The DOI matches its Crossref record; 150 of the 150 references it cites were found in a registry or an index.
Gene regulation in the immune system by long noncoding RNAs
Open accessAbstract
Long noncoding RNAs (lncRNAs) are emerging as critical regulators of gene expression in the immune system. Studies have shown that lncRNAs are expressed in a highly lineage-specific manner and control the differentiation and function of innate and adaptive cell types. In this Review, we focus on mechanisms used by lncRNAs to regulate genes encoding products involved in the immune response, including direct interactions with chromatin, RNA and proteins. In addition, we address new areas of lncRNA biology, such as the functions of enhancer RNAs, circular RNAs and chemical modifications to RNA in cellular processes. We emphasize critical gaps in knowledge and future prospects for the roles of lncRNAs in the immune system and autoimmune disease.
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1 retracted
DDX5 and its associated lncRNA Rmrp modulate TH17 cell effector functions
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Self-citationLandscape of transcription in human cells
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Self-citationCircular RNAs are abundant, conserved, and associated with ALU repeats
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Cited by
Gene regulation by long non-coding RNAs and its biological functions
Statello, L., Guo, C.-J., Chen, L.-L., & Huarte, M. (2021) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-020-00315-9 · Cited by 4,991
Cytoplasmic functions of long noncoding RNAs
Noh, J. H., Kim, K. M., McClusky, W. G., Abdelmohsen, K., & Gorospe, M. (2018) · WIREs RNA · doi:10.1002/wrna.1471 · Cited by 432
Epigenetic regulation of the innate immune response to infection
Zhang, Q., & Cao, X. (2019) · Nature Reviews Immunology · doi:10.1038/s41577-019-0151-6 · Cited by 366
RNA-binding proteins control gene expression and cell fate in the immune system
Turner, M., & Díaz-Muñoz, M. D. (2018) · Nature Immunology · doi:10.1038/s41590-017-0028-4 · Cited by 209
Regulation of long non-coding RNAs and genome dynamics by the RNA surveillance machinery
Nair, L., Chung, H., & Basu, U. (2020) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-019-0209-0 · Cited by 203
Metadata
- Authors
- Chen, Y. G., Satpathy, A. T., & Chang, H. Y.
- Venue
- Nature Immunology
- Published
- 2017-08-22
- Volume
- 18
- Issue
- 9
- Pages
- 962-972
- ISSN
- 1529-2908 (ISSN-L)
- 1529-2916
- OpenAlex
- W2748551035
- Cited by
- 697
- References
- 150
- FWCI
- 21.04
- Type
- journal article
- Language
- en
- Open access
- green
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