Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer
Schlesinger, Yeshayahu, Straussman, Ravid, Keshet, Ilana, Farkash, Shlomit, Hecht, Merav, Zimmerman, Joseph, Eden, Eran, Yakhini, Zohar +5 more·2007·Nature Genetics
DOI 10.1038/ng1950
Cited by (1,000)
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- Lsh controls Hox gene silencing during developmentSichuan Xi, Heming Zhu, Hong Xu, Anja Schmidtmann, Theresa M. Geiman, Kathrin Muegge · 2007 · Proceedings of the National Academy of Sciences
- Methylation analyses in liquid biopsyDelphine Lissa, Ana I. Robles · 2016 · Translational Lung Cancer Research
- Role of polycomb proteins Ring1A and Ring1Bin the epigenetic regulation of gene expressionMiguel Vidal · 2009 · The International Journal of Developmental Biology
- Histone Modification Therapy of CancerChiara Biancotto, Gianmaria Frigè, Saverio Minucci · 2010 · Advances in genetics