FEBS Journal
  20. H3K9me3, H3K36me3, and H4K20me3 Expression Correlates with Patient Outcome in Esophageal Squamous Cell Carcinoma as Epigenetic Markers
    Menghan Zhou, Yi‐Ping Li, Shaofeng Lin, Yanping Chen, Yanyan Qian, Zhujiang Zhao, Hong Fan · 2019 · Digestive Diseases and Sciences
  21. Epigenetic Mechanisms Governing Female and Male Germline Development in Mammals
    Kenjiro Shirane, Matthew C. Lorincz · 2022 · Sexual Development
  22. Enhancer, epigenetics, and human disease
    Zhuojuan Luo, Chengqi Lin · 2016 · Current Opinion in Genetics & Development
  23. ChIP-seq in Studying Epigenetic Mechanisms of Disease and Promoting Precision Medicine: Progresses and Future Directions
    Huihuang Yan, Shulan Tian, Susan L. Slager, Zhifu Sun · 2016 · Epigenomics
  24. Coactivators and general transcription factors have two distinct dynamic populations dependent on transcription
    Nikolaos Vosnakis, Marc Koch, Elisabeth Scheer, Pascal Kessler, Yves Mély, Pascal Didier, Làszlò Tora · 2017 · The EMBO Journal
  25. Broad Chromatin Domains: An Important Facet of Genome Regulation
    Francesco Nicola Carelli, Garima Sharma, Julie Ahringer · 2017 · BioEssays
  26. The Genetics of Seborrheic Dermatitis: A Candidate Gene Approach and Pilot Genome-Wide Association Study
    Martijn G.H. Sanders, Luba Milena Pardo, André Gerardus Uitterlinden, Adrian M Smith, Rebecca S. Ginger, Tamar E. C. Nijsten · 2017 · Journal of Investigative Dermatology
  27. Genome-Wide Identification of Histone Modifications Involved in Placental Development in Pigs
    Kun Soo Han, Ruimin Ren, Jianhua Cao, Shuhong Zhao, Mei Yu · 2019 · Frontiers in Genetics
  28. Epigenomic translocation of H3K4me3 broad domains over oncogenes following hijacking of super-enhancers
    Aneta Mikulášová, Daniel Kent, Marco Trevisán-Herraz, Nefeli Karataraki, Kent T.M. Fung, Cody Ashby, Agata Cieślak, Shmuel Yaccoby, Frits van Rhee, Maurizio Zangari et al. · 2021 · Genome Research
  29. Crosstalk between chromatin structure, cohesin activity and transcription
    Douglas Maya‐Miles, Eloísa Andújar, Mónica Pérez-Alegre, Marina Murillo-Pineda, Marta Barrientos‐Moreno, Maria Jose Cabello-Lobato, Elena Gómez-Marín, Macarena Morillo‐Huesca, Félix Prado · 2019 · Epigenetics & Chromatin
  30. Distribution pattern of histone marks potentially determines their roles in transcription and RNA processing in rice
    Yongfeng Hu, Yan Lai, Xiangsong Chen, Dao‐Xiu Zhou, Yu Jing Zhao · 2020 · Journal of Plant Physiology
  31. RNF20 and RNF40 regulate vitamin D receptor-dependent signaling in inflammatory bowel disease
    Robyn Laura Kosinsky, Maria Zerche, Ana P. Kutschat, Asha Nair, Zhenqing Ye, Dominik Saul, Maximilian von Heesen, Jessica J. Friton, Ana Carolina Schwarzer, Nadia Paglilla et al. · 2021 · Cell Death and Differentiation
  32. The histone H2B ubiquitin ligase RNF40 is required for HER2-driven mammary tumorigenesis
    Florian Wegwitz, Evangelos Prokakis, Anastasija Pejkovska, Robyn Laura Kosinsky, Markus Glatzel, Klaus Pantel, Harriet Wikman, Steven A. Johnsen · 2020 · Cell Death and Disease
  33. Recent advances in the chromatin-based mechanism of FLOWERING LOCUS C repression through autonomous pathway genes
    Jinseul Kyung, Myeongjune Jeon, Ilha Lee · 2022 · Frontiers in Plant Science
  34. TAZ2 truncation confers overactivation of p300 and cellular vulnerability to HDAC inhibition
    Longxia Xu, Hongwen Xuan, Wei He, Liang N. Zhang, Mengying Huang, Kuai Li, Hong Wen, Han Xu, Xiaobing Shi · 2023 · Nature Communications
  35. Dietary Organic Zinc Supplementation Modifies the Oxidative Genes via RORγ and Epigenetic Regulations in the Ileum of Broiler Chickens Exposed to High-Temperature Stress
    Saber Y. Adam, Madesh Muniyappan, Hao Huang, Wael Ennab, Hao‐Yu Liu, Abdelkareem Abdall Ahmed, Ming‐an Sun, Tadelle Dessie, In Ho Kim, Yun Hu et al. · 2024 · Antioxidants
  36. Cancer systems immunology
    Nathan Edward Reticker-Flynn, Edgar G. Engleman · 2020 · eLife
  37. Histone methyltransferases MLL2 and SETD1A/B play distinct roles in H3K4me3 deposition during the transition from totipotency to pluripotency
    Jingjing Zhang, Qiao-Ran Sun, Liang Liu, Shichun Yang, Xia Zhang, Yi‐Liang Miao, Xin Liu · 2024 · The EMBO Journal
  38. Cell Specificity of Human Regulatory Annotations and Their Genetic Effects on Gene Expression
    Arushi Varshney, Hadley VanRenterghem, Peter Orchard, Alan P. Boyle, Michael L. Stitzel, Duygu Ucar, Stephen C.J. Parker · 2018 · Genetics
  39. H3K4me3 Histone ChIP-Seq Analysis Reveals Molecular Mechanisms Responsible for Neutrophil Dysfunction in HIV-Infected Individuals
    Paweł Piątek, Maciej Tarkowski, Magdalena Namiecińska, Agostino Riva, Marek Wieczorek, Sylwia Michlewska, Justyna Dulska, Małgorzata Domowicz, Małgorzata Kulińska - Michalska, Natalia Lewkowicz et al. · 2021 · Frontiers in Immunology
  40. Extensive Epigenetic Changes Accompany Terminal Differentiation of Mouse Hepatocytes After Birth
    Matthew V. Cannon, Genay O.W. Pilarowski, Xiuli Liu, David Serre · 2016 · G3 Genes Genomes Genetics
  41. Mutational analysis of uterine cervical cancer that survived multiple rounds of radiotherapy
    Endang Nuryadi, Yasushi Sasaki, Yoshihiko Hagiwara, Tiara Bunga Mayang Permata, Hiro Sato, Shuichiro Komatsu, Yuya Yoshimoto, Kazutoshi Murata, Ken Ando, Nobuteru Kubo et al. · 2018 · Oncotarget
  42. Broad genic repression domains signify enhanced silencing of oncogenes
    Dongyu Zhao, Lili Zhang, Min Zhang, Bo Xia, Jie Lv, Xinlei Gao, Guangyu Wang, Qingshu Meng, Yi Yang, Sen Lin Zhu et al. · 2020 · Nature Communications
  43. Human Cytomegalovirus Infection Elicits Global Changes in Host Transcription by RNA Polymerases I, II, and III
    Christopher B. Ball, Mrutyunjaya Parida, Ming Li, Benjamin M. Spector, Gustavo A. Suarez, Jeffery L. Meier, David H. Price · 2022 · Viruses
  44. Oncogenic enhancers prime quiescent metastatic cells to escape NK immune surveillance by eliciting transcriptional memory
    Daniela Michelatti, Sven Beyes, Chiara Bernardis, Maria Luce Negri, Leonardo Morelli, N. Bediaga, V. Poli, L. Fagnocchi, Sara Lago, Sarah D'Annunzio et al. · 2024 · Nature Communications
  45. EpiMogrify Models H3K4me3 Data to Identify Signaling Molecules that Improve Cell Fate Control and Maintenance
    Uma Sangumathi Kamaraj, Joseph Chen, Khairunnisa Katwadi, John F. Ouyang, Yu Sun, Yu Ming Lim, Xiaodong Liu, Lusy Handoko, Jose Maria Polo, Enrico G. Petretto et al. · 2020 · Cell Systems
  46. The key role of differential broad H3K4me3 and H3K4ac domains in breast cancer
    Camila L. Lopez, Mohammad T. Barnon, Tasnim H. Beacon, Gino Nardocci, James Davie · 2022 · Gene
  47. The H2B ubiquitin-protein ligase RNF40 is required for somatic cell reprogramming
    Wanhua Xie, Michaela Miehe, Sandra D. Laufer, Steven A. Johnsen · 2020 · Cell Death and Disease
  48. Loss of grand histone H3 lysine 27 trimethylation domains mediated transcriptional activation in esophageal squamous cell carcinoma
    Jian Yuan, Qi Jiang, Tongyang Gong, Dandan Fan, Ji Zhang, Fukun Chen, Xiaolin Zhu, Xinyu Wang, Yunbo Qiao, Hongyan Chen et al. · 2021 · npj Genomic Medicine
  49. Transcription recycling assays identify PAF1 as a driver for RNA Pol II recycling
    Zhong Chen, William Hankey, Yue Zhao, Jeff Groth, Furong Huang, Hongyan Wang, Alexandre Rosa Campos, Jiaoti Huang, Robert G. Roeder, Qianben Wang · 2021 · Nature Communications
  50. Profiling of H3K4me3 and H3K27me3 and Their Roles in Gene Subfunctionalization in Allotetraploid Cotton
    Aicen Zhang, Yangyang Wei, Yining Shi, Xiaojuan Deng, Jingjing Gao, Yilong Feng, Dongyang Zheng, Xuejiao Cheng, Zhaoguo Li, Tao Wang et al. · 2021 · Frontiers in Plant Science
  51. Integrating nutriepigenomics in Parkinson’s disease management: New promising strategy in the omics era
    Khairiah Razali, Khaled Algantri, Su Peng Loh, Shi-Hui Cheng, Wael M.Y. Mohamed · 2022 · IBRO Neuroscience Reports
  52. Functional crosstalk between the cohesin loader and chromatin remodelers
    Sofía Muñoz, Andrew W. Jones, Céline Bouchoux, Tegan Gilmore, Harshil Patel, Frank Uhlmann · 2022 · Nature Communications
  53. Chromatin profiling identifies transcriptional readthrough as a conserved mechanism for piRNA biogenesis in mosquitoes
    Jieqiong Qu, Valerie Betting, Ruben van Iterson, Florence M. Kwaschik, Ronald P. van Rij · 2023 · Cell Reports
  54. Phase separation of PML/RARα and BRD4 coassembled microspeckles governs transcriptional dysregulation in acute promyelocytic leukemia
    Yi Zhang, Jiacheng Lou, Yabin Liu, Peng Jin, Yun Tan, Huan Song, Wen Yi Jin, Dan Wang, Fangyi Dong, Shishuang Wu et al. · 2024 · Proceedings of the National Academy of Sciences
  55. Nuclear microRNA 9 mediates G-quadruplex formation and 3D genome organization during TGF-β-induced transcription
    Julio Cordero, Guruprasadh Swaminathan, Diana G. Rogel-Ayala, Karla Rubio, Adel Elsherbiny, Samina Mahmood, Witold Szymański, J. Graumann, Thomas Braun, Stefan Günther et al. · 2024 · Nature Communications
  56. Disruption of Broad Epigenetic Domains in PDAC Cells by HAT Inhibitors
    D. Gerrard, Joseph R. Boyd, G. Stein, Victor X. Jin, Seth E. Frietze · 2019 · Epigenomes
  57. Regulation of genomic output and (pluri)potency in regeneration
    Duncan, Elizabeth M., Sánchez Alvarado, Alejandro · 2019 · Annual Review of Genetics
  58. Epigenomic landscape of enhancer elements during Hydra head organizer formation
    Puli Chandramouli Reddy, Akhila Gungi, Suyog Ubhe, Sanjeev Galande · 2020 · Epigenetics & Chromatin
  59. Molecular and computational approaches to map regulatory elements in 3D chromatin structure
    Beoung Hun Lee, S. Rhie · 2021 · Epigenetics & Chromatin
  60. In utero exposure to chlordecone affects histone modifications and activates LINE-1 in cord blood
    Louis Legoff, Shereen Cynthia D’Cruz, Katia Bouchekhchoukha, Christine Monfort, Christian Jaulin, Luc Multigner, Fatima O. Smagulova · 2021 · Life Science Alliance
  61. RNAPII driven post-translational modifications of nucleosomal histones
    Wai Soon Chan, Amarjeet Kumar, Hidetoshi Kono · 2022 · Trends in Genetics
  62. Expanded Potential Stem Cells from Human Embryos Have an Open Chromatin Configuration with Enhanced Trophoblast Differentiation Ability
    Andy Chun Hang Chen, Yin Lau Lee, Hanzhang Ruan, Wen Ming Huang, Sze Wan Fong, Siyu Isaac Parker Tian, Kai Chuen Lee, Genie Minju Wu, Yongqi Tan, Timothy Chun Hin Wong et al. · 2023 · Advanced Science
  63. A Functional Role for the Epigenetic Regulator ING1 in Activity-induced Gene Expression in Primary Cortical Neurons
    Laura Jane Leighton, Qiongyi Zhao, Xiang Li, Chuan-Yang Dai, Paul Robert Marshall, Sha Liu, Yi Wang, Esmi Lau Zajaczkowski, Nitin Khandelwal, Arvind Kumar et al. · 2017 · Neuroscience
  64. Proteasome inhibition creates a chromatin landscape favorable to RNA Pol II processivity
    Harriet Karimi Kinyamu, Brian D. Bennett, Pierre R. Bushel, Trevor Archer · 2020 · Journal of Biological Chemistry
  65. Mechanisms of Histone Modifications
    Ludovica Vanzan, Athéna Sklias, Maria Bošković, Zdenko Herceg, Rabih Murr, David M. Suter · 2022 · Elsevier eBooks
  66. Mitochondrial control through nutritionally regulated global histone H3 lysine-4 demethylation
    Maria Soloveychik, Mengshu Xu, Olga Zaslaver, Kwanyin Lee, Ashrut Narula, River Jiang, Adam P. Rosebrock, Amy A. Caudy, Marc D. Meneghini · 2016 · Scientific Reports
  67. Extracellular vesicle expansion of PMIS‐miR‐210 expression inhibits colorectal tumour growth via apoptosis and an XIST/NME1 regulatory mechanism
    Steven L. Eliason, Liu Hong, Yan Y. Sweat, Camille Chalkley, Huojun Cao, Qi Liu, Hank Heng Qi, Hongwei Xu, Fenghuang Zhan, Brad A. Amendt · 2022 · Clinical and Translational Medicine
  68. TrxG Complex Catalytic and Non-catalytic Activity Play Distinct Roles in Pancreas Progenitor Specification and Differentiation
    Stephanie A. Campbell, Cassandra L. McDonald, Nicole A. J. Krentz, Francis C. Lynn, Brad G. Hoffman · 2019 · Cell Reports
  69. Broad domains of histone marks in the highly compact Paramecium macronuclear genome
    Franziska Drews, Abdulrahman Salhab, Sivarajan Karunanithi, Miriam Cheaib, Martin Jung, Marcel H. Schulz, Martin C. Simon · 2022 · Genome Research
  70. Establishment of chromatin architecture interplays with embryo hypertranscription
    Guang Yu, Kai Xu, Weikun Xia, Ke Zhang, Qianhua Xu, Lijia Li, Zili Lin, Ling Liu, Bofeng Liu, Zhenhai Du et al. · 2025 · Nature
  71. Histone H3K4me3 breadth in hypoxia reveals endometrial core functions and stress adaptation linked to endometriosis
    Kalle T. Rytkönen, Thomas Faux, Mehrad Mahmoudian, Taija Heinosalo, Mauris C. Nnamani, Antti H Perheentupa, Matti H. POUTANEN, Laura L. Elo, Günter P. Wagner · 2022 · iScience
  72. Thyroid Hormone–mediated Histone Modification Protects Cortical Neurons From the Toxic Effects of Hypoxic Injury
    Kiyomi Abe, Jianrong Li, Yan‐Yun Liu, Gregory A. Brent · 2022 · Journal of the Endocrine Society
  73. Loss of the Ash2l subunit of histone H3K4 methyltransferase complexes reduces chromatin accessibility at promoters
    Mirna Barsoum, Alexander T. Stenzel, Agnieszka Bochyńska, Chao‐Chung Kuo, Alexander Tsompanidis, Roksaneh Sayadi-Boroujeni, Philip Bussmann, Juliane Lüscher‐Firzlaff, Ivan G. Costa, Bernhard Lüscher · 2022 · Scientific Reports
  74. Isoforms of the TAL1 transcription factor have different roles in hematopoiesis and cell growth
    Aveksha Sharma, Shani Mistriel-Zerbib, Rauf Ahmad Najar, Eden Engal, Mercedes Bentata, Nadeen Taqatqa, Sara Dahan, Klil Cohen, Shiri Jaffe‐Herman, Ophir Geminder et al. · 2023 · PLoS Biology
  75. Genome-wide analysis of H3K36me3 and its regulations to cancer-related genes expression in human cell lines
    Lu-Qiang Zhang, Qian‐Zhong Li, Wen Yi Jin, Yongchun Zuo, Shuchun Guo · 2018 · Biosystems
  76. Methylation of histone H3 lysine 4 is required for maintenance of beta cell function in adult mice
    Ben Vanderkruk, Nina Maeshima, Daniel J. Pasula, Meilin An, Cassandra L. McDonald, Priya Suresh, Dan S. Luciani, Francis C. Lynn, Brad G. Hoffman · 2023 · Diabetologia
  77. Proteasome inhibition creates a chromatin landscape favorable to RNA Pol II processivity
    Harriet Karimi Kinyamu, Brian D. Bennett, Pierre R. Bushel, Trevor Archer · 2019 · Journal of Biological Chemistry
  78. Hypoxic regulation of hypoxia inducible factor 1 alpha via antisense transcription
    Nicholas L. Downes, Henri Niskanen, Vanesa Tomas Bosch, Mari Taipale, Mehvash Godiwala, Mari‐Anna Väänänen, Tiia A. Turunen, Einari Aavik, Nihay Laham-Karam, Seppo Ylä‐Herttuala et al. · 2023 · Journal of Biological Chemistry
  79. Atypical chromatin structure of immune-related genes expressed in chicken erythrocytes
    Sanzida Jahan, Tasnim H. Beacon, Wayne Wenzhong Xu, James Davie · 2019 · Biochemistry and Cell Biology
  80. Epigenomic links from metabolism—methionine and chromatin architecture
    Zhengtao Xiao, Jason W. Locasale · 2021 · Current Opinion in Chemical Biology
  81. ChromTime: modeling spatio-temporal dynamics of chromatin marks
    Petko P. Fiziev, Jason Ernst · 2018 · Genome biology
  82. To incise or not and where: SET-domain methyltransferases know
    Michelle N. Yancoskie, Corina Maritz, Patrick van Eijk, Simon Huw Reed, Hanspeter Naegeli · 2022 · Trends in Biochemical Sciences
  83. Efficient activation of hundreds of LTR12C elements reveals cis-regulatory function determined by distinct epigenetic mechanisms
    Hitoshi Ohtani, Minmin Liu, Gangning Liang, H. Josh Jang, Peter A. Jones · 2024 · Nucleic Acids Research
  84. Epigenetic Modulation of Estrogen Receptor Signaling in Ovarian Cancer
    Maciej Skrzypczak, Ewa Wolińska, Łukasz Adaszek, Olaf Ortmann, Oliver Treeck · 2024 · International Journal of Molecular Sciences
  85. Integrative epigenomic profiling reveal AP-1 is a key regulator in intrahepatic cholangiocarcinoma
    Ke He, Yuliang Feng, Sanqi An, Fei Liu, Guoan Xiang · 2021 · Genomics
  86. Disruption of enhancer-driven S100A14 expression promotes esophageal carcinogenesis
    Xukun Li, Fang Ding, Lühua Wang, Hongyan Chen, Zhihua Liu · 2022 · Cancer Letters
  87. Low RNA stability signifies strong expression regulatability of tumor suppressors
    Xinlei Gao, Yi Yang, Jie Lv, Yanqiang Li, Arulsamy Kulandaisamy, Sahana Suresh Babu, Ivone Bruno, Lili Zhang, Qi Cao, Kaifu Chen · 2023 · Nucleic Acids Research
  88. Histone Mark Profiling in Pediatric Astrocytomas Reveals Prognostic Significance of H3K9 Trimethylation and Histone Methyltransferase SUV39H1
    Αλεξία Κλώνου, Penelope A. Korkolopoulou, Antonios N. Gargalionis, Dimitrios S. Kanakoglou, Hector Katifelis, Maria Gazouli, Sarantis Chlamydas, Andreas Mitsios, Theodosis Κalamatianos, George Stranjalis et al. · 2021 · Neurotherapeutics
  89. Deciphering the regulatory landscape of enhancer RNAs in health and disease
    Qian Wang, Peter ten Dijke, Chuannan Fan · 2026 · Signal Transduction and Targeted Therapy
  90. CHD6 promotes broad nucleosome eviction for transcriptional activation in prostate cancer cells
    Dongyu Zhao, Min Zhang, Shaodong Huang, Qi Liu, Sen Lin Zhu, Yanqiang Li, Weihua Jiang, Dániel Kiss, Qi Cao, Lili Zhang et al. · 2022 · Nucleic Acids Research
  91. Mechanistic aspects of reversible methylation modifications of arginine and lysine of nuclear histones and their roles in human colon cancer
    Ankan Roy, Niharika Niharika, Subhajit Chakraborty, Jagdish Mishra, Suraj Pratap Singh, Samir Kumar Patra · 2023 · Progress in molecular biology and translational science
  92. Doxorubicin, a DNA intercalator, inhibits transcription elongation
    Mathew Tempel, Kari Green, Dhanvi Prajapati, Angela Duaqui, Mahboobeh Norouzi, Hedieh Sattarifard, Ahmed Bilal Ashraf, Elly Wu, Athanasios Zovoilis, Ted M. Lakowski et al. · 2025 · Biochemistry and Cell Biology
  93. Set1 Targets Genes with Essential Identity and Tumor-Suppressing Functions in Planarian Stem Cells
    Prince Verma, Courtney K. M. Waterbury, Elizabeth M. Duncan · 2021 · Genes
  94. Effects of Multi-Omics Characteristics on Identification of Driver Genes Using Machine Learning Algorithms
    Feng Li, Xin Chu, Ling-Yun Dai, Juan Wang, Jin‐Xing Liu, Junliang Shang · 2022 · Genes
  95. DNA Methylation of Intragenic CpG Islands are Required for Differentiation from iPSC to NPC
    Won‐Young Choi, Ji-Hyun Hwang, Ann‐Na Cho, Andrew Lee, Jung Woo Lee, Inkyung Jung, Seung‐Woo Cho, Lark Kyun Kim, Young-Joon Kim · 2020 · Stem Cell Reviews and Reports
  96. Broad H3K4me3 as A Novel Epigenetic Signature for Normal Development and Disease
    Jie Lv, Kaifu Chen · 2016 · Genomics Proteomics & Bioinformatics
  97. Diet-induced obesity induces oxidative stress and enhances H3K4me3 levels, driving nonresolving inflammation and myelopoiesis in hematopoietic stem and progenitor cells
    Kentaro Takahashi, Julia Drolet, Jinghua Liu, Jasmine R Jackson, Muthusamy Thiruppathi, Milie M. Fang, Jack Rogers, Ian D. Davis, Giamila Fantuzzi, Elizaveta V. Benevolenskaya et al. · 2025 · The Journal of Immunology
  98. Dynamic and distinct histone modifications facilitate human trophoblast lineage differentiation
    Bum‐Kyu Lee, Joudi Salamah, Elisha Ann Cheeran, Enoch Appiah Adu‐Gyamfi · 2024 · Scientific Reports
  99. Setd2 overexpression rescues bivalent gene expression during SCNT-mediated ZGA
    Xiaolei Zhang, Ruimin Xu, Yuyan Zhao, Yijia Yang, Qi Shi, Hong Wang, Xiaoyu Liu, Shaorong Gao, Chong V. Li · 2025 · Protein & Cell
  100. CREATE: cell-type-specific cis-regulatory element identification via discrete embedding
    Xuejian Cui, Qijin Yin, Zijing Gao, Zhen Li, Xiaoyang Chen, Hairong Lv, Shengquan Chen, Qiao Liu, Wanwen Zeng, Rui Jiang · 2025 · Nature Communications