Mutations in the mitochondrial GTPase mitofusin 2 cause Charcot-Marie-Tooth neuropathy type 2A
Züchner, Stephan, Mersiyanova, Irina V, Muglia, Maria, Bissar-Tadmouri, Nisrine, Rochelle, Julie, Dadali, Elena L, Zappia, Mario, Nelis, Eva, Patitucci, Alessandra, Senderek, Jan, Parman, Yesim, Evgrafov, Oleg, Jonghe, Peter De, Takahashi, Yuji, Tsuji, Shoij, Pericak-Vance, Margaret A, Quattrone, Aldo, Battologlu, Esra, Polyakov, Alexander V, Timmerman, Vincent, Schröder, J Michael, Vance, Jeffery M·2004·Nature Genetics
DOI 10.1038/ng1341
Cited by (1,000)
Items 401–500 of 1,000
- The heat shock response and small molecule regulatorsMargaret K. Kurop, Cormac M. Huyen, John H. Kelly, Brian S. J. Blagg · 2021 · European Journal of Medicinal Chemistry
- The Dynamics of the Mitochondrial Organelle as a Potential Therapeutic TargetRuth Anne Stetler, Rehana K. Leak, Yanqin Gao, Jun Chen · 2012 · Journal of Cerebral Blood Flow & Metabolism
- Mitochondrial Dynamics in Alzheimerʼs DiseaseDavid Bonda, Xinglong Wang, George L. Perry, Mark A. Smith, Xiongwei Zhu · 2010 · Drugs & Aging
- Drp1 levels constitutively regulate mitochondrial dynamics and cell survival in cortical neuronsTakuma Uo, Jenny Dworzak, Chizuru Kinoshita, Denise M. Inman, Yoshito Kinoshita, Philip J. Horner, Richard S. Morrison · 2009 · Experimental Neurology
- Regulation of mitochondrial morphology and function by O-GlcNAcylation in neonatal cardiac myocytesAyako Makino, Jorge Suárez, Thomas Gawlowski, Wenlong Han, Hong Wang, Brian T. Scott, WOLFGANG H. DILLMANN · 2011 · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
- Hepatocyte Mitochondrial Dynamics and Bioenergetics in Obesity-Related Non-Alcoholic Fatty Liver DiseaseAigli‐Ioanna Legaki, Ioannis I. Moustakas, Michalina Sikorska, Grigorios Papadopoulos, Rallia-Iliana Velliou, Antonios Chatzigeorgiou · 2022 · Current Obesity Reports
- Optic atrophy 1 mediates mitochondria remodeling and dopaminergic neurodegeneration linked to complex I deficiencyDavid Ramonet, Céline Perier, Ariadna Recasens, Benjamin Dehay, Jordi Bové, Veronica Costa, Luca Scorrano, Miquel Vila · 2012 · Cell Death and Differentiation
- β‐Tubulin mutations that cause severe neuropathies disrupt axonal transportShinsuke Niwa, Hironori Takahashi, Nobutaka Hirokawa · 2013 · The EMBO Journal
- S-Nitrosylation of Critical Protein Thiols Mediates Protein Misfolding and Mitochondrial Dysfunction in Neurodegenerative DiseasesTomohiro Nakamura, Stuart A. Lipton · 2010 · Antioxidants and Redox Signaling
- Unravelling mitochondrial pathways to P arkinson's diseaseIvana Celardo, L. Miguel Martins, Sonia Gandhi · 2013 · British Journal of Pharmacology
- Structural and functional analysis of MiD51, a dynamin receptor required for mitochondrial fissionViviane Richter, Catherine S. Palmer, Laura Danielle Osellame, Abeer Prakash Singh, Kirstin Elgass, David A. Stroud, Hiromi Sesaki, Marc Kvansakul, Michael T. Ryan · 2014 · The Journal of Cell Biology
- Mechanisms of Disease: a molecular genetic update on hereditary axonal neuropathiesStephan L. Zuchner, Jeffery M. Vance · 2006 · Nature Clinical Practice Neurology
- Mitochondrial Morphology and Fundamental Parameters of the Mitochondrial Respiratory Chain Are Altered in Caenorhabditis elegans Strains Deficient in Mitochondrial Dynamics and Homeostasis ProcessesAnthony L. Luz, John P. Rooney, Laura L. Maurer, Claudia P. Gonzalez, Dong Hoon Song, Joel N. Meyer · 2015 · PLoS ONE
- Structural basis for GTP hydrolysis and conformational change of MFN1 in mediating membrane fusionLiming Yan, Yuanbo Qi, Xiaofang Huang, Caiting Yu, Lan Lan, Xiangyang Guo, Zihe Rao, Junjie Hu, Zhiyong Lou · 2018 · Nature Structural & Molecular Biology
- Different clinical and magnetic resonance imaging features between Charcot–Marie–Tooth disease type 1A and 2AKi Wha Chung, Bum Chun Suh, Michael E. Shy, S.Y. Cho, Jeong Hyun Yoo, S.W. Park, Heui‐Soo Moon, K.D. Park, Kyoung‐Gyu Choi, Sơn Trần Kim et al. · 2008 · Neuromuscular Disorders
- Insights into amyloid-β-induced mitochondrial dysfunction in Alzheimer diseaseXinglong Wang, Bo Su, George L. Perry, Mark A. Smith, Xiongwei Zhu · 2007 · Free Radical Biology and Medicine
- HIV alters neuronal mitochondrial fission/fusion in the brain during HIV-associated neurocognitive disordersJerel Adam Fields, Elisabeth Serger, Sofia Campos, Ajit S. Divakaruni, Changyoun Kim, Kendall Smith, Margarita Trejo, Anthony Adame, Brian J. Spencer, Edward M. Rockenstein et al. · 2015 · Neurobiology of Disease
- Mitochondrial dysfunction and pathophysiology of Charcot–Marie–Tooth disease involving GDAP1 mutationsJulien Cassereau, Arnaud Chevrollier, Naïg Guéguen, Valérie Desquiret‐Dumas, Christophe Verny, Guillaume Nicolas, Frédéric Dubas, Patrizia Amati‐Bonneau, Pascal Reynier, Dominique Bonneau et al. · 2010 · Experimental Neurology
- Altered interplay between endoplasmic reticulum and mitochondria in Charcot–Marie–Tooth type 2A neuropathyNathalie Bernard‐Marissal, Gerben van Hameren, Manisha Juneja, Christophe Pellegrino, Lauri M. Louhivuori, Luca Bartesaghi, Cylia Rochat, Omar El Mansour, Jean‐Jacques Médard, Marie Croisier et al. · 2019 · Proceedings of the National Academy of Sciences
- Restoring mitofusin balance prevents axonal degeneration in a Charcot-Marie-Tooth type 2A modelYueqin Zhou, Sharon Carmona, A.K.M. Ghulam Muhammad, Shaughn Bell, Jesse Landeros, Michael Vazquez, Ritchie Ho, Antonietta Franco, Bin Lü, Gerald W. Dorn et al. · 2019 · Journal of Clinical Investigation
- Regulation of mitochondrial dynamics: convergences and divergences between yeast and vertebratesJian Zhao, Urban Lendahl, Monica Nistér · 2012 · Cellular and Molecular Life Sciences
- Two Deubiquitylases Act on Mitofusin and Regulate Mitochondrial Fusion along Independent PathwaysFabian den Brave, Gunnar Dittmar, Thomas Langer, Mafalda Escobar‐Henriques · 2013 · Molecular Cell
- Hyperglycemia Alters Mitochondrial Fission and Fusion Proteins in Mice Subjected to Cerebral Ischemia and ReperfusionSantosh Kumari, Lavita Anderson, Stephanie Farmer, Suresh L. Mehta, P. Andy Li · 2012 · Translational Stroke Research
- Lysosomal Regulation of Inter-mitochondrial Contact Fate and Motility in Charcot-Marie-Tooth Type 2Yvette C. Wong, Wesley Peng, Dimitri Krainc · 2019 · Developmental Cell
- Mitochondrial biogenesis as a therapeutic target for traumatic and neurodegenerative CNS diseasesEpiphani C. Simmons, Natalie E. Scholpa, Rick G. Schnellmann · 2020 · Experimental Neurology
- Mitofusin 2 plays a role in oocyte and follicle development, and is required to maintain ovarian follicular reserve during reproductive agingMan Zhang, Muhammed Burak Bener, Zongliang Jiang, Tianren Wang, Ecem Esencan, Richard Scott, Tamás L. Horváth, Emre U Seli · 2019 · Aging
- OPA1 Deficiency Associated with Increased Autophagy in Retinal Ganglion Cells in a Murine Model of Dominant Optic AtrophyKathryn White, Vanessa J. Davies, Vanessa E. Hogan, Malgorzata J. Piechota, Philip P. Nichols, Douglass M. Turnbull, Marcela Votruba · 2009 · Investigative Ophthalmology & Visual Science
- Oxidative Stress and Altered Mitochondrial Function in Neurodegenerative Diseases: Lessons From Mouse ModelsJosé Carlos Fernández-Checa, A. Fernandez, Albert Morales, Montserrat Marı́, Carmen García‐Ruiz, Anna Colell · 2010 · CNS & Neurological Disorders - Drug Targets
- The Interplay between Mitochondrial Morphology and Myomitokines in Aging SarcopeniaRomanello, Vanina · 2020 · International Journal of Molecular Sciences
- Anti-Tumor Effects of Mfn2 in Gastric CancerGeer Zhang, Hailong Jin, Xian-Ke Lin, Chao Chen, Xiaosun Liu, Qing Zhang, Jiren Yu · 2013 · International Journal of Molecular Sciences
- How mitochondria fuseShelly Meeusen, Jodi M. Nunnari · 2005 · Current Opinion in Cell Biology
- The Maintenance of Mitochondrial DNA Integrity and Dynamics by Mitochondrial MembranesJames Chapman, Yi Shiau Ng, Thomas J. J. Nicholls · 2020 · Life
- Neuronal metabolic rewiring promotes resilience to neurodegeneration caused by mitochondrial dysfunctionElisa Motori, Ilian Atanassov, Sandra M.V. Kochan, Kat Folz‐Donahue, Vignesh Sakthivelu, Patrick Giavalisco, Nicolas Toni, Julien Puyal, Nils‐Göran Larsson · 2020 · Science Advances
- Shortened internodal length of dermal myelinated nerve fibres in Charcot-Marie-Tooth disease type 1AMario Saporta, I. Katona, Richard A. Lewis, S. Masse, Michael E. Shy, J. Li · 2009 · Brain
- Neuroprotection by estrogen in the brain: the mitochondrial compartment as presumed therapeutic targetSusanne Arnold, Cordian Beyer · 2009 · Journal of Neurochemistry
- Opening the doors to cytochrome c: Changes in mitochondrial shape and apoptosisLuca Scorrano · 2009 · The International Journal of Biochemistry & Cell Biology
- miR-761 regulates the mitochondrial network by targeting mitochondrial fission factorBo Long, Kun Wang, Na Li, Iram Murtaza, Jing Ying Xiao, Yuan Yuan Fan, Cui-Yun Liu, Wen Hui Li, Zheng Cheng, Peifeng Li · 2013 · Free Radical Biology and Medicine
- A practical approach to the genetic neuropathiesAlexander Martin Rossor, Matthew R. B. Evans, Mary M. Reilly · 2015 · Practical Neurology
- Mitochondrial dysfunction in glaucoma: Understanding genetic influencesGerassimos Lascaratos, David F. Garway‐Heath, Colin Eric Willoughby, Kai‐Yin Chau, Anthony H.V. Schapira · 2011 · Mitochondrion
- Mechanistic perspective of mitochondrial fusion: Tubulation vs. fragmentationMafalda Escobar‐Henriques, Fabian den Brave · 2012 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
- Mitochondrial oxidative phosphorylation and energetic status are reflected by morphology of mitochondrial network in INS-1E and HEP-G2 cells viewed by 4Pi microscopyLydie Plecitá‐Hlavatá, Mark D. Lessard, Jitka Šantorová, Joerg Bewersdorf, Petr Ježek · 2008 · Biochimica et Biophysica Acta (BBA) - Bioenergetics
- The Mutational Spectrum in a Cohort of Charcot-Marie-Tooth Disease Type 2 among the Han Chinese in TaiwanKon‐Ping Lin, Bing‐Wen Soong, Chih‐Chao Yang, Li-Wen Huang, Ming‐Hong Chang, I‐Hui Lee, Antony Antonellis, Yi‐Chung Lee · 2011 · PLoS ONE
- Histopathological Findings in Hereditary Motor and Sensory Neuropathy of Axonal Type With Onset in Early Childhood Associated WithMitofusin 2MutationsJean‐Michel Vallat, Robert Ouvrier, John David Pollard, Corinne Magdelaine, Danqing Zhu, Garth A. Nicholson, S. Grew, Monique M. Ryan, Benoît Funalot · 2008 · Journal of Neuropathology & Experimental Neurology
- REEP1 mutations in SPG31: Frequency, mutational spectrum, and potential association with mitochondrial morpho-functional dysfunctionCyril Goizet, Christel Depienne, Giovanni Bénard, A. Boukhris, Emeline Mundwiller, Guilhem Solé, Isabelle Coupry, Julie Pilliod, Marie‐Laure Martin‐Négrier, Estelle Fédirko et al. · 2011 · Human Mutation
- Charcot–Marie–Tooth disease CMT4A: GDAP1 increases cellular glutathione and the mitochondrial membrane potentialRebecca Noack, Svenja Frede, Philipp Albrecht, Nadine Henke, Annika Pfeiffer, Katrin Knoll, Thomas Dehmel, Gerd Meyer zu Hörste, Mark Stettner, Bernd C. Kieseier et al. · 2011 · Human Molecular Genetics
- Autophagosome biogenesis and human healthTsuyoshi Kawabata, Tamotsu Yoshimori · 2020 · Cell Discovery
- Mutated mitofusin 2 presents with intrafamilial variability and brain mitochondrial dysfunctionRoberto Del Bo, Maurizio Gualtiero Moggio, Mario Rango, S. Bonato, Maria Grazia D’Angelo, Serena Ghezzi, Giovanni Airoldi, Maria Teresa Bassi, Michela Guglieri, Laura Napoli et al. · 2008 · Neurology
- The optic nerve: A “mito-window” on mitochondrial neurodegenerationAlessandra Maresca, Chiara La Morgia, Leonardo Caporali, Maria Lucia Valentino, Valério Carelli · 2012 · Molecular and Cellular Neuroscience
- DRP1 Suppresses Leptin and Glucose Sensing of POMC NeuronsAnna Natalizia Santoro, Michela Campolo, Chen Liu, Hiromi Sesaki, Rosaria Meli, Zhong-Wu Liu, Jung Dae Kim, Sabrina Diano · 2017 · Cell Metabolism
- Functional Interplay between Cristae Biogenesis, Mitochondrial Dynamics and Mitochondrial DNA IntegrityArun Kumar Kondadi, Ruchika Anand, Andreas S. Reichert · 2019 · International Journal of Molecular Sciences
- Intertwined and Finely Balanced: Endoplasmic Reticulum Morphology, Dynamics, Function, and DiseasesHannah T. Perkins, Viki Allan · 2021 · Cells
- Mitochondrial Fusion, Fission, and Mitophagy in Cardiac Diseases: Challenges and Therapeutic OpportunitiesDébora da Luz Scheffer, Adriana Ann Garcia, Lucia Lee, Daria Mochly‐Rosen, Julio Cesar Batista Ferreira · 2022 · Antioxidants and Redox Signaling
- Preventing Ca2+-mediated nitrosative stress in neurodegenerative diseases: Possible pharmacological strategiesTomohiro Nakamura, Stuart A. Lipton · 2010 · Cell Calcium
- The Role of the Transmembrane RING Finger Proteins in Cellular and Organelle FunctionNobuhiro Nakamura · 2011 · Membranes
- Transgenic Control of Mitochondrial Fission Induces Mitochondrial Uncoupling and Relieves Diabetic Oxidative StressChad A. Galloway, Hakjoo Lee, S. Nejjar, Bong Sook Jhun, Tianzheng Yu, Wei Hsu, Yisang Yoon · 2012 · Diabetes
- Human biallelic MFN2 mutations induce mitochondrial dysfunction, upper body adipose hyperplasia, and suppression of leptin expressionNuno Rocha, David A. Bulger, Andrea Frontini, Hannah L. Titheradge, Sigrid Bjerge Gribsholt, Rachel G. Knox, Matthew Page, Julie R. Harris, Felicity Payne, Claire Adams et al. · 2017 · eLife
- EMB2473/MIRO1, anArabidopsisMiro GTPase, Is Required for Embryogenesis and Influences Mitochondrial Morphology in PollenShohei Yamaoka, Christopher John Leaver · 2008 · The Plant Cell
- Biological Implications of Differential Expression of Mitochondrial-Shaping Proteins in Parkinson’s DiseaseSara Rocha, Ana Freitas, S. Guimarães, Rui Miguel Pinheiro Vitorino, Miguel Aroso, María Gómez-Lázaro · 2017 · Antioxidants
- Identification of the Drosophila Ortholog of HSPB8Serena Carra, Alessandra Boncoraglio, Bart Kanon, Jeanette F. Brunsting, Melania Minoia, Anil Rana, Michel J. Vos, Kay Seidel, Ody C.M. Sibon, Harm H. Kampinga · 2010 · Journal of Biological Chemistry
- CHCHD10 variant p.(Gly66Val) causes axonal Charcot-Marie-Tooth diseaseMari Auranen, Emil Ylikallio, Maria Shcherbii, Anders E. Paetau, Sari Kiuru‐Enari, Jussi P. Toppila, Henna Tyynismaa · 2015 · Neurology Genetics
- Structural implications of mitochondrial dynamicsJürgen Bereiter‐Hahn, Monika Vöth, Sören Mai, Marina Jendrach · 2008 · Biotechnology Journal
- Diagnosis of Charcot‐Marie‐Tooth DiseaseIsabel Banchs, Carlos Casasnovas, Antonia Albertí, Laura Jorge, Mónica Povedano, Jordi Montero, Juan Antonio Martínez‐Matos, Vı́ctor Volpini · 2009 · BioMed Research International
- Modulation of mitochondrial morphology by bioenergetics defects in primary human fibroblastsOlwenn Guillery, Florence Malka, Paule Frachon, Dan Miléa, Manuel Rojo, Anne Lombès · 2008 · Neuromuscular Disorders
- Intermediate Filaments as Organizers of Cellular Space: How They Affect Mitochondrial Structure and FunctionNicole Schwarz, Rudolf E. Leube · 2016 · Cells
- The Spinocerebellar Ataxia 12 Gene Product and Protein Phosphatase 2A Regulatory Subunit Bβ2 Antagonizes Neuronal Survival by Promoting Mitochondrial FissionRuben Karim Dagda, Ronald A. Merrill, J. Thomas Cribbs, Yucui Chen, Johannes Wilhelm Hell, Yuriy M. Usachev, Stefan Strack · 2008 · Journal of Biological Chemistry
- Instability of the Mitofusin Fzo1 Regulates Mitochondrial Morphology during the Mating Response of the Yeast Saccharomyces cerevisiaeAlbert Neutzner, Richard J. Youle · 2005 · Journal of Biological Chemistry
- Shedding light on mitophagy in neurons: what is the evidence for PINK1/Parkin mitophagy in vivo?Nadia Cummins, Jürgen Götz · 2017 · Cellular and Molecular Life Sciences
- Endoplasmic reticulum and mitochondria in diseases of motor and sensory neurons: a broken relationship?Nathalie Bernard‐Marissal, Roman Chrast, Bernard Laurent Schneider · 2018 · Cell Death and Disease
- Traffic accidents: Molecular genetic insights into the pathogenesis of the hereditary spastic paraplegiasCynthia Soderblom, Craig D. Blackstone · 2005 · Pharmacology & Therapeutics
- A history of mitochondrial diseasesSalvatore DiMauro · 2010 · Journal of Inherited Metabolic Disease
- Mitochondria in lung diseasesBharathi Aravamudan, Michael A Thompson, Christina M. Pabelick, Y. S. Prakash · 2013 · Expert Review of Respiratory Medicine
- Tau-induced neurodegeneration: mechanisms and targetsCindy Beharry, Leah S. Cohen, Jing Di, Kawsar Ibrahim, Susan Briffa-Mirabella, Alejandra del C. Alonso · 2014 · Neuroscience Bulletin
- SIMPLEmutations in Charcot-Marie-Tooth disease and the potential role of its protein product in protein degradationGulam Mustafa Saifi, Kinga Szigeti, Wojciech K. Wiszniewski, Michael E. Shy, Karen M. Krajewski, Irena Hausmanowa-Petrusewicz, Andrzej Kochański, Suzanne Reeser, Pedro Mancías, Ian J. Butler et al. · 2005 · Human Mutation
- Recessive axonal Charcot-Marie-Tooth disease due to compound heterozygous mitofusin 2 mutationsJames M. Polke, Matilde Laurá, Davide Pareyson, Franco Taroni, Micaela Milani, Giorgia Bergamin, V.S. Gibbons, Henry Houlden, S.C. Chamley, Julian C. Blake et al. · 2011 · Neurology
- Role of Mitochondria-Associated Endoplasmic Reticulum Membrane in Inflammation-Mediated Metabolic DiseasesThemis Thoudam, Jae‐Han Jeon, Chae‐Myeong Ha, In‐Kyu Lee · 2016 · Mediators of Inflammation
- GTP-Dependent Membrane FusionJames A. McNew, Holger Sondermann, Tina Lee, Mike Stern, Federica Brandizzí · 2013 · Annual Review of Cell and Developmental Biology
- Mitochondrial RetinopathiesMassimo Zeviani, Valério Carelli · 2021 · International Journal of Molecular Sciences
- Identification of the variant Ala335Val of MED25 as responsible for CMT2B2: molecular data, functional studies of the SH3 recognition motif and correlation between wild-type MED25 and PMP22 RNA levels in CMT1A animal modelsAlejandro Leal, Kathrin Huehne, Finn Bauer, Heinrich Sticht, Philipp Berger, Ueli Suter, Bernal Morera-Brenes, Gerardo Del Valle, James R. Lupski, Arif Bülent Ekici et al. · 2009 · Neurogenetics
- Mitochondrial remodeling: Rearranging, recycling, and reprogrammingRoberta A. Gottlieb, Daniel Bernstein · 2016 · Cell Calcium
- Treatment for Charcot-Marie-Tooth diseasePeter Young, Peter De Jonghe, Florian Stögbauer, Trude Butterfaß‐Bahloul · 2008 · Cochrane Database of Systematic Reviews
- Mitofusin 2 as a Driver That Controls Energy Metabolism and Insulin SignalingAntonio Zorzano A, María Isabel Hernández‐Álvarez, David Sebastián, Juan Pablo Muñoz · 2015 · Antioxidants and Redox Signaling
- Mitofusin 2 mutations affect mitochondrial function by mitochondrial DNA depletionStefan Vielhaber, Grażyna Dębska–Vielhaber, Viktoriya Peeva, Susanne Schöler, Alexei P. Kudin, Irina Minin, Stefanie Schreiber, Reinhard Dengler, Katja Kollewe, Werner Zuschratter et al. · 2012 · Acta Neuropathologica
- Mitochondrial function in vascular endothelial cell in diabetesMeenal Pangare, Ayako Makino · 2012 · Journal of Smooth Muscle Research
- Small heat shock protein 27 mutation in a Japanese patient with distal hereditary motor neuropathyKazuki Kijima, Chikahiko Numakura, Tomohide Goto, Takao Takahashi, Tesshu Otagiri, Kazuo Umetsu, Kiyoshi Hayasaka · 2005 · Journal of Human Genetics
- A Mutation of COX6A1 Causes a Recessive Axonal or Mixed Form of Charcot-Marie-Tooth DiseaseGen Tamiya, Satoshi Makino, Makiko Hayashi, Akiko Abe, Chikahiko Numakura, Masao Ueki, Atsushi Tanaka, Chizuru Ito, Kiyotaka Toshimori, Nobuhiro Ogawa et al. · 2014 · The American Journal of Human Genetics
- Mitochondrial lipids in neurodegenerationAndreas Aufschnaiter, Verena Kohler, Jutta Diessl, Carlotta Peselj, Didac Carmona‐Gutiérrez, Walter Keller, Sabrina Büttner · 2016 · Cell and Tissue Research
- Mitochondrial dismissal in mammals, from protein degradation to mitophagySilvia Campello, Flavie Strappazzon, Francesco Cecconi · 2013 · Biochimica et Biophysica Acta (BBA) - Bioenergetics
- Cofilin1-dependent actin dynamics control DRP1-mediated mitochondrial fissionKatharina Rehklau, Lena Hoffmann, Christine B. Gurniak, Martin Ott, Walter Witke, Luca Scorrano, Carsten Culmsee, Marco B. Rust · 2017 · Cell Death and Disease
- Mitofusins: Disease Gatekeepers and Hubs in Mitochondrial Quality Control by E3 LigasesMafalda Escobar‐Henriques, Mariana Joaquim · 2019 · Frontiers in Physiology
- Mitochondrial Dysfunction is a Converging Point of Multiple Pathological Pathways in Amyotrophic Lateral SclerosisPing Shi, Yanming Wei, Jia Yu Zhang, József Gál, Haining Zhu · 2010 · Journal of Alzheimer s Disease
- ALS/FTD-associated protein FUS induces mitochondrial dysfunction by preferentially sequestering respiratory chain complex mRNAsYueh-Lin Tsai, Tristan H. Coady, Lei Lü, Dinghai Zheng, Isabel Alland, Bin Tian, Neil A. Shneider, James L. Manley · 2020 · Genes & Development
- In vivo real-time dynamics of ATP and ROS production in axonal mitochondria show decoupling in mouse models of peripheral neuropathiesvan Hameren, Gerben, Campbell, Graham, Deck, Marie, Berthelot, Jade, Gautier, Benoit, Quintana, Patrice, Chrast, Roman, Tricaud, Nicolas · 2019 · Acta Neuropathologica Communications
- Therapeutic Approaches to Treat Mitochondrial Diseases: “One-Size-Fits-All” and “Precision Medicine” StrategiesEmanuela Bottani, Costanza Lamperti, Alessandro Prigione, Valeria Tiranti, Nicola Persico, Dario Brunetti · 2020 · Pharmaceutics
- Abnormal Mitochondrial Dynamics—A Novel Therapeutic Target for Alzheimer's Disease?Bo Su, Xinglong Wang, David Bonda, George L. Perry, Mark A. Smith, Xiongwei Zhu · 2010 · Molecular Neurobiology
- MIRO GTPases in Mitochondrial Transport, Homeostasis and PathologyBor Luen Tang · 2015 · Cells
- Overlapping molecular pathological themes link Charcot–Marie–Tooth neuropathies and hereditary spastic paraplegiasVincent Timmerman, Virginia E. Clowes, Evan Reid · 2012 · Experimental Neurology
- Mitofusin1 in oocyte is essential for female fertilityXiao-Jing Hou, Shuai Zhu, Hao Zhang, Chun-Ling Li, Danhong Qiu, Juan Ge, Xue-Jiang Guo, Qiang Wang · 2019 · Redox Biology
- Tying trafficking to fusion and fission at the mighty mitochondriaTrey Farmer, Naava Naslavsky, Steve Caplan · 2018 · Traffic
- Mitochondrial dynamics in the pathogenic mold Aspergillus fumigatus : therapeutic and evolutionary implicationsNeubauer, Michael, Zhu, Zhaojun, Penka, Mirjam, Helmschrott, Christoph, Wagener, Nikola, Wagener, Johannes · 2015 · Molecular Microbiology
- Two Close, Too CloseGerald W. Dorn, Luca Scorrano · 2010 · Circulation Research