The epigenome editors: How tools such as CRISPR offer new details about epigenetics

Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression

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Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers

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A Mammalian Histone Deacetylase Related to the Yeast Transcriptional Regulator Rpd3p

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Tetrahymena Histone Acetyltransferase A: A Homolog to Yeast Gcn5p Linking Histone Acetylation to Gene Activation

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Insulator dysfunction and oncogene activation in IDH mutant gliomas

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Editing DNA Methylation in the Mammalian Genome

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Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells

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CRISPR–Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome

Klann, T. S., Black, J. B., Chellappan, M., Safi, A., Song, L., Hilton, I. B., Crawford, G. E., Reddy, T. E., & Gersbach, C. A. (2017) · Nature Biotechnology · doi:10.1038/nbt.3853 · Cited by 447 · see citing works

Writing of H3K4Me3 overcomes epigenetic silencing in a sustained but context-dependent manner

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Gene-Specific Targeting of H3K9 Methylation Is Sufficient for Initiating Repression In Vivo

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Locus-specific epigenetic remodeling controls addiction- and depression-related behaviors

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CRISPR-mediated Activation of Latent HIV-1 Expression

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Targeted epigenetic editing of SPDEF reduces mucus production in lung epithelial cells

Song, J., Cano-Rodríguez, D., Winkle, M., Gjaltema, R. A. F., Goubert, D., Jurkowski, T. P., Heijink, I. H., Rots, M. G., & Hylkema, M. N. (2016) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00059.2016 · Cited by 50 · see citing works

Off-target effects in CRISPR/Cas9 gene editing

Guo, C., Ma, X., Gao, F., & Guo, Y. (2023) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2023.1143157 · Cited by 625 · see citing works

CRISPR/Cas9 gene-editing: Research technologies, clinical applications and ethical considerations

Memi, F., Ntokou, A., & Papangeli, I. (2018) · Seminars in Perinatology · doi:10.1053/j.semperi.2018.09.003 · Cited by 130 · see citing works

DNA methylation regulates the expression of the negative transcriptional regulators ID2 and ID4 during OPC differentiation

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Analysis of DNA modifications in aging research

Masser, D. R., Hadad, N., Porter, H. L., Stout, M. B., Unnikrishnan, A., Stanford, D. R., & Freeman, W. M. (2018) · GeroScience · doi:10.1007/s11357-018-0005-3 · Cited by 37 · see citing works

Optimizing CRISPR/Cas9 precision: Mitigating off-target effects for safe integration with photodynamic and stem cell therapies in cancer treatment

Merlin, J. P. J., & Abrahamse, H. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.117516 · Cited by 35 · see citing works

Epigenome editing by CRISPR/Cas9 in clinical settings: possibilities and challenges

Pei, W., Zhang, Y., Yin, T., & Yu, Y. (2019) · Briefings in Functional Genomics · doi:10.1093/bfgp/elz035 · Cited by 27 · see citing works

Blossom of CRISPR technologies and applications in disease treatment

Liu, H., Wang, L., & Luo, Y. (2018) · Synthetic and Systems Biotechnology · doi:10.1016/j.synbio.2018.10.003 · Cited by 19 · see citing works

Rethinking Parkinson's: The role of proteostasis networks and autophagy in disease progression

Sharma, A., Mannan, A., & Singh, T. G. (2025) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2025.104023 · Cited by 17 · see citing works

Introduction to the Virtual Issue Alcohol and Epigenetic Regulation: Do the Products of Alcohol Metabolism Drive Epigenetic Control of Gene Expression in Alcohol‐Related Disorders?

Vadigepalli, R., & Hoek, J. B. (2018) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.13630 · Cited by 14 · see citing works

The future of pediatric gene therapy: CRISPR-Cas9, AI, and personalized medicine

Pan, Y., Ding, J., Wang, W., Xu, D., Fan, J., & Zhang, W. (2026) · Pediatric Research · doi:10.1038/s41390-026-05270-3 · Cited by 2 · see citing works

A review on Epigenome Editing using CRISPR-based Tools to Rejuvenate Skin Tissues

Sichani, A. S., Baneshi, M., Ranjbar, M., Naeimzadeh, Y., & Fallahi, J. (2023) · International Journal of Bioinformatics and Intelligent Computing · doi:10.61797/ijbic.v2i2.234 · Cited by 1 · see citing works

Relieving the epigenetic blockade in progressive ms

Tiane, A. (2023) · doi:10.26481/dis.20230606at

The Bioethics of Inheritance

Waglawala, S. F., Singh, D. K., & Das, S. (2025) · Advances in computational intelligence and robotics book series · doi:10.4018/979-8-3373-5646-4.ch014

Differential roles of epigenetic regulators in the survival and differentiation of oligodendrocyte precursor cells

Egawa, N., Shindo, A., Hikawa, R., Kinoshita, H., Liang, A. C., Itoh, K., Lok, J. M., Maki, T., Takahashi, R., Lo, E. H., et al. (2018) · Glia · doi:10.1002/glia.23567 · Cited by 37 · see citing works

Epigenetic regulation of gene expression

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Mitochondrial DNA copy number is regulated in a tissue specific manner by DNA methylation of the nuclear-encoded DNA polymerase gamma A

Kelly, R. D., Mahmud, A., McKenzie, M., Trounce, I. A., & John, J. C. S. (2012) · Nucleic Acids Research · doi:10.1093/nar/gks770 · Cited by 193 · see citing works

Epigenetic gene expression and regulation

Huang, S., Litt, M. D., & Blakey, C. A. (2016) · Cited by 4 · see citing works

Epigenetic regulation of oligodendrocyte differentiation: From development to demyelinating disorders

Samudyata, S., Castelo‐Branco, G., & Liu, J. (2020) · Glia · doi:10.1002/glia.23820 · Cited by 31 · see citing works