A mutation creating a potential illegitimate microRNA target site in the myostatin gene affects muscularity in sheep

Fast folding and comparison of RNA secondary structures

Hofacker, I. L., Fontana, W., Stadler, P. F., Bonhoeffer, S., Tacker, M., & Schuster, P. M. (1994) · Monatshefte für Chemie - Chemical Monthly · doi:10.1007/bf00818163 · Cited by 2,314

Systematic discovery of regulatory motifs in human promoters and 3′ UTRs by comparison of several mammals

Xie, X., Lu, J., Kulbokas, E. J., Golub, T. R., Mootha, V., Lindblad-Toh, K., Lander, E. S., & Kellis, M. (2005) · Nature · doi:10.1038/nature03441 · Cited by 1,872

Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis

Zhao, Y. B., Samal, E., & Srivastava, D. P. (2005) · Nature · doi:10.1038/nature03817 · Cited by 1,572

Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAs

Bartel, D. P., & Chen, C. (2004) · Nature Reviews Genetics · doi:10.1038/nrg1328 · Cited by 1,439

Construction of multilocus genetic linkage maps in humans.

Lander, E. S., & Green, P. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.8.2363 · Cited by 1,426

Myostatin Mutation Associated with Gross Muscle Hypertrophy in a Child

Schuelke, M., Wagner, K. R., Stolz, L. E., Hübner, C., Riebel, T., Kömen, W., Braun, T., Tobin, J. F., & Lee, S.-J. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa040933 · Cited by 1,399

Ribo-gnome: The Big World of Small RNAs

Zamore, P. D., & Haley, B. (2005) · Science · doi:10.1126/science.1111444 · Cited by 1,289

Sequence Variants in SLITRK1 Are Associated with Tourette's Syndrome

Abelson, J. F., Kwan, K. Y., O'Roak, B. J., Baek, D. Y., Stillman, A. A., Morgan, T. M., Mathews, C. A., Pauls, D. L., Rašin, M.-R., Gunel, M., et al. (2005) · Science · doi:10.1126/science.1116502 · Cited by 940

Induction of Cachexia in Mice by Systemically Administered Myostatin

Zimmers, T. A., Davies, M. V., Koniaris, L. G., Haynes, P. A., Esquela‐Kerscher, A., Tomkinson, K. N., McPherron, A. C., Wolfman, N. M., & Lee, S. (2002) · Science · doi:10.1126/science.1069525 · Cited by 908

Mapping quantitative trait loci in crosses between outbred lines using least squares.

Haley, C., Knott, S., & Elsen, J. M. J. M. (1994) · Genetics · doi:10.1093/genetics/136.3.1195 · Cited by 699

Connecting Myokines and Metabolism

Ahima, R. S., & Park, H. K. (2015) · Endocrinology and Metabolism · doi:10.3803/enm.2015.30.3.235 · Cited by 111

MicroRNA-mediated regulation of gene expression is affected by disease-associated SNPs within the 3′-UTR via altered RNA structure

Haas, U., Sczakiel, G., & Laufer, S. (2012) · RNA Biology · doi:10.4161/rna.20497 · Cited by 109

Everything you wanted to know about small RNA but were afraid to ask

Boyd, S. D. (2008) · Laboratory Investigation · doi:10.1038/labinvest.2008.32 · Cited by 108

High concentrations of HGF inhibit skeletal muscle satellite cell proliferation in vitro by inducing expression of myostatin: a possible mechanism for reestablishing satellite cell quiescence in vivo

Yamada, M., Tatsumi, R., Yamanouchi, K., Hosoyama, T., SHIRATSUCHI, S., Satô, A., Mizunoya, W., Ikeuchi, Y., Furuse, M., & Allen, R. E. (2009) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00449.2009 · Cited by 113

Deciphering the genetic basis of animal domestication

Wiener, P., & Wilkinson, S. (2011) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2011.1376 · Cited by 113

Mirnas and Their Potential For Use Against Cancer and Other Diseases

Tili, E., Michaille, J., Gandhi, V. V., Plunkett, W. K., Sampath, D., & Calin, G. A. (2007) · Future Oncology · doi:10.2217/14796694.3.5.521 · Cited by 105

Role of microRNAs in skeletal muscle hypertrophy

Hitachi, K., & Tsuchida, K. (2014) · Frontiers in Physiology · doi:10.3389/fphys.2013.00408 · Cited by 106

RNA editing in regulating gene expression in the brain

Jepson, J. E. C., & Reenan, R. A. (2007) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2007.11.009 · Cited by 106

Function of microRNA‐375 and microRNA‐124a in pancreas and brain

Baroukh, N., & OBBERGHEN, E. V. (2009) · FEBS Journal · doi:10.1111/j.1742-4658.2009.07353.x · Cited by 105

Composite selection signals can localize the trait specific genomic regions in multi-breed populations of cattle and sheep

Randhawa, I. A. S., Khatkar, M. S., Thomson, P. C., & Raadsma, H. W. (2014) · BMC Genetics · doi:10.1186/1471-2156-15-34 · Cited by 105

Myostatin in the Pathophysiology of Skeletal Muscle

Bonnieu, A., Carnac, G., & Vernus, B. (2007) · Current Genomics · doi:10.2174/138920207783591672 · Cited by 113

miRNAs as biomarkers of myocardial infarction: a step forward towards personalized medicine?

Goretti, E., Wagner, D. R., & Devaux, Y. (2014) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2014.10.006 · Cited by 103

Multiplex gene editing via CRISPR/Cas9 exhibits desirable muscle hypertrophy without detectable off-target effects in sheep

Wang, X., Niu, Y., Zhou, J., Yu, H., Kou, Q., Lei, A., Zhao, X., Yan, H., Cai, B., Shen, Q., et al. (2016) · Scientific Reports · doi:10.1038/srep32271 · Cited by 106

The SNP c.1326T>G in the non-SMC condensin I complex, subunit G (NCAPG) gene encoding a p.Ile442Met variant is associated with an increase in body frame size at puberty in cattle

Setoguchi, K., Watanabe, T., Weikard, R., Albrecht, E., Kühn, C., Kinoshita, A., Sugimoto, Y., & Takasuga, A. (2011) · Animal Genetics · doi:10.1111/j.1365-2052.2011.02196.x · Cited by 103

Cryptic Patterning of Avian Skin Confers a Developmental Facility for Loss of Neck Feathering

Mou, C., Frédérique Pitel, A., Gourichon, D., Vignoles, F., Tzika, A. C., Tato, P., Yu, L., Burt, D. W., Bed’Hom, B., Tixier‐Boichard, M., et al. (2011) · PLoS Biology · doi:10.1371/journal.pbio.1001028 · Cited by 103

Two single nucleotide polymorphisms in the myostatin (GDF8) gene have significant association with muscle depth of commercial Charollais sheep

Hadjipavlou, G., Matika, O., Clop, A., & Bishop, S. C. (2008) · Animal Genetics · doi:10.1111/j.1365-2052.2008.01734.x · Cited by 103

Characterization of the complete porcine MSTN gene and expression levels in pig breeds differing in muscularity

Stinckens, A., Luyten, T., Bijttebier, J., den Maagdenberg, K. V., Dieltiens, D., Janssens, S., SMET, S. D., Georges, M., & Buys, N. (2008) · Animal Genetics · doi:10.1111/j.1365-2052.2008.01774.x · Cited by 109

Genome Editing of Pigs for Agriculture and Biomedicine

Yang, H., & Wu, Z. (2018) · Frontiers in Genetics · doi:10.3389/fgene.2018.00360 · Cited by 103

Generation and evaluation of Myostatin knock-out rabbits and goats using CRISPR/Cas9 system

Guo, R., Wan, Y., Xu, D., Cui, L., Deng, M., Zhang, G., Jia, R., Zhou, W., Wang, Z., Deng, K., et al. (2016) · Scientific Reports · doi:10.1038/srep29855 · Cited by 100

MicroRNA identity and abundance in porcine skeletal muscles determined by deep sequencing

Nielsen, M. M., Hansen, J., Hedegaard, J., Nielsen, R. O., Panitz, F., Bendixen, C., & Thomsen, B. (2009) · Animal Genetics · doi:10.1111/j.1365-2052.2009.01981.x · Cited by 97

Selective inhibition of microRNA accessibility by RBM38 is required for p53 activity

Léveillé, N., Elkon, R., Dávalos, V., Manoharan, V., Hollingworth, D., Vrielink, J. A. F. O., le Sage, C., Melo, C. A., Horlings, H. M., Wesseling, J., et al. (2011) · Nature Communications · doi:10.1038/ncomms1519 · Cited by 101

Congenital Heart Disease: The Crossroads of Genetics, Epigenetics and Environment

Vecoli, C., Pulignani, S., Foffa, I., & Andreassi, M. G. (2014) · Current Genomics · doi:10.2174/1389202915666140716175634 · Cited by 102

The Domestication Makeup: Evolution, Survival, and Challenges

Ahmad, H. I., Ahmad, M. J., Jabbir, F., Ahmar, S., Ahmad, N., Elokil, A. A., & Chen, J. (2020) · Frontiers in Ecology and Evolution · doi:10.3389/fevo.2020.00103 · Cited by 98

Overexpression of follistatin in trout stimulates increased muscling

Medeiros, E. F., Phelps, M., Fuentes, F. D., & Bradley, T. M. (2009) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.91020.2008 · Cited by 99

CRISPR/Cas9-mediated knockout of myostatin in Chinese indigenous Erhualian pigs

Wang, K., Tang, X., Xie, Z., Zou, X., Li, M., Yuan, H., Guo, N., Ouyang, H., Jiao, H., & Pang, D. (2017) · Transgenic Research · doi:10.1007/s11248-017-0044-z · Cited by 97

Myostatin Up-Regulation Is Associated with the Skeletal Muscle Response to Hypoxic Stimuli

Hayot, M., Rodriguez, J., Vernus, B., Carnac, G., Jean, E., Allen, D., Goret, L., Obert, P., Candau, R., & Bonnieu, A. (2011) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2010.09.008 · Cited by 98

Peripheral myelin protein 22 is regulated post‐transcriptionally by miRNA‐29a

Verrier, J. D., Lau, P., Hudson, L. D., Murashov, A. K., Renne, R., & Notterpek, L. M. (2009) · Glia · doi:10.1002/glia.20846 · Cited by 96

Chapter 13 Long‐Range Gene Control and Genetic Disease

Kleinjan, D. A., & Lettice, L. A. (2008) · Advances in genetics · doi:10.1016/s0065-2660(07)00013-2 · Cited by 97

MicroRNA-7 Inhibits Tumor Metastasis and Reverses Epithelial-Mesenchymal Transition through AKT/ERK1/2 Inactivation by Targeting EGFR in Epithelial Ovarian Cancer

Zhou, X., Hu, Y., Dai, L., Wang, Y., Zhou, J., Wang, W., Di, W. J., & Qiu, L. (2014) · PLoS ONE · doi:10.1371/journal.pone.0096718 · Cited by 93

SNPing cancer in the bud: MicroRNA and microRNA-target site polymorphisms as diagnostic and prognostic biomarkers in cancer

Salzman, D. W., & Weidhaas, J. B. (2012) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2012.08.016 · Cited by 93

A global view of porcine transcriptome in three tissues from a full-sib pair with extreme phenotypes in growth and fat deposition by paired-end RNA sequencing

Chen, C., Ai, H., Ren, J., Li, W., Li, P., Qiao, R., Ouyang, J., Yang, M. Y., Ma, J., & Huang, L. (2011) · BMC Genomics · doi:10.1186/1471-2164-12-448 · Cited by 96

Characterization of an extensive rainbow trout miRNA transcriptome by next generation sequencing

Juanchich, A., Bardou, P., Rué, O., Gabillard, J., Gaspin, C., Bobe, J., & Guiguen, Y. (2016) · BMC Genomics · doi:10.1186/s12864-016-2505-9 · Cited by 93

Targeting the myostatin signaling pathway to treat muscle wasting diseases

Han, H. Q., & Mitch, W. E. (2011) · Current Opinion in Supportive and Palliative Care · doi:10.1097/spc.0b013e32834bddf9 · Cited by 96

Article Commentary: The Genetic Architecture of Domestication in Animals

Wright, D. (2015) · Bioinformatics and Biology Insights · doi:10.4137/bbi.s28902 · Cited by 92

CRISPR/Cas9-mediated myostatin disruption enhances muscle mass in the olive flounder Paralichthys olivaceus

Kim, J., Cho, J. Y., Kim, J.-W., Kim, H., Noh, J. K., Kim, Y., Hwang, H.-K., Kim, W., Yeo, S., An, C. M., et al. (2019) · Aquaculture · doi:10.1016/j.aquaculture.2019.734336 · Cited by 91

Myostatin regulates glucose metabolism via the AMP-activated protein kinase pathway in skeletal muscle cells

Chen, Y., Ye, J., Cao, L., Zhang, Y., Xia, W., & Zhu, D. (2010) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2010.09.017 · Cited by 91

A variant affecting a putative miRNA target site in estrogen receptor (ESR) 1 is associated with breast cancer risk in premenopausal women

Tchatchou, S., Jung, A., Hemminki, K., Sutter, C., Wappenschmidt, B., Bugert, P., Weber, B. H. F., Niederacher, D., Arnold, N., Varon-Mateeva, R., et al. (2008) · Carcinogenesis · doi:10.1093/carcin/bgn253 · Cited by 89

microRNAs in skeletal muscle differentiation and disease

Goljanek‐Whysall, K., Sweetman, D., & Münsterberg, A. (2012) · Clinical Science · doi:10.1042/cs20110634 · Cited by 89

Microarray-Based Approach Identifies Differentially Expressed MicroRNAs in Porcine Sexually Immature and Mature Testes

Luo, L., Ye, L., Liu, G., Shao, G., Zheng, R., Ren, Z., Zuo, B., Xu, D., Lei, M., Jiang, S., et al. (2010) · PLoS ONE · doi:10.1371/journal.pone.0011744 · Cited by 90

Proteolysis in illness-associated skeletal muscle atrophy: from pathways to networks

Wing, S. S., Lecker, S. H., & Jagoe, R. T. (2011) · Critical Reviews in Clinical Laboratory Sciences · doi:10.3109/10408363.2011.586171 · Cited by 93

Hydrodynamic Limb Vein Injection of Adeno-Associated Virus Serotype 8 Vector Carrying Canine Myostatin Propeptide Gene into Normal Dogs Enhances Muscle Growth

Qiao, C., Li, J., Zheng, H., Bogan, J. R., Li, J., Yuan, Z., Zhang, C., Bogan, D., Kornegay, J. N., & Xiao, X. (2009) · Human Gene Therapy · doi:10.1089/hum.2008.135 · Cited by 93

Sequence Variation of MicroRNAs and Their Binding Sites in Arabidopsis

Ehrenreich, I. M., & Purugganan, M. D. (2008) · PLANT PHYSIOLOGY · doi:10.1104/pp.108.116582 · Cited by 89

A Missense Mutation in PPARD Causes a Major QTL Effect on Ear Size in Pigs

Ren, J., Duan, Y., Qiao, R., Yao, F., Zhang, Z., Yang, B. J., Guo, Y., Xiao, S., Wei, R., Ouyang, Z., et al. (2011) · PLoS Genetics · doi:10.1371/journal.pgen.1002043 · Cited by 88

MicroRNA dysregulation as a prognostic biomarker in colorectal cancer

Ng, S. S., Dong, Y., & Yu, J. Q. (2014) · Cancer Management and Research · doi:10.2147/cmar.s35164 · Cited by 88

microRNA control of cell-cell signaling during development and disease

Hagen, J. W., & Lai, E. C. (2008) · Cell Cycle · doi:10.4161/cc.6447 · Cited by 88

Extracellular Regulation of Myostatin: A Molecular Rheostat for Muscle Mass

Lee, S. (2010) · Immunology Endocrine & Metabolic Agents - Medicinal Chemistry · doi:10.2174/187152210793663748 · Cited by 88

Plasma MicroRNA Levels Differ between Endurance and Strength Athletes

Wardle, S. L., Bailey, M. E. S., Kilikevičius, A., Malkova, D., Wilson, R. H., Venckūnas, T., & Moran, C. N. (2015) · PLoS ONE · doi:10.1371/journal.pone.0122107 · Cited by 86

Mega roles of microRNAs in regulation of skeletal muscle health and disease

Sharma, M. (2014) · Frontiers in Physiology · doi:10.3389/fphys.2014.00239 · Cited by 89

Myostatin Inhibitors: Panacea or Predicament for Musculoskeletal Disorders?

Suh, J., & Lee, Y. (2020) · Journal of Bone Metabolism · doi:10.11005/jbm.2020.27.3.151 · Cited by 92

Proteomic analysis of ovine muscle hypertrophy1

Hamelin, M., Sayd, T., Chambon, C., Bouix, J., Bibé, B. B., Milenković, D., Levéziel, H. H., Georges, M., Clop, A., Marinova, P., et al. (2006) · Journal of Animal Science · doi:10.2527/jas.2006-162 · Cited by 86

MicroRNA and cardiac pathologies

Latronico, M. V. G., Catalucci, D., & Condorelli, G. (2008) · Physiological Genomics · doi:10.1152/physiolgenomics.90254.2008 · Cited by 86

Genetics of the phenotypic evolution in sheep: a molecular look at diversity-driving genes

Kalds, P., Zhou, S., Gao, Y., Cai, B., Huang, S., Chen, Y., & Wang, X. (2022) · Genetics Selection Evolution · doi:10.1186/s12711-022-00753-3 · Cited by 85

MicroRNAs as major regulators of the autophagy pathway

Akkoç, Y., & Gözüaçık, D. (2020) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2020.118662 · Cited by 87

Myostatin: a skeletal muscle chalone

Lee, S.-J. (2023) · Annual Review of Physiology · doi:10.1146/annurev-physiol-012422-112116 · Cited by 84

A critical analysis of production-associated DNA polymorphisms in the genes of cattle, goat, sheep, and pig

Ibeagha-Awemu, E. M., Kgwatalala, P. M., & Zhao, X. (2008) · Mammalian Genome · doi:10.1007/s00335-008-9141-x · Cited by 84

MicroRNA-146a and Ets-1 gene polymorphisms in ocular Behçet's disease and Vogt–Koyanagi–Harada syndrome

Zhou, Q., Hou, S., Liang, L., Li, X., Tan, X., Wei, L., Lei, B., Kijlstra, A., & Yang, P. (2012) · Annals of the Rheumatic Diseases · doi:10.1136/annrheumdis-2012-201627 · Cited by 84

A systems biology approach using metabolomic data reveals genes and pathways interacting to modulate divergent growth in cattle

Widmann, P., Reverter, A., Fortes, M. R. S., Weikard, R., Suhre, K., Hammon, H. M., Albrecht, E., & Kuehn, C. (2013) · BMC Genomics · doi:10.1186/1471-2164-14-798 · Cited by 83

Functional genetic variation of human miRNAs and phenotypic consequences

Borel, C., & Antonarakis, S. E. (2008) · Mammalian Genome · doi:10.1007/s00335-008-9137-6 · Cited by 83

Inhibition of myostatin and related signaling pathways for the treatment of muscle atrophy in motor neuron diseases

Abati, E., Manini, A., Comi, G. P., & Corti, S. P. (2022) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-022-04408-w · Cited by 85

Prediction and Verification of miRNA Expression in Human and Rat Retinas

Arora, A., McKay, G. J., & Simpson, D. A. C. (2007) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.06-1221 · Cited by 83

GDF11 promotes osteogenesis as opposed to MSTN, and follistatin, a MSTN/GDF11 inhibitor, increases muscle mass but weakens bone

Suh, J., Kim, N.-K., Lee, S., Eom, J., Lee, Y., Park, J., Woo, K. M., Baek, J., Kim, J., Ryoo, H., et al. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1916034117 · Cited by 87

AAV-mediated delivery of a mutated myostatin propeptide ameliorates calpain 3 but not α-sarcoglycan deficiency

Bartoli, M., Poupiot, J., Vulin, A., Fougerousse, F., Arandel, L., Danièle, N., Roudaut, C., Noulet, F., Garcı́a, L., Danos, O., et al. (2007) · Gene Therapy · doi:10.1038/sj.gt.3302928 · Cited by 85

miR-206 Represses Hypertrophy of Myogenic Cells but Not Muscle Fibers via Inhibition of HDAC4

Winbanks, C. E., Beyer, C., Hagg, A., Qian, H., Sepulveda, P. V., & Gregorevic, P. (2013) · PLoS ONE · doi:10.1371/journal.pone.0073589 · Cited by 83

Potential Use of Gene Transfer in Athletic Performance Enhancement

Baoutina, A., Alexander, I. E., Rasko, J. E. J., & Emslie, K. R. (2007) · Molecular Therapy · doi:10.1038/sj.mt.6300278 · Cited by 84

Molecular, cellular and physiological investigation of myostatin propeptide-mediated muscle growth in adult mice

Matsakas, A., Foster, K., Otto, A., Macharia, R., Elashry, M. I., Feist, S. A., Graham, I. R., Foster, H., Yaworsky, P. J., Walsh, F. S., et al. (2009) · Neuromuscular Disorders · doi:10.1016/j.nmd.2009.06.367 · Cited by 84

Combination of Myostatin Pathway Interference and Dystrophin Rescue Enhances Tetanic and Specific Force in Dystrophic mdx Mice

Dumonceaux, J., Marie, S., Beley, C., Trollet, C., Vignaud, A., Ferry, A., Butler-Browne, G. S., & Garcı́a, L. (2010) · Molecular Therapy · doi:10.1038/mt.2009.322 · Cited by 81

CRISPR /Cas9‐mediated MSTN disruption and heritable mutagenesis in goats causes increased body mass

Wang, X., Niu, Y., Zhou, J., Zhu, H., Ma, B., Yu, H., Yan, H., Hua, J., Huang, X., Qu, L., et al. (2018) · Animal Genetics · doi:10.1111/age.12626 · Cited by 80

Drug development progress in duchenne muscular dystrophy

Deng, J., Zhang, J., Shi, K., & Liu, Z. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.950651 · Cited by 78

The Expanding Universe of Noncoding RNAsPreprint

Hannon, G. J., Rivas, F. V., Murchison, E. P., & STEITZ, J. A. (2006) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.2006.71.064 · Cited by 80

Does regulation of skeletal muscle function involve circulating microRNAs?

Aoi, W., & Sakuma, K. (2014) · Frontiers in Physiology · doi:10.3389/fphys.2014.00039 · Cited by 80

Identification and comparative analysis of the Eriocheir sinensis microRNA transcriptome response to Spiroplasma eriocheiris infection using a deep sequencing approach

Ou, J., Meng, Q., Li, Y., Xiu, Y., Du, J., Gu, W., Wu, T., Li, W., Ding, Z., & Wang, W. (2011) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2011.11.027 · Cited by 77

Genomics to accelerate genetic improvement in tilapia

Yañez, J. M., Joshi, R., & Yoshida, G. (2020) · Animal Genetics · doi:10.1111/age.12989 · Cited by 79

MicroRNAs as Biomarkers for Animal Health and Welfare in Livestock

Miretti, S., Lecchi, C., Ceciliani, F., & Baratta, M. (2020) · Frontiers in Veterinary Science · doi:10.3389/fvets.2020.578193 · Cited by 77

Cell Types Used for Cultured Meat Production and the Importance of Myokines

Shaikh, S., Lee, E. J., Ahmad, K., Ahmad, S. S., Chun, H.-J., Lim, J. H., Lee, Y., & Choi, I. (2021) · Foods · doi:10.3390/foods10102318 · Cited by 81

The long and short of inverted repeat genes in animals: MicroRNAs, mirtrons and hairpin RNAs

Okamura, K., Chung, W., & Lai, E. C. (2008) · Cell Cycle · doi:10.4161/cc.7.18.6734 · Cited by 79

Inhibition of myostatin does not ameliorate disease features of severe spinal muscular atrophy mice

Sumner, C. J., Wee, C. D., Warsing, L. C., Choe, D. W., Ng, A. S., Lutz, C. M., & Wagner, K. R. (2009) · Human Molecular Genetics · doi:10.1093/hmg/ddp253 · Cited by 78

Discovery and characterization of miRNA genes in atlantic salmon (Salmo salar) by use of a deep sequencing approach

Andreassen, R., Worren, M. M., & Høyheim, B. (2013) · BMC Genomics · doi:10.1186/1471-2164-14-482 · Cited by 75

Effect of myostatin F94L on carcass yield in cattle

Sellick, G. S., Pitchford, W. S., Morris, C. A., Cullen, N. G., Crawford, A. M., Raadsma, H. W., & Bottema, C. D. K. (2007) · Animal Genetics · doi:10.1111/j.1365-2052.2007.01623.x · Cited by 75

BOARD-INVITED REVIEW: Applications of genomic information in livestock1

Sellner, E. M., Kim, J. W., McClure, M. C., Taylor, K. H., Schnabel, R. D., & Taylor, J. F. (2007) · Journal of Animal Science · doi:10.2527/jas.2007-0291 · Cited by 74

Impact of two myostatin (MSTN) mutations on weight gain and lamb carcass classification in Norwegian White Sheep (Ovis aries)

Boman, I. A., Klemetsdal, G., Nafstad, O., Blichfeldt, T., & Våge, D. I. (2010) · Genetics Selection Evolution · doi:10.1186/1297-9686-42-4 · Cited by 75

Single Nucleotide Polymorphisms in the Insulin-Like Growth Factor 1 (IGF-1) Gene are Associated with Performance in Holstein-Friesian Dairy Cattle

Mullen, M. P., Berry, D. P., Howard, D. J., Diskin, M. G., Lynch, C. O., Giblin, L., Kenny, D. A., Magee, D. A., Meade, K. G., & Waters, S. M. (2011) · Frontiers in Genetics · doi:10.3389/fgene.2011.00003 · Cited by 77

A MicroRNA Repertoire for Functional Genome Research in Rainbow Trout (Oncorhynchus mykiss)

Salem, M., Xiao, C., Womack, J., Rexroad, C. E., & Yao, J. (2009) · Marine Biotechnology · doi:10.1007/s10126-009-9232-z · Cited by 75

Negative Auto-Regulation of Myostatin Expression is Mediated by Smad3 and MicroRNA-27

McFarlane, C., Vajjala, A., Harikumar, A., Lokireddy, S., Ge, X., Bonala, S., Manickam, R., Kambadur, R., & Sharma, M. (2014) · PLoS ONE · doi:10.1371/journal.pone.0087687 · Cited by 74

Myostatin blockade improves function but not histopathology in a murine model of limb‐girdle muscular dystrophy 2C

Bogdanovich, S., McNally, E. M., & Khurana, T. S. (2007) · Muscle & Nerve · doi:10.1002/mus.20920 · Cited by 77

A review of the genetic and epigenetic factors affecting lamb survival

Brien, F. D., Cloete, S. W. P., Fogarty, N. M., Greeff, J. C., Hebart, M. L., Hiendleder, S., Edwards, J. E. H., Kelly, J. M., Kind, K. L., Kleemann, D. O., et al. (2014) · Animal Production Science · doi:10.1071/an13140 · Cited by 77

The role of microRNA-1 and microRNA-206 in the proliferation and differentiation of bovine skeletal muscle satellite cells

Dai, Y., Wang, Y. M., Zhang, W. R., Liu, X. F., Li, X., Ding, X. B., & Guo, H. (2015) · In Vitro Cellular & Developmental Biology - Animal · doi:10.1007/s11626-015-9953-4 · Cited by 75

MicroRNAs in carcinogenesis

Hagan, J. P., & Croce, C. M. (2007) · Cytogenetic and Genome Research · doi:10.1159/000108308 · Cited by 74

Evolution of MicroRNAs and the Diversification of Species

Loh, Y. E., Yi, S. V., & Streelman, J. T. (2010) · Genome Biology and Evolution · doi:10.1093/gbe/evq085 · Cited by 72

miRNA, Development and Disease

Amiel, J., de Pontual, L., & Henrion‐Caude, A. (2012) · Advances in genetics · doi:10.1016/b978-0-12-404742-6.00001-6 · Cited by 73

Evolution of flower color pattern through selection on regulatory small RNAs

Bradley, D. J., Xu, P., Mohorianu, I. I., Whibley, A. C., Field, D. L., Tavares, H., Couchman, M., Copsey, L., Carpenter, R., Li, M., et al. (2017) · Science · doi:10.1126/science.aao3526 · Cited by 68

Molecular therapy in the microRNA era

Würdinger, T., & Costa, F. F. (2006) · The Pharmacogenomics Journal · doi:10.1038/sj.tpj.6500429 · Cited by 71

Cellular mechanisms and local progenitor activation to regulate skeletal muscle mass

Cassano, M., Quattrocelli, M., Crippa, S., Perini, I., Ronzoni, F., & Sampaolesi, M. (2009) · Journal of Muscle Research and Cell Motility · doi:10.1007/s10974-010-9204-y · Cited by 70

Role and therapeutic potential of microRNAs in diabetes

Kolfschoten, I., Roggli, E., Nesca, V., & Regazzi, R. (2009) · Diabetes Obesity and Metabolism · doi:10.1111/j.1463-1326.2009.01118.x · Cited by 71

Heart failure: advances through genomics

Creemers, E. E., Wilde, A. A. M., & Pinto, Y. M. (2011) · Nature Reviews Genetics · doi:10.1038/nrg2983 · Cited by 69

Molecular and cell-based therapies for muscle degenerations: a road under construction

Berardi, E., Annibali, D., Cassano, M., Crippa, S., & Sampaolesi, M. (2014) · Frontiers in Physiology · doi:10.3389/fphys.2014.00119 · Cited by 69

miR-421 and miR-30c Inhibit SERPINE 1 Gene Expression in Human Endothelial Cells

Marchand, A., Proust, C., Morange, P., Lompré, A., & Trégouët, D. (2012) · PLoS ONE · doi:10.1371/journal.pone.0044532 · Cited by 69

MicroRNA in cell differentiation and development

Shi, Y., & Jin, Y. (2009) · Science in China Series C Life Sciences · doi:10.1007/s11427-009-0040-5 · Cited by 69

Investigations into the GDF8 g+6723G-A polymorphism in New Zealand Texel sheep1

Johnson, P. L., Dodds, K. G., Bain, W. E., Greer, G. J., McLean, N. J., McLaren, R. J., Galloway, S., van Stijn, T. C., & McEwan, J. C. (2009) · Journal of Animal Science · doi:10.2527/jas.2008-1508 · Cited by 68

Generation of cloned adult muscular pigs with myostatin gene mutation by genetic engineering

Kang, J., Kim, S., Zhu, H., Jin, L. G., Guo, Q., Li, X., Zhang, Y., Xing, X., Xuan, M., Zhang, G.-L., et al. (2017) · RSC Advances · doi:10.1039/c6ra28579a · Cited by 69

Myostatin: Basic biology to clinical application

Esposito, P. B., Picciotto, D., Battaglia, Y., Costigliolo, F., Viazzi, F. C., & Verzola, D. (2022) · Advances in clinical chemistry · doi:10.1016/bs.acc.2021.09.006 · Cited by 72

Mighty Meaty miRNAs

(2006) · Science · doi:10.1126/science.312.5780.1574d

A lean feat — microRNAs and muscle mass

Skipper, M. (2006) · Nature Reviews Genetics · doi:10.1038/nrg1898 · Cited by 1

Polymorphic Polymorphic MicroRNA-Target Interactions: A Novel Source of Phenotypic VariationPreprint

Georges, M., Clop, A., Marcq, F., Takeda, H., Pirottin, D., Hiard, S., Tordoir, X., Caiment, F., Meish, F., Bibé, B. B., et al. (2006) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.2006.71.056 · Cited by 52

A QTL with Major Effect on Muscularity Maps

(2014)

The origin of the double-muscle mutation in the MSTN gene of sheep and its effects on growth traits in the Hu × East Friesian hybrid population

Xu, Y., Gao, C., Wang, H. E., Cao, C., Zhang, X., Sun, B., Liang, Y., Bai, Y., Li, Y., Jiang, Y., et al. (2026) · Frontiers in Veterinary Science · doi:10.3389/fvets.2026.1791780 · Cited by 1