Increased exonic de novo mutation rate in individuals with schizophrenia

Girard, Simon L, Gauthier, Julie, Noreau, Anne, Xiong, Lan, Zhou, Sirui, Jouan, Loubna, Dionne-Laporte, Alexandre, Spiegelman, Dan, Henrion, Edouard, Diallo, Ousmane, Thibodeau, Pascale, Bachand, Isabelle, Bao, Jessie Y J, Tong, Amy Hin Yan, Lin, Chi-Ho, Millet, Bruno, Jaafari, Nematollah, Joober, Ridha, Dion, Patrick A, Lok, Si, Krebs, Marie-Odile, Rouleau, Guy A·2011·Nature Genetics

DOI 10.1038/ng.886

Cited by (435)

Items 101–200 of 435

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Cappi, C, Brentani, H, Lima, L, Sanders, S J, Zai, G, Diniz, B J, Reis, V N S, Hounie, A G, Conceição do Rosário, M, Mariani, D et al. · 2016 · Translational Psychiatry
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Akira Oka, Tomotaka Mabuchi, Akira OZAWA, Hidetoshi Inoko · 2012 · The Journal of Dermatology
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Jordi Soler, Lourdes Fañanás, Mara Parellada, Marie‐Odile Krebs, Guy Armand Rouleau, Mar Fatjó‐Vilas · 2018 · Journal of Psychiatry and Neuroscience
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Richards, A. L., Leonenko, G., Walters, J. T., Kavanagh, D. H., Rees, E. G., Evans, A., Chambert, K. D., Moran, J. L., Goldstein, J., Neale, B. M. et al. · 2016 · Human Molecular Genetics
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Amélie Piton, Loubna Jouan, Daniel L. Rochefort, Sylvia Dobrzeniecka, Karine Lachapelle, Patrick A. Dion, Julie Gauthier, Guy Armand Rouleau · 2012 · European Journal of Human Genetics
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Maynard V. Olson · 2012 · Annual Review of Genomics and Human Genetics
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Chahrour, Maria, O'Roak, Brian J., Santini, Emanuela, Samaco, Rodney C., Kleiman, Robin J., Manzini, M. Chiara · 2016 · The Journal of Neuroscience
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Elliott Rees, George Kirov, Michael C. O’Donovan, Michael John Owen · 2012 · Schizophrenia Bulletin
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Qian Wang, Qiongshi Lu, Hongyu Zhao · 2015 · Frontiers in Genetics
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Adolfo Sequeira, Brandi L. Rollins, Christophe Magnan, Mannis van Oven, Pierre Baldi, R Myers, Jack D. Barchas, Alan F. Schatzberg, Stanley J. Watson, Huda Akil et al. · 2015 · PLoS ONE
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János Réthelyi, Judit Benkovits, István Bitter · 2013 · Neuroscience & Biobehavioral Reviews
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Nathan Skene, Marcia M. Roy, Seth G. N. Grant · 2017 · eLife
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Rucha M. Wadapurkar, Renu Vyas · 2018 · Informatics in Medicine Unlocked
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Julien Couthouis, Alya R. Raphael, Roxana Daneshjou, A. Gitler · 2014 · PLoS Genetics
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Jiaxin Wu, Yanda Li, Rui Jiang · 2014 · PLoS Genetics
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Jibin John, Prachi Kukshal, Triptish Bhatia A, Kodavali V. Chowdari, V.L. Nimgaonkar, S.N. Deshpande, Bittianda Kuttapa Thelma · 2017 · Schizophrenia Research
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Andrew J. Pocklington, Michael C. O’Donovan, Michael John Owen · 2014 · European Journal of Neuroscience
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Chee‐Seng Ku, Mengchu Wu, D.N. Cooper, Nasheen Naidoo, Yudi Pawitan Y, Brendan Pang, Barry J. Iacopetta, Richie Soong · 2012 · Expert Review of Molecular Diagnostics
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Qiang Wang, Miao-Xin Li, Zhen-Xing Yang, Xun Hu, Hei-Man Wu, Pei-Yan Ni, H. Ren, W. Deng, Ming-Li Li, Xiao-Hong Ma et al. · 2015 · Scientific Reports
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Simon Girard, Cynthia V. Bourassa, Louis‐Philippe Lemieux Perreault, Marc‐André Legault, Amina Barhdadi, Amirthagowri Ambalavanan, Mara R. Brendgen, Frank Vitaro, Anne Noreau, Ginette Dionne et al. · 2016 · PLoS ONE
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Jhih-Rong Lin, Ying Cai, Quanwei Zhang, Wen Zhang, Rubén Nogales‐Cadenas, Zhengdong D. Zhang · 2016 · Genetics
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Zi‐Bing Jin, Zhongshan Li, Zhenwei Liu, Yi Wei Jiang, Xue‐Bi Cai, Jinyu Wu · 2017 · Biological reviews/Biological reviews of the Cambridge Philosophical Society
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Karun Kar Singh · 2013 · Clinical Genetics
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Yannis J Trakadis, Sameer Sardaar, Anthony Chen, Vanessa Fulginiti, Ankur Krishnan · 2018 · American Journal of Medical Genetics Part B Neuropsychiatric Genetics
Next-generation human genetics
Jay Shendure · 2011 · Genome biology
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Célia Kun‐Rodrigues, Christos Ganos, Rita João Guerreiro, Susanne A. Schneider, Claudia Schulte, Suzanne Lesage, Lee Darwent, Peter Holmans, Andrew Singleton, Kailash P. Bhatia et al. · 2015 · Human Molecular Genetics
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Zhonghua Hu, Shouguo Gao, Daniel M. Lindberg, Debabrata Panja, Yoshi Wakabayashi, Keshen Li, Joel E. Kleinman, Jun Zhu, Zheng Li · 2019 · Translational Psychiatry
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Panos Roussos, Boris Guennewig, Dominik C. Kaczorowski, Guy Barry, Kristen Brennand · 2016 · JAMA Psychiatry
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Elliott Rees, Noa Carrera, Joanne Morgan, Kirsty Hambridge, Valentina Escott‐Price, Andrew J. Pocklington, Alexander L. Richards, Antonio F. Pardiñas, Colm McDonald, Gary J Donohoe et al. · 2018 · Biological Psychiatry
Making sense of deep sequencing
David A Goldman, Katharina Domschke · 2014 · The International Journal of Neuropsychopharmacology
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Govardhan Bale, Ravikanth Vishnubhotla, Mitnala Sasikala, Mithun Sharma, Rao N. Padaki, Smita C. Pawar, Reddy N. Duvvur · 2019 · Journal of Clinical and Experimental Hepatology
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Morris, D. W., Pearson, R. D., Cormican, P., Kenny, E. M., O'Dushlaine, C. T., Perreault, L.-P. L., Giannoulatou, E., Tropea, D., Maher, B. S., Wormley, B. et al. · 2014 · Human Molecular Genetics
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Alexandros Hatzimanolis, John A. McGrath, R Wang, T Li, Philip C. Wong, Gerald Nestadt, Paula S Wolyniec, David L. Valle, Ann E. Pulver, Dimitrios Avramopoulos · 2013 · Translational Psychiatry
Whole genome sequencing for quantifying germline mutation frequency in humans and model species: Cautious optimism
Marc A. Beal, Travis C. Glenn, Christopher M. Somers · 2011 · Mutation Research/Reviews in Mutation Research
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Ariel Ernesto Cariaga-Martínez, Jerónimo Sáiz-Ruiz, Raúl Alelú‐Paz · 2016 · Frontiers in Neuroscience
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Calliope Athena Dendrou, Gil McVean, Lars H. Fugger · 2016 · Nature Reviews Neurology
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Schizophrenia Genetics: Putting All the Pieces Together
Simon Girard, Patrick A. Dion, Guy Armand Rouleau · 2012 · Current Neurology and Neuroscience Reports
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Wenqing Fu, Timothy D. O’Connor, Joshua M. Akey · 2013 · Current Opinion in Genetics & Development
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Chee‐Seng Ku, Eng King Tan, D.N. Cooper · 2013 · Journal of Medical Genetics
Genetic studies of schizophrenia: an update
Jingchun Chen, Fei Cao, Lanfen Liu, Lina Wang, Xiangning Chen · 2015 · Neuroscience Bulletin
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Xiao Chang, Leandro de A. Lima, Yichuan Liu, Jin Li, Qingqin S. Li, Patrick M. Abou‐Sleiman, Hakon H. Hakonarson · 2018 · Frontiers in Genetics
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Andreas J. Forstner, Sascha B. Fischer, Lorena M. Schenk, Jana Strohmaier, Anna Maaser‐Hecker, Céline S. Reinbold, Sugirthan Sivalingam, Julian Hecker, Fabian Streit, Franziska Degenhardt et al. · 2020 · Translational Psychiatry
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Yongzhuang Liu, Bingshan Li, Renjie Tan, Xiaolin Zhu, Yadong Wang · 2014 · Bioinformatics
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Matthew A. Schreiber, Michael O. Dorschner, Debby W. Tsuang · 2013 · American Journal of Medical Genetics Part B Neuropsychiatric Genetics
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Ming Li, Cuijuan Shi, Yongyong Shi, Xiong‐Jian Luo, Xue‐Bin Zheng, Zhiqiang Li, Jianjun Liu, Siow‐Ann Chong, Jimmy Lee, Yi Wang et al. · 2012 · American Journal of Medical Genetics Part B Neuropsychiatric Genetics
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Zhifan Zhou, Zhengmao Hu, Lu Zhang, Zhaoting Hu, Haihong Liu, Zhening Liu, Juan Du, Jingping Zhao, Lin Zhou, Kun Xia et al. · 2016 · Scientific Reports
Consensus paper of the WFSBP Task Force on Biological Markers: Criteria for biomarkers and endophenotypes of schizophrenia part II: Cognition, neuroimaging and genetics
A. Schmitt, D. Rujescu, M. Gawlik, A. Hasan, K. Hashimoto, Sylvain Iceta, M. Jarema, J. Kambeitz, S. Kasper, D. Keeser et al. · 2016 · World Journal of Biological Psychiatry
Incorporating Functional Information in Tests of Excess De Novo Mutational Load
Yu Jiang, Yujun Han, Slavé Petrovski, Kouros Owzar, David B. Goldstein, Andrew S. Allen · 2015 · The American Journal of Human Genetics
Parental age and the risk of bipolar disorders
Roshan Chudal, Mika Gissler, Dan Sucksdorff, Venla Lehti, Auli Suominen, Susanna Hinkka‐Yli‐Salomäki, Alan S. Brown, André Sourander · 2014 · Bipolar Disorders
Investigation of rare variants in LRP1, KPNA1, ALS2CL and ZNF480 genes in schizophrenia patients reflects genetic heterogeneity of the disease
Loubna Jouan, Simon Girard, Sylvia Dobrzeniecka, Amirthagowri Ambalavanan, Marie‐Odile Krebs, Ridha Joober, Julie Gauthier, Patrick A. Dion, Guy Armand Rouleau · 2013 · Behavioral and Brain Functions
Genetic susceptibility in obsessive-compulsive disorder
Thomas V. Fernandez, James Frederick Leckman, Christopher Pittenger · 2018 · Handbook of clinical neurology
Cancer therapy and risk of congenital malformations in children fathered by men treated for testicular germ-cell cancer: A nationwide register study
Yahia Al-Jebari, Ingrid Cecilia Glimelius, Carina Nord, Gabriella Elisabeth Cohn-Cedermark, Olof Ståhl, Torgrim Tandstad, Allan Jensen, Hege Sagstuen Haugnes, Gedske Daugaard, Lars Rylander et al. · 2019 · PLoS Medicine
Novel genetic susceptibility loci identified by family based whole exome sequencing in Han Chinese schizophrenia patients
Mo Li, Lu Shen, Luan Chen, Cong Huai, Hailiang Huang, Xi Wu, Chao Yang, Jingsong Ma, Wei Zhou, Huihui Du et al. · 2020 · Translational Psychiatry
Risk genes for schizophrenia: translational opportunities for drug discovery.
C. Winchester, J. Pratt, B. Morris · 2014 · Pharmacology and Therapeutics
The Candidate Schizophrenia Risk Gene DGCR2 Regulates Early Steps of Corticogenesis
Aude Molinard‐Chenu, Alexandre G. Dayer · 2017 · Biological Psychiatry
Transcriptome Analysis of Post-Mortem Brain Tissue Reveals Up-Regulation of the Complement Cascade in a Subgroup of Schizophrenia Patients
Eva Lindholm Carlström, Adnan Niazi, Mitra Etemadikhah, Jonatan Halvardson, Stefan Enroth, Craig A. Stockmeier, Grażyna Rajkowska, Bo Nilsson, Lars Feuk · 2021 · Genes
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Myeong-Heui Kim, Il Bin Kim, Junehawk Lee, Do Hyeon Cha, Sang Min Park, Ja Hye Kim, Ryunhee Kim, Jun Sung Park, Yohan An, Kyungdeok Kim et al. · 2021 · Biological Psychiatry
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Nicholas E. Clifton, Elliott Rees, Peter Holmans, Antonio F. Pardiñas, Janet C Harwood, Arianna Di Florio, George Kirov, James Walters, Michael C. O’Donovan, Michael John Owen et al. · 2020 · Molecular Psychiatry
Complete plastome sequencing from Toona (Meliaceae) and phylogenomic analyses within Sapindales
Nan Lin, Michael J. Moore, Tao Deng, Hang Sun, Linsen Yang, Yanxia Sun, Hengchang Wang · 2018 · Applications in Plant Sciences
Novel treatment strategies for schizophrenia from improved understanding of genetic risk
B. Morris, J. Pratt · 2014 · Clinical Genetics
Transcriptome analysis of fibroblasts from schizophrenia patients reveals differential expression of schizophrenia-related genes
Mitra Etemadikhah, Adnan Niazi, Lennart Wetterberg, Lars Feuk · 2020 · Scientific Reports
From next-generation sequencing alignments to accurate comparison and validation of single-nucleotide variants: the pibase software
Michael Förster, Peter Forster, Abdou ElSharawy, Georg Hemmrich, Benjamin Kreck, Michael Wittig, Ingo Thomsen, Björn Stade, Matthias Barann, David Ellinghaus et al. · 2012 · Nucleic Acids Research
Identification of somatic mutations in monozygotic twins discordant for psychiatric disorders
Masaki Nishioka, Miki Bundo, Junko Ueda, Akane Yoshikawa, Fumichika Nishimura, Tsukasa Sasaki, Chihiro Kakiuchi, Kiyoto Kasai, Tadafumi Kato, Kazuya Iwamoto · 2018 · Schizophrenia
Aging genomes: A necessary evil in the logic of life
Vijg, Jan · 2014 · BioEssays
A de novo nonsense mutation of the FUS gene in an apparently familial amyotrophic lateral sclerosis case
Andrea Calvo, Cristina Moglia, Antonio Canosa, Maura Brunetti, Marco Barberis, Bryan J. Traynor, Giovanna Carrara, Consuelo Valentini, Gabriella Restagno, Adriano Chiò · 2014 · Neurobiology of Aging
Following the genes: a framework for animal modeling of psychiatric disorders
Kevin J. Mitchell, Z. Josh Huang, Bita Moghaddam, Akira Sawa · 2011 · BMC Biology
Significant Strain Variation in the Mutation Spectra of Inbred Laboratory Mice
Beth L. Dumont · 2019 · Molecular Biology and Evolution