Self-renewal as a therapeutic target in human colorectal cancer

Kreso, Antonija, van Galen, Peter, Pedley, Nicholas M, Lima-Fernandes, Evelyne, Frelin, Catherine, Davis, Thomas, Cao, Liangxian, Baiazitov, Ramil +12 more·2014·Nature Medicine

DOI 10.1038/nm.3418

Cited by (502)

Items 101–200 of 502

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Tao Wang, Hong Wu, Sha Liu, Zengjie Lei, Zhong‐yi Qin, Liangzhi Wen, Kaijun Liu, Xingwei Wang, Yan Guo, Qin Liu et al. · 2018 · Cancer Letters
Cancer stem cells in human digestive tract malignancies
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Jinwei Hu, Saied Mirshahidi, Alfred Simental, Steve C. Lee, Pedro Andrade Filho, Nathaniel R. Peterson, Penelope J. Duerksen-Hughes, Xiangpeng Yuan · 2019 · Oncogene
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BMI-1 Targeting Interferes with Patient-Derived Tumor-Initiating Cell Survival and Tumor Growth in Prostate Cancer
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Upasana Kapoor-Narula, Nibedita Lenka · 2022 · Cytokine
Pyrvinium Targets CD133 in Human Glioblastoma Brain Tumor–Initiating Cells
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Andrew T. Fesler, Hua Liu, Jingfang Ju · 2017 · Oncotarget
Targeting of BMI-1 with PTC-209 shows potent anti-myeloma activity and impairs the tumour microenvironment
Arnold Bolomsky, Karin Schlangen, Wolfgang Schreiner, Niklas Zojer, Heinz Ludwig · 2016 · Journal of Hematology & Oncology
Epigenetic regulation of cancer stemness
Claudia Galassi, Gwenola Manic, Manel Esteller, Lorenzo Galluzzi, Ilio Vitale · 2025 · Signal Transduction and Targeted Therapy
MUC1-C activates BMI1 in human cancer cells
Masayuki Hiraki, Takahiro Maeda, Audrey Bouillez, M Alam, Ashujit Tagde, Kunihiko Hinohara, Yozo Suzuki, Tahireh Markert, Masaaki Miyo, K Komura et al. · 2016 · Oncogene
Super-Enhancers, Phase-Separated Condensates, and 3D Genome Organization in Cancer
S. Tang, Udhaya Vijayakumar, Ying Zhang, M. Fullwood · 2022 · Cancers
Nuclear-encoded cytochrome c oxidase subunit 4 regulates BMI1 expression and determines proliferative capacity of high-grade gliomas
Claudia R. Oliva, Tahireh Markert, G. Yancey Gillespie, Corinne E. Griguer · 2015 · Oncotarget
Targeting self-renewal, an Achilles' heel of cancer stem cells
Max S. Wicha · 2014 · Nature Medicine
Bladder Cancer Stem-Like Cells: Their Origin and Therapeutic Perspectives
Tomokazu Ohishi, Fumitaka Koga, Toshiro Migita · 2015 · International Journal of Molecular Sciences
Polycomb complex protein BMI-1 promotes invasion and metastasis of pancreatic cancer stem cells by activating PI3K/AKT signaling, an ex vivo, in vitro, and in vivo study
Mincong Wang, Min Jiao, Tao Wu, Jing Li, Jie Cui, Hui Guo, Tao Tian, Zhiping Ruan, Yongchang Wei, Lili Jiang et al. · 2016 · Oncotarget
Current understanding and clinical utility of miRNAs regulation of colon cancer stem cells
Mariangela De Robertis, Maria Luana Poeta, Emanuela Signori, Vito Michele Fazio · 2018 · Seminars in Cancer Biology
The Crucial Roles of Bmi-1 in Cancer: Implications in Pathogenesis, Metastasis, Drug Resistance, and Targeted Therapies
Jie Xu, Lin Li, Pengfei Shi, Hongjuan Cui, Liqun Yang · 2022 · International Journal of Molecular Sciences
Advances in targeted and immunobased therapies for colorectal cancer in the genomic era
Heng Fong Seow, Wai Kien Yip, Theodora Fifis · 2016 · OncoTargets and Therapy
Downregulation of Bmi1 in breast cancer stem cells suppresses tumor growth and proliferation
Mathangi Srinivasan, Dhruba Jyoti Bharali, Thangirala Sudha, Maha Khedr, Ian Guest, Stewart Sell, Gennadi V. Glinsky, Shaker A. Mousa · 2017 · Oncotarget
The standardized Korean Red Ginseng extract and its ingredient ginsenoside Rg3 inhibit manifestation of breast cancer stem cell–like properties through modulation of self-renewal signaling
Jisun Oh, Hyo‐Jin Yoon, Jeong‐Hoon Jang, Do‐Hee Kim, Young‐Joon Surh · 2018 · Journal of Ginseng Research
Targeted BMI1 inhibition impairs tumor growth in lung adenocarcinomas with low CEBPα expression
Kol Jia Yong, Daniela S. Daniela Sanchez Bassères, Robert S. Welner, Wen Cai Zhang, Henry He Yang, Benedict Yan, Meritxell Alberich-Jordà, Junyan Zhang, Lorena Lobo de Figueiredo‐Pontes, Chiara Battelli et al. · 2016 · Science Translational Medicine
Targeting bivalency de-represses Indian Hedgehog and inhibits self-renewal of colorectal cancer-initiating cells
Lima-Fernandes, Evelyne, Murison, Alex, da Silva Medina, Tiago, Wang, Yadong, Ma, Anqi, Leung, Cherry, Luciani, Genna M., Haynes, Jennifer, Pollett, Aaron, Zeller, Constanze et al. · 2019 · Nature Communications
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Tal Shasha, Mandy Gruijs, Marjolein van Egmond · 2022 · Cellular and Molecular Life Sciences
SOX9-regulated cell plasticity in colorectal metastasis is attenuated by rapamycin
Estefanía Carrasco‐García, Lidia Lopez, Paula Aldaz, Sara Arévalo, Juncal Aldaregia, Larraitz Egaña, Luís Bujanda, Martin C. H. Cheung, Nicolàs Samprón, Idoia García et al. · 2016 · Scientific Reports
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Shaheedul A. Sami, Noureldien H. E. Darwish, Amanda N. M. Barile, Shaker A. Mousa · 2020 · Current Treatment Options in Oncology
Genome-wide mutation profiles of colorectal tumors and associated liver metastases at the exome and transcriptome levels
Byungho Lim, Jihyeob Mun, Jeong‐Hwan Kim, Chan Wook Kim, Seon Ae Roh, Dong‐Hyung Cho, Seon‐Young Kim, Seon‐Young Kim, Jin Cheon Kim · 2015 · Oncotarget
The miR‐200b–ZEB1 circuit regulates diverse stemness of human hepatocellular carcinoma
Shu‐Chun Tsai, Chen‐Chun Lin, Tsung‐Chieh Shih, R.-Y. Tseng, Ming‐Chin Yu, Yu‐Jr Lin, Sen‐Yung Hsieh · 2017 · Molecular Carcinogenesis
G9a controls pluripotent-like identity and tumor-initiating function in human colorectal cancer
Christopher J. Bergin, Aïcha Zouggar, Joshua R. Haebe, Angelique N. Masibag, François M. Desrochers, Simon Y. Reilley, Gautam Agrawal, Yannick D. Benoit · 2020 · Oncogene
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Reduction of gastric cancer proliferation and invasion by miR-15a mediated suppression of Bmi-1 translation
Changping Wu, Xiao Wei Zheng, Xiaodong Li, Andrew T. Fesler, Wenwei Hu, Lujun Chen, Bin Xu, Qi Wang, Anthony Tong, Stephanie Burke et al. · 2016 · Oncotarget
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Cancer Stem Cells: Constantly Evolving and Functionally Heterogeneous Therapeutic Targets
Tao Yang, Kiera Rycaj, Zhong-Min Liu, Dean G. Tang · 2014 · Cancer Research
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Qiong Wang, Zhongwu Li, Yaping Wu, Rong Huang, Yumin Zhu, Wei Zhang, Yanling Wang, Jie Cheng · 2017 · Cancer Cell International
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