Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia

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Items 401–479 of 479

1. Genotype Prediction of Adult Type 2 Diabetes From Adolescence in a Multiracial Population
   2012 · PEDIATRICS
2. Sleep Patterns and Academic Performance among Medicine and Pharm D students in Almaarefa University 2018-2019
   Mashel A. Alzunidi, Jawaher A Alowayyid, Rabab A Benhadi, Habiba H. Farouk, Malak H. Alshammari, Asmaa S. Sultan, Rana A. Almojil, Alanoud A. Alshathri, Noor N. Alsalman, Shahad S. Alshaya et al. · 2022 · World Family Medicine Journal/Middle East Journal of Family Medicine
3. Prevalence of overt and subclinical hypothyroidism during pregnancy in antenatal care - cross-sectional study, Jeddah, Saudi Arabia
   Lubna M. Zahrani, Mada I. Abdulhaq, Taghreed M. Shams, Fayssal Mostafa Farahat · 2022 · World Family Medicine Journal/Middle East Journal of Family Medicine
4. Improving T2D machine learning-based prediction accuracy with SNPs and younger age
   Cynthia Al Hageh, Andreas Henschel, Hao Zhou, Jorge Passamani Zubelli, Moni Nader, Stéphanie Chacar, Nantia D. Iakovidou, Haralampos Hatzikirou, Antoine Abchee, Siobhán O’Sullivan et al. · 2025 · Computational and Structural Biotechnology Journal
5. The Challenging Chase for Nutrigenetic Predictors of Metabolic Responses to Dietary Interventions
   Mark A. Sarzynski, Claude Bouchard · 2013 · Diabetes Care
6. Transcription Factor 7-Like 2 (TCF7L2)
   Struan F.A. Grant, Leif Groop · 2016 · Springer eBooks
7. Rethinking the design process, rethinking the curriculum
   Michele Corsi, Pier Giuseppe Rossi · 2018 · EDUCATION SCIENCES AND SOCIETY
8. Prevalence of Generalized Anxiety Disorder among Medical Residents in Hamad Medical Corporation in 2020
   Mohamed Abdullah Jummah Hnish, Nashwan Zainal Deen, Salma Snoussi, Hind Mohamad, Mohamed Abdalla, Issameldin Abdelbagi · 2022 · World Family Medicine Journal/Middle East Journal of Family Medicine
9. A bioinformatics approach to the identification of type 2 diabetes susceptibility gene variants in Africans
   Ovokeraye H. Oduaran · 2015 · University of the Witwatersrand, Johannesburg Institutional Repository on DSpace (University of the Witwatersrand, Johannesburg)
10. The association of DNA methylation patterns in TCF7L2 and GIPR genes with Type 2 Diabetes
    Sílvia Canivell · 2014 · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)
11. The genetics of type 2 diabetes
    Emma Ahlqvist, Leif Groop · 2015 · Wiley eBooks
12. eplication of genome wide association-validated loci for type 2 diabetes mellitus in the Saudi Arabian population
    Nasser M. Al‐Daghri, Khalid M. Alkharfy, Majed Saleh Alokail, Amal Majed H. Alenad, Omar Salem Al-Attas, Abdul Khader Mohammad, Shaun Sabico, Omar Albagha · 2013 · Endocrine Abstracts
13. The role of CADM1 in energy and glucose homeostasis
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14. The grey zone between type 1 and type 2 diabetes : genetic aspects of diabetes in adults
    Mette Korre Andersen · 2012 · Työväentutkimus Vuosikirja
15. Exploring the structure, function & regulation of the human glucagon-like peptide-1 receptor
    Yan Huang · 2011 · Figshare
16. Genetic Architecture And Clinical Outcomes Of The Fredrickson-Levy-Lees Dyslipoproteinemias
    Thomas Gilliland, Jacqueline S. Dron, Margaret Sunitha Selvaraj, Mark Trinder, Kaavya Paruchuri, Sarah Urbut, Sara Haidermota, Rachel C. Bernardo, Md Mesbah Uddin, Michael C. Honigberg et al. · 2022 · medRxiv
17. Association between cytomegalovirus infection and insulin resistance: evidence from the National Health and Nutrition Examination Survey (1999-2004)
    Hui Gao, Yang Yang, Fengqing Cai, Qian Wang, Xinyu He, Changxuan Sun, Hongqiang Shen, Guannan Bai · 2024 · Research Square
18. Heritability of type 2 diabetes and related traits
    Mikko Lehtovirta · 2014 · Työväentutkimus Vuosikirja
19. The effects of known type 2 diabetes susceptibility loci on complications of the disease
    Valborg Guðmundsdóttir · 2012
20. Recent Progress in Identifying Genes Contributing to Type 2 Diabetes and Metabolic Syndrome
    Weijia Xie, Timothy M. Frayling, Michael N. Weedon · 2011 · Wiley eBooks
21. Génétique du diabète de type 2. Découverte d’un polymorphisme associé à une insulinorésistance
    Jean‐Pierre Riveline · 2011 · Médecine des Maladies Métaboliques
22. Genome-wide association studies of Type 2 diabetes: are these ready to make an impact in the clinic?
    G Thanabalasingham, Anna L. Gloyn, Katharine R. Owen · 2011 · Diabetes Management
23. Novel type 2 diabetes mellitus risk locus near IRS1 is associated with insulin resistance and hyperinsulinemia
    Linda Koch · 2009 · Nature Reviews Endocrinology
24. Recent Developments in the Genetic and Genomic Basis of Type 2 Diabetes
    Hannah B. Richards, Mark I. McCarthy · 2012 · Current Cardiovascular Risk Reports
25. The use of Bayes factors in fine-scale genetic association studies
    Robin Young · 2011 · Enlighten: Theses (The University of Glasgow)
26. The susceptibility to metabolic and proliferative diseases - from genetic predisposition to treatment
    Cristina Maglio · 2014 · Gothenburg University Publications Electronic Archive (Gothenburg University)
27. BÚSQUEDA DE LA MUTACIÓN Phe-809 EN EL GEN DEL SUSTRATO DEL RECEPTOR DE INSULINA -1 (IRS-1) EN RATAS DIABÉTICAS eSS
    Stella Maris Daniele, Silvana Marisa Montenegro, María Cristina Tarrés, Stella Maris Martínez · 2010
28. Genome-Wide Association Studies of Glycaemic Traits: A MAGICal Journey
    José C. Florez, Inês Barroso · 2014 · Frontiers in diabetes
29. Genetic Pleiotropies of Obesity
    Bratati Kahali, Elizabeth K. Speliotes · 2013 · Springer eBooks
30. Polymorphism, Carbohydrates, Fat, and Type 2 Diabetes
    José López‐Miranda, Carmen Marı́n · 2016 · Elsevier eBooks
31. Characterization and Diurnal Measurement of Oral Inflammation in Association with Glycemic Control, Periodontal Status, & Glucose Stimulation
    Melanie N. Kuehl · 2015 · Digital Commons - University of South Florida (University of South Florida)
32. Genetic Defects in Human Pericentrin Are Associated With Severe Insulin Resistance and Diabetes
    Majewski Osteodysplastic · 2016
33. Genome-Wide Association Studies of Quantitative Glycaemic Traits
    Inês Barroso, Robert A. Scott · 2016 · Springer eBooks
34. La N-acétyltransférase 2 influence la sensibilité à l’insuline
    Stéphane Cauchi · 2016 · Médecine des Maladies Métaboliques
35. SNPs and Type 2 Diabetes
    Maria Poulasouchidou, Alexandros F. Lambropoulos · 2010 · Aristotle University Medical journal/Aristotle University Medical Journal
36. The Genetic Mechanisms Underlying Human Obesity
    Stephen J. Clark · 2012
37. Maternal Macronutrient Intakes, Glucose Metabolism during Pregnancy and Metabolic Hormones in Human Milk
    Sylvia H. Ley · 2012 · TSpace (University of Toronto)
38. Endoplasmic reticulum calcium dynamics and insulin secretion in pancreatic β cells
    Wataru R. Yamamoto · 2017 · IUScholarWorks (Indiana University)
39. Genetics of Diabetes and Diabetic Complications
    Rashmi B. Prasad, Emma Ahlqvist, Leif Groop · 2018 · Endocrinology
40. Cellular & Molecular Mechanisms That Contribute to the Early Development of Skeletal Muscle & Systemic Insulin Resistance
    Brian A. Grice · 2019 · IUScholarWorks (Indiana University)
41. DETERMINANTS OF FORMING CHARACTERISTICS OF A GROUP OF HYPERTENSIVE PATIENTS WITH VARIOUS BODY WEIGHT AND TYPE 2 DIABETES MELLITUS
    Valentyna Psarova · 2020 · Bulletin of Problems Biology and Medicine
42. Novel Gluconeogenesis Regulators for Anti-diabetic Drug Repurposing using Transgenic Zebrafish pck1 Reporters
    Ji Dong K. Bai · 2015 · TSpace (University of Toronto)
43. Insulin resistance and obesity
    A. A. Farooqui · 2020 · Elsevier eBooks
44. ГЕНЕТИКА ЦУКРОВОГО ДІАБЕТУ 2 ТИПУ ТА ЙОГО ПОЄДНАННЯ З ОЖИРІННЯМ І ХРОНІЧНИМ ПАНКРЕАТИТОМ
    Уляна Петрівна Гевко, М. І. Марущак · 2021 · Medical and Clinical Chemistry
45. Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene
    HJ Laakso, Mingang Hao, K Ingelsson, E Frayling · 2015
46. Association of Genetic Polymorphism of Insulin Receptor Substrate 1 (IRS-1) with Polycystic Ovary Syndrome Pathogenicity in Iraqi Women
    Zahraa Fouad Fadhil, Ban Hoshi Khalaf, Hassan Mahmood Mousa Abo Almaali · 2021 · Medico-Legal Update
47. Associação de variantes em MC3R, MC4R, IRS1 e IRS2 com obesidade e marcadores metabólicos, inflamatórios e adipocinas
    Cristina Moreno Fajardo · 2020 · Digital Library of Theses and Dissertations (Universidade de São Paulo)
48. Problem Solving Behavior of Teenagers: An Indicator for Classroom Management.
    Frederick J. Behrle · 1972
49. Current World Literature
    2010 · Current Opinion in Lipidology
50. Genetics of Obesity
    Alexis C. Wood, Zhe Wang · 2016 · Springer eBooks
51. Diabetic Ketoacidosis
    Paula Mayo, David Clarke · 2017
52. The Genetic Determinants of Common Obesity-Susceptibility
    Ruth J. F. Loos · 2017 · Springer eBooks
53. All thresholds of maternal hyperglycaemia from the WHO 2013 criteria for gestational diabetes identify women with a higher genetic risk for type 2 diabetes
    Alice E. Hughes, M. Geoffrey Hayes, Aoife Maria Egan, Kashyap Patel, Denise M. Scholtens, Lynn P. Lowe, William L. Lowe, Fidelma Dunne, Andrew Tym Hattersley, Rachel M. Freathy · 2020 · Wellcome Open Research
54. Physiology Insights
    Richard M. Watanabe, Torben F. Hansen · 2016 · Springer eBooks
55. The Quality of Life among the Adult Population during COVID-19 in Saudi Arabia
    Reda Abdelmoaty Goweda, Turki Nizar Hammad, Zakaria Ali Khan, Ahmed Ali Alghamdi, Abdulaziz Otaywi Alyazidi, Abdullah G. Alharbi, Khalid Abdulrahman Almalki, Mohammed Abdullah Alzahrani, Ahmad Abdulaziz Alzubaidi · 2022 · World Family Medicine Journal/Middle East Journal of Family Medicine
56. Documentation of paediatric observations in an urgent care setting; a Quality Improvement Project
    Rahma Yusuf Ali · 2022 · World Family Medicine Journal/Middle East Journal of Family Medicine
57. Contrast-Induced Nephropathy among adults after administration of intravenous material in the Emergency department at King Abdul-Aziz university hospital
    Afaf S. Al-Saiari, Samiyah Alsaedi, Esraa Alzahran, Latifah Kutbi, Bothainah Abed A Alsahafi, Ghoson ghonem alharbi, Mostafa Abdelsalam, Abdullah A. Bakhsh · 2022 · World Family Medicine Journal/Middle East Journal of Family Medicine
58. Rare presentation of lower limb weakness, a case report
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59. Insulin Resistance Related to Metabolic Syndrome
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60. Clinical Audit Report on Adherence to Imaging Guidelines for Patients with Acute Low Back Pain in Airport Health Centre
    Hanan Taha Al Shamery, Wesam Abouamer, Neelufur Sulaiman Sait · 2022 · World Family Medicine Journal/Middle East Journal of Family Medicine
61. Advances in the Study of Cdkal1 Gene Polymorphisms Related to Susceptibility to Type 2 Diabetes
    新玲 毛 · 2023 · Advances in Clinical Medicine
62. In-silico analysis reveals hub genes and enriched pathways in Type 2 Diabetes Mellitus
    Prasad Gandham, R G SHARATHCHANDRA · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
63. Genetics of Type 2 Diabetes
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64. The Genetics of Diabetes
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65. An integration test based only on the maximum and minimum Z-scores for meta analysis
    Yuxin Zhang, Zhengbang Li · 2024 · Research Square
66. Diabetes mellitus with severe insulin resistance in a young male patient with a heterozygous pathogenic IRS1 frameshift variant
    Yamato Osawa, Nobutaka Ichiwata, Junko Kenmotsu, Tsuyoshi Okada, Yohei Masunaga, Tsutomu Ogata, Ichiro Morioka, Tatsuhiko Urakami · 2024 · Clinical Pediatric Endocrinology
67. Comparative Study on the Genetic Architecture of Type 2 Diabetes in Indian and Other Ethnic Groups: A Review
    Jyotsna Singh, Vijay Shankar Tripathi, Nachimuthu Senthil Kumar, Rajiv Kant, Jonathan A. Lal · 2024 · Current pharmacogenomics and personalized medicine (Online)/Current pharmacogenomics and personalized medicine
68. Demographic, Anthropometric, and Behavioral Predictors of Progression from Normal Glucose Regulation to Prediabetes
    2021 · American Diabetes Association eBooks
69. Genetics and Metabolism: How Genetics Affects Metabolic Syndrome in Various Populations
    Jiacheng Zhang · 2024 · Theoretical and Natural Science
70. Molecular mechanisms of reactive oxygen species effects in cardiometabolic syndrome
    Kocić Gordana · 2025 · Elsevier eBooks
71. Metabolomic Footprints of Lethal Versus Indolent Prostate Cancer
    Jing Ma, Clary B. Clish, Jorge E. Chavarro, Weiliang Qiu, Yin Cao, Yang Meng, Changzheng Yuan · 2014
72. Rôle des aminoacides ramifiés dans le déterminisme génétique de la résistance à l’insuline
    Sara Haydar · 2018 · theses.fr (ABES)
73. La décorine : un nouveau composant de la communication entre les muscles squelettiques et les cellules β pancréatiques
    Julien Cherfan · 2019 · theses.fr (ABES)
74. Paraoxonase 1 Gene Polymorphism and Its Influence on Cardiovascular Threat in Type 2 Diabetes Mellitus
    Shuvojit Moulik, Apoorva Tiwari, Gunjan Uttam, Awantika Das, Ayushi Singh · 2026 · European Journal of Biology
75. Genome-wide colocalization of body fat distribution GWAS and subcutaneous adipose eQTLs identifies SNX10, DGKQ, and CBX3 as candidate causal genes for cardiometabolic disease
    Muhammad Shahzad Iqbal · 2026 · medRxiv
76. Genetics and immunity: Mapping pathways in type II diabetes (T2D)
    Abdullah Khan, Rudrank Moharana · 2026 · Elsevier eBooks
77. Transcriptional and epigenomic analysis of insulin sensitivity in human adipocytes
    Qianbin Zhang, Audrey Zhou, Adam G. Maynard, Margo P. Emont, Christopher L. Jacobs, Soumya Nagesh, Thiago M. Batista, Renee M. Gibson, Yi Huang, Rama Kaalia et al. · 2026 · Cell Reports
78. When Genetics Meets the Mediterranean Diet Across Metabolic Diseases
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79. Epigenetische Prozesse beim Typ-2-Diabetes
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