Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders

Ernst, Thomas, Chase, Andrew J, Score, Joannah, Hidalgo-Curtis, Claire E, Bryant, Catherine, Jones, Amy V, Waghorn, Katherine, Zoi, Katerina +10 more·2010·Nature Genetics

Cited by (1,000)

Items 401–500 of 1,000

  1. EZH2-mediated upregulation of ROS1 oncogene promotes oral cancer metastasis
    C-H Shih, Y-J Chang, W-C Huang, T-H Jang, H.-J. Kung, W-C Wang, M-H Yang, M-C Lin, S-F Huang, S-W Chou et al. · 2017 · Oncogene
  2. Loss-of-function mutations in the histone methyltransferase EZH2 promote chemotherapy resistance in AML
    Julia Kempf, Sabrina Weser, Michael D. Bartoschek, Klaus Hans Metzeler, Binje Vick, Tobias Herold, Kerstin Völse, Raphael Mattes, Manuela Scholz, Lucas Esteban Wange et al. · 2021 · Scientific Reports
  3. JAK inhibitors in myeloproliferative neoplasms: Rationale, current data and perspective
    Ayalew Tefferi, Animesh Dev Pardanani · 2011 · Blood Reviews
  4. Annual Clinical Updates in Hematological Malignancies: A Continuing Medical Education Series: Polycythemia vera and essential thrombocythemia: 2011 update on diagnosis, risk‐stratification, and management
    Ayalew Tefferi · 2011 · American Journal of Hematology
  5. Genetics of the myeloproliferative neoplasms
    Omar Ibrahim Abdel-Wahab · 2011 · Current Opinion in Hematology
  6. Clinical Applications of Epigenetic Markers and Epigenetic Profiling in Myeloid Malignancies
    Michael A. McDevitt · 2012 · Seminars in Oncology
  7. Epigenetic regulators and their impact on therapy in acute myeloid leukemia
    F. Pastore, R. Levine · 2016 · Haematologica
  8. The molecular basis and clinical significance of genetic mutations identified in myelodysplastic syndromes
    Ling Zhang, Eric Padron, Jeffrey E. Lancet · 2014 · Leukemia Research
  9. Histone demethylase KDM4C regulates sphere formation by mediating the cross talk between Wnt and Notch pathways in colonic cancer cells
    Shinzo Yamamoto, Keisuke Tateishi, Yotaro Kudo, Keisuke Yamamoto, Takayuki Isagawa, Genta Nagae, Takuma Nakatsuka, Yoshinari Asaoka, Hideaki Ijichi, Yoshihiro Hirata et al. · 2013 · Carcinogenesis
  10. Array comparative genomic hybridization and sequencing of 23 genes in 80 patients with myelofibrosis at chronic or acute phase
    Mandy Brecqueville, Jérôme Rey, Raynier Devillier, Arnaud Guillé, R. Gillet, José Adélaı̈de, Véronique Gelsi‐Boyer, Christine Arnoulet, Max Chaffanet, Julien Mozziconacci et al. · 2013 · Haematologica
  11. KDM6B Counteracts EZH2-Mediated Suppression of IGFBP5 to Confer Resistance to PI3K/AKT Inhibitor Treatment in Breast Cancer
    Wenyu Wang, Keng Gat Lim, Min Feng, Yi Bao, Puay Leng Lee, Yu Cai, Yufeng Chen, Hao Zhang, Diego M. Marzese, Dave S.�B. Hoon et al. · 2018 · Molecular Cancer Therapeutics
  12. Clonogenic Multiple Myeloma Cells have Shared stemness Signature Associated with Patient Survival
    Renji Reghunathan, Chonglei Bi, Shaw Cheng Liu, Tze-Loong Koh, Tae‐Hoon Chung, Gaofeng Huang, Wee Joo Chng · 2013 · Oncotarget
  13. Epigenetic regulation of hematopoiesis
    Goro Sashida, Atsushi Iwama · 2012 · International Journal of Hematology
  14. Impact of isolated germline JAK2V617I mutation on human hematopoiesis
    Adam J. Mead, Onima Chowdhury, Christian Pecquet, Alexandra Dusa, Petter S. Woll, Deborah Atkinson, Adam Burns, J Score, Michelle J. Rugless, Ruth M Clifford et al. · 2013 · Blood
  15. Dysregulated Hematopoiesis Caused by Mammary Cancer Is Associated with Epigenetic Changes and Hox Gene Expression in Hematopoietic Cells
    Alexander Sio, Manreet K. Chehal, Kevin Tsai, Xueling Fan, Morgan E. Roberts, Brad H. Nelson, Jolanta E. Grembecka, Tomasz Cierpicki, Danielle L. Krebs, Kenneth W. Harder · 2013 · Cancer Research
  16. Epigenetic modification in chromatin machinery and its deregulation in pediatric brain tumors: Insight into epigenetic therapies
    Eléonore Maury, Rintaro Hashizume · 2017 · Epigenetics
  17. Oncogenic roles of enhancer of zeste homolog 1/2 in hematological malignancies
    Makoto Nakagawa, Issay Kitabayashi · 2018 · Cancer Science
  18. Targeting epigenetic machinery: Emerging novel allosteric inhibitors
    Fei Ye, Jing Li Huang, Hongbo Wang, Cheng Luo, Kehao Zhao · 2019 · Pharmacology & Therapeutics
  19. Histone H3K27 methylation modulates the dynamics of FANCD2 on chromatin to facilitate NHEJ and genome stability
    Zhang, Ye, Chang, Jian-Feng, Sun, Jin, Chen, Lu, Yang, Xiao-Mei, Tang, Huan-Yin, Jing, Yuan-Ya, Kang, Xuan, He, Zhi-Min, Wu, Jun-Yu et al. · 2018 · Journal of Cell Science
  20. Recent advances in understanding the molecular pathogenesis of myelodysplastic syndromes
    Austin Gladston Kulasekararaj, Azim M. Mohamedali, Ghulam Jeelani Mufti · 2013 · British Journal of Haematology
  21. Epigenetic therapies by targeting aberrant histone methylome in AML: molecular mechanisms, current preclinical and clinical development
    C T Tsai, Chi Wai Eric So · 2016 · Oncogene
  22. Polycomb Repressor Complex 2 in Genomic Instability and Cancer
    Zoe Veneti, Kalliopi K. Gkouskou, Aristides G. Eliopoulos · 2017 · International Journal of Molecular Sciences
  23. Mutations and deletions of the SUZ12 polycomb gene in myeloproliferative neoplasms
    Mandy Brecqueville, Nathalie Cervera, José Adélaı̈de, Jérôme Rey, Nadine Carbuccia, Max Chaffanet, Julien Mozziconacci, Norbert Vey, Daniel Birnbaum, Véronique Gelsi‐Boyer et al. · 2011 · Blood Cancer Journal
  24. The trithorax protein partner menin acts in tandem with EZH2 to suppress C/EBPα and differentiation in MLL-AF9 leukemia
    Austin T. Thiel, Zijie Feng, D. Pant, L. Chodosh, X. Hua · 2013 · Haematologica
  25. Targeting myeloproliferative neoplasms with JAK inhibitors
    Animesh Dev Pardanani, Ayalew Tefferi · 2011 · Current Opinion in Hematology
  26. Non-heritable genetics of human disease: spotlight on post-zygotic genetic variation acquired during lifetime
    Lars Anders Forsberg, Devin Absher, Jan Piotr Dumanski · 2012 · Journal of Medical Genetics
  27. Dissecting Disease Inheritance Modes in a Three-Dimensional Protein Network Challenges the “Guilt-by-Association” Principle
    Yu Guo, Xiaomu Wei, Jishnu Das, Andrew Grimson, Steven M. Lipkin, Andrew G. Clark, Haiyuan Yu · 2013 · The American Journal of Human Genetics
  28. Strategy for Robust Detection of Insertions, Deletions, and Point Mutations in CEBPA, a GC-Rich Content Gene, Using 454 Next-Generation Deep-Sequencing Technology
    Vera Großmann, Susanne Schnittger, Sonja Schindela, Hans‐Ulrich Klein, Christiane Eder, Martin Dugas, Wolfgang Kern, Torsten Haferlach, Claudia Haferlach, Alexander Kohlmann · 2011 · Journal of Molecular Diagnostics
  29. Environmental, lifestyle, and familial/ethnic factors associated with myeloproliferative neoplasms
    Lesley Ann Anderson, Andrew S. Duncombe, Maria Hughes, Moyra E. Mills, Jessica Claire Wilson, Mary Frances McMullin · 2011 · American Journal of Hematology
  30. Pathogenesis of Myeloproliferative Disorders
    Jyoti Nangalia, Jacob Grinfeld, Anthony Richard Green · 2016 · Annual Review of Pathology Mechanisms of Disease
  31. Cytogenetic Abnormalities in Myelodysplastic Syndromes: An Overview.
    Mohammad Faizan Zahid, Umair Arshad Malik, Momena Sohail, Irfan Nazir Hassan, Sara Ali, Muhammad Hamza Saad Shaukat · 2017 · PubMed Central
  32. Chronic Myelomonocytic Leukemia and Atypical Chronic Myeloid Leukemia: Novel Pathogenetic Lesions
    Hideki Muramatsu, Hideki Makishima, Jaroslaw Pawel Maciejewski · 2012 · Seminars in Oncology
  33. High EZH2 Protein Expression Is Associated with Poor Overall Survival in Patients with Luminal A Breast Cancer
    Si‐Hyong Jang, Jong Eun Lee, Mee‐Hye Oh, Ji‐Hye Lee, Hyun Deuk Cho, Kyung-Ju Kim, Sung Yong Kim, Sun Wook Han, Han Jo Kim, Sang Byung Bae et al. · 2016 · Journal of Breast Cancer
  34. High concordance of genomic and cytogenetic aberrations between peripheral blood and bone marrow in myelodysplastic syndrome (MDS)
    A M Mohamedali, Joop A. Gäken, Momin Ahmed, F MALIK, Alexander Smith, S Best, Syed A. Mian, Terry J. Gaymes, Robin M. Ireland, Austin Gladston Kulasekararaj et al. · 2015 · Leukemia
  35. Concise Review: Erythroid Versus Myeloid Lineage Commitment: Regulating the Master Regulators
    Linda Wolff, Rita Humeniuk · 2013 · Stem Cells
  36. Ezh2 regulates the Lin28/let-7 pathway to restrict activation of fetal gene signature in adult hematopoietic stem cells
    Motohiko Oshima, Nagisa Hasegawa, Makiko Mochizuki‐Kashio, Tomoya Muto, Satoru Miyagi, Shuhei Koide, Shogo Yabata, George Russel Wendt, Atsunori Saraya, Changshan Wang et al. · 2016 · Experimental Hematology
  37. Variegated RHOA mutations in human cancers
    Keisuke Kataoka, Seishi Ogawa · 2016 · Experimental Hematology
  38. CBX4 contributes to HIV‐1 latency by forming phase‐separated nuclear bodies and SUMOylating EZH2
    Liyang Wu, Ting Shuang Pan, Mo Zhou, Tao Chen, Shiyu Wu, Xi Lv, Jun Liu, Fei Yu, Yuanjun Guan, Bingfeng Liu et al. · 2022 · EMBO Reports
  39. TET2, ASXL1 and EZH2 mutations in Chinese with myelodysplastic syndromes
    Jieyu Wang, Xiaofei Ai, Robert Peter Gale, Zefeng Xu, Tiejun Qin, Liwei Fang, Hongli Zhang, Lijuan Pan, Naibo Hu, Yue Zhang et al. · 2012 · Leukemia Research
  40. Next Generation Sequencing in MPNs. Lessons from the Past and Prospects for Use as Predictors of Prognosis and Treatment Responses
    Vibe Skov · 2020 · Cancers
  41. A multi-centre phase 2 study of azacitidine in chronic myelomonocytic leukaemia
    M W Drummond, Christopher Pocock, Marjorie Boissinot, Juliet Mills, Julia M. Brown, Pierre Cauchy, Nicholas C.P. Cross, Suzanne Hartley, Jonathan Kell, Alexander J. Szubert et al. · 2014 · Leukemia
  42. Oncogenes, Proto-Oncogenes, and Lineage Restriction of Cancer Stem Cells
    Geoffrey Brown · 2021 · International Journal of Molecular Sciences
  43. Targeting cancer epigenetics: Linking basic biology to clinical medicine
    Keiko Shinjo, Yutaka Kondo · 2015 · Advanced Drug Delivery Reviews
  44. Updates in Cytogenetics and Molecular Markers in MDS
    Ramon Velasquez Tiu, Valeria Visconte, Fabı́ola Traina, Anita Schwandt, Jaroslaw Pawel Maciejewski · 2011 · Current Hematologic Malignancy Reports
  45. Nuclear–Cytoplasmic Transport Is a Therapeutic Target in Myelofibrosis
    Dongqing Yan, Anthony D. Pomicter, Srinivas Kiran Tantravahi, Clinton C. Mason, Anna V. Senina, Jonathan M. Ahmann, Qiang Wang, Hein Than, Ami B. Patel, William L. Heaton et al. · 2018 · Clinical Cancer Research
  46. A review of current therapeutics targeting the mitochondrial protease ClpP in diffuse midline glioma, H3 K27-altered
    Evangeline R. Jackson, Mika L. Persson, Cameron J Fish, Izac J. Findlay, Sabine Mueller, Javad Nazarian, Esther Hulleman, Jasper van der Lugt, Ryan J. Duchatel, Matthew D. Dun · 2023 · Neuro-Oncology
  47. Myeloproliferative Neoplasms: JAK2 Signaling Pathway as a Central Target for Therapy
    Florence Pasquier, Xénia Cabagnols, Lise Secardin, Isabelle Plo, William Vainchenker · 2014 · Clinical Lymphoma Myeloma & Leukemia
  48. Polycomb and trithorax opposition in development and disease
    Steven T. Poynter, Cigall Kadoch · 2016 · Wiley Interdisciplinary Reviews Developmental Biology
  49. Intersection of Epigenetic and Metabolic Regulation of Histone Modifications in Acute Myeloid Leukemia
    Abhinav Dhall, Barry M. Zee, Fangxue Yan, Mario Andres Blanco · 2019 · Frontiers in Oncology
  50. Epigenetic Regulation of Intestinal Stem Cells and Disease: A Balancing Act of DNA and Histone Methylation
    Alireza Lorzadeh, Maile Romero-Wolf, Ajay Goel, Unmesh Jadhav · 2021 · Gastroenterology
  51. Regulation of RNA Splicing: Aberrant Splicing Regulation and Therapeutic Targets in Cancer
    Koji Kitamura, Keisuke Nimura · 2021 · Cells
  52. DNA Methylation and Chromatin Remodeling: The Blueprint of Cancer Epigenetics
    Dipanjan Bhattacharjee, Smita Shenoy, Laxminarayana Kurady Bairy · 2016 · Scientifica
  53. EZH2 mutations and promoter hypermethylation in childhood acute lymphoblastic leukemia
    Vivien Schäfer, Jana Ernst, Jenny Rinke, Nils Winkelmann, James F. Beck, Andreas Hochhaus, Bernd Gruhn, Thomas Ernst · 2016 · Journal of Cancer Research and Clinical Oncology
  54. Cell-extrinsic hematopoietic impact of Ezh2 inactivation in fetal liver endothelial cells
    Wen Hao Neo, Christopher A.G. Booth, Emanuele Azzoni, Lijun Chi, Paul Delgado-Olguı́n, Marella F. T. R. De Bruijn, Sten Eirik W. Jacobsen, Adam J. Mead · 2018 · Blood
  55. The Genetics of Myelodysplastic Syndromes: Clinical Relevance
    Chiara Chiereghin, Erica Travaglino, Matteo Zampini, Elena Saba, Claudia Saitta, Elena Riva, Matteo Bersanelli, Matteo Giovanni Della Porta · 2021 · Genes
  56. Epigenetic regulation of adult stem cell function
    Lorenzo Rinaldi, Salvador Aznar Benitah · 2014 · FEBS Journal
  57. Hmga2 collaborates with JAK2V617F in the development of myeloproliferative neoplasms
    Koki Ueda, Kazuhiko Ikeda, Takayuki Ikezoe, Kayo Harada‐Shirado, Kazuei Ogawa, Yuko Hashimoto, Takahiro Sano, Hiroshi Ohkawara, Satoshi Kimura, Akiko Shichishima-Nakamura et al. · 2017 · Blood Advances
  58. Integrated genomic analyses identify frequent gene fusion events andVHLinactivation in gastrointestinal stromal tumors
    Guhyun Kang, Hongseok Yun, Choong-Hyun Sun, In Ho Park, Seungmook Lee, Jekeun Kwon, In‐Gu Do, Min Eui Hong, Michael Van Vrancken, Jeeyun Lee et al. · 2015 · Oncotarget
  59. Examining the impact of gene variants on histone lysine methylation
    Capucine Van Rechem, Johnathan R. Whetstine · 2014 · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
  60. Paraneoplastic inflammation in myelodysplastic syndrome or bone marrow failure: case series with focus on 5‐azacytidine and literature review
    Jochen J. Frietsch, Sebastian Dornaus, Thomas E. Neumann, Sebastian Scholl, Volker Schmidt, Christa Kunert, Herbert Gottfried Sayer, Andreas Hochhaus, Paul Graf La Rosée · 2014 · European Journal Of Haematology
  61. In aggressive variants of non-Hodgkin lymphomas, Ezh2 is strongly expressed and polycomb repressive complex PRC1.4 dominates over PRC1.2
    Lamia Abd Al-Kader, Takashi Oka, Katsuyoshi Takata, Xu Sun, Hiaki Sato, Ichiro Murakami, Tomohiro Toji, Akihiro Manabe, Hiroshi Kimurâ, Tadashi Yoshino · 2013 · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin
  62. Evi1 forms a bridge between the epigenetic machinery and signaling pathways
    Akihide Yoshimi, Mineo Kurokawa · 2011 · Oncotarget
  63. Single-Nucleotide Polymorphism Array Karyotyping in Clinical Practice: Where, When, and How?
    Aiko Sato‐Otsubo, Masashi Sanada, Seishi Ogawa · 2012 · Seminars in Oncology
  64. Histone Modifications
    Blerta Xhemalçe, Mark A. Dawson, Andrew J. Bannister · 2011 · Encyclopedia of Molecular Cell Biology and Molecular Medicine
  65. The Genetic Basis and Expanding Role of Molecular Analysis in the Diagnosis, Prognosis, and Therapeutic Design for Myelodysplastic Syndromes
    Grant E. Nybakken, Adam Bagg · 2014 · Journal of Molecular Diagnostics
  66. Protein-arginine Methyltransferase 1 (PRMT1) Methylates Ash2L, a Shared Component of Mammalian Histone H3K4 Methyltransferase Complexes
    Jill S. Napierala, Cecilia I. Zurita‐Lopez, Steven Gerard Clarke, Mark T. Bedford, Sharon Dent · 2011 · Journal of Biological Chemistry
  67. Chromatin-regulating proteins as targets for cancer therapy
    Takahiro Oike, Hideaki Ogiwara, Napapat Amornwichet, Takashi Nakano, Takashi Kohno · 2014 · Journal of Radiation Research
  68. Enhancer of zeste homologue 2 plays an important role in neuroblastoma cell survival independent of its histone methyltransferase activity
    Laurel Tabe Bate-Eya, Hinco Jasper Gierman, Marli E. Ebus, Jan Köster, Huib N. Caron, Rogier Versteeg, M. Emmy M. Dolman, Jan J. Molenaar · 2017 · European Journal of Cancer
  69. A Humanized Animal Model Predicts Clonal Evolution and Therapeutic Vulnerabilities in Myeloproliferative Neoplasms
    Hamza Celik, Ethan Krug, Christine R. Zhang, Wentao Han, Nancy Issa, Won Kyun Koh, Hassan Bjeije, Ostap Kukhar, Maggie Allen, Tindao Li et al. · 2021 · Cancer Discovery
  70. Canonical and non-canonical roles of the histone methyltransferase EZH2 in mammary development and cancer
    Woo Kyun Bae, Lothar G. Hennighausen · 2013 · Molecular and Cellular Endocrinology
  71. Integrated genome-wide genotyping and gene expression profiling reveals BCL11B as a putative oncogene in acute myeloid leukemia with 14q32 aberrations
    Sakina Abbas, M. A. Sanders, Annelieke Zeilemaker, W. M. C. Geertsma-Kleinekoort, Jasper E. Koenders, F. G. Kavelaars, Z. G. Abbas, S. Mahamoud, Isabel W. T. Chu, Remco Michiel Hoogenboezem et al. · 2014 · Haematologica
  72. Mutation Spectra of Histone Methyltransferases With Canonical SET Domains and EZH2-Targeted Therapy
    Masaru Katoh · 2015 · Epigenomics
  73. Recent advances in myelodysplastic syndromes: Molecular pathogenesis and its implications for targeted therapies
    Hironori Harada, Yuka Harada · 2015 · Cancer Science
  74. Key roles of histone methyltransferase and demethylase in leukemogenesis
    Akihide Yoshimi, Mineo Kurokawa · 2010 · Journal of Cellular Biochemistry
  75. Epigenetics and mutations in chronic myeloproliferative neoplasms
    Alessandro Maria Vannucchi, Flavia Biamonte · 2011 · Haematologica
  76. Elements of the Polycomb Repressor SU(Z)12 Needed for Histone H3-K27 Methylation, the Interface with E(Z), and In Vivo Function
    Aswathy N. Rai, Marcus L. Vargas, Liangjun Wang, Erica Andersen, Ellen Miller, Jeffrey A. Simon · 2013 · Molecular and Cellular Biology
  77. Easy or Not—The Advances of EZH2 in Regulating T Cell Development, Differentiation, and Activation in Antitumor Immunity
    Jiaqi Huang, Jie Zhang, Zhengyang Guo, Chen Li, Zhen Wei Tan, Junjie Wang, Jianling Yang, Lixiang Xue · 2021 · Frontiers in Immunology
  78. PRC2-Inactivating Mutations in Cancer Enhance Cytotoxic Response to DNMT1-Targeted Therapy via Enhanced Viral Mimicry
    Amish J. Patel, Sarah Warda, Jesper L.V. Mååg, Rohan Misra, Miguel A. Miranda-Román, Mohini R. Pachai, Cindy J. Lee, Dan Li, Naitao Wang, Gabriella Bayshtok et al. · 2022 · Cancer Discovery
  79. Mechanisms of Epigenetic Regulation of Leukemia Onset and Progression
    Panagiotis Ntziachristos, Jasper Mullenders, Thomas Trimarchi, Iannis Aifantis · 2013 · Advances in immunology
  80. Activating CBL mutations are associated with a distinct MDS/MPN phenotype
    Juliana Schwaab, Thomas Ernst, Philipp Erben, Jenny Rinke, Susanne Schnittger, Philipp Ströbel, Georgia Metzgeroth, Maximilian Mossner, Torsten Haferlach, Nicholas C.P. Cross et al. · 2012 · Annals of Hematology
  81. Profiling of aberrant DNA methylation in acute myeloid leukemia reveals subclasses of CG-rich regions with epigenetic or genetic association
    Claudia Gebhard, Dagmar Glatz, Lucia Schwarzfischer, Julia Wimmer, Sebastian Stasik, Margit Nuetzel, Daniel Heudobler, Reinhard Andreesen, Gerhard Ehninger, Christian Thiede et al. · 2018 · Leukemia
  82. Targeted re-sequencing analysis of 25 genes commonly mutated in myeloid disorders in del(5q) myelodysplastic syndromes
    Marta Fernández‐Mercado, Adam Burns, Andrea Pellagatti, Aristoteles A. N. Giagounidis, Ulrich Germing, Xabier Agirre, Felipe Prósper, Carlo Aul, Sally B. Killick, J. S. Wainscoat et al. · 2013 · Haematologica
  83. Lysine methylation in cancer: SMYD3‐MAP3K2 teaches us new lessons in the Ras‐ERK pathway
    Paula Colón‐Bolea, Piero Crespo · 2014 · BioEssays
  84. Histone modifying enzymes: novel disease biomarkers and assay development
    Fei Ma, Chun‐yang Zhang · 2015 · Expert Review of Molecular Diagnostics
  85. Histone demethylase JMJD3 at the intersection of cellular senescence and cancer
    Patrick M. Perrigue, Joseph Najbauer, Jan Barciszewski · 2016 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
  86. Molecular characterization of EZH2 mutant patients with myelodysplastic/myeloproliferative neoplasms
    Jenny Rinke, Jörg P. Müller, Markus F. Blaess, Andrew Chase, Manja Meggendorfer, Vivien Schäfer, Nils Winkelmann, Claudia Haferlach, Nicholas C.P. Cross, Andreas Hochhaus et al. · 2017 · Leukemia
  87. Histone Methylases and Demethylases Regulating Antagonistic Methyl Marks: Changes Occurring in Cancer
    Joyce Taylor‐Papadimitriou, Joy Burchell · 2022 · Cells
  88. Interpreting new molecular genetics in myelodysplastic syndromes
    Omar Ibrahim Abdel-Wahab, María E. Figueroa · 2012 · Hematology
  89. Role of TET2 Mutations in Myeloproliferative Neoplasms
    Elodie Pronier, François Delhommeau · 2011 · Current Hematologic Malignancy Reports
  90. Transcriptional and epigenetic networks in haematological malignancy
    Ngai Cheung, Chi Wai Eric So · 2011 · FEBS Letters
  91. Differential expression of enhancer of zeste homolog 2 (EZH2) protein in small cell and aggressive B-cell non-Hodgkin lymphomas and differential regulation of EZH2 expression by p-ERK1/2 and MYC in aggressive B-cell lymphomas
    Xuejun Tian, Ashley K. Pelton, Ali Shahsafaei, David M. Dorfman · 2016 · Modern Pathology
  92. Uses and Abuses of JAK2 and MPL Mutation Tests in Myeloproliferative Neoplasms
    Ayalew Tefferi, Pierre Noël, Curtis A. Hanson · 2011 · Journal of Molecular Diagnostics
  93. Strong expression of EZH2 and accumulation of trimethylated H3K27 in diffuse large B-cell lymphoma independent of cell of origin and EZH2 codon 641 mutation
    Zheng Gang Zhou, Juehua Gao, Relja Popovic, Kristy Lucile Wolniak, Vamsi Parimi, Jane N. Winter, Jonathan D. Licht, Yi‐Hua Chen · 2015 · Leukemia & lymphoma/Leukemia and lymphoma
  94. Context-specific regulation of cancer epigenomes by histone and transcription factor methylation
    Michalis E. Sarris, Konstantin Nikolaou, Iannis Talianidis · 2013 · Oncogene
  95. Roles of enhancer of zeste homolog 2: From skeletal muscle differentiation to rhabdomyosarcoma carcinogenesis
    Irene Marchesi, Antonio Giordano, Luigi Bagella · 2014 · Cell Cycle
  96. Copy number neutral loss of heterozygosity at 17p and homozygous mutations of TP53 are associated with complex chromosomal aberrations in patients newly diagnosed with myelodysplastic syndromes
    Karla Svobodová, Zuzana Zemanová, Halka Lhotská, Milena Novakova, Lucie Podskalska, Monika Beličková, Jana Březinová, Iveta Šárová, Silvia Izáková, Libuše Lizcová et al. · 2016 · Leukemia Research
  97. SF3B1 mutations in patients with myelodysplastic syndromes: The mutation is stable during disease evolution
    Chien‐Chin Lin, Hsin‐An Hou, Wen‐Chien Chou, Yuan‐Yeh Kuo, Shang‐Ju Wu, Chieh‐Yu Liu, Chien‐Yuan Chen, Mei‐Hsuan Tseng, Chi‐Fei Huang, Fen‐Yu Lee et al. · 2014 · American Journal of Hematology
  98. IDH1 and IDH2 mutations in myeloid neoplasms - Novel paradigms and clinical implications
    Mario Cazzola · 2010 · Haematologica
  99. The epigenetic landscape of T-cell acute lymphoblastic leukemia
    Joni Van der Meulen, Nadine Van Roy, Pieter Van Vlierberghe, Frank Speleman · 2014 · The International Journal of Biochemistry & Cell Biology
  100. The Yin and Yang of cancer genes
    Murali Dharan Bashyam, Srinivas Animireddy, Pratyusha Bala, Ashmala Naz, Sara A. George · 2019 · Gene