Intracellular NAD levels regulate tumor necrosis factor protein synthesis in a sirtuin-dependent manner

Van Gool, Frédéric, Gallí, Mara, Gueydan, Cyril, Kruys, Véronique, Prevot, Pierre-Paul, Bedalov, Antonio, Mostoslavsky, Raul, Alt, Frederick W +2 more·2009·Nature Medicine

DOI 10.1038/nm.1906

Cited by (289)

Items 101–200 of 289

Sirtuin 2 Deficiency Increases Bacterial Phagocytosis by Macrophages and Protects from Chronic Staphylococcal Infection
Eleonora Ciarlo, Tytti Heinonen, Charlotte Théroude, Jacobus Herderschee, Matteo Mombelli, Jérôme Lugrin, Marc Pfefferlé, Beatrice E. Tyrrell, Sarah Lensch, Hans Acha‐Orbea et al. · 2017 · Frontiers in Immunology
Suppression of leukocyte infiltration and cartilage degradation by selective inhibition of pre-B cell colony-enhancing factor/visfatin/nicotinamide phosphoribosyltransferase: Apo866-mediated therapy in human fibroblasts and murine collagen-induced arthrit
Laura Evans, Anwen S. Williams, Anthony J. Hayes, Simon A. Jones, Mari A. Nowell · 2011 · Arthritis & Rheumatism
Characterization of Nuclear Sirtuins: Molecular Mechanisms and Physiological Relevance
Debra Toiber, Carlos Sebastián, Raúl Mostoslavsky · 2011 · Handbook of experimental pharmacology
Sirtuins in dermatology: applications for future research and therapeutics
Melissa Serravallo, Jared R. Jagdeo, Sharon A. Glick, Daniel Mark Siegel, Neil Brody · 2013 · Archives of Dermatological Research
Macrophage metabolism, phenotype, function, and therapy in hepatocellular carcinoma (HCC)
Jingquan Huang, Qiulin Wu, David A. Geller, Yihe Yan · 2023 · Journal of Translational Medicine
Stretch and inflammation-induced Pre-B cell colony-enhancing factor (PBEF/Visfatin) and Interleukin-8 in amniotic epithelial cells
Claire E. Kendal‐Wright, D. Hubbard, J. Gowin-Brown, Gillian D. Bryant-Greenwood · 2010 · Placenta
ddhCTP produced by the radical‐SAM activity of RSAD2 (viperin) inhibits the NAD+‐dependent activity of enzymes to modulate metabolism
Kourosh Honarmand Ebrahimi, Jane Vowles, Cathy Browne, James McCullagh, William James · 2020 · FEBS Letters
Transcriptome analysis of monocyte-HIV interactions
Rafaël Van den Bergh, Éric Florence, Erika Vlieghe, Tom Boonefaes, Johan Grooten, Erica Houthuys, Huyen Thi Thanh Tran, Youssef Gali, Patrick DE BAETSELIER, Guido Vanham et al. · 2010 · Retrovirology
Trichostatin A inhibits deacetylation of histone H3 and p53 by SIRT6
Marci Wood, Stacia Rymarchyk, Song Guo Zheng, Yana Cen · 2017 · Archives of Biochemistry and Biophysics
NAD+ metabolism-based immunoregulation and therapeutic potential
Jiankai Fang, Wangwang Chen, Pengbo Hou, Zhanhong Liu, Muqiu Zuo, Shisong Liu, Chao Feng, Yuyi Han, Peishan Li, Yufang Shi et al. · 2023 · Cell & Bioscience
Sirtuins and inflammation: Friends or foes?
Mara Gallí, Frédéric Van Gool, Oberdan Léo · 2010 · Biochemical Pharmacology
Targeting Sirtuins: Substrate Specificity and Inhibitor Design
Nima Rajabi, Iacopo Galleano, Andreas S. Madsen, Christian Adam Olsen · 2018 · Progress in molecular biology and translational science
Rejuvenating Sirtuins: The Rise of a New Family of Cancer Drug Targets
Santina Bruzzone, Marco Daniele Parenti, Alessia Grozio, Alberto Ballestrero, Inga Bauer, Alberto Del Río, Alessio Nencioni · 2012 · Current Pharmaceutical Design
Nicotinamide phosphoribosyltransferase inhibition reduces intraplaque CXCL1 production and associated neutrophil infiltration in atherosclerotic mice
Rafaela da Silva, Rodrigo A. Fraga-Silva, Sabine Steffens, Mathias Fabre, Inga Bauer, Irene Caffa, Mirko Magnone, Giovanna Sociali, Alessandra Quercioli, Graziano Pelli et al. · 2013 · Thrombosis and Haemostasis
NAMPT/PBEF1 enzymatic activity is indispensable for myeloma cell growth and osteoclast activity
Sathisha Upparahalli Venkateshaiah, Sharmin Khan, Wen Ling, Rakesh Bam, Xin Li, Frits van Rhee, Saad Z. Usmani, Bart Barlogie, Joshua Epstein, Shmuel Yaccoby · 2013 · Experimental Hematology
NAMPT-Mediated Salvage Synthesis of NAD+ Controls Morphofunctional Changes of Macrophages
Gerda Venter, Frank T. J. J. Oerlemans, Marieke P. Willemse, Mietske Wijers, Jack A. M. Fransen, Bé Wieringa · 2014 · PLoS ONE
Epigenetic Regulation of Metabolism and Inflammation by Calorie Restriction
Diego Hernández‐Saavedra, Laura Moody, Guanying Bianca Xu, Hong Chen, Yuan‐Xiang Pan · 2018 · Advances in Nutrition
NAMPT/SIRT1 Attenuate Ang II-Induced Vascular Remodeling and Vulnerability to Hypertension by Inhibiting the ROS/MAPK Pathway
Lei Zhou, Sheng Zhang, Enkhbat Bolor-Erdene, Lingwei Wang, Tian Ding, Yunqing Mei · 2020 · Oxidative Medicine and Cellular Longevity
SIRT6 enhances oxidative phosphorylation in breast cancer and promotes mammary tumorigenesis in mice
Pamela Becherini, Irene Caffa, Francesco Piacente, Patrizia Damonte, Valerio Gaetano Vellone, Mario Passalacqua, Andrea Benzi, Tommaso Bonfiglio, Daniele Reverberi, A. Khalifa et al. · 2021 · Cancer & Metabolism
Down-regulation of NAMPT expression by miR-182 is involved in Tat-induced HIV-1 long terminal repeat (LTR) transactivation
Xin-Yu Chen, Hongsheng Zhang, Tong‐Chao Wu, Wei-Wei Sang, Zheng Ruan · 2012 · The International Journal of Biochemistry & Cell Biology
Nicotinamide Phosphoribosyltransferase Inhibitor Is a Novel Therapeutic Candidate in Murine Models of Inflammatory Lung Injury
Liliana Moreno‐Vinasco, Hector Quijada, Saad Sammani, Jessica H. Siegler, Eleftheria Letsiou, Ryan J. Deaton, Laleh Saadat, Rafe Zaidi, Joe Messana, Peter H. Gann et al. · 2014 · American Journal of Respiratory Cell and Molecular Biology
Sirtuin inhibition attenuates the production of inflammatory cytokines in lipopolysaccharide-stimulated macrophages
Cláudia A. Fernandes, Laurence Fiévez, Audrey M. Neyrinck, Nathalie M. Delzenne, Fabrice Bureau, Rita Vanbever A · 2012 · Biochemical and Biophysical Research Communications
Nicotinamide Exacerbates Hypoxemia in Ventilator-Induced Lung Injury Independent of Neutrophil Infiltration
Heather D. Jones, Jeena Yoo, Timothy R. Crother, Pierre A. Kyme, Anat Ben-Shlomo, Ramtin Khalafi, Ching Wen Tseng, William C. Parks, Moshe Arditi, George Y. Liu et al. · 2015 · PLoS ONE
Visfatin and Cardio–Cerebro–Vascular Disease
Pei Wang, Paul M. Vanhoutte, Chao‐Yu Miao · 2011 · Journal of Cardiovascular Pharmacology
Sirtuin-1 in immunotherapy: A Janus-headed target
Sakshum Chadha, Liqing Wang, Wayne W. Hancock, Ulf Henning Beier · 2019 · Journal of Leukocyte Biology
Tanshinone II A Inhibits Tat‐Induced HIV‐1 Transactivation Through Redox‐Regulated AMPK/Nampt Pathway
Hongsheng Zhang, Xinyu Chen, Tong‐Chao Wu, Feng‐Juan Zhang · 2014 · Journal of Cellular Physiology
Regulation and protection of mitochondrial physiology by sirtuins
Cláudia V. Pereira, Magdalena Lebiedzińska, Mariusz Roman Wieckowski, Paulo Jorge Oliveira · 2011 · Mitochondrion
SIRT6 inhibitors with salicylate-like structure show immunosuppressive and chemosensitizing effects
Patrizia Damonte, Giovanna Sociali, Marco Daniele Parenti, Debora Soncini, Inga Bauer, Silvia Boero, Alessia Grozio, Maria von Holtey, Francesco Piacente, Pamela Becherini et al. · 2017 · Bioorganic & Medicinal Chemistry
Sirt6 inhibition delays the onset of experimental autoimmune encephalomyelitis by reducing dendritic cell migration
Giovanni Battista Ferrara, Andrea Benzi, Laura Sturla, Daniela Marubbi, Davide Frumento, Sonia Spinelli, Elena Abbotto, Federico Ivaldi, Maria von Holtey, Maximilien Murone et al. · 2020 · Journal of Neuroinflammation
Epigenetic regulation of NKG2D ligands is involved in exacerbated atherosclerosis development in Sirt6 heterozygous mice
Zhu‐Qin Zhang, Sichong Ren, Ying Tan, Zuo-Zhi Li, Xiaoqiang Tang, Tingting Wang, De‐Long Hao, Xiang Zhao, Hou‐Zao Chen, De‐Pei Liu · 2016 · Scientific Reports
Aspects of Tryptophan and Nicotinamide Adenine Dinucleotide in Immunity: A New Twist in an Old Tale
Héctor Rodríguez Cetina Biefer, Anju Vasudevan, Abdallah Elkhal · 2017 · International Journal of Tryptophan Research
Role of Sirtuins in Tumor Angiogenesis
Lincy Edatt, Aswini Poyyakkara, Grace R. Raji, Vishnu Ramachandran, Sarojini Sharath Shankar, V.B. Sameer Kumar · 2020 · Frontiers in Oncology
Modulating Sirtuin Biology and Nicotinamide Adenine Diphosphate Metabolism in Cardiovascular Disease—From Bench to Bedside
Yu-Jen Wang, Francesco Paneni, Sokrates Stein, Christian M. Matter · 2021 · Frontiers in Physiology
Sirtuins: The NAD + -Dependent Multifaceted Modulators of Inflammation
Leonardo Santos, Andrés Benítez-Rosendo, Mariana Bresque, Juliana Camacho-Pereira, Aldo J. Calliari, Carlos Escande · 2023 · Antioxidants and Redox Signaling
Intracellular NAD+ levels are associated with LPS-induced TNF-α release in pro-inflammatory macrophages
Abbas Jawad Al-Shabany, A. John Moody, Andrew Foey, Richard A. Billington · 2016 · Bioscience Reports
Inhibition of nicotinamide phosphoribosyltransferase modifies LPS-induced inflammatory responses of human monocytes
Erik Schilling, Janine Wehrhahn, Carina Klein, Nora Raulien, Uta Ceglarek, Sunna Hauschildt · 2011 · Innate Immunity
MiR-125b attenuates human hepatocellular carcinoma malignancy through targeting SIRT6.
Song Shi, Yuxia Yang, Minghui Liu, Boya Liu, Xin Ping Yang, Miao Yu, Hao Qi, Mengmeng Ren, Zhe Wang, Junhua Zou et al. · 2018 · Europe PMC (PubMed Central)
Nicotinamide riboside exerts protective effect against aging-induced NAFLD-like hepatic dysfunction in mice
Xue Han, Xiaogang Bao, Qi Lou, Xian Ming Xie, Meng Zhang, Shasang Zhou, Honggang Guo, Guojun Jiang, Qiaojuan Shi · 2019 · PeerJ
Nicotinamide: a vitamin able to shift macrophage differentiation toward macrophages with restricted inflammatory features
Weiss, Ronald, Schilling, Erik, Grahnert, Anja, Kölling, Valeen, Dorow, Juliane, Ceglarek, Uta, Sack, Ulrich, Hauschildt, Sunna · 2015 · Innate Immunity
SIRT1 links CIITA deacetylation to MHC II activation
Xiaoyan Wu, Xiaocen Kong, Dewei Chen, He Li, Yuhao Zhao, Minjie Xia, Mingming Fang, Ping Li, Fei Fang, Lina Sun et al. · 2011 · Nucleic Acids Research
The emergence of the nicotinamide riboside kinases in the regulation of NAD+ metabolism
Rachel S. Fletcher, Gareth Geoffrey Lavery · 2018 · Journal of Molecular Endocrinology
NAD+-consuming enzymes in immune defense against viral infection
Jialin Shang, Michael R. Smith, Ananya Anmangandla, Hening Lin · 2021 · Biochemical Journal
The role of caloric load and mitochondrial homeostasis in the regulation of the NLRP3 inflammasome
Javier Traba, Michael N. Sack · 2016 · Cellular and Molecular Life Sciences
Vitamin B3, the nicotinamide adenine dinucleotides and aging
Ping Xu, Anthony A. Sauve · 2010 · Mechanisms of Ageing and Development
Putative tumor suppression function of SIRT6 in endometrial cancer
Tomohiko Fukuda, Osamu Wada‐Hiraike, Katsutoshi Oda, Michihiro Tanikawa, Chinami Makii, Kanako Inaba, Aki Miyasaka, Yuichiro Miyamoto, Tetsu Yano, Daichi Maeda et al. · 2015 · FEBS Letters
Sirt6 regulates dendritic cell differentiation, maturation, and function
Denise Lasigliè, Silvia Boero, Inga Bauer, Sara Morando, Patrizia Damonte, Michele Cea, Fiammetta Monacelli, Paizio Odetti, Alberto Ballestrero, Antonio Uccelli et al. · 2016 · Aging
Nicotinamide mononucleotide alleviates Aluminum induced bone loss by inhibiting the TXNIP-NLRP3 inflammasome
Haipeng Liang, Jian Gao, Chi Zhang, Chunlin Li, Qi Wang, Jiaojiao Fan, Zizheng Wu, Qiugen Wang · 2018 · Toxicology and Applied Pharmacology
Nicotinamide adenine dinucleotide emerges as a therapeutic target in aging and ischemic conditions
Leila Hosseini, Manouchehr Seyedi Vafaee, Javad Mahmoudi, Reza Badalzadeh · 2019 · Biogerontology
Sirtuin 1 Is a Key Regulator of the Interleukin-12 p70/Interleukin-23 Balance in Human Dendritic Cells
Yolanda Álvarez, Mario Rodríguez Rodríguez, Cristina Municio, Etzel Hugo, Sara Alonso, Nieves Ibarrola, Nieves Fernández, Mariano Sánchez Crespo · 2012 · Journal of Biological Chemistry
Targeting Nicotinamide Phosphoribosyltransferase as a Potential Therapeutic Strategy to Restore Adult Neurogenesis
Shu‐Na Wang, Tian‐Ying Xu, Wenlin Li, Chao‐Yu Miao · 2016 · CNS Neuroscience & Therapeutics
Mast cells regulate CD4+ T-cell differentiation in the absence of antigen presentation
Héctor Rodríguez Cetina Biefer, Timm Heinbokel, Hirofumi Uehara, Virginia Camacho, Koichiro Minami, Yeqi Nian, Suresh Koduru, Rachid El Fatimy, Ionita Calin Ghiran, Alexander J. Trachtenberg et al. · 2018 · Journal of Allergy and Clinical Immunology
Nicotinamide phosphoribosyltransferase aggravates inflammation and promotes atherosclerosis in ApoE knockout mice
Yuanyuan Kong, Guoqiang Li, Wenjie Zhang, Xia Hua, Cancan Zhou, Tian‐Ying Xu, Zhiyong Li, Pei Wang, Chao‐Yu Miao · 2019 · Acta Pharmacologica Sinica
Visfatin is induced by peroxisome proliferator‐activated receptor gamma in human macrophages
Thérèse Hervèe Mayi, Christian Duhem, Corinne Copin, Mohamed Amine Bouhlel, Elena Rigamonti, François N. Pattou, Bart Staels, Giulia Chinetti · 2010 · FEBS Journal
Nicotinamide phosphoribosyltransferase/sirtuin 1 pathway is involved in human immunodeficiency virus type 1 Tat‐mediated long terminal repeat transactivation
Hongsheng Zhang, Wei‐Wei Sang, Yuou Wang, Wei Liu · 2010 · Journal of Cellular Biochemistry
Elevated visfatin levels in overweight and obese children and adolescents with metabolic syndrome
Magnhild L Pollestad Kolsgaard, Teresia Wangensteen, Cathrine Brunborg, Geir Joner, Kirsten Bjørklund Holven, Bente Lise Halvorsen, Pål Aukrust, Serena Tonstad · 2009 · Scandinavian Journal of Clinical and Laboratory Investigation
Nicotinamide Adenine Dinucleotide-Loaded Lubricated Hydrogel Microspheres with a Three-Pronged Approach Alleviate Age-Related Osteoarthritis
Yanpeng Lin, Hangtian Wu, Jun Wang, Wanling He, Jiahui Hou, Vidmi Taolam Martin, Chencheng Zhu, Yupeng Chen, Junyuan Zhong, Bin Yu et al. · 2025 · ACS Nano
The function of nicotinamide phosphoribosyl transferase (NAMPT) and its role in diseases
Aihong Peng, Junqin Li, Jianxiao Xing, Yuanjun Yao, Xuping Niu, Kaiming Zhang · 2024 · Frontiers in Molecular Biosciences
NAMPT and NAMPT-controlled NAD Metabolism in Vascular Repair
Pei Wang, Wenlin Li, Jianmin Liu, Chao‐Yu Miao · 2015 · Journal of Cardiovascular Pharmacology
Cytokines and pregnancy: Potential regulation by histone deacetylases
Sheryl K. Munro, Biju Balakrishnan, Abbey C Lissaman, Palak Gujral, Anna P. Ponnampalam · 2021 · Molecular Reproduction and Development
Sirtuin6 inhibits c‐triggered inflammation through TLR4 abrogation regulated by ROS and TRPV1/CGRP
Ruohua Zhang, Hongmin Li, Qin Guo, Lulu Zhang, Jie Zhu, Jin Ji · 2018 · Journal of Cellular Biochemistry
Ginsenosides Rc, as a novel SIRT6 activator, protects mice against high fat diet induced NAFLD
Zehong Yang, Yuanyuan Yu, Nannan Sun, Limian Zhou, Dong Zhang, Haixin Chen, Wei Miao, Weihang Gao, Can Yang Zhang, Changhui Liu et al. · 2020 · Journal of Ginseng Research
Effects of hyperglycemia and aging on nuclear sirtuins and DNA damage of mouse hepatocytes
Flávia G. Ghiraldini, Ana Carolina Vitolo Crispim, Maria Luiza S. Mello · 2013 · Molecular Biology of the Cell
Targeting of nicotinamide phosphoribosyltransferase enzymatic activity ameliorates lung damage induced by ischemia/reperfusion in rats
Geng-Chin Wu, Wen-I Liao, Shuyu Wu, Hsin‐Ping Pao, Shih-En Tang, Min‐Hui Li, Kun‐Lun Huang, Shi-Jye Chu · 2017 · Respiratory Research
Sirtuins and SIRT6 in Carcinogenesis and in Diet
Maria C. Teixeira, Elena Sánchez‐López, Marta Espina, Maria Luisa García, Alessandra Durazzo, Massimo Lucarini, Ettore Novellino, Selma B. Souto, Antonello Santini, Eliana B. Souto · 2019 · International Journal of Molecular Sciences
Serum visfatin and vaspin levels in hepatocellular carcinoma (HCC)
Monika Pazgan−Simon, Michał Kukla, Jolanta Zuwała−Jagiełło, Aleksandra Derra, Martyna Bator, Tomasz Menżyk, Andrzej Lekstan, Ewa Grzebyk, Krzysztof Adam Simon · 2020 · PLoS ONE
Scientometric Analysis of SIRT6 Studies
Kaining Lu, Shan Yu, Dan Sun, Haotian Xing, Jun An, Chuize Kong, Meng Yu, Yuyan Zhu · 2018 · Medical Science Monitor
Sirtuins 1–7 expression in human adipose-derived stem cells from subcutaneous and visceral fat depots: influence of obesity and hypoxia
Stefania Mariani, Giuliana Di Rocco, Gabriele Toietta, Matteo Antonio Russo, Elisa Petrangeli, Luisa Salvatori · 2016 · Endocrine
NAMPT: A potential prognostic and therapeutic biomarker in patients with glioblastoma
Qiuyun Guo, Na Han, Lei Shi, Li Yang, Xiaoxi Zhang, Yangmei Zhou, Shiying Yu, Mengxian Zhang · 2019 · Oncology Reports
The Role of Sirtuins in the Pathogenesis of Psoriasis
Sylwia Słuczanowska-Głąbowska, Maria Salmanowicz, Marzena Staniszewska, Andrzej Pawlik · 2023 · International Journal of Molecular Sciences
Intracellular NAD+ Depletion Confers a Priming Signal for NLRP3 Inflammasome Activation
Shim, Do-Wan, Cho, Hyo-Joung, Hwang, Inhwa, Jung, Taek-Yeol, Kim, Hyun-Seok, Ryu, Ju Hee, Yu, Je-Wook · 2021 · Frontiers in Immunology
Immunometabolism in Obese Asthmatics: Are We There Yet?
Hashim Periyalil, Peter G. Gibson, Lisa G. Wood · 2013 · Nutrients
A key role for Pre–B cell colony–enhancing factor in experimental hepatitis
Alexander Rupert Moschen, Romana Raphaela Gerner, Andrea Schroll, Teresa M.J. Fritz, Arthur Kaser, Herbert Tilg · 2011 · Hepatology
Neuroprotective Potential of Dendritic Cells and Sirtuins in Multiple Sclerosis
Francesco Piacente, Marta Bottero, Andrea Benzi, Tiziana Vigo, Antonio Uccelli, Santina Bruzzone, Giovanni Battista Ferrara · 2022 · International Journal of Molecular Sciences
Prognostic value of serum nicotinamide phosphoribosyltransferase in patients with bladder cancer
Kui Zhang, Bin Zhou, Peng Zhang, Zhu Zhang, Peng Chen, Yan Pu, Yaping Song, Lin Zhang · 2014 · Croatian Medical Journal
Involvement of visfatin in palmitate-induced upregulation of inflammatory cytokines in hepatocytes
Yong Jun Choi, Sung‐Eun Choi, Eun Suk Ha, YUP Y. KANG, Seung Jin Han, Dae Jung Kim, Kwan Woo Lee, Hae Jin Kim · 2011 · Metabolism
NAD+ Degrading Enzymes, Evidence for Roles During Infection
Arnold Tan, Craig L. Doig · 2021 · Frontiers in Molecular Biosciences
SIRT6 promotes metastasis and relapse in HER2-positive breast cancer
Cristina Andreani, Caterina Bartolacci, Giuseppe Persico, Francesca Casciaro, Stefano Amatori, Mirco Fanelli, Marco Giorgio, Mirco Galiè, Daniele Tomassoni, Junbiao Wang et al. · 2023 · Scientific Reports
Visfatin regulates the terminal processes of human labour and delivery via activation of the nuclear factor-κB pathway
Martha Lappas · 2011 · Molecular and Cellular Endocrinology
Expression of sirtuins 1, 6, tumor necrosis factor, and interferon-γ in psoriatic patients
H. Rasheed, Mohamed H.M. El-Komy, RA Hegazy, HI Gawdat, Aya M. AlOrbani, Olfat Gamil Shaker · 2016 · International Journal of Immunopathology and Pharmacology
The NAMPT enzyme employs a switch that directly senses AMP/ATP and regulates cellular responses to energy stress
Yumeng Zu, Chou Wu, Feifei Li, Hong Yao, Yu Xia, Ruoxi Zhang, Lulu Li, Shuangquan Chen, Qi Shi, Shuang Xi et al. · 2025 · Molecular Cell
Hypophosphatemia after Hepatectomy or Pancreatectomy: Role of the Nicotinamide Phosphoribosyltransferase
Jian Zheng, Ilya G. Glezerman, Eran Sadot, Anjuli McNeil, Cristina Zarama, Mithat Gönen, John M. Creasy, Linda M. Pak, Vinod P. Balachandran, Michael Ian D'Angelica et al. · 2017 · Journal of the American College of Surgeons
Serum sirtuin 1 levels in patients with polycystic ovary syndrome
Emel Kıyak Çağlayan, Yaprak Engin Üstün, Ayşe Yeşim Göçmen, Muhammet Fevzi Polat, Ayla Aktulay · 2014 · Journal of Obstetrics and Gynaecology
Nicotinamide enhances apoptosis of G(M)-CSF-treated neutrophils and attenuates endotoxin-induced airway inflammation in mice
Cláudia A. Fernandes, Laurence Fiévez, Bernard Učakar, Audrey M. Neyrinck, Catherine Fillée, François Huaux, Nathalie M. Delzenne, Fabrice Bureau, Rita Vanbever A · 2010 · American Journal of Physiology-Lung Cellular and Molecular Physiology
Prognostic impact of clinical course-specific mRNA expression profiles in the serum of perioperative patients with esophageal cancer in the ICU: a case control study
Shunsaku Takahashi, Norimasa Miura, Tomomi Harada, ZhongZhi Wang, Xinhui Wang, Hideyuki Tsubokura, Yoshiaki Oshima, Junichi Hasegawa, Yoshimi Inagaki, Goshi Shiota · 2010 · Journal of Translational Medicine
Inhibition of pre-B cell colony-enhancing factor (PBEF/NAMPT/visfatin) decreases the ability of human neutrophils to generate reactive oxidants but does not impair bacterial killing
Kate J Roberts, Andrew L. Cross, Olga Vasieva, Robert J. Moots, Steven W. Edwards · 2013 · Journal of Leukocyte Biology
PBEF/NAMPT/Visfatin: A Promising Drug Target For Treating Rheumatoid Arthritis?
Mari A. Nowell, Laura Evans, Anwen S. Williams · 2012 · Future Medicinal Chemistry
Is nuclear sirtuin SIRT6 a master regulator of immune function?
Vinodkumar B. Pillai, Mahesh P. Gupta · 2020 · American Journal of Physiology-Endocrinology and Metabolism
Nicotinamide breaks effector CD8 T cell responses by targeting mTOR signaling
Federica Agliano, Timofey A. Karginov, Antoine Ménoret, Anthony A. Provatas, Anthony T. Vella · 2022 · iScience
Regulation and Function of Extracellular Nicotinamide Phosphoribosyltransferase/Visfatin
Federico Carbone, Luca Liberale, Aldo Bonaventura, Alessandra Vecchié, Matteo Casula, Michele Cea, Fiammetta Monacelli, Irene Caffa, Santina Bruzzone, Fabrizio Montecucco et al. · 2017 · Comprehensive physiology
Potential Efficacy of Nutrient Supplements for Treatment or Prevention of COVID-19
Katrina L. Bogan-Brown, Yasmeen M. Nkrumah-Elie, Yusrah Ishtiaq, Philip Redpath, Andrew E. Shao · 2021 · Journal of Dietary Supplements
Endogenous NAMPT dampens chemokine expression and apoptotic responses in stressed tubular cells
Alberto Benito‐Martín, Alvaro Conrado Ucero, María Concepción Izquierdo, Beatriz Santamaría, Belén Picatoste, Susana Carrasco, Óscar Lorenzo, Marta Ruiz‐Ortega, Jesús Egido, Alberto Ortíz · 2013 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
A Novel Role for SIRT3 in Regulating Mediators Involved in the Terminal Pathways of Human Labor and Delivery
Ratana Lim, Gillian Barker, Ramkumar Menon, Martha Lappas · 2016 · Biology of Reproduction
Nicotinamide Phosphate Transferase (NAMPT) Increases in Plasma in Patients with Acute Coronary Syndromes, and Promotes Macrophages to M2 Polarization
Zhang, Chengxin, Zhu, Rui, Wang, Huiping, Tao, Qianshan, Lin, Xianhe, Ge, Shenglin, Zhai, Zhimin · 2018 · International Heart Journal
Association of SIRT6 circulating levels with urinary and glycometabolic markers in pre-diabetes and diabetes
Che Bian, Jing Gao, Yuxia Wang, Jia Li, Zhi‐Lin Luan, Heyuan Lu, Huiwen Ren · 2021 · Acta Diabetologica
mTOR regulation of metabolism limits LPS-induced monocyte inflammatory and procoagulant responses
Nina C. Lund, Yetunde I. Kayode, Melanie R. McReynolds, Deanna C. Clemmer, Hannah Hudson, Isabelle Clerc, Hee‐Kyung Hong, Jason M. Brenchley, Joseph T. Bass, Richard T. D’Aquila et al. · 2022 · Communications Biology
NAMPT inhibition relieves intestinal inflammation by regulating macrophage activation in experimental necrotizing enterocolitis
Qianyang Liu, Kai Gao, Xionghui Ding, Dandan Mo, Hongjie Guo, Bailin Chen, Bingshan Xia, Cuilian Ye, Gongli Chen, Chunbao Guo · 2023 · Biomedicine & Pharmacotherapy
The role of mammalian Sirtuin 6 in cardiovascular diseases and diabetes mellitus
Kehan Wu, Yaqiao Wang, Runmin Liu, Hao Wang, Rui Tao · 2023 · Frontiers in Physiology
Transcriptomic Analysis and Functional Characterization Reveal the Duck Interferon Regulatory Factor 1 as an Important Restriction Factor in the Replication of Tembusu Virus
Chengwei Xiang, Mei Huang, Ting Xiong, Fang Rong, Linyu Li, Ding Xiang Liu, Ruiai Chen · 2020 · Frontiers in Microbiology
Aging-related inflammation driven by cellular senescence enhances NAD consumption via activation of CD38 + pro-inflammatory macrophages
2019
Nicotinamide Prevents Diabetic Brain Inflammation via NAD+-Dependent Deacetylation Mechanisms
Jeimy Katherine Torres-Méndez, Julia Niño-Narvión, Patricia Martinez-Santos, Elena M. G. Diarte‐Añazco, Karen Alejandra Méndez‐Lara, Tania Vázquez del Olmo, Noemí Rotllán, María Teresa Julián, Núria Alonso, Dı́dac Mauricio et al. · 2023 · Nutrients