The AIM2 inflammasome is critical for innate immunity to Francisella tularensis

Pathogen Recognition and Innate Immunity

Akira, S., Uematsu, S., & Takeuchi, O. (2006) · Cell · doi:10.1016/j.cell.2006.02.015 · Cited by 11,976

Cutting Edge: NF-κB Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression

Bauernfeind, F. G., Horvath, G. L., Stutz, A., Alnemri, E. S., MacDonald, K. L., Speert, D. P., Fernandes‐Alnemri, T., Wu, J., Monks, B. G., Fitzgerald, K. A., et al. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0901363 · Cited by 3,087

Cryopyrin activates the inflammasome in response to toxins and ATP

Mariathasan, S., Weiss, D. S., Newton, K., McBride, J., O'Rourke, K., Roose-Girma, M., Lee, W. P., Weinrauch, Y., Monack, D. M., & Dixit, V. M. (2006) · Nature · doi:10.1038/nature04515 · Cited by 3,080

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

Hornung, V., Bauernfeind, F., Halle, A., Samstad, E. O., Kono, H., Rock, K. L., Fitzgerald, K. A., & Latz, E. (2008) · Nature Immunology · doi:10.1038/ni.1631 · Cited by 3,065

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

Hornung, V., Ablasser, A., Charrel-Dennis, M., Bauernfeind, F., Horvath, G., Caffrey, D. R., Latz, E., & Fitzgerald, K. A. (2009) · Nature · doi:10.1038/nature07725 · Cited by 2,627

The NALP3 inflammasome is involved in the innate immune response to amyloid-β

Halle, A., Hornung, V., Petzold, G. C., Stewart, C. R., Monks, B. G., Reinheckel, T., Fitzgerald, K. A., Latz, E., Moore, K. J., & Golenbock, D. T. (2008) · Nature Immunology · doi:10.1038/ni.1636 · Cited by 2,441

The Inflammasomes: Guardians of the Body

Martinon, F., Mayor, A., & Tschopp, J. (2009) · Annual Review of Immunology · doi:10.1146/annurev.immunol.021908.132715 · Cited by 2,436

Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

Mariathasan, S., Newton, K., Monack, D. M., Vucic, D., French, D. M., Lee, W. P., Roose-Girma, M., Erickson, S. L., & Dixit, V. M. (2004) · Nature · doi:10.1038/nature02664 · Cited by 1,864

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

Fernandes-Alnemri, T., Yu, J.-W., Datta, P., Wu, J., & Alnemri, E. S. (2009) · Nature · doi:10.1038/nature07710 · Cited by 1,831

Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1β in salmonella-infected macrophages

Franchi, L., Amer, A., Body-Malapel, M., Kanneganti, T.-D., Özören, N., Jagirdar, R., Inohara, N., Vandenabeele, P., Bertin, J., Coyle, A., et al. (2006) · Nature Immunology · doi:10.1038/ni1346 · Cited by 1,131

Convergence of host immune mechanisms in Mycobacterium tuberculosis pathogenesis

Chandra, R. (2014) · InTech eBooks · doi:10.5772/58319 · Cited by 2

A new cytosolic DNA-recognition pathway for DNA-induced inflammatory responses

Meng, J., Liu, X., & Cao, X. (2014) · Cellular and Molecular Immunology · doi:10.1038/cmi.2014.57 · Cited by 3

Inflammasomes in Myeloid Cells: Warriors Within

Jha, S., Brickey, W. J., & Ting, J. P.-Y. (2017) · ASM Press eBooks · doi:10.1128/9781555819194.ch17 · Cited by 3

Mouse guanylate-binding proteins of the chromosome 3 cluster do not mediate antiviral activity in vitro or in mouse models of infection

Tessema, M. B., Feng, S., Tuipulotu, D. E., Farrukee, R., Ngo, C., de Graça, C. G., Yamomoto, M., Utzschneider, D. T., Brööks, A. G., Londrigan, S. L., et al. (2024) · Communications Biology · doi:10.1038/s42003-024-06748-8 · Cited by 3

Host DNA Induced Inflammation and Autoimmune Diseases

Pandey, S., & Kawai, T. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-404732-7.00005-8 · Cited by 3

Acetylcholine and an acetylcholinesterase inhibitor neostigmine can aggravate tularemia progress in BALB/c mice

Pohanka, M., Pavliš, O., Svobodova, H., & Pikula, J. (2012) · Interdisciplinary Toxicology · doi:10.2478/v10102-012-0004-7 · Cited by 3

Review Article. Absent in melanoma 2 (AIM2) in the intestine: diverging actions with converging consequences

Vanhove, W., Peeters, P. M., Cleynen, I., Assche, G. V., Ferrante, M., Vermeire, S., & Arijs, I. (2017) · Inflammasome · doi:10.1515/infl-2017-0001 · Cited by 5

Integrative Transcriptomic Profiling Identifies TNF and IL1B as Candidate Key Early-Response Genes in Macrophages Infected with Smooth Brucella Using a Comprehensive Bioinformatic Approach

Yang, X., & Chen, Q. (2025) · Biology · doi:10.3390/biology14050579 · Cited by 2

Type I interferons in bacterial diseases: myeloid cells at the crossroads of protection and pathology

Lyadova, I. V. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1717370 · Cited by 2

dsDNA-Induced AIM2 Pyroptosis in Glomerular Endothelial Cells Aggravate Lupus Nephritis

Zhang, J., Quan, S., Huang, R., Zeng, J., Yang, B., Liao, P., & Li, X. (2026) · Cell Biochemistry and Biophysics · doi:10.1007/s12013-026-02001-7 · Cited by 2

Herpes simplex virus 1 harboring poly(T) DNA sequences as a key ligand for AIM2 inflammasome activation and host defense

Oh, S., Oh, J., Im, K., Kim, T. H., Lee, J., Shin, K., Nabukenya, M., Seok, C., Park, J., Yu, G., et al. (2026) · Nature Communications · doi:10.1038/s41467-026-71896-w · Cited by 2

The lysosome as a central executioner: orchestrating multiple modalities of programmed cell death

Yang, H., Ren, W., & Cai, Z. (2026) · Frontiers in Cell Death · doi:10.3389/fceld.2026.1841940 · Cited by 2

Modified activities of macrophages’ deubiquitinating enzymes after Francisella infection

Vozandychova, V., Řehulka, P., Hercík, K., Špidlová, P., Pavlik, P., Hanuš, J., Hadravová, R., & Stulík, J. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1252827 · Cited by 2

TolC and EmrA1 contribute to Francisella novicida multidrug resistance and modulation of host cell death

Kopping, E. J., Benziger, P. T., & Thanassi, D. G. (2024) · Journal of Bacteriology · doi:10.1128/jb.00246-24 · Cited by 2

A novel method of Francisella infection of epithelial cells using HeLa cells expressing fc gamma receptor

Nakamura, T., Shimizu, T., Nishinakama, N., Takahashi, R., Arasaki, K., Uda, A., Watanabe, K., & Watarai, M. (2024) · BMC Infectious Diseases · doi:10.1186/s12879-024-10083-y · Cited by 2

Insights into ubiquitinome dynamics in the host‒pathogen interplay during Francisella novicida infection

Yang, L., Li, Y., Xie, Q., Xu, T., & Qi, X. (2024) · Cell Communication and Signaling · doi:10.1186/s12964-024-01887-1 · Cited by 2

Evolutionary Divergence in Human Versus Mouse Innate Immune Gene Regulation and Function

Kapétanovic, R., Ariffin, J. K., & Sweet, M. J. (2014) · Springer eBooks · doi:10.1007/978-3-319-07623-2_6 · Cited by 2

Ready, AIM, fire!

Bird, L. (2010) · Nature reviews. Immunology · doi:10.1038/nri2771 · Cited by 2

A study of innate immune kinetics reveals a role for a chloride transporter in a virulent Francisella tularensis type B strain

Matz, L. M., & Petrosino, J. F. (2021) · MicrobiologyOpen · doi:10.1002/mbo3.1170 · Cited by 2

Correlation between double‐stranded DNA and acute urticaria

Li, Y., Li, Z., Lu, J., Qu, G., Qin, Q., Zhang, C., Bai, Y., Wang, D., Luo, S., Li, B., et al. (2024) · International Journal of Dermatology · doi:10.1111/ijd.17086 · Cited by 2

Pervasive loss of regulated necrotic cell death genes in elephants, hyraxes, and sea cows ( Paenungualta )Preprint

Birkemeier, M., Swindle, A., Bowman, J. D., & Lynch, V. J. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.04.04.588129 · Cited by 2

Ifi204/p204, a new piece in the sepsis puzzle

Subramanian, G., Chakravarti, R., & Chattopadhyay, S. (2018) · Annals of Translational Medicine · doi:10.21037/atm.2018.09.22 · Cited by 1

Characterization of Inflammasomes and Their Regulation in the Red Fox

Ahn, H., Jeong, D., Lee, G., Lee, S., Yang, J.-J., Kim, Y., Hahn, T., Choi, S., & Lee, G. (2023) · Animals · doi:10.3390/ani13243842 · Cited by 1

Inflammasome activation in response to aberrations of cellular homeostasis in epithelial cells from human cornea and retina

Korhonen, E. (2024) · Acta Ophthalmologica · doi:10.1111/aos.16646 · Cited by 2

DNA-RNA hybrids in inflammation: sources, immune response, and therapeutic implications

Chen, L., Hu, L., Han, C., Mao, J., Ye, M., & Jin, X. (2025) · Journal of Molecular Medicine · doi:10.1007/s00109-025-02533-0 · Cited by 1

LncRNAs in inflammasome regulation: Orchestrating cancer signaling and chemoresistance

Mukhlif, M. Y., Mahmood, S. H., Khalaf, A. A., Sanghvi, G. V., Ballal, S., Singh, A., Sabarivani, A., Mishra, S. S., Mustafa, Y. F., & Yasin, H. A. (2025) · Seminars in Oncology · doi:10.1016/j.seminoncol.2025.152455 · Cited by 1

Sirtuin 1 inhibits NLRP3 inflammasome activation through protein-protein interaction

Ho, L., Tsang, Y.-L., Hung, H.-C., Chen, Y.-H., Yang, C.-C., Cheng, Y.-N., Tu, Y.-T., Shao, A., Tsai, P.-J., Lee, Y. S., et al. (2026) · Life Sciences · doi:10.1016/j.lfs.2026.124260 · Cited by 1

A Multifaceted Interplay Among Hemophagocytosis, Interleukin‐18, and Type I Interferon Distinguishes Still Disease From Other Autoinflammatory Diseases

Mueller, Y. M., Girard, C., van de Werken, H. J. G., Erkeland, S. J., Grashof, D. G. B., Vaillant, L., den Dekker, R. J. H., van Zuijen, I., Veenbergen, S., Coffin, F., et al. (2026) · Arthritis & Rheumatology · doi:10.1002/art.70102 · Cited by 1

Delaying cardiac aging: potential mechanisms centered on PANoptosis and targeted intervention strategies

Shu, Y., Li, S., Yang, S., Zhang, S., Li, B., & Dong, L. D. (2026) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2026.1759908 · Cited by 1

Unified phase separation drives DNA-induced inflammasome activation of the AIM2-like receptors

Huang, X., Zhang, Y., Zhao, Z., & Li, X. (2026) · Cell Reports · doi:10.1016/j.celrep.2026.117065 · Cited by 1

Implications of inflammasomes in dental pulp inflammation: immunopathology and therapeutic targeting

Yousefi, M. J., Saleki, K., Afshar, Y., & Rezaei, N. (2026) · Immunopharmacology and Immunotoxicology · doi:10.1080/08923973.2026.2625040 · Cited by 1

Constructing Curcumin-Based Biological Metal–Organic Frameworks (MOFs) for the Treatment of Alzheimer’s Disease Through the Pyroptosis Pathway

Sun, F., Liu, K., Xi, E., Zhao, Y. W., & Gao, N. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27062871 · Cited by 1

DNA-triggered AIM2 condensation orchestrates immune activation and regulation

Li, Q., Geng, X., Yan, H., Li, Z., Shi, M., Zhu, Z., Niu, T., Zhao, C., Shu, K., Gao, Y., et al. (2026) · Protein & Cell · doi:10.1093/procel/pwag024 · Cited by 1

T cell–intrinsic AIM2 exacerbates lung inflammation in OVA-LPS- and HDM-induced asthma models

Chou, W.-C., Hsu, M., Wrobel, J. A., Holley-Guthrie, E., Jania, C. M., Liang, K., Yang, S., Seller, R. S., Hu, X., Schworer, S. A., et al. (2026) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2520215123 · Cited by 1

Tacrine can suppress immune response to tularemia in BALB/c mouse model

Pohanka, M., & Pavliš, O. (2013) · Journal of Applied Biomedicine · doi:10.2478/v10136-012-0021-z · Cited by 2

Nucleic Acid Innate Immune Receptors

Saitoh, S.-I., & Miyake, K. (2019) · Royal Society of Chemistry eBooks · doi:10.1039/9781788015714-00292 · Cited by 1

The Interplay betweenSalmonella entericaSerovar Typhimurium and the Intestinal Mucosa during Oral Infection

Hausmann, A., & Hardt, W. (2020) · John Wiley & Sons, Inc. eBooks · doi:10.1128/9781683670261.ch3 · Cited by 1

Inflammasome effector functions: a Tale of Fire and Ice

Jha, S., & Ting, J. P. ‐. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-91802-2.00031-1 · Cited by 1

Inflammasomes and the Innate Immune Response Against Yersinia Pestis: A Dissertation

Vladimer, G. I. (2013) · The Journal of the American Medical Association (JAMA) Network (American Medical Association) · doi:10.13028/m29w31 · Cited by 1

Innate Immune Signaling and Negative Regulators in Cancer

Wang, H. Y., & Wang, R. (2011) · Springer eBooks · doi:10.1007/978-1-4419-9914-6_6 · Cited by 1

Regulation of Intracellular dsDNA-Induced Innate Immune Responses by Autophagy-Related Proteins

Saitoh, T. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-404732-7.00004-6 · Cited by 1

Autophagy Accompanies Inflammasome Activation to Moderate Inflammation by Eliminating Active Inflammasomes

Nabar, N. R., Shi, C.-S., & Kehrl, J. H. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-812146-7.00016-0 · Cited by 1

Inflammasomes

Inoue, M., Kanayama, M., & Shinohara, M. L. (2016) · Compendium of Inflammatory Diseases · doi:10.1007/978-3-7643-8550-7_77 · Cited by 1

Mechanisms for activation and inhibition of inflammasomes

Janczy, J. R. (2014) · doi:10.17077/etd.gqld9sco · Cited by 1

Pathogenesis of Orientia tsutsugamushi Infection in Humans

Tantibhedhyabgkul, W., & Mège, J. (2015) · doi:10.1002/9781118644843.ch46 · Cited by 1

A Continuous IC Glaciochemical Record of the last Glacial Period from the NGRIP Ice Core

Siggaard‐Andersen, M., Hansson, M., Fischer, H., Bigler, M., Roethlisberger, R., Goto‐Azuma, K., Steffensen, J. P., Ruth, U., Andersen, K. K., Clausen, H. B., et al. (2005) · AGUFM · Cited by 1

Pyroptosis

Lawlor, K. E., Conos, S. A., & Vince, J. E. (2018) · Wiley eBooks · doi:10.1002/9781119432463.ch15 · Cited by 1

Faculty Opinions recommendation of The NLRP6 Inflammasome Recognizes Lipoteichoic Acid and Regulates Gram-Positive Pathogen Infection.

Triantafilou, K. (2019) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.734357156.793560837 · Cited by 1

Role of AIM2 Inflammasome in Pulmonary Host Defense Against Staphylococcus aureus-induced Pneumonia

Dhakal, B. (2021) · Louisiana State University · doi:10.31390/gradschool_theses.5456 · Cited by 1

Type-I IFNs induce GBPs and lysosomal defense in hepatocytes to control malariaPreprint

Marques-da-Silva, C., Schmidt-Silva, C., Bowers, C., Charles-Chess, N. A. E., Shiau, J. C., Park, E., Yuan, Z., Kim, B.-H., Kyle, D. E., Harty, J. T., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.10.22.619707 · Cited by 1

Environmental Amino Acid Sensing Regulates the Rate of ASC Translation and NLRP3 Inflammasome AssemblyPreprint

Haggadone, M. D., Goldspiel, B. P., O’Farrell, A., Kiledjian, N. T., Knight, M., Smith, T., Anderson, E., Marrero, V. R. V., Boyer, M. A., Xu, P. J., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.01.16.699988 · Cited by 1

Sensing of Endogenous Nucleic Acids by the Innate Immune System during Viral Infection: A Dissertation

Schattgen, S. (2015) · doi:10.13028/m2h88k

Francisella tularensis: Regulation of Gene Expression, Intracellular Trafficking, and Subversion of Host Defenses

Mohapatra, N. P., Dai, S., & Gunn, J. S. (2016) · ASM Press eBooks · doi:10.1128/9781555818524.ch21

Avaliação dos mecanismos moleculares envolvidos na expressão de iNOS mediada pelo eixo NAIP5/NLRC4-Caspase-1.

Carina Cristina Oliveira de, L. I. M. A. (2014) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.42.2014.tde-11072014-093448

Analysis of Toll-like receptors and retinoic-acid-inducible gene-I (RIG-I)-like helicases in human neutrophils and HL60 cells

Hsieh, C.-Y. (2012) · doi:10.5282/edoc.15208

Activation of inflammasome and protein secretion by endogenous danger and microbe-derived signals in human macrophages

Välimäki, E. (2015) · Työväentutkimus Vuosikirja

Dissecting the Role of Cytosolic Nucleic Acid Sensors in the Type I Interferon Response to Herpes Simplex Virus-1 and other Ligands: A Dissertation

Thompson, M. (2014) · The Journal of the American Medical Association (JAMA) Network (American Medical Association) · doi:10.13028/m20w37

Type I Interferon is Not Just for Viruses: Cytosolic Sensing of Bacterial Nucleic Acids

Monroe, K. M. (2011) · eScholarship (California Digital Library)

Sensing DNA Viruses and Bacteria by Intracellular DNA Sensors

Lee, N.-R., Shin, H.-B., Kim, H. I., Choi, M.-S., & Inn, K. (2013) · Journal of Bacteriology and Virology · doi:10.4167/jbv.2013.43.2.77

Mvin mediates Francisella Tularensis virulence through evasion of AIM2 inflammasome activation

Ulland, T. K. (2010) · doi:10.17077/etd.c04zmq85

Pattern recognition receptors: sentinels in innate immunity and targets of new vaccine

Olive, C. (2012)

Role of type I interferons in Streptococcus pneumoniae pneumonia

Olbertz, J.-H., der Mathematisch-Naturwissenschaftlichen, D., Fakultät, I., & Herrmann, A. (2012)

The present and future of serology

Borobio, M. V. (2003) · Enfermedades Infecciosas y Microbiología Clínica

Role of the inflammasome pathway in atherosclerosis

Rajamäki, K. (2015) · Työväentutkimus Vuosikirja

Viral Infections and the DNA Sensing Pathway: Lessons from Herpesviruses and Beyond

Paludan, S. R., & Bowie, A. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-404732-7.00008-3

NAIP and CARD-only proteins in inflammasome signaling

Matusiak, M. (2015) · Ghent University Academic Bibliography (Ghent University)

Innate Immune Signaling by, and Genetic Adjuvants for

Kobiyama, K., Jounai, N., Aoshi, T., Tozuka, M., Takeshita, F., Coban, C., & Ishii, K. J. (2013)

The Duality of AIM2 Inflammasome: A Focus on its Role in Autoimmunity and Skin Diseases

Canavese, M. (2016) · American Journal of Pharmacology and Toxicology · doi:10.3844/ajptsp.2016.8.19

Bacterial Infections and the DNA Sensing Pathway

Naujoks, J., & Opitz, B. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-404732-7.00007-1

Pathogen-Host Cell Interactions at the Intestinal Level: Lessons from Cultured Human Fully-Differentiated Colon Cancer Caco-2 and T84 Epithelial Cell Lines

Schiffrin, E. J., Marteau, P. R., & Brassart, D. (2014) · CRC Press eBooks · doi:10.1201/b16442-6

Nucleic Acid Detection in Anti-Viral Responses and Autoimmunity

Brunette, R. L. (2012) · ResearchWorks at the University of Washington (University of Washington)

Vaccinia protein C16 blocks innate immune sensing of DNA by binding the Ku complex

Peters, N. (2011) · Spiral (Imperial College London) · doi:10.25560/8960

Signaling and Effector Molecules in Immunity

Milone, M. C. (2017) · Molecular and integrative toxicology · doi:10.1007/978-3-319-47377-2_3

Papel de inflamassomas e vias lisossomais na morte celular e resposta imune induzidas pela flagelina.

Lage, S. L. (2016) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.42.2016.tde-25022016-095353

O papel da sílica mesoporosa nanoestruturada SBA-15 na ativação do inflamassoma NLRP3.

Gabrili, J. J. M. (2016) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/d.42.2016.tde-16082016-112249

Inflammasomefor Rapid Activation of the NLRP3 Cutting Edge: TLR Signaling Licenses

Alnemri, S., Fitzgerald, K. A., Fernandes-Alnemri, E. T., & Kang, S. (2013)

Comparative Gene Expression Analysis within Mouse Macrophage for Identifying Critical Pathways in Macrophage and Brucella suis Interaction

Hu, J., Wang, T., Zhao, H., Song, Y., Han, Q., Zhang, J., Shou, T., Zhang, F., Xia, X., & Chen, Q. (2017) · Jundishapur Journal of Microbiology · doi:10.5812/jjm.59275

A matter of life or death

Schwartz, J. T. (2013) · doi:10.17077/etd.xgxbxs7a

Treatment of mice with IL2-complex enhances inflammasome-driven IFN-γ production and prevents lethal toxoplasmosisPreprint

Kupz, A., Pai, S., Giacomin, P., Whan, J. A., Walker, R. A., Hammoudi, P., Smith, N. C., & Miller, C. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/593574

Transcriptional Regulation of NLRC4 Inflammasome by IRF8

Lee, E. (2019) · doi:10.21007/etd.cghs.2019.0458

Assessment of inflammasome and type I IFN responses to DNA viruses and DNA PAMPS

Massaccesi, G., & Chattergoon, M. A. (2019) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/bs.mie.2019.05.008

Roles of Cytosolic Nucleic Acid Sensors in Cancer and Infection

Zu, Q. (2018) · doi:10.21007/etd.cghs.2018.0462

Francisella

Johansson, A.-L., Noppa, L., Salomonsson, E. N., & Försberg, Å. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-397169-2.00108-6 · Cited by 1

Evasion of type I IFN signaling by the small hydrophobic protein of HMPV and the implications for viral replication and pathogenesis

Hastings, A. K. (2015)

Characterization of NLRP1B Inflammasome Activation

Neiman-Zenevich, J. (2017) · TSpace (University of Toronto)

Роль ДНК-сенсоров в рекогниции патоген-ассоциированных молекулярных структур инфекционных патогенных агентов и развитии воспаления. Часть 2. Семейство HIN-200 протеинов

Абатуров, А. Е., Волосовец, А. П., & Yulish, Y. I. (2014) · CHILD`S HEALTH · doi:10.22141/2224-0551.1.52.2014.75628

Faculty Opinions recommendation of The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells.

Cherry, S. R., & Panda, D. (2012) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.13327992.791102831

Cellular Exit Strategies of Intracellular Bacteria

Hybiske, K., & Stephens, R. S. (2016) · ASM Press eBooks · doi:10.1128/9781555819286.ch25

Inflammasomes

Inoue, M., Kanayama, M., & Shinohara, M. L. (2013) · Encyclopedia of Inflammatory Diseases · doi:10.1007/978-3-0348-0620-6_77-1

Faculty Opinions recommendation of Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria.

Paumet, F., & Wesolowski, J. (2010) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.6275956.6987054

Faculty Opinions recommendation of An NLRP7-containing inflammasome mediates recognition of microbial lipopeptides in human macrophages.

Triantafilou, K. (2013) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.717968582.793468367

Faculty Opinions recommendation of Human caspase-4 detects tetra-acylated LPS and cytosolic Francisella and functions differently from murine caspase-11.

Weiss, J. P. (2018) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.732498116.793545009

Faculty Opinions recommendation of Elevated AIM2-mediated pyroptosis triggered by hypercytotoxic Francisella mutant strains is attributed to increased intracellular bacteriolysis.

Mann, B. (2011) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.13360076.14730213

Faculty Opinions recommendation of The E3 ubiquitin ligase TRIM21 negatively regulates the innate immune response to intracellular double-stranded DNA.

Leib, D. (2012) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.717967999.793467778

Discovery of Bakuchiol as Aim2 Inflammasome Activator and Cause HepatotoxicityPreprint

Liu, T., Guang, X., Li, Y., Wei, S., Ren, L., Zhie, F., Liang, L., Wang, Y., Gao, Y., Xiaoyan, Z., et al. (2022) · SSRN Electronic Journal · doi:10.2139/ssrn.4145409

Caracterização de células e moléculas do sistema imune inato envolvidas na progressão e tratamento de lesão periapical e no desenvolvimento da doença periodontal

Pucinelli, C. M. (2019) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.58.2019.tde-30092022-102310

Collagen I is expressed by hepatocytes through activation of AIM2/ASC/caspase-1 signaling pathwayPreprint

Sheng, Q., Zhai, P., Chen, L., Zhou, L., Ou, X., Situ, B., Huang, J. S., & Pan, X. (2023) · Research Square · doi:10.21203/rs.3.rs-2360883/v1

Francisella tularensis

Qin, A., Moreau, G. B., Barry, E. M., & Mann, B. J. (2024) · Elsevier eBooks · doi:10.1016/b978-0-12-818619-0.00032-0

Avaliação da participação de diferentes inflamassomas no reconhecimento e no controle da infecção experimental por Legionella longbeachae

Guerra, R. O. (2024) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/d.17.2024.tde-10062024-092259

Summary

(2016)

Sensing Cytoplasmic Danger Signals by the Inflammasome

Alnemri, E. S. (2010) · Journal of Clinical Immunology · doi:10.1007/s10875-010-9419-0 · Cited by 64

Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis

Jones, J. W. M., Kayagaki, N., Brož, P., Henry, T., Newton, K., O’Rourke, K. M., Chan, S. B., Dong, J. J., Qu, Y., Roose-Girma, M., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1003738107 · Cited by 487

Characterization of the Role of Francisella‐Sensing Inflammasomes in the Development of Innate and Vaccine‐ Induced Immunity

Alqahtani, M. (2020) · Touro Scholar (Touro College)

The role of AIM2 and NLRP12 in the innate immune response to Francisella tularensis

Ulland, T. K. (2014) · doi:10.17077/etd.680pwptd