Local clearance of senescent cells attenuates the development of post-traumatic osteoarthritis and creates a pro-regenerative environment
Jeon, Ok Hee, Kim, Chaekyu, Laberge, Remi-Martin, Demaria, Marco, Rathod, Sona, Vasserot, Alain P, Chung, Jae Wook, Kim, Do Hun +6 more·2017·Nature Medicine
DOI 10.1038/nm.4324
Cited by (1,499)
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- Additional file 1 of Toll-like receptor 2 induced senescence in intervertebral disc cells of patients with back pain can be attenuated by o-vanillinMatthew Mannarino, Hosni Cherif, Li Li, Kai Sheng, Oded Rabau, Jarzem, Peter, Weber, Michael H., Jean Albert Ouellet, Lisbet Haglund · 2021 · Figshare
- Additional file 1 of Targeting an inflammation-amplifying cell population can attenuate osteoarthritis-associated painAkshay Pandey, Mamta Singla, Geller, Ana, Stuart Barry Goodman, Nidhi Bhutani · 2024 · Figshare
- Additional file 2 of Eliminating senescent chondrogenic progenitor cells enhances chondrogenesis under intermittent hydrostatic pressure for the treatment of OAHanhao Dai, Chen, Ran, Gui, Chang, Tao, Tianqi, Ge, Yingbin, Xilian Zhao, Qin, Ran, Yao, Wangxiang, Gu, Song, Jiang, Yiqiu et al. · 2020 · Figshare
- Additional file 2 of TGF-β1 regulates chondrocyte proliferation and extracellular matrix synthesis via circPhf21a-Vegfa axis in osteoarthritisShiyuan Lin, Huizi Li, Wu, Biao, Jie Shang, Jiang, Ning, Rong Peng, Baizhou Xing, Xu, Xianghe, Lu, Huading · 2022 · Figshare
- Additional file 2 of Receptor tyrosine kinase C-kit promotes a destructive phenotype of FLS in osteoarthritis via intracellular EMT signalingCao, Xu, Wu, Song, Wang, Xinxing · 2023 · Figshare
- Additional file 2 of LncRNA AC006064.4–201 serves as a novel molecular marker in alleviating cartilage senescence and protecting against osteoarthritis by destabilizing CDKN1B mRNA via interacting with PTBP1Panyang Shen, Gao, Jun, Huang, Shaohan, Chenan You, Wang, Haitao, Pengyu Chen, Teng Yao, Gao, Tianyou, Bohao Zhou, Shen, Shuying et al. · 2023 · Figshare
- Additional file 1 of Comorbidity phenotypes and risk of mortality in patients with osteoarthritis in the UK: a latent class analysisDawit Tefra Zemedikun, Helena Lee, Krishnarajah Nirantharakumar, Karim Raza, Joht Singh Chandan, Janet M. Lord, Thomas Jackson · 2022 · Figshare
- Additional file 2 of Targeting an inflammation-amplifying cell population can attenuate osteoarthritis-associated painAkshay Pandey, Mamta Singla, Geller, Ana, Stuart Barry Goodman, Nidhi Bhutani · 2024 · Figshare
- Additional file 1 of LncRNA AC006064.4–201 serves as a novel molecular marker in alleviating cartilage senescence and protecting against osteoarthritis by destabilizing CDKN1B mRNA via interacting with PTBP1Panyang Shen, Gao, Jun, Huang, Shaohan, Chenan You, Wang, Haitao, Chen, Pengyu, Teng Yao, Gao, Tianyou, Bohao Zhou, Shen, Shuying et al. · 2023 · Figshare
- Additional file 2 of Mechanical overloading-induced miR-325-3p reduction promoted chondrocyte senescence and exacerbated facet joint degenerationZhao, Jinyun, Li, Chengjun, Qin, Tian et al. · 2023 · Figshare
- Additional file 1 of Receptor tyrosine kinase C-kit promotes a destructive phenotype of FLS in osteoarthritis via intracellular EMT signalingCao, Xu, Wu, Song, Wang, Xinxing · 2023 · Figshare
- Additional file 3 of Eliminating senescent chondrogenic progenitor cells enhances chondrogenesis under intermittent hydrostatic pressure for the treatment of OAHanhao Dai, Chen, Ran, Gui, Chang, Tao, Tianqi, Ge, Yingbin, Xilian Zhao, Qin, Ran, Yao, Wangxiang, Gu, Song, Jiang, Yiqiu et al. · 2020 · Figshare
- Additional file 7 of Eliminating senescent chondrogenic progenitor cells enhances chondrogenesis under intermittent hydrostatic pressure for the treatment of OAHanhao Dai, Chen, Ran, Gui, Chang, Tao, Tianqi, Ge, Yingbin, Xilian Zhao, Qin, Ran, Yao, Wangxiang, Gu, Song, Jiang, Yiqiu et al. · 2020 · Figshare
- Additional file 5 of Receptor tyrosine kinase C-kit promotes a destructive phenotype of FLS in osteoarthritis via intracellular EMT signalingCao, Xu, Wu, Song, Wang, Xinxing · 2023 · Figshare
- Additional file 4 of Receptor tyrosine kinase C-kit promotes a destructive phenotype of FLS in osteoarthritis via intracellular EMT signalingCao, Xu, Wu, Song, Wang, Xinxing · 2023 · Figshare
- Additional file 6 of Senescence-accelerated mice prone 8 (SAMP8) in male as a spontaneous osteoarthritis modelSanada, Yohei, Yasunari Ikuta, Chenyang Ding, Masahiro Shinohara, Dilimulati Yimiti, Ishitobi, Hiroyuki, Keita Nagira, Lee, Minjung, Akimoto, Takayuki, Shibata, Sachi et al. · 2022 · Figshare
- Additional file 2 of Toll-like receptor 2 induced senescence in intervertebral disc cells of patients with back pain can be attenuated by o-vanillinMatthew Mannarino, Hosni Cherif, Li Li, Kai Sheng, Oded Rabau, Jarzem, Peter, Weber, Michael H., Jean Albert Ouellet, Lisbet Haglund · 2021 · Figshare
- Additional file 6 of Receptor tyrosine kinase C-kit promotes a destructive phenotype of FLS in osteoarthritis via intracellular EMT signalingCao, Xu, Wu, Song, Wang, Xinxing · 2023 · Figshare