Two FOXP3+CD4+ T cell subpopulations distinctly control the prognosis of colorectal cancers

Saito, Takuro, Nishikawa, Hiroyoshi, Wada, Hisashi, Nagano, Yuji, Sugiyama, Daisuke, Atarashi, Koji, Maeda, Yuka, Hamaguchi, Masahide +14 more·2016·Nature Medicine

Cited by (874)

Items 501–600 of 874

  1. Tumor Microenvironment Characterization in Breast Cancer Identifies Prognostic Pathway Signatures
    Ji Li, Jiayue Qiu, Junwei Han, Xiangmei Li, Ying Jiang · 2022 · Genes
  2. CXCL11 negatively regulated by MED19 favours antitumour immune infiltration in breast cancer
    Xiufen Zhang, Junqiang Wu, Caixia Hu, Xiaoyuan Zheng, Zijian Guo, Lihua Li · 2022 · Cytokine
  3. Human regulatory T cells (Treg) and their response to cancer
    Theresa L. Whiteside · 2019 · Expert Review of Precision Medicine and Drug Development
  4. Immunophenotyping of Human Regulatory T Cells
    Janet S. Staats · 2019 · Methods in molecular biology
  5. Janus or Hydra: The Many Faces of T Helper Cells in the Human Tumour Microenvironment
    Florian Guisier, Mateus Camargo Barros‐Filho, Leigha D. Rock, Megan Rae Strachan-Whaley, Erin A. Marshall, Graham Dellaire, Wan L. Lam · 2020 · Advances in experimental medicine and biology
  6. Regulatory T cells in liver metastases: emerging and divergent roles in tumour progression
    Grace Wu, Ti Yang, Sepideh Gholami, Danielle K. DePeralta, Matthew John Weiss, Meihong Deng, Ping Wang, Hai Huang · 2025 · eGastroenterology
  7. Single-cell and spatial transcriptomic analysis reveals tumor cell heterogeneity and underlying molecular program in colorectal cancer
    Teng Wang, Zhaoming Chen, Wang Wang, Heng Wang, Shenglong Li · 2025 · Frontiers in Immunology
  8. Cancer Immunotherapies Targeting Tumor-Associated Regulatory T Cells
    Xiaoxu Ge, Yamei Zhao, Chao Chen, Jian Wang, Lifeng Sun · 2019 · OncoTargets and Therapy
  9. CD163+ macrophages suppress T cell response by producing TGF-β in pediatric colorectal polyps
    Shun-Xian Zhang, Xiaoqin Li, Li Zhu, Siqi Ming, Hongli Wang, Jing Xie, Lu Ren, Jing Huang, Defeng Liang, Liya Xiong et al. · 2021 · International Immunopharmacology
  10. Biomarkers of Favorable vs. Unfavorable Responses in Locally Advanced Rectal Cancer Patients Receiving Neoadjuvant Concurrent Chemoradiotherapy
    Hsin-Hua Lee, Chien‐Hung Chen, Yu-Hsiang Huang, Cheng-Han Chiang, Ming‐Yii Huang · 2022 · Cells
  11. Targeting Epigenetic Mechanisms: A Boon for Cancer Immunotherapy
    Asmita Parab, Lokesh Kumar Bhatt, Abdelwahab Omri · 2023 · Biomedicines
  12. Downregulation of miR-4772-3p promotes enhanced regulatory T cell capacity in malignant pleural effusion by elevating Helios levels
    Wenqing Yu, Ningfei Ji, Chengjing Gu, Zhixiao Sun, Zhengxia Wang, Zhongqi Chen, Yuan Ma, Zhenzhen Wu, Yanli Wang, Chaojie Wu et al. · 2019 · Chinese Medical Journal
  13. Immune Profiling of Deficient Mismatch Repair Colorectal Cancer Tumor Microenvironment Reveals Different Levels of Immune System Activation
    Riccardo Giannini, Gemma Zucchelli, Mirella Giordano, Clara Ugolini, Roberto Moretto, Katarzyna E. Ambryszewska, Michele Leonardi, Elisa Sensi, Federica Morano, Filippo Pietrantonio et al. · 2020 · Journal of Molecular Diagnostics
  14. Prognostic and predictive significance of the tumor microenvironment in hepatocellular carcinoma
    Jibing Liu, Shuwen Kuang, Yiling Zheng, Mei Liu, Liming Wang · 2021 · Cancer Biomarkers
  15. Single-cell atlas of the esophageal squamous cell carcinoma immune ecosystem to predict immunotherapy response
    Xiankai Chen, Yahui Zhao, Yuhao Wang, Xiliang Wang, Yuhao Liu, Zhihua Liu, Yin Li · 2025 · Signal Transduction and Targeted Therapy
  16. Oral Microbiota and Carcinogenesis: Exploring the Systemic Impact of Oral Pathogens
    Nadja Nikolić, Ana Pucar, Uroš Tomić, Sanja Petrović, Đorđe Mihailović, Aleksandar Jovanović, Milena Radunović · 2025 · Pathogens
  17. Role of ubiquitin specific proteases in the immune microenvironment of prostate cancer: A new direction
    Jinhui Guo, Jie Zhao, Litao Sun, Yang Chen · 2022 · Frontiers in Oncology
  18. Cancer‐Specific RNA Modifications in Tumour‐Derived Extracellular Vesicles Promote Tumour Growth
    Yuya Monoe, Kentaro Jingushi, Kohei Taniguchi, Kensuke Hirosuna, Jun Arima, Yosuke Inomata, Yoshiaki Takano, Hiroki Hamamoto, Kazumasa Komura, Tomohito Tanaka et al. · 2025 · Journal of Extracellular Vesicles
  19. Survival Advantage Following TAG-72 Antigen-Directed Cancer Surgery in Patients With Colorectal Carcinoma: Proposed Mechanisms of Action
    Charles L. Hitchcock, Stephen P. Povoski, Cathy M. Mojzisik, Edward W. Martin · 2021 · Frontiers in Oncology
  20. Immune Infiltration Characteristics and a Gene Prognostic Signature Associated With the Immune Infiltration in Head and Neck Squamous Cell Carcinoma
    Chunmei Zhu, Qiuji Wu, Ningning Yang, Zhewen Zheng, Fuxiang Zhou, Yunfeng Zhou · 2022 · Frontiers in Genetics
  21. AHCYL1 Is a Novel Biomarker for Predicting Prognosis and Immunotherapy Response in Colorectal Cancer
    Xubin Li, Mengqiao Zhang, Yu Xue, Mei Xue, Xiaowei Li, Chao Ma, Wei Jia, Qiang Gao, Chunbo Kang · 2022 · Journal of Oncology
  22. Exosomes in metastasis of colorectal cancers: Friends or foes?
    Zheng Qun Wu, Ze-Xuan Fang, Yan-Yu Hou, Bingxuan Wu, Yu Deng, Hua-Tao Wu, Jing Liu · 2023 · World Journal of Gastrointestinal Oncology
  23. The Prognostic Value of Tumor Infiltrating Lymphocytes After Radical Cystectomy for Bladder Cancer: A Systematic Review and Meta-Analysis
    Tatsushi Kawada, Takafumi Yanagisawa, Paweł Rajwa, Reza Sari Motlagh, Hadi Mostafaei, Fahad Quhal, Ekaterina Laukhtina, Maximilian Pallauf, Frederik König, Benjamin Pradère et al. · 2024 · Clinical Genitourinary Cancer
  24. Evaluation of regulatory T-cells in cancer immunotherapy: therapeutic relevance of immune checkpoint inhibition
    Ranjeet Kumar Singh, Prateek Srivastava, Partha Pratim Manna · 2024 · Medical Oncology
  25. Immune cell expression of TGFβ1 in cancer with lymphoid stroma: dendritic cell and regulatory T cell contact
    Haruo Ohtani, Toru Terashima, Eiichi Sato · 2018 · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin
  26. Postoperative ratio of the maximum C-reactive protein level to the minimum peripheral lymphocyte count as a prognostic indicator for gastric cancer patients
    Yusuke Kono, Hiroaki Saito, Yuki Murakami, Yuji Shishido, Hirohiko Kuroda, Tomoyuki Matsunaga, Manabu Yamamoto, Yoji Fukumoto, Tomohiro Osaki, Keigo Ashida et al. · 2018 · Surgery Today
  27. Regulatory T Cells and Their Clinical Applications in Antitumor Immunotherapy
    Feng Xie, Rui Liang, Dan Li, Bin Li · 2018 · Engineering
  28. Therapy with CD4+CD25+ T regulatory cells – should we be afraid of cancer?
    Mateusz Gliwiński, Magdalena Piotrowska, Dorota Iwaszkiewicz‐Grześ, Zuzanna Urban‐Wójciuk, Piotr Trzonkowski · 2019 · Współczesna Onkologia
  29. BACH2 regulates the function of human CD4 + CD45RA − Foxp3 l ° cytokine‐secreting T cells and promotes B‐cell response in systemic lupus erythematosus
    Yingxia Zheng, Yiwen Lu, Xinfang Huang, Han Li, Zheyi Chen, Bingqian Zhou, Yanhui Ma, Guohua Xie, Junyao Yang, Bingxian Bian et al. · 2019 · European Journal of Immunology
  30. Immunohistochemical distribution of FOXP3+ regulatory T cells in colorectal cancer patients.
    Zhian Ling, Lijie Zhang, Zhihua Ye, Yi‐Wu Dang, Gang Chen, Ruolin Li, Jingjing Zeng · 2018 · PubMed Central
  31. Immunobiology of Melanoma
    Yee Peng Phoon, Charles S. Tannenbaum, Claudia Marcela Diaz-Montero · 2021 · Clinics in Plastic Surgery
  32. Collagen I enhances the efficiency and anti-tumor activity of dendritic-tumor fusion cells
    Jian He, Rong Zheng, Zhenghua Zhang, Jie Tan, Chaofan Zhou, Guoqing Zhang, Xinglu Jiang, Qianyi Sun, Sufang Zhou, Duo Zheng et al. · 2017 · OncoImmunology
  33. The potential application of PD-1 blockade therapy for early-stage biliary tract cancer
    Kumiko Umemoto, Yosuke Togashi, Yasuhito Arai, Hiromi K. Nakamura, Shinichiro Takahashi, Tokiyoshi Tanegashima, Mikiya Kato, Tsubasa Nishikawa, Daisuke Sugiyama, Motohiro Kojima et al. · 2019 · International Immunology
  34. Immune signatures of the POLE mutation in endometrial carcinomas: a systematic study based on TCGA data and clinical cohort validation
    Tieyan Wang, Dan Yu, Juanjuan Wang, Ningning Zhu, Xian-bin Tang, Xiuwen Chen, Lei Su, Yugang Huang · 2023 · Frontiers in Oncology
  35. Advances in tumor immune microenvironment of head and neck squamous cell carcinoma: A review of literature
    Qichao Hong, Shun Ding, Chengliang Xing, Zhonglin Mu · 2024 · Medicine
  36. Dysbiosis of the gut microbiome may contribute to the pathogenesis of oral lichen planus through Treg dysregulation
    Shiho Yokomizo, Naoki Kaneko, Hu Chen, Lijing Yan, Shoji Tsuji, Shohei Akagawa, Junsei Sameshima, Tomoki Sueyoshi, Haruki Nagano, Yuka Miyahara et al. · 2025 · Mucosal Immunology
  37. Non-immune Cell Components in the Gastrointestinal Tumor Microenvironment Influencing Tumor Immunotherapy
    Zhengshuo Li, Xiaoyue Zhang, Can Liu, Jian Ma · 2021 · Frontiers in Cell and Developmental Biology
  38. Computational Recognition of a Regulatory T-cell-specific Signature With Potential Implications in Prognosis, Immunotherapy, and Therapeutic Resistance of Prostate Cancer
    Mingyi Ju, Jingyi Fan, Yuanjiang Zou, Mingjie Yu, Longyang Jiang, Qian Wei, Jia Bi, Baohui Hu, Qiutong Guan, Xinyue Song et al. · 2022 · Frontiers in Immunology
  39. Global research on the crosstalk between intestinal microbiome and colorectal cancer: A visualization analysis
    Shanshan Yang, Shaodong Hao, Hui Ye, Xuezhi Zhang · 2023 · Frontiers in Cellular and Infection Microbiology
  40. CD204⁺ tumor-associated macrophages are associated with clinical outcome in canine pulmonary adenocarcinoma and transitional cell carcinoma
    S. Yokota, K. Kaji, Tomohiro Yonezawa, Yasuyuki Momoi, Shingo Maeda · 2023 · The Veterinary Journal
  41. Suppression from beyond the grave
    Yosuke Togashi, Hiroyoshi Nishikawa · 2017 · Nature Immunology
  42. Involvement of MAF1�homolog, negative regulator of RNA polymerase�III in colorectal cancer progression
    Kentaro Hokonohara, Naohiro Nishida, Norikatsu Miyoshi, Hidekazu Takahashi, Naotsugu Haraguchi, Taishi Hata, Chu Matsuda, Tsunekazu Mizushima, Yuichiro� Doki, Masaki Mori · 2019 · International Journal of Oncology
  43. Regulatory T cells reduce endothelial neutral sphingomyelinase 2 to prevent T‐cell migration into tumors
    Paulina Akéus, Louis Szeponik, Veronica Langenes, Viktoria Karlsson, Patrik Sundström, Elinor Bexe Lindskog, Carolyn Tallon, Barbara Stauch Slusher, Marianne Quiding‐Järbrink · 2021 · European Journal of Immunology
  44. A study on the correlation between M2 macrophages and regulatory T cells in the progression of colorectal cancer
    Yanlei Chen, Yu Jie Gao, Xueqian Ma, Yanping Wang, Jinhao Liu, Chunyu Yang, Yue Wang, Cuifen Bao, Xiaoyu Song, Yang Feng et al. · 2022 · The International Journal of Biological Markers
  45. How the Tumor Micromilieu Modulates the Recruitment and Activation of Colorectal Cancer-Infiltrating Lymphocytes
    Imke Atreya, Markus Friedrich Neurath · 2022 · Biomedicines
  46. Interleukin‐23 receptor defines T helper 1‐like regulatory T cells in oral squamous cell carcinoma
    Wei Li, Ning An, Ming‐Wei Wang, Xiguo Liu, Zhidan Mei · 2022 · Immunity Inflammation and Disease
  47. Prediction of immunotherapy efficacy and immunomodulatory role of hypoxia in colorectal cancer
    Zhuangzhuang Zheng, Chenbin Bian, Huanhuan Wang, Jing Su, Lingbin Meng, Ying Xin, Xin Mei Jiang · 2022 · Therapeutic Advances in Medical Oncology
  48. Small molecule inhibitors targeting regulatory T cells for cancer treatment
    Nuria García‐Díaz, Qian Wei, Kjetil Taskén · 2023 · European Journal of Immunology
  49. Immune cell infiltrates in peritoneal metastases from colorectal cancer
    Patrik Sundström, Stephen Hogg, Marianne Quiding‐Järbrink, Elinor Bexe Lindskog · 2024 · Frontiers in Immunology
  50. The tumor-stroma ratio in giant cell tumor of bone: associations with the immune microenvironment and responsiveness to denosumab treatment
    Hailin Wu, Xiao-Bin Wang, Jing Li, Bo‐Wen Zheng · 2024 · Journal of Orthopaedic Surgery and Research
  51. Molecular hydrogen has a positive impact on pregnancy maintenance through enhancement of mitochondrial function and immunomodulatory effects on T cells
    Chieko Aoki, Kenji Imai, Teruyuki Mizutani, Daisuke Sugiyama, Rika Miki, Yoshihiro Koya, Tomoko Kobayashi, Takafumi Ushida, Yukako Iitani, Noriyuki Nakamura et al. · 2022 · Life Sciences
  52. Vascular endothelial growth factor inhibitors promote antitumor responses via tumor microenvironment immunosuppression in advanced colorectal cancer
    Yuki Hamada, Kiyonori Tanoue, Yoshiaki Kita, Kan Tanabe, Kentaro Hokonohara, Masumi Wada, Yuto Hozaka, Hideyuki Oi, Chieri Nakayama, Michiyo Higashi et al. · 2023 · Scandinavian Journal of Gastroenterology
  53. The possible anti-tumor effects of regulatory T cells plasticity / IL-35 in the tumor microenvironment of the major three cancer types
    Rehab G. Khalil, Dina A. Mohammed, Hadeer Mohamed Hamdalla, Osama M. Ahmed · 2024 · Cytokine
  54. Immune biomarkers for predicting response to adoptive cell transfer as cancer treatment
    Ianthe A. E. M. van Belzen, Can Keşmir · 2018 · Immunogenetics
  55. The Role of the Immune Infiltrate in Distinct Cancer Types and Its Clinical Implications
    Jérôme Galon, Daniela Bruni · 2020 · Cancer treatment and research
  56. Differential gene expression of tumor-infiltrating CD4 + T cells in advanced versus early stage colorectal cancer and identification of a gene signature of poor prognosis
    Varun Sasidharan Nair, Reem Saleh, Rowaida Ziad Taha, Salman M. Toor, Khaled Murshed, Ayman Ahmed, Mohamed A. Kurer, Mohamed Abu Nada, Fares Al‐Ejeh, Eyad Elkord · 2020 · OncoImmunology
  57. Cryopreservation of Whole Tumor Biopsies from Rectal Cancer Patients Enable Phenotypic and In Vitro Functional Evaluation of Tumor-Infiltrating T Cells
    Frank Liang, Azar Rezapour, Peter Falk, Eva Angenete, Ulf Yrlid · 2021 · Cancers
  58. The soldiers needed to be awakened: Tumor-infiltrating immune cells
    Wang Yaping, Zhe Wang, Chu Zhuling, Ruolei Li, Fan Pengyu, Guo Lili, Ji Cheng, Zhang Bo, Liuyin Liu, Hou Guangdong et al. · 2022 · Frontiers in Genetics
  59. “To be or not to Be”: Regulatory T cells in melanoma
    Yousif Saleh Ibrahim, Ali H. Amin, Zanko Hassan Jawhar, Mohammad ALIssan ALGhamdi, Ghaidaa Raheem Lateef Al‐Awsi, Abdullah M. Shbeer, Hasan S. AL-Ghamdi, Gamal A. Gabr, Andrés Alexis Ramírez‐Coronel, Abbas Firras Almulla · 2023 · International Immunopharmacology
  60. Wheat Bran Intake Enhances the Secretion of Bacteria-Binding IgA in a Lumen of the Intestinal Tract by Incrementing Short Chain Fatty Acid Production Through Modulation of Gut Microbiota
    Konosuke Matsuzaki, Katsuki Iwai, Yuko Yoshikawa, Yuko Shimamura, Noriyuki Miyoshi, Shigeru Hiramoto, Kenichi Asada, Ryuuta Fukutomi, Hongru Su, Norio Ohashi · 2020 · Natural Product Communications
  61. Understanding and Targeting Human Cancer Regulatory T Cells to Improve Therapy
    H. Ryan Kolb, Nicholas C. Borcherding, Weizhou Zhang · 2021 · Advances in experimental medicine and biology
  62. Regulatory T Cells, as a Target in Anticancer Immunotherapy
    Tomohiro Enokida, Hiroyoshi Nishikawa · 2017 · Immunotherapy
  63. China special issue on gastrointestinal tumors‐Regulatory‐immunoscore—A novel indicator to guide precision adjuvant chemotherapy in colorectal cancer
    Lin Fang, Yang Yao, Xin Guan, Yuanyu Liao, Bojun Wang, Luying Cui, Shuling Han, Haoyi Zou, Dan Su, Yue Ma et al. · 2023 · International Journal of Cancer
  64. Osteopontin Regulates Treg Cell Stability and Function with Implications for Anti-Tumor Immunity and Autoimmunity
    Aigli G. Vakrakou, Evangelia Kourepini, Ioannis Skordos, Natalia Nieto, Vily Panoutsakopoulou, Nikolaos Paschalidis · 2024 · Cancers
  65. Human blood cell transcriptomics unveils dynamic systemic immune modulation along colorectal cancer progression
    Amaia Martínez-Usatorre, Laura Ciarloni, Paolo Angelino, Victoria Wosika, Alessandra Jordano Conforte, Sara Simões Costa, Eric Durandau, Sylvain Monnier‐Benoit, Héctor F. Satizábal, Jérémie Despraz et al. · 2024 · Journal for ImmunoTherapy of Cancer
  66. The HSP90 Inhibitor Pimitespib Targets Regulatory T Cells in the Tumor Microenvironment
    Ayaka Tsuge, Sho Watanabe, Akihito Kawazoe, Yosuke Togashi, Kota Itahashi, Mari Masuda, Atsuo Sai, Shogo Takei, Hiromi Muraoka, Shuichi Ohkubo et al. · 2024 · Cancer Immunology Research
  67. Elevated tumor NOS2/COX2 promotes immunosuppressive phenotypes associated with poor survival in ER– breast cancer
    Lisa A. Ridnour, Robert Y.S. Cheng, William F. Heinz, Milind M. Pore, Ana L. González, Elise L. Femino, Rebecca L. Moffat, Adelaide L. Wink, Fatima Imtiaz, Leandro L. Coutinho et al. · 2025 · JCI Insight
  68. CAR Treg therapies for neurodegenerative diseases
    Daniel N. Stein, Howard Eliot Gendelman · 2026 · iScience
  69. Regulatory T cells in cancer and inflammation
    Haoyi Yang, Haitao Zhang, Ni Xia, Xiang Cheng · 2026 · Signal Transduction and Targeted Therapy
  70. Recent Advances in Development of NIR-II Fluorescent Agents
    Haotian Du, Hao Wan, Hongjie Dai · 2020 · Springer eBooks
  71. Clinical significance of tumor-infiltrating lymphocytes investigated using routine H&E slides in small cell lung cancer
    Guangrun Zhou, Jifang Zheng, Zhiwei Chen, Dan Hu, Suyu Li, Wu Zhuang, Zhiyong He, Gen Lin, Biao Wu, Wei Zhang et al. · 2022 · Radiation Oncology
  72. Integrative analysis of lysine acetylation-related genes and identification of a novel prognostic model for oral squamous cell carcinoma
    Shi‐Zhou Deng, Xuechen Wu, Jiezhang Tang, Lin Lu Dai, Bo Cheng · 2023 · Frontiers in Molecular Biosciences
  73. Sudocetaxel Zendusortide (TH1902) triggers the cGAS/STING pathway and potentiates anti-PD-L1 immune-mediated tumor cell killing
    Michel Demeule, Jean-Christophe Currie, Cyndia Charfi, Alain Zgheib, Isabelle Cousineau, Véronique Lullier, Richard Béliveau, Christian Marsolais, Borhane Annabi · 2024 · Frontiers in Immunology
  74. CRIF1 deficiency induces FOXP3 LOW inflammatory non-suppressive regulatory T cells, thereby promoting antitumor immunity
    S. Lee, Seung Geun Song, Gwanghun Kim, Sehui Kim, Hyun Jung Yoo, Jaemoon Koh, Ye-Ji Kim, Jingwen Tian, Eunji Cho, Youn Soo Choi et al. · 2024 · Science Advances
  75. PARP11 inhibition inactivates tumor-infiltrating regulatory T cells and improves the efficacy of immunotherapies
    Raghavendra Basavaraja, Hongru Zhang, Ágnes Holczbauer, Zhen Feng Lu, Enrico Radaelli, Charles‐Antoine Assenmacher, Subin S. George, Vamshidhar C. Nallamala, Daniel P. Beiting, Mirella L. Meyer‐Ficca et al. · 2024 · Cell Reports Medicine
  76. Multi-omics analysis reveals the landscape of tumor microenvironments in left-sided and right-sided colon cancer
    Dongfang Liu, Chen Li, Zenghua Deng, Nan Luo, Wenxia Li, Wenzhe Hu, Xiang Li, Zichao Qiu, Jianfei Chen, Jirun Peng · 2024 · Frontiers in Medicine
  77. Score of the preoperative absolute number of lymphocytes, monocytes, and neutrophils as a prognostic indicator for patients with gastric cancer
    Hiroaki Saito, Shota Shimizu, Yusuke Kono, Yuki Murakami, Yuji Shishido, Kozo Miyatani, Tomoyuki Matsunaga, Yoji Fukumoto, Keigo Ashida, Yoshiyuki Fujiwara · 2019 · Surgery Today
  78. Evolving Dynamic Biomarkers for Prediction of Immune Responses to Checkpoint Inhibitors in Cancer
    Afsheen Raza, Maysaloun Merhi, Allan Relecom, Queenie Fernandes, Varghese Philipose Inchakalody, Abdul Rehman Zar Gul, Shahab Uddin M.S., Mohammed Ussama Al Homsi, Said Dermime · 2021 · IntechOpen eBooks
  79. Novel acetylation-related gene signatures for predicting the prognosis of patients with colorectal cancer
    Zhuang Jing, Feng Ziwang, Yinhang Wu, Zhou Yani, Jian Chu, Jingwen Wu, Shuwen Han · 2022 · Human Cell
  80. Transcriptome of Tumor-Infiltrating T Cells in Colorectal Cancer Patients Uncovered a Unique Gene Signature in CD4+ T Cells Associated with Poor Disease-Specific Survival
    Salman M. Toor, Varun Sasidharan Nair, Reem Saleh, Rowaida Ziad Taha, Khaled Murshed, Mahmood Al‐Dhaheri, Mahwish Khawar, Ayman Ahmed, Mohamed A. Kurer, Mohamed Abu Nada et al. · 2021 · Vaccines
  81. A pyroptosis-related lncRNA risk model for the prediction of prognosis and immunotherapy response in head and neck squamous cell carcinoma
    Jingyuan Ren, Bingrui Yan, Xurui Wang, Yifei Wang, Qiuying Li, Yanan Sun · 2024 · Frontiers in Oncology
  82. Patients‐Derived Organoids Sequencing‐based FOXP4 Facilitates Radioresistance by Transcriptionally Modifying GPX4 to Regulate ferroptosis in Colorectal Cancer
    Qianping Chen, Yuzhao Jin, Luyu Liao, Rong Shen, Xingnan Ge, Qingyu Jiang, Ying Huang, Quanquan Sun, Dong Liu, Luying Liu et al. · 2025 · Advanced Science
  83. PD-1 antibody-bound progenitor-exhausted CD8+ T cells in lymph nodes boost PD-1-blockade anti-tumor immunity in gastrointestinal cancer
    Yohei Nose, Yoshiaki Yasumizu, Takuro Saito, Yamami Nakamura, Koichi Jinushi, Kaoru Fujikawa, K. Momose, K. Yamashita, Koji Tanaka, Kazuyoshi Yamamoto et al. · 2026 · Nature Communications
  84. Prognostic value of LINC02560 in colorectal cancer correlates with tumor microenvironment immunity
    Chunying Luo, Fahui Liu, Wei-Chao Su, Puze Long, Jiadong Liang, Wanyun Hou, Haifeng Jiang, Xi‐Dai Long, Guoqiang Su · 2021 · Journal of Cancer
  85. Pathological complete response to neoadjuvant chemotherapy may improve antitumor immune response via reduction of regulatory T cells in muscle-invasive bladder cancer
    Daiki Ikarashi, Shigehisa Kitano, Takashi Tsuyukubo, Makiko Yamashita, Tomohiko Matsuura, Shigekatsu Maekawa, Renpei Kato, Yoichiro Kato, Mitsugu Kanehira, Ryo Takata et al. · 2024 · Scientific Reports
  86. Myeloid derived suppressor cells in peripheral blood can be a prognostic factor in canine transitional cell carcinoma
    Shohei Yokota, Tomohiro Yonezawa, Yasuyuki Momoi, Shingo Maeda · 2024 · Veterinary Immunology and Immunopathology
  87. Preclinical efficacy of carfilzomib in BRAF ‐mutant colorectal cancer models
    Federica Maione, Daniele Oddo, Federica Galvagno, Chiara Falcomatà, Marta Pandini, Marco Macagno, Valeria Pessei, Ludovic Barault, Chiara Gigliotti, Alessia Mira et al. · 2024 · Molecular Oncology
  88. What is the relevance of FoxP3 in the tumor microenvironment and cancer outcomes?
    Abdo Meyiah, Eyad Elkord · 2024 · Expert Review of Clinical Immunology
  89. Predictive nomogram of the clinical outcomes of colorectal cancer based on methylated SEPT9 and intratumoral IL-10+ Tregs infiltration
    Jie Sun, Songli Shi, Chao Sun, Jiangping Wang, Xiaohui Yang, Zhengduo Yang, Jing Xu, Shiwu Zhang · 2024 · Journal of Translational Medicine
  90. Immune-Modulating Effects of Conventional Therapies in Colorectal Cancer
    Erta Kalanxhi, Sebastian Meltzer, Anne Hansen Ree · 2020 · Cancers
  91. Genetic Variants in the Regulatory T cell–Related Pathway and Colorectal Cancer Prognosis
    Sonja Neumeyer, Xinwei Hua, Petra Seibold, Lina Jansen, Axel Benner, Barbara Burwinkel, Niels Halama, Sonja I. Berndt, Amanda I. Phipps, Lori C. Sakoda et al. · 2020 · Cancer Epidemiology Biomarkers & Prevention
  92. A Novel Pyroptosis-Related Gene Signature for Early-Stage Lung Squamous Cell Carcinoma
    Xiaoyan Li, Jie He · 2021 · International Journal of General Medicine
  93. SH2D4A downregulation due to loss of chromosome 8p is associated with poor prognosis and low T cell infiltration in colorectal cancer
    Takuro Matsumoto, Hirokazu Okayama, Shotaro Nakajima, Katsuharu Saito, Misato Ito, Akinao Kaneta, Yasuyuki Kanke, Hisashi Onozawa, Suguru Hayase, Shotaro Fujita et al. · 2021 · British Journal of Cancer
  94. Prognostic value of FOXP3 + regulatory T cells in patients with diffuse large B-cell lymphoma: a systematic review and meta-analysis
    Yuping Bai, Tingting He, Liyan Zhang, Qianqian Liu, Jing Bo Yang, Ziru Zhao, Kehu Yang, Min Zhang · 2022 · BMJ Open
  95. Correlations between Circulating and Tumor-Infiltrating CD4+ Treg Subsets with Immune Checkpoints in Colorectal Cancer Patients with Early and Advanced Stages
    Mohammad A. Al-Mterin, Khaled Murshed, Eyad Elkord · 2022 · Vaccines
  96. Number of FoxP3+ regulatory T-cells are associated with recurrence in vulvar squamous cell carcinoma
    Deniz Arık, Tutku Benli, Elçin Telli · 2022 · Journal of Gynecologic Oncology
  97. Development and experimental verification of a prognosis model for disulfidptosis-associated genes in HNSCC
    Yushen Li, Lu Tao, Jiajun Xin, Yifei Dai, Xiantao Chen, Jiatong Zou, Rui Wang, Bowei Wang, Zhihui Liu · 2024 · Medicine
  98. Immunoregulation: the interplay between metabolism and redox homeostasis
    Elena Perpiñán, Alberto Sanchez Fueyo, Niloufar Safinia · 2023 · Frontiers in Transplantation
  99. TIGIT Blockade Reshapes the Tumor Microenvironment Based on the Single-cell RNA-Sequencing Analysis
    Yanyan Lang, Hao Huang, Hongwei� Jiang, Shaoxian Wu, Yaping Chen, Bin Xu, Yingting Liu, Dawei Zhu, Xiao Wei Zheng, Lujun Chen et al. · 2024 · Journal of Immunotherapy
  100. Pathomic and bioinformatics analysis of clinical-pathological and genomic factors for pancreatic cancer prognosis
    Yang Li, Lujuan Pan, Joseph Mugaanyi, Hua Li, Gehui Li, Jing Huang, Lei Dai · 2024 · Scientific Reports