Validating Stat3 in cancer therapy

Darnell, James E·2005·Nature Medicine

Cited by (316)

Items 201–300 of 316

  1. STAT3 inhibition in prostate and pancreatic cancer lines by STAT3 binding sequence oligonucleotides: differential activity between 5′ and 3′ ends
    Lewis, H. Dan, Winter, Ashley, Murphy, Thomas F., Tripathi, Snehlata, Pandey, Virendra N., Barton, Beverly E. · 2008 · Molecular Cancer Therapeutics
  2. STAT3 inhibitor, cucurbitacin I, is a novel therapeutic agent for osteosarcoma
    Toru Oi, Kunihiro Asanuma, Akihiko Matsumine, Takao Matsubara, Tomoki Nakamura, Takahiro Iino, Yumiko Asanuma, Mikinobu Goto, Kazuma Okuno, Takuya Kakimoto et al. · 2016 · International Journal of Oncology
  3. Transcription Factor STAT3 As a Prognostic Marker and Therapeutic Target in Cancer
    David A. Frank · 2013 · Journal of Clinical Oncology
  4. Clinical Significance of G Protein-Coupled Receptor 110 (GPR110) as a Novel Prognostic Biomarker in Osteosarcoma
    Zhiqiang Liu, Guorong Zhang, Changlei Zhao, Juming Li · 2018 · Medical Science Monitor
  5. Novel potent azetidine-based compounds irreversibly inhibit Stat3 activation and induce antitumor response against human breast tumor growth in vivo
    Peibin Yue, Yinsong Zhu, Christine Brotherton‐Pleiss, Wen‐Zhen Fu, Nagendra Verma, Jasmine Chen, Kayo Nakamura, Weiliang Chen, Yue Chen, Felix Alonso-Valenteen et al. · 2022 · Cancer Letters
  6. A novel oncolytic adenovirus selectively silences the expression of tumor-associated STAT3 and exhibits potent antitumoral activity
    Zhiqiang Han, Zhenya Hong, Caihong Chen, Qinglei Gao, Danfeng Luo, Yong Fang, Yang Cao, Tao Zhu, Xuefeng Jiang, Quanfu Ma et al. · 2009 · Carcinogenesis
  7. 3D culture reveals a signaling network
    Senthil K. Muthuswamy · 2011 · Breast Cancer Research
  8. Novel STAT3 small-molecule inhibitors identified by structure-based virtual ligand screening incorporating SH2 domain flexibility
    Ren Kong, Uddalak Bharadwaj, Thomas Kris Eckols, Mikhail I. Kolosov, Haoyi Wu, Francisco J. Santa Cruz-Pavlovich, Alison Shaw, Oluwatomilona I. Ifelayo, Hong Zhao, Moses M. Kasembeli et al. · 2021 · Pharmacological Research
  9. Development of new N-arylbenzamides as STAT3 dimerization inhibitors
    Murali K. Urlam, Roberta Pireddu, Yiyu Ge, Xiaolei Zhang, Ying Sun, Harshani R. Lawrence, Wayne C. Guida, Saı̈d M. Sebti, Nicholas J. Lawrence · 2013 · MedChemComm
  10. Curcumin Combined with Thalidomide Reduces Expression of STAT3 and Bcl-xL, Leading to Apoptosis in Acute Myeloid Leukemia Cell Lines
    Mahnaz Mohammadi Kian, Mahdieh Salemi, Mohammad Bahadoran, Atousa Haghi, Nasrin Dashti, Saeed Mohammadi, Shahrbano Rostami, Bahram Chahardouli, Davood Babakhani, Mohsen Nikbakht · 2020 · Drug Design Development and Therapy
  11. Ginsenoside Rg1 Inhibits Microglia Pyroptosis Induced by Lipopolysaccharide Through Regulating STAT3 Signaling
    Yueyi Yao, Chang‐Yan Li, Fusheng Qian, Yu Zhao, Xiaoyi Shi, Dan Hong, Qinglong Ai, Lianmei Zhong · 2021 · Journal of Inflammation Research · Retracted
  12. Nanoparticle-mediated metronomic chemotherapy in cancer: A paradigm of precision and persistence
    Apoorv Kirti, Faizan Zarreen Simnani, Snehasmita Jena, Sudakshya S. Lenka, Chethana Kalalpitiya, Shaikh Sheeran Naser, Dibyangshee Singh, Anmol Choudhury, Rudra Narayan Sahu, Anu Yadav et al. · 2024 · Cancer Letters
  13. The JAK/STAT pathway regulates proximo‐distal patterning in Drosophila
    Aidee Ayala‐Camargo, Laura A. Ekas, Maria Sol Flaherty, Gyeong‐Hun Baeg, Erika A Bach · 2007 · Developmental Dynamics
  14. IL-6, IL-10, c-Jun and STAT3 expression in B-CLL
    Halina Antosz, Katarzyna Wojciechowska, Joanna Sajewicz, Dorota Choroszyńska, Barbara Marzec‐Kotarska, Magdalena Osiak, Natalia Pająk, Waldemar Tomczak, Małgorzata Jargiełło-Baszak, Jacek Baszak · 2014 · Blood Cells Molecules and Diseases
  15. Carbazole Derivatives as STAT Inhibitors: An Overview
    Anna Caruso, Alexia Barbarossa, Alessia Carocci, Giovanni Salzano, Maria Stefania Sinicropi, Carmela Saturnino · 2021 · Applied Sciences
  16. Selective Inhibition of STAT3 with Respect to STAT1: Insights from Molecular Dynamics and Ensemble Docking Simulations
    Semen O. Yesylevskyy, Christophe Ramseyer, Marc Pudlo, Jean‐René Pallandre, Christophe Borg · 2016 · Journal of Chemical Information and Modeling
  17. Novel quinazoline-based sulfonamide derivative (3D) induces apoptosis in colorectal cancer by inhibiting JAK2–STAT3 pathway
    Omar Abdullah Al-Obeed, Mansoor‐Ali Vaali‐Mohammed, Wagdy Mohamed Eldehna, Khayal Al‐Khayal, Amer Mahmood, Hatem A. Abdel‐Aziz, Ahmed Zubaidi, Ahmed Mahmoud Alafeefy, Maha‐Hamadien Abdulla, Rehan Ahmad · 2018 · OncoTargets and Therapy
  18. Pharmacokinetic evaluation, molecular docking and in vitro biological evaluation of 1, 3, 4-oxadiazole derivatives as potent antioxidants and STAT3 inhibitors
    Rashmin Khanam, Iram Iqbal Hejazi, Syed Shahabuddin, Abdul Roouf Bhat, Fareeda Athar · 2018 · Journal of Pharmaceutical Analysis
  19. Signaling Pathways Involved in 5-FU Drug Resistance in Cancer
    Fahima Danesh Pouya, Yousef Rasmi, Mohadeseh Nemati · 2022 · Cancer Investigation
  20. Sarcophine-Diol, a Skin Cancer Chemopreventive Agent, Inhibits Proliferation and Stimulates Apoptosis in Mouse Melanoma B16F10 Cell Line
    Pawel T. Szymanski, Bhimanna Kuppast, Safwat A. Ahmed, Sherief Ibrahim Khalifa, Hesham T. Y. Fahmy · 2011 · Marine Drugs
  21. Linker Variation and Structure–Activity Relationship Analyses of Carboxylic Acid-based Small Molecule STAT3 Inhibitors
    Francisco Lopez‐Tapia, Christine Brotherton‐Pleiss, Peibin Yue, Heide A. Murakami, Ana Carolina Costa Araujo, Bruna Reis dos Santos, Erin Ichinotsubo, Anna Rabkin, Raj Shah, Megan J. Lantz et al. · 2018 · ACS Medicinal Chemistry Letters
  22. Prevention of trauma/hemorrhagic shock-induced lung apoptosis by IL-6-mediated activation of Stat3
    Moran, Ana, Tsimelzon, Anna I., Mastrangelo, Mary‐Ann A., Wu, Yong, Yu, Bi, Hilsenbeck, Susan G., Poli, Valeria, Tweardy, David J. · 2009 · Clinical and Translational Science
  23. Novel polyurethane-based ionene nanoparticles electrostatically stabilized with hyaluronic acid for effective gene therapy
    Athar Mahdieh, Hamidreza Motasadizadeh, Samane Maghsoudian, Alireza Sabzevari, Fereshte Khalili, Hamid Yeganeh, Bo Nyström · 2024 · Colloids and Surfaces B Biointerfaces
  24. A novel indole ethyl isothiocyanate (7Me-IEITC) with anti-proliferative and pro-apoptotic effects on platinum-resistant human ovarian cancer cells
    Rakesh K. Singh, Thilo S. Lange, Kyukwang Kim, Sunil K. Shaw, Laurent Brard · 2008 · Gynecologic Oncology
  25. Vasoactive intestinal peptide protects alveolar epithelial cells against hyperoxia via promoting the activation of STAT3
    Xiaoxiao Ao, Fang Fang, Feng Xu · 2011 · Regulatory Peptides
  26. Functional antibody delivery: Advances in cellular manipulation
    Kayla C. Koch, Gregory N. Tew · 2022 · Advanced Drug Delivery Reviews
  27. NSC114792, a novel small molecule identified through structure-based computational database screening, selectively inhibits JAK3
    Byung‐Hak Kim, Jun‐Goo Jee, Changhong Yin, Claudio Sandoval, Somasundaram Jayabose, Daisuke Kitamura, Erika A Bach, Gyeong‐Hun Baeg · 2010 · Molecular Cancer
  28. Low expression of AIM2 combined with high expression of p‑STAT3 is associated with poor prognosis in hypopharyngeal squamous cell carcinoma
    Zhen Li, Xinli Shi, Hui Li, Weiyi Wang, Xiaoming Li · 2019 · Oncology Reports
  29. The Jak-STAT Signal Transduction Pathway in Melanoma
    Courtney Nicholas, Gregory B. · 2011 · InTech eBooks
  30. STAT3 Inhibits Apoptosis of Human Renal Tubular Epithelial Cells Induced by ATP Depletion/Recovery
    Jianzhong Wang, Chun Ouyang, Xiangmei Chen, Bo Fu, Yang Lü, Quan Hong · 2007 · Nephron Experimental Nephrology
  31. Identification of common key genes and pathways between Covid-19 and lung cancer by using protein-protein interaction network analysis
    Kang Soon Nan, Kalimuthu Karuppanan, Suresh Kumar · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  32. Expression of STATs and their inhibitors SOCS and PIAS in brain tumors. In vitro and in vivo study.
    Jiří Ehrmann, Nicol Straková, Katerina Vrzalikova, R Hezova, Z Kolar · 2008 · PubMed
  33. Dual-inhibitors of STAT5 and STAT3: studies from molecular docking and molecular dynamics simulations
    Shengjuan Shao, Rilei Yu, Yanqing Yu, Yanni Li · 2014 · Journal of Molecular Modeling
  34. Molecular mechanism of gossypol mediating CCL2 and IL‑8 attenuation in triple‑negative breast cancer cells
    Samia S. Messeha, Najla O. Zarmouh, Patricia Mendonca, Carolyn Cotton, Karam F. A. Soliman · 2020 · Molecular Medicine Reports
  35. TIMP1 induces CD44 expression and the activation and nuclear translocation of SHP1 during the late centrocyte/post-germinal center B cell differentiation
    Young-Sik Kim, Dong Wan Seo, Su-Kang Kong, Jeong Hyeon Lee, Eung-Seok Lee, Maryalice Stetler‐Stevenson, William George Stetler‐Stevenson · 2008 · Cancer Letters
  36. Stattic enhances the anti-proliferative effect of docetaxel via the Bax/Bcl-2/cyclin B axis in human cancer cells
    Jamal Mohammadian, Ommoleila Molavi, Mohammad Bagher Pirouzpanah, Ali Akbar Rahim Rahimi, Nasser Samadi · 2018 · Process Biochemistry
  37. YB-1 suppression induces STAT3 proteolysis and sensitizes renal cancer to interferon-α
    Ario Takeuchi, Masaki Shiota, Katsunori Tatsugami, Akira Yokomizo, Kentaro Kuroiwa, Takashi Dejima, Shingo Tanaka, Momoe Itsumi, Masatoshi Eto, Seiji Naito · 2012 · Cancer Immunology Immunotherapy
  38. Inhibitory Mechanism of the Outer Membrane Growth of Chronic Subdural Hematomas
    Koji Osuka, Yasuo Watanabe, Nobuteru Usuda, Masahiro Aoyama, Kenichiro Iwami, Mikinobu Takeuchi, Takeya Watabe, Masakazu Takayasu · 2016 · Journal of Neurotrauma
  39. A novel small-molecule inhibitor of hepatitis C virus replication acts by suppressing signal transducer and activator of transcription 3
    Yuqiang Niu, Youhui Si, Yan Li, Xiaojing Chi, Xiang Olivia Li, Xiuying Liu, Li Duan, Min Cheng, Jingjing Fan, Shuyi Si et al. · 2015 · Journal of Antimicrobial Chemotherapy
  40. Interferon-alpha treatment may negatively influence disease progression in melanoma patients by hyperactivation of STAT3 protein
    L. Humpoliková-Adámková, Jan Kovařík, Ladislav Dušek, L Lauerová, V. Boudný, V. Fait, Miloslava Fojtová, Eva Krejčí, Aleš Kovařı́k · 2009 · European Journal of Cancer
  41. Ureido‐Pyridazinone Derivatives: Insights into the Structural and Conformational Properties for STAT3 Inhibition
    Fiorella Meneghetti, Stefania Villa, D. Masciocchi, Daniela Barlocco, Lucio Toma, Dong‐Cho Han, Byoung‐Mog Kwon, Naohisa Ogo, Akira Asai, Laura Legnani et al. · 2015 · European Journal of Organic Chemistry
  42. Biochemical Properties of a Decoy Oligodeoxynucleotide Inhibitor of STAT3 Transcription Factor
    David S. Lee, Rachel A. O’Keefe, Patrick K. Ha, Jennifer Rubin Grandis, Daniel E. Johnson · 2018 · International Journal of Molecular Sciences
  43. Exploration of novel isoxazole-fused quinone derivatives as anti-colorectal cancer agents through inhibiting STAT3 and elevating ROS level
    Lidan Zhang, Pingxian Liu, Yunhan Jiang, Dongmei Fan, Xinlian He, Jiangnan Zhang, Baozhu Luo, Jing Sui, Youfu Luo, Xin-Yuan Fu et al. · 2024 · European Journal of Medicinal Chemistry
  44. STAT3 Inhibition Induces Apoptosis in Cancer Cells Independent of STAT1 or STAT2.
    Adetola Shodeinde, Kalyani Ginjupalli, H Dan Lewis, Sheraz Riaz, Beverly E. Barton · 2013 · PubMed
  45. The antihypertension drug doxazosin suppresses JAK/STATs phosphorylation and enhances the effects of IFN-α/γ-induced apoptosis
    Mi Sun Park, Boh-Ram Kim, Sokbom Kang, Dae-Yong Kim, Seung Bae Rho · 2014 · Genes & Cancer
  46. Design, synthesis, biological evaluation and molecular docking of novel metronidazole derivatives as selective and potent JAK3 inhibitors
    Ya-Li Sang, Yongtao Duan, Han‐Yue Qiu, Pengfei Wang, Jigar A. Makawana, Zhong‐Chang Wang, Hai‐Liang Zhu, Zhenxiang He · 2014 · RSC Advances
  47. Anti-tumour effect of tocilizumab for osteosarcoma cell lines
    Tomohito Hagi, Tomoki Nakamura, Kouji Kita, Takahiro Iino, Kunihiro Asanuma, Akihiro Sudo · 2020 · Bone and Joint Research
  48. STAT3 Decoy Oligodeoxynucleotides Suppress Liver Inflammation and Fibrosis in Liver Cancer Cells and a DDC-Induced Liver Injury Mouse Model
    Hye Jin Choi, Young-Ah Kim, Junghwa Ryu, Kwan‐Kyu Park, Sun-Jae Lee, Byung Seok Kim, Jeong-En Song, Joo Dong Kim · 2024 · Molecules
  49. Increasing Antitumor Activity of JAK Inhibitor by Simultaneous Blocking Multiple Survival Signaling Pathways in Human Ovarian Cancer
    Wei Xiong Wen, Ernest Soyoung Han, Thanh Hue Dellinger, Jun Wu, Yuming Guo, Ralf Buettner, David A. Horne, Richard Jove, John Hosei Yim · 2019 · Translational Oncology
  50. A frequent somatic mutation in the 3'UTR of GAPDH facilitates the development of ovarian cancer by creating a miR‑125b binding site
    Peisen Liu, Yu-Min Zhong, Ting Cao, Xiujie Sheng, Huang Huang · 2020 · Oncology Reports
  51. SIPAR negatively regulates STAT3 signaling and inhibits progression of melanoma
    Fangli Ren, Fuqin Su, Hongxiu Ning, Yangmeng Wang, Yongtao Geng, Yarui Feng, Yinyin Wang, Yanquan Zhang, Zhe Hu Jin, Yi Li et al. · 2013 · Cellular Signalling
  52. Comparative screening and validation as a novel tool to identify STAT-specific inhibitors
    Małgorzata Szeląg, Anna Czerwoniec, Joanna Wesoły, Hans A.R. Bluyssen · 2014 · European Journal of Pharmacology
  53. Development of a sensitive and specific liquid chromatography/mass spectrometry method for the quantification of cucurbitacin I (JSI-124) in rat plasma.
    Ommoleila Molavi, Anooshirvan Shayeganpour, Vishwa Somayaji, Samar Ismail Hamdy, Dion R Brocks, Afsaneh Lavasanifar, Glen S. Kwon, John Samuel · 2006 · PubMed
  54. Targeting signal-transducer-and-activator-of-transcription 3 sensitizes human cutaneous melanoma cells to BRAF inhibitor
    Xiaohui Wang, Huajun Qu, Yinghe Dong, Guozhi Wang, Yuchen Zhen, Linxia Zhang · 2018 · Cancer Biomarkers
  55. STAT3 promotes chronic lymphocytic leukemia progression through upregulating SMYD3 expression
    Wei Ma, Yingying Zhang, Yu Meng Qi, Shi-Dong Guo · 2018 · Archives of Medical Science
  56. Targeting the Tumor Microenvironment by Immunotherapy: Part 2
    Judith Leibovici, Orit Itzhaki, Monica Huszar, Judith Sinai · 2011 · Immunotherapy
  57. Treatment of Infiltrative Basal Cell Carcinomas by inhibiting the Fibroblast Growth Factor (FGF)-Signal Transducer and Activator of Transcription (STAT)-3 Signalling Pathways
    Pedro Cuevas, J.C. Angulo, Adrián Cuevas-Bourdier, Irene Salgüero · 2012 · Journal of Cancer Science & Therapy
  58. Increased Activation and Differentiated Localization of Native and Phosphorylated STAT3 in Nasal Polyps
    Robert Linke, Ralph Pries, Michael Könnecke, KARL L. BRUCHHAGE, Robert Böscke, Maximilian Gebhard, Barbara Wollenberg · 2013 · International Archives of Allergy and Immunology
  59. Epithelial HO-1/STAT3 affords the protection of subanesthetic isoflurane against zymosan-induced lung injury in mice
    Ling Wang, Ya-Li Zhao, Ningning Liu, Zhu Xiao-shan, Qin-Qin Liu, Hai-Yu Mei, Angang Yang, Angang Yang, Chunfang Gao, Juntang Li · 2017 · Oncotarget
  60. Harnessing targeted protein degradation to potentiate cancer immunotherapy: from molecular mechanisms to delivery strategies
    Ye Liu, Ihsan Ullah, Youyong Yuan, Jun Wang · 2026 · Advanced Drug Delivery Reviews
  61. Identification of Potent siRNA Delivery Peptides Using Computer Modeling
    Ke Men, Mohan Liu, Xueyan Zhang, Yuling Yang, Rui Zhang, Yusi Wang, Die Hu, Bailing Zhou, Li Yang · 2024 · Advanced Science
  62. In-silico assessment of novel peptidomimetics inhibitor targeting STAT3 and STAT4 N-terminal domain dimerization: A comprehensive study using molecular docking, molecular dynamics simulation, and binding free energy analysis
    Megha Shree, Jayanti Vaishnav⧧, Gurudayal, Ravi Sankar Ampapathi⧧ · 2024 · Biochemical and Biophysical Research Communications
  63. Targeting STAT3 restores BRAF inhibitor sensitivity through miR-759-3p in human cutaneous melanoma cells.
    Yipeng Su, Ying Yu, Dongying He, Jinna Zhang, Zhiguo Wang, Pengfei Sun, Zhenyu Chen · 2018 · Europe PMC (PubMed Central)
  64. STAT3 as a Potential Target for Tumor Suppressive Effects of 15-Deoxy-δ12,14-prostaglandin J2 in Triple Negative Breast Cancer
    Su‐Jung Kim, Nam‐Chul Cho, Young‐Il Hahn, Seong Hoon Kim, Xizhu Fang, Young‐Joon Surh · 2021 · Journal of Cancer Prevention
  65. Azetidine ring, salicylic acid, and salicylic acid bioisosteres as determinants of the binding characteristics of novel potent compounds to Stat3
    Yue Chen, Ning Zhai, Yinsong Zhu, Peibin Yue, Nagendra Verma, Christine Brotherton‐Pleiss, Wenzhen Fu, Kayo Nakamura, Weiliang Chen, Joel K. Kawakami et al. · 2023 · Bioorganic & Medicinal Chemistry Letters
  66. Dienogest attenuates STAT3 activation in ovarian endometriotic cysts
    JongYeob Choi, MinWha Jo, Eunyoung Lee, Sung Eun Kim, Dong‐Yun Lee, DooSeok Choi · 2024 · European Journal of Obstetrics & Gynecology and Reproductive Biology
  67. Systematic Transcriptional Profiling of Responses to STAT1- and STAT3-Activating Cytokines in Different Cancer Types
    Mélanie Kirchmeyer, Florence Servais, Aurélien Ginolhac, Petr V. Nazarov, Christiane Margue, Demetra Philippidou, Nathalie Nicot, Iris Behrmann, Claude Haan, Stephanie Kreis · 2020 · Journal of Molecular Biology
  68. The New Model of Carcinogenesis: The Cancer Stem Cell Hypothesis
    Brenda Loaiza, Emilio Rojas, Mahara Valverde · 2012 · InTech eBooks
  69. STAT3 Nuclear Egress Requires Exportin 7 via Engaging Lysine Acetylation
    Andreas Herrmann Hua Yu · 2014 · MOJ Cell Science & Report
  70. Structure-activity relationship studies on O-alkylamino-tethered salicylamide derivatives with various amino acid linkers as potent anticancer agents
    Jimin Xu, Hye-Jin Kim, Jiabin Dong, Haiying Chen, Junhai Xu, Ruixia Ma, Mingxiang Zhou, Tianzhi Wang, Qiang Shen, Jia Zhou · 2022 · European Journal of Medicinal Chemistry
  71. Discovery of a potent C20-oxime pachysandra alkaloid analogue promising for treatment of hepatocellular carcinoma
    Chen‐Liang Zhao, Wen-Wen Zhang, Jinfeng Zhao, Jiang-Hai Ye, Wei Peng, Juan Zou, Kang He · 2025 · Bioorganic & Medicinal Chemistry
  72. Elucidation of Callistemon lanceolatus-derived natural compounds in STAT 3 pathway against human cancer cells: in silico and in vitro studies
    Mubashir Zafar, Sadaf Anwar, Malik Asif Hussain, Naveed Syed Iqbal, Abrar Ashraf Ali, Sadaf Sadaf, Mohammad Zeeshan Najm, Mohd Adnan Kausar · 2025 · Frontiers in Pharmacology
  73. Discovery of novel β-carboline/melatonin hybrids as STAT3 inhibitors for the treatment of lung cancer via increasing DNA damage
    Xiao‐Juan Yang, Shuting Jia, Chao Xia, Yuping Yang · 2025 · Bioorganic & Medicinal Chemistry
  74. Small Molecule Induces Time‐Dependent Inhibition of Stat3 Dimerization and DNA‐Binding Activity and Regresses Human Breast Tumor Xenografts
    Peibin Yue, Yue Chen, Monday Ogaba Ogese, Shan Sun, Xiaolei Zhang, Taiwo Esan, John K. Buolamwini, James Turkson · 2024 · ChemBioChem
  75. HOXB8 mediates resistance to cetuximab in colorectal cancer cells through activation of the STAT3 pathway
    Yunan Liang, Han Lin, Zongsheng Jiang, Qi Zhao, Ri Cui, Shaotang Li · 2024 · Discover Oncology
  76. Enhancing or eliminating signals for cell survival to treat disease.
    David John Tweardy, Naijie Jing · 2006 · PubMed
  77. Hunting for transcription factors: STAT3 decoy in non-small cell lung cancer
    Joseph Carmicheal, Sukhwinder Kaur, Surinder K. Batra, Apar Kishor Ganti · 2018 · Translational Lung Cancer Research
  78. Regulation of the Jak/STATs Pathways by Histone Deacetylases
    David Michael Woods, Maritza Lienlaf, Eduardo M. Sotomayor, Edward Seto, Alejandro Villagra · 2013 · Cancer drug discovery and develogment/Cancer drug discovery and development
  79. Identification of Niclosamide as a New Lead Compound to Suppress the Metastasis of Prostate Cancer Cells
    Ke Ding · 2014 · Medicinal Chemistry
  80. Computational Approaches in the Development of Small-molecule Transcription Factor Inhibitors
    Paul J. Jackson, Shirin Jamshidi, Doaa Boshra Farag · 2018 · Royal Society of Chemistry eBooks
  81. Expression of CD44highCD24Low cells, SOX2, and STAT3 transcription factors on peripheral blood and tumor tissue of penile squamous cell carcinoma
    Felipe Dubourcq de Barros, Gustavo Cardoso Guimarães, Mário Rino Martins, Felipe da Silva Marinho, Fernando Augusto Soares, Leuridan Cavalcante Torres · 2024 · Journal of Surgical Oncology
  82. Molecular Targets of Benzyl Isothiocyanates in Pancreatic Cancer
    Srinivas Reddy, C. Kartick, K. Sanjay · 2012 · InTech eBooks
  83. DHA is a newly defined STAT3 inhibitor that may be of multiple potential uses in cancer treatment
    2016 · Cancer Cell & Microenvironment
  84. STAT3 as a Major Contributor to Chemoresistance
    David S. Lee, Jennifer Rubin Grandis, Daniel E. Johnson · 2018 · Elsevier eBooks
  85. WITHDRAWN: Intrinsic molecular characteristics of inhibiting STAT3 activation and dimerization through targeting the phosphotyrosine binding site within the SH2 domain—A molecular dynamics study
    Yubo Fan, Ren Kong, David John Tweardy, Stephen T. C. Wong · 2013 · Journal of Structural Biology
  86. Upregulation of Blimp-1 in Human B Cells Plasma Cell Differentiation through IL-21 and CD40L Synergistically Promote
    B. Hilda Ye, B. Belinda Ding, Enguang Bi, Hongshan Chen, J. Jessica Yu · 2013
  87. Cell Density-Dependent Increase of Constitutive Signal Transducers and Activators of Transcription 3 Activity in Melanoma Cells Is Mediated
    Stephanie Kreis, Georg A. Munz, Serge Haan, Peter Claus Heinrich, Iris Behrmann · 2007
  88. DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF POTENTIAL STAT3 INHIBITORS AS ANTICANCER AGENTS
    D. Masciocchi · 2012 · Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano)
  89. Elucidating the role of mitochondrial-localized hepatocyte growth factor receptor in gastric oncogenesis
    Kae Hwan Sim · 2016
  90. Signal Transducer and Activation of Transcription 3: A Master Regulator of Myeloid-Derived Suppressor Cells
    K. Breckpot · 2016 · SpringerBriefs in immunology
  91. Novel Formulations of Antioxidant and Anti-inflammatory Drugs to Ameliorate Ischemic Damage Measured In Vitro
    Philip Liang · 2009 · TSpace (University of Toronto)
  92. Inhibitors of Stat3 (US)
    James Turkson, Andrew D. Hamilton · 2015 · Journal of International Crisis and Risk Communication Research
  93. Study Of The Egfr, Src And Stat3 Pathway In Pancreatic Cancer
    Soumya Jaganathan · 2010 · Journal of International Crisis and Risk Communication Research
  94. Role of STAT3 N-terminal domain and GAS-site recognition in signaling and crosstalk with STAT1 and NF-κB
    Antons Martincuks, G. Müller-Newen, B. Lüscher, M. Zenke · 2017 · RWTH Publications (RWTH Aachen)
  95. Targeting a Trigger: Platelet Derived Growth Factor Receptor Alpha in the Nodal Metastasis of Papillary Thyroid Cancer
    Ekpe Adewuyi · 2016 · ERA: Education and Research Archive (University of Alberta)
  96. Functional Characterization of Protein Tyrosine Phosphatases in Tumorigenesis through Substrate Identification
    Peng Zhang · 2013 · OhioLink ETD Center (Ohio Library and Information Network)
  97. Discovery and Optimization of Novel Small-molecular Inhibitors Suppressing Stat3-dependent Tumor Process
    Xiaolei Zhang · 2011 · Journal of International Crisis and Risk Communication Research
  98. STAT3 Inhibitors as Sensitizing Agents for Cancer Chemotherapy
    Yang Yang, Zhi Shi · 2019 · Elsevier eBooks
  99. Faculty Opinions recommendation of Cytokine response is determined by duration of receptor and signal transducers and activators of transcription 3 (STAT3) activation.
    Tsutomu Takeuchi, Hideto Kameda · 2013 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  100. PROGNOSTIC VALUE OF pSTAT3 EXPRESSION IN DIFFUSIVE B-LARGE CELL LYMPHOMA IN THE RUSSIAN PATIENT SAMPLE
    E. V. Vaneeva, V. A. Rosin, D. A. Dyakonov, S. V. Samarina, A. V. Rylov · 2019 · Сибирский научный медицинский журнал