Reply to: "Can DCs be distinguished from macrophages by molecular signatures?"

<i>Batf3</i> Deficiency Reveals a Critical Role for CD8α ⁺ Dendritic Cells in Cytotoxic T Cell Immunity

Hildner, K., Edelson, B. T., Purtha, W. E., Diamond, M., Matsushita, H., Kohyama, M., Calderon, B., Schraml, B. U., Unanue, E. R., Diamond, M. S., et al. (2008) · Science · doi:10.1126/science.1164206 · Cited by 2,081 · see citing works

Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages

the Immunological Genome Consortium, Gautier, E. L., Shay, T., Miller, J., Greter, M., Jakubzick, C., Ivanov, S., Helft, J., Chow, A., Elpek, K. G., et al. (2012) · Nature Immunology · doi:10.1038/ni.2419 · Cited by 1,972 · see citing works

Cd8+ but Not Cd8− Dendritic Cells Cross-Prime Cytotoxic T Cells in Vivo

den Haan, J. M. M., Lehar, S. M., & Bevan, M. J. (2000) · The Journal of Experimental Medicine · doi:10.1084/jem.192.12.1685 · Cited by 1,319 · see citing works

Deciphering the transcriptional network of the dendritic cell lineage

Miller, J. C., Brown, B. D., Shay, T., Gautier, E. L., Jojic, V., Cohain, A. T., Pandey, G. S., Leboeuf, M., Elpek, K. G., Helft, J., et al. (2012) · Nature Immunology · doi:10.1038/ni.2370 · Cited by 779 · see citing works

The origin and development of nonlymphoid tissue CD103+ DCs

Ginhoux, F., Liu, K., Helft, J., Bogunovic, M., Greter, M., Hashimoto, D., Price, J. G., Yin, N., Bromberg, J. S., Lira, S. A., et al. (2009) · The Journal of Experimental Medicine · doi:10.1084/jem.20091756 · Cited by 744 · see citing works

Peripheral CD103+ dendritic cells form a unified subset developmentally related to CD8α+ conventional dendritic cells

Edelson, B. T., Wumesh, K. C., Juang, R., Kohyama, M., Benoît, L. A., Klekotka, P. A., Moon, C., Albring, J. C., Ise, W., Michael, D. G., et al. (2010) · The Journal of Experimental Medicine · doi:10.1084/jem.20091627 · Cited by 710 · see citing works

Cross-presentation of viral and self antigens by skin-derived CD103+ dendritic cells

Bedoui, S., Whitney, P. G., Waithman, J. C., Eidsmo, L., Wakim, L. M., Caminschi, I., Allan, R. S., Wojtasiak, M., Shortman, K., Carbone, F., et al. (2009) · Nature Immunology · doi:10.1038/ni.1724 · Cited by 707 · see citing works

The CD8+ Dendritic Cell Subset Selectively Endocytoses Dying Cells in Culture and In Vivo

Iyoda, T., Shimoyama, S., Liu, K., Omatsu, Y., Akiyama, Y., Maeda, Y., Takahara, K., Steinman, R. M., & Inaba, K. (2002) · The Journal of Experimental Medicine · doi:10.1084/jem.20020161 · Cited by 647 · see citing works

Zbtb46 expression distinguishes classical dendritic cells and their committed progenitors from other immune lineages

Satpathy, A. T., Wumesh, K. C., Albring, J. C., Edelson, B. T., Kretzer, N. M., Bhattacharya, D., Murphy, T. L., & MURPHY, K. M. M. (2012) · The Journal of Experimental Medicine · doi:10.1084/jem.20120030 · Cited by 628 · see citing works

Expression of the zinc finger transcription factor zDC (Zbtb46, Btbd4) defines the classical dendritic cell lineage

Meredith, M. M., Liu, K., Darrasse-Jeze, G., Kamphorst, A. O., Schreiber, H. A., Guermonprez, P., Idoyaga, J., Cheong, C., Yao, K.-H., Niec, R. E., et al. (2012) · Journal of Experimental Medicine · doi:10.1084/jem.20112675 · Cited by 524 · see citing works

CD207+ CD103+ dermal dendritic cells cross-present keratinocyte-derived antigens irrespective of the presence of Langerhans cells

Henri, S., Poulin, L. F., Tamoutounour, S., Ardouin, L., Guilliams, M., de Bovis, B., Devilard, É., Viret, C., Azukizawa, H., Kissenpfennig, A., et al. (2009) · The Journal of Experimental Medicine · doi:10.1084/jem.20091964 · Cited by 402 · see citing works

Dendritic Cell and Macrophage Heterogeneity In Vivo

Hashimoto, D., Miller, J. C., & Mérad, M. (2011) · Immunity · doi:10.1016/j.immuni.2011.09.007 · Cited by 366 · see citing works

CD103− and CD103+ Bronchial Lymph Node Dendritic Cells Are Specialized in Presenting and Cross-Presenting Innocuous Antigen to CD4+ and CD8+ T Cells

del Rio, M., Rodríguez-Barbosa, J.-I., Kremmer, E., & Förster, R. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.178.11.6861 · Cited by 319 · see citing works

CD103+ pulmonary dendritic cells preferentially acquire and present apoptotic cell–associated antigen

Desch, A. N., Randolph, G. J., MURPHY, K. M. M., Gautier, E. L., Kedl, R. M., Lahoud, M. H., Caminschi, I., Shortman, K., Henson, P. M., & Jakubzick, C. (2011) · The Journal of Experimental Medicine · doi:10.1084/jem.20110538 · Cited by 305 · see citing works

Securing the immune tightrope: mononuclear phagocytes in the intestinal lamina propria

Varol, C., Zigmond, E., & Jung, S. (2010) · Nature reviews. Immunology · doi:10.1038/nri2778 · Cited by 208 · see citing works

Subcapsular Sinus Macrophage Fragmentation and CD169+ Bleb Acquisition by Closely Associated IL-17-Committed Innate-Like Lymphocytes

Gray, E. E., Friend, S. L., Suzuki, K., Phan, T. G., & Cyster, J. G. (2012) · PLoS ONE · doi:10.1371/journal.pone.0038258 · Cited by 94 · see citing works

Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage

Aran, D., Looney, A. P., Liu, L., Wu, E., Fong, V., Hsu, A., Chak, S., Naikawadi, R. P., Wolters, P. J., Abate, A. R., et al. (2019) · Nature Immunology · doi:10.1038/s41590-018-0276-y · Cited by 4,984 · see citing works

Where are we? The anatomy of the murine cortical meninges revisited for intravital imaging, immunology, and clearance of waste from the brain

Coles, J. A., Myburgh, E., Brewer, J. M., & McMenamin, P. G. (2017) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2017.05.002 · Cited by 123 · see citing works

Mafb lineage tracing to distinguish macrophages from other immune lineages reveals dual identity of Langerhans cells

Wu, X., Briseño, C. G., Durai, V., Albring, J. C., Haldar, M., Bagadia, P., Kim, K.-W., Randolph, G. J., Murphy, T. L., & MURPHY, K. M. M. (2016) · The Journal of Experimental Medicine · doi:10.1084/jem.20160600 · Cited by 116 · see citing works

Innate immune regulation by STAT ‐mediated transcriptional mechanisms

Li, H. S., & Watowich, S. S. (2014) · Immunological Reviews · doi:10.1111/imr.12198 · Cited by 71 · see citing works

Epithelial Basal Cells Are Distinct from Dendritic Cells and Macrophages in the Mouse Epididymis1

Shum, W. W., Smith, T., Cortez‐Retamozo, V., Grigoryeva, L. S., Roy, J. W., Hill, E., Pittet, M. J., Breton, S., & Silva, N. D. (2014) · Biology of Reproduction · doi:10.1095/biolreprod.113.116681 · Cited by 70 · see citing works

Dendritic Cell-Based Immunotherapy in Multiple Myeloma: Challenges, Opportunities, and Future Directions

Verheye, E., Melgar, J. B., Deschoemaeker, S., Raes, G., Maes, A., Bruyne, E. D., Menu, E., Vanderkerken, K., Laoui, D., & Veirman, K. D. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23020904 · Cited by 54 · see citing works

CD11c‐positive cells from brain, spleen, lung, and liver exhibit site‐specific immune phenotypes and plastically adapt to new environments

Immig, K., Gericke, M. T., Menzel, F., Merz, F., Krueger, M., Schiefenhövel, F., Lösche, A., Jäger, K., Hanisch, U., Biber, K. P. H., et al. (2014) · Glia · doi:10.1002/glia.22771 · Cited by 44 · see citing works

Exploiting tumor-associated dendritic cell heterogeneity for novel cancer therapies

Keirsse, J., Damme, H. V., Ginderachter, J. A. V., & Laoui, D. (2017) · Journal of Leukocyte Biology · doi:10.1189/jlb.4mr1116-466r · Cited by 31 · see citing works

Characterization of regulatory dendritic cells differentiated from the bone marrow of UV ‐irradiated mice

Ng, R. L. X., Scott, N. M., Bisley, J. L., Lambert, M. J. M., Gorman, S., Norval, M., & Hart, P. H. (2013) · Immunology · doi:10.1111/imm.12145 · Cited by 21 · see citing works

Hyaluronan Binding Identifies a Functionally Distinct Alveolar Macrophage–like Population in Bone Marrow–Derived Dendritic Cell Cultures

Poon, G. F. T., Dong, Y., Marshall, K. C., Arif, A., Deeg, C., Dosanjh, M., & Johnson, P. (2015) · The Journal of Immunology · doi:10.4049/jimmunol.1402506 · Cited by 18 · see citing works

A Guide to Bioinformatics for Immunologists

Whelan, F., Yap, N. V. L., Surette, M. G., Golding, G. B., & Bowdish, D. M. E. (2013) · Frontiers in Immunology · doi:10.3389/fimmu.2013.00416 · Cited by 17 · see citing works

Genomic and molecular control of cell type and cell type conversions

Fu, X., He, F., Li, Y., Shahveranov, A., & Hutchins, A. P. (2017) · Cell Regeneration · doi:10.1016/j.cr.2017.09.001 · Cited by 13 · see citing works

Toward defining a ‘lineage’ – The case for dendritic cells

Perié, L., & Naik, S. H. (2015) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2015.02.004 · Cited by 11 · see citing works

Can DCs be distinguished from macrophages by molecular signatures?

Hume, D. A., Mabbott, N., Raza, S., & Freeman, T. C. (2013) · Nature Immunology · doi:10.1038/ni.2516 · Cited by 69 · see citing works

A Basis for Distinguishing Cultured Dendritic Cells and Macrophages in Cytospins and Fixed Sections

Vakkila, J., Lotze, M. T., Riga, C., & Jaffe, R. (2005) · Pediatric and Developmental Pathology · doi:10.1007/s10024-004-5045-2 · Cited by 27 · see citing works

capable of differentiating into macrophages

Odegaard, J. I., Vats, D., Zhang, L., Ricardo-González, R. R., Smith, K. L., Sykes, D. B., Kamps, M. P., & Chawla, A. (2006)

Unique Proteomic Signatures Distinguish Macrophages and Dendritic Cells

Becker, L., Liu, N.-C., Averill, M. M., Yuan, W., Pamir, N., Peng, Y., Irwin, A. D., Fu, X., Bornfeldt, K., & Heinecke, J. W. (2012) · PLoS ONE · doi:10.1371/journal.pone.0033297 · Cited by 102 · see citing works

New connections: Species-specific immune responses

Foley, J. F. (2016) · Science Signaling · doi:10.1126/scisignal.aaf8944 · Cited by 1 · see citing works