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Supercooling enables long-term transplantation survival following 4 days of liver preservation

Open access
Berendsen, Tim A, Bruinsma, Bote G, Puts, Catheleyne F, Saeidi, Nima, Usta, O Berk, Uygun, Basak E, Izamis, Maria-Louisa, Toner, Mehmet, Yarmush, Martin L, Uygun, Korkut·2014·Nature Medicine

Abstract

The realization of long-term human organ preservation will have groundbreaking effects on the current practice of transplantation. Herein we present a new technique based on subzero nonfreezing preservation and extracorporeal machine perfusion that allows transplantation of rat livers preserved for up to four days, thereby tripling the viable preservation duration.

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Metadata

Authors
Berendsen, T. A., Bruinsma, B. G., Puts, C. F., Saeidi, N., Usta, O. B., Uygun, B. E., Izamis, M.-L., Toner, M., Yarmush, M. L., & Uygun, K.
Venue
Nature Medicine
Published
2014-06-29
Volume
20
Issue
7
Pages
790-793
ISSN
  • 1078-8956 (ISSN-L)
  • 1546-170X
OpenAlex
W1995195785
Cited by
205
References
0
FWCI
11.35
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Supercooling enables long-term transplantation survival following 4 days of liver preservation. https://app.cochat.ai/papers/10.1038/nm.3588
The paper
Berendsen, T. A., Bruinsma, B. G., Puts, C. F., Saeidi, N., Usta, O. B., Uygun, B. E., Izamis, M.-L., Toner, M., Yarmush, M. L., & Uygun, K. (2014). Supercooling enables long-term transplantation survival following 4 days of liver preservation. Nature Medicine. https://doi.org/10.1038/nm.3588

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.