Local clearance of senescent cells attenuates the development of post-traumatic osteoarthritis and creates a pro-regenerative environment

Jeon, Ok Hee, Kim, Chaekyu, Laberge, Remi-Martin, Demaria, Marco, Rathod, Sona, Vasserot, Alain P, Chung, Jae Wook, Kim, Do Hun +6 more·2017·Nature Medicine

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  81. Additional file 1 of MiR-653-5p drives osteoarthritis pathogenesis by modulating chondrocyte senescence
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  82. Additional file 1 of Clearance of senescent cells with ABT-263 improves biological functions of synovial mesenchymal stem cells from osteoarthritis patients
    Miura, Yugo, Endo, Kentaro, Komori, Keiichiro · 2022 · Figshare
  83. Additional file 1 of Toll-like receptor 2 induced senescence in intervertebral disc cells of patients with back pain can be attenuated by o-vanillin
    Matthew Mannarino, Hosni Cherif, Li Li, Kai Sheng, Oded Rabau, Jarzem, Peter, Weber, Michael H., Jean Albert Ouellet, Lisbet Haglund · 2021 · Figshare
  84. Additional file 1 of Targeting an inflammation-amplifying cell population can attenuate osteoarthritis-associated pain
    Akshay Pandey, Mamta Singla, Geller, Ana, Stuart Barry Goodman, Nidhi Bhutani · 2024 · Figshare
  85. Additional file 2 of Eliminating senescent chondrogenic progenitor cells enhances chondrogenesis under intermittent hydrostatic pressure for the treatment of OA
    Hanhao Dai, Chen, Ran, Gui, Chang, Tao, Tianqi, Ge, Yingbin, Xilian Zhao, Qin, Ran, Yao, Wangxiang, Gu, Song, Jiang, Yiqiu et al. · 2020 · Figshare
  86. Additional file 2 of TGF-β1 regulates chondrocyte proliferation and extracellular matrix synthesis via circPhf21a-Vegfa axis in osteoarthritis
    Shiyuan Lin, Huizi Li, Wu, Biao, Jie Shang, Jiang, Ning, Rong Peng, Baizhou Xing, Xu, Xianghe, Lu, Huading · 2022 · Figshare
  87. Additional file 2 of Receptor tyrosine kinase C-kit promotes a destructive phenotype of FLS in osteoarthritis via intracellular EMT signaling
    Cao, Xu, Wu, Song, Wang, Xinxing · 2023 · Figshare
  88. Additional file 2 of LncRNA AC006064.4–201 serves as a novel molecular marker in alleviating cartilage senescence and protecting against osteoarthritis by destabilizing CDKN1B mRNA via interacting with PTBP1
    Panyang Shen, Gao, Jun, Huang, Shaohan, Chenan You, Wang, Haitao, Pengyu Chen, Teng Yao, Gao, Tianyou, Bohao Zhou, Shen, Shuying et al. · 2023 · Figshare
  89. Additional file 1 of Comorbidity phenotypes and risk of mortality in patients with osteoarthritis in the UK: a latent class analysis
    Dawit Tefra Zemedikun, Helena Lee, Krishnarajah Nirantharakumar, Karim Raza, Joht Singh Chandan, Janet M. Lord, Thomas Jackson · 2022 · Figshare
  90. Additional file 2 of Targeting an inflammation-amplifying cell population can attenuate osteoarthritis-associated pain
    Akshay Pandey, Mamta Singla, Geller, Ana, Stuart Barry Goodman, Nidhi Bhutani · 2024 · Figshare
  91. Additional file 1 of LncRNA AC006064.4–201 serves as a novel molecular marker in alleviating cartilage senescence and protecting against osteoarthritis by destabilizing CDKN1B mRNA via interacting with PTBP1
    Panyang Shen, Gao, Jun, Huang, Shaohan, Chenan You, Wang, Haitao, Chen, Pengyu, Teng Yao, Gao, Tianyou, Bohao Zhou, Shen, Shuying et al. · 2023 · Figshare
  92. Additional file 2 of Mechanical overloading-induced miR-325-3p reduction promoted chondrocyte senescence and exacerbated facet joint degeneration
    Zhao, Jinyun, Li, Chengjun, Qin, Tian et al. · 2023 · Figshare
  93. Additional file 1 of Receptor tyrosine kinase C-kit promotes a destructive phenotype of FLS in osteoarthritis via intracellular EMT signaling
    Cao, Xu, Wu, Song, Wang, Xinxing · 2023 · Figshare
  94. Additional file 3 of Eliminating senescent chondrogenic progenitor cells enhances chondrogenesis under intermittent hydrostatic pressure for the treatment of OA
    Hanhao Dai, Chen, Ran, Gui, Chang, Tao, Tianqi, Ge, Yingbin, Xilian Zhao, Qin, Ran, Yao, Wangxiang, Gu, Song, Jiang, Yiqiu et al. · 2020 · Figshare
  95. Additional file 7 of Eliminating senescent chondrogenic progenitor cells enhances chondrogenesis under intermittent hydrostatic pressure for the treatment of OA
    Hanhao Dai, Chen, Ran, Gui, Chang, Tao, Tianqi, Ge, Yingbin, Xilian Zhao, Qin, Ran, Yao, Wangxiang, Gu, Song, Jiang, Yiqiu et al. · 2020 · Figshare
  96. Additional file 5 of Receptor tyrosine kinase C-kit promotes a destructive phenotype of FLS in osteoarthritis via intracellular EMT signaling
    Cao, Xu, Wu, Song, Wang, Xinxing · 2023 · Figshare
  97. Additional file 4 of Receptor tyrosine kinase C-kit promotes a destructive phenotype of FLS in osteoarthritis via intracellular EMT signaling
    Cao, Xu, Wu, Song, Wang, Xinxing · 2023 · Figshare
  98. Additional file 6 of Senescence-accelerated mice prone 8 (SAMP8) in male as a spontaneous osteoarthritis model
    Sanada, Yohei, Yasunari Ikuta, Chenyang Ding, Masahiro Shinohara, Dilimulati Yimiti, Ishitobi, Hiroyuki, Keita Nagira, Lee, Minjung, Akimoto, Takayuki, Shibata, Sachi et al. · 2022 · Figshare
  99. Additional file 2 of Toll-like receptor 2 induced senescence in intervertebral disc cells of patients with back pain can be attenuated by o-vanillin
    Matthew Mannarino, Hosni Cherif, Li Li, Kai Sheng, Oded Rabau, Jarzem, Peter, Weber, Michael H., Jean Albert Ouellet, Lisbet Haglund · 2021 · Figshare
  100. Additional file 6 of Receptor tyrosine kinase C-kit promotes a destructive phenotype of FLS in osteoarthritis via intracellular EMT signaling
    Cao, Xu, Wu, Song, Wang, Xinxing · 2023 · Figshare