Regulation of hepatic innate immunity by hepatitis C virus

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Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance

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Identification and Characterization of MAVS, a Mitochondrial Antiviral Signaling Protein that Activates NF-κB and IRF3

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A diverse range of gene products are effectors of the type I interferon antiviral response

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Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

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Genetic variation in IL28B and spontaneous clearance of hepatitis C virus

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Genome-wide association of IL28B with response to pegylated interferon-α and ribavirin therapy for chronic hepatitis C

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Immune Signaling by RIG-I-like Receptors

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IL28B is associated with response to chronic hepatitis C interferon-α and ribavirin therapy

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TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity

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The global burden of hepatitis C

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Interferon-stimulated genes and their antiviral effector functions

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Innate immunity to virus infection

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Genomic analysis of the host response to hepatitis C virus infection

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Genetic Variation in IL28B Is Associated With Chronic Hepatitis C and Treatment Failure: A Genome-Wide Association Study

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Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF

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A variant upstream of IFNL3 (IL28B) creating a new interferon gene IFNL4 is associated with impaired clearance of hepatitis C virus

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Functional classification of interferon-stimulated genes identified using microarrays

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Regulating Intracellular Antiviral Defense and Permissiveness to Hepatitis C Virus RNA Replication through a Cellular RNA Helicase, RIG-I

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Genetic diversity and evolution of hepatitis C virus – 15 years on

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Peroxisomes are signaling platforms for antiviral innate immunity

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Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity

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Evidence That Hepatitis C Virus Resistance to Interferon Is Mediated through Repression of the PKR Protein Kinase by the Nonstructural 5A Protein

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Treatment of Acute Hepatitis C with Interferon Alfa-2b

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Regulation of Interferon Regulatory Factor-3 by the Hepatitis C Virus Serine Protease

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IFN-Lambda (IFN-λ) Is Expressed in a Tissue-Dependent Fashion and Primarily Acts on Epithelial Cells In Vivo

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Adaptive immune responses in acute and chronic hepatitis C virus infection

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Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA

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Regulation of innate antiviral defenses through a shared repressor domain in RIG-I and LGP2

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Inhibition of the Interferon- Inducible Protein Kinase PKR by HCV E2 Protein

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Interferon signaling and treatment outcome in chronic hepatitis C

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Toll‐like receptors and adaptor molecules in liver disease: Update†

Seki, E., & Brenner, D. A. (2008) · Hepatology · doi:10.1002/hep.22306 · Cited by 722 · see citing works

Control of PKR Protein Kinase by Hepatitis C Virus Nonstructural 5A Protein: Molecular Mechanisms of Kinase Regulation

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Distinct Patterns of IFITM-Mediated Restriction of Filoviruses, SARS Coronavirus, and Influenza A Virus

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Interferons α and λ Inhibit Hepatitis C Virus Replication With Distinct Signal Transduction and Gene Regulation Kinetics

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Control of antiviral defenses through hepatitis C virus disruption of retinoic acid-inducible gene-I signaling

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Mitochondrial-associated endoplasmic reticulum membranes (MAM) form innate immune synapses and are targeted by hepatitis C virus

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IFIT1 is an antiviral protein that recognizes 5′-triphosphate RNA

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TLR3 Can Directly Trigger Apoptosis in Human Cancer Cells

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The autophagy machinery is required to initiate hepatitis C virus replication

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Pathogenesis of chronic viral hepatitis: differential roles of T cells and NK cells

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Structural basis of RNA recognition and activation by innate immune receptor RIG-I

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IL-1β Production through the NLRP3 Inflammasome by Hepatic Macrophages Links Hepatitis C Virus Infection with Liver Inflammation and Disease

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Hepatic ISG Expression Is Associated With Genetic Variation in Interleukin 28B and the Outcome of IFN Therapy for Chronic Hepatitis C

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Viral and therapeutic control of IFN-β promoter stimulator 1 during hepatitis C virus infection

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DDX1, DDX21, and DHX36 Helicases Form a Complex with the Adaptor Molecule TRIF to Sense dsRNA in Dendritic Cells

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IL28B Genotype Is Associated With Differential Expression of Intrahepatic Interferon-Stimulated Genes in Patients With Chronic Hepatitis C

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The history of the "fast sound" in liquid water

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Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: role of IRF‐1 and NF‐κB

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Disruption of innate immunity due to mitochondrial targeting of a picornaviral protease precursor

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Identification of Three Interferon-Inducible Cellular Enzymes That Inhibit the Replication of Hepatitis C Virus

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Antiviral strategies in hepatitis C virus infection

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Plasmacytoid dendritic cells sense hepatitis C virus–infected cells, produce interferon, and inhibit infection

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HCV Infection Induces a Unique Hepatic Innate Immune Response Associated With Robust Production of Type III Interferons

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Interferon-Induced Gene Expression Is a Stronger Predictor of Treatment Response Than IL28B Genotype in Patients With Hepatitis C

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The history of the “natural history” of hepatitis C (1968–2009)

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Alpha Interferon Induces Distinct Translational Control Programs To Suppress Hepatitis C Virus RNA Replication

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Analysis of ISG Expression in Chronic Hepatitis C Identifies Viperin as a Potential Antiviral Effector *

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Hepatitis C Virus Blocks Interferon Effector Function by Inducing Protein Kinase R Phosphorylation

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IPS-1 Is Essential for the Control of West Nile Virus Infection and Immunity

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Dissociation of a MAVS/IPS-1/VISA/Cardif-IKKε Molecular Complex from the Mitochondrial Outer Membrane by Hepatitis C Virus NS3-4A Proteolytic Cleavage

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Variants in IL28B in Liver Recipients and Donors Correlate With Response to Peg-Interferon and Ribavirin Therapy for Recurrent Hepatitis C

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The antiviral protein viperin inhibits hepatitis C virus replication via interaction with nonstructural protein 5A

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Toll-Like Receptor 3 Mediates Establishment of an Antiviral State against Hepatitis C Virus in Hepatoma Cells

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The Mitochondrial Targeting Chaperone 14-3-3ε Regulates a RIG-I Translocon that Mediates Membrane Association and Innate Antiviral Immunity

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IL28B expression depends on a novel TT/-G polymorphism which improves HCV clearance prediction

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Activation of chemokine and inflammatory cytokine response in hepatitis C virus–infected hepatocytes depends on toll-like receptor 3 sensing of hepatitis C virus double-stranded RNA intermediates

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Hepatitis C Virus Particles and Lipoprotein Metabolism

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New Therapies for Hepatitis C Virus Infection

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Hepatitis C virus induces interferon-λ and interferon-stimulated genes in primary liver cultures

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IFN-Induced TPR Protein IFIT3 Potentiates Antiviral Signaling by Bridging MAVS and TBK1

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IFITm1 Is a Tight Junction Protein That Inhibits Hepatitis C Virus Entry

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MAVS Dimer Is a Crucial Signaling Component of Innate Immunity and the Target of Hepatitis C Virus NS3/4A Protease

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Nucleotide Sequences and Modifications That Determine RIG-I/RNA Binding and Signaling Activities

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Interferon-lambda serum levels in hepatitis C

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ISG56 and IFITM1 Proteins Inhibit Hepatitis C Virus Replication

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Identification of type I and type II interferon-induced effectors controlling hepatitis C virus replication

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Nonstructural protein 3‐4A: the Swiss army knife of hepatitis C virus

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3′ RNA Elements in Hepatitis C Virus Replication: Kissing Partners and Long Poly(U)

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GB Virus B Disrupts RIG-I Signaling by NS3/4A-Mediated Cleavage of the Adaptor Protein MAVS

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Expressional screening of interferon‐stimulated genes for antiviral activity against hepatitis C virus replication

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