Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer

Schlesinger, Yeshayahu, Straussman, Ravid, Keshet, Ilana, Farkash, Shlomit, Hecht, Merav, Zimmerman, Joseph, Eden, Eran, Yakhini, Zohar +5 more·2007·Nature Genetics

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  17. DNA methylation in development and human disease
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    Weisenberger, Daniel J. · 2014 · Journal of Clinical Investigation
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    C. Bock, T. Lengauer · 2008 · Bioinform.
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    M. Widschwendter, Allison Jones, I. Evans, D. Reisel, J. Dillner, K. Sundström, E. Steyerberg, Y. Vergouwe, O. Wegwarth, F. G. Rebitschek et al. · 2018 · Nature Reviews Clinical Oncology
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  95. DNA methylation biomarkers for lung cancer
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    Gennadi V. Glinsky · 2008 · Journal of Clinical Oncology
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