Parkin ubiquitinates the α-synuclein–interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease

Chung, Kenny K.K., Zhang, Yi, Lim, Kah Leong, Tanaka, Yuji, Huang, Hui, Gao, Jun, Ross, Christopher A., Dawson, Valina L. +1 more·2001·Nature Medicine

DOI 10.1038/nm1001-1144

Cited by (744)

Items 201–300 of 744

Lewy Body–like Inclusions in Human Midbrain Organoids Carrying Glucocerebrosidase and α‐Synuclein Mutations
Junghyun Jo, Lin Yang, Hoang‐Dai Tran, Weonjin Yu, Alfred Xuyang Sun, Ya Yin Chang, Byung Chul Jung, Seung‐Jae Lee, Tzuen Yih Saw, Bin Xiao et al. · 2021 · Annals of Neurology
Crosstalk Between Macroautophagy and Chaperone-Mediated Autophagy: Implications for the Treatment of Neurological Diseases
Haijian Wu, Sheng Chen, Ammar Al-Baadani, Jie Xu, Qun Wu, Kum Pan, Jianmin Zhang, Yuan Hong · 2014 · Molecular Neurobiology
Parkin Ubiquitinates and Promotes the Degradation of RanBP2
Ji Won Um, Do Sik Min, Hyewhon Rhim, Jongsun Kim, Seung R. Paik, Kwang Chul Chung · 2005 · Journal of Biological Chemistry
Pathogenesis of familial Parkinson’s disease: new insights based on monogenic forms of Parkinson’s disease
Taku Hatano, Shinichiro Kubo, Shigeto Sato, Nobutaka Hattori · 2009 · Journal of Neurochemistry
Interaction between parkin and mutant glucocerebrosidase variants: a possible link between Parkinson disease and Gaucher disease
Idit Ron, D. Rapaport, Mia Horowitz · 2010 · Human Molecular Genetics
Parkin Regulates Mitosis and Genomic Stability through Cdc20/Cdh1
Seung Baek Lee, Jung Jin Kim, Hyun-Ja Nam, Bowen Gao, Ping Yin, Bo Qin, Sang Yeop Yi, Hyoungjun Ham, Debra L. Evans, Sun‐Hyun Kim et al. · 2015 · Molecular Cell
Down-regulation of α-synuclein expression can rescue dopaminergic cells from cell death in the substantia nigra of Parkinson’s disease rat model
Hiromi Hayashita‐Kinoh, Masanori YAMADA, Takanori Yokota, Yoshikuni Mizuno, Hideki Mochizuki · 2006 · Biochemical and Biophysical Research Communications
Synaptic vesicle trafficking and Parkinson's disease
Giovanni Esposito, Fernandes Ana Clara, Patrik Verstreken · 2011 · Developmental Neurobiology
Parkin protects dopaminergic neurons from excessive Wnt/β-catenin signaling
Nina Rawal, Olga Corti, Paola Sacchetti, Héctor Ardila-Osorio, Bita Sehat, Alexis Brice, Ernest Arenas · 2009 · Biochemical and Biophysical Research Communications
Parkin reverses intracellular β‐amyloid accumulation and its negative effects on proteasome function
Kenneth M. Rosen, Charbel Moussa, Hankyu Lee, Pravir Kumar, Tohru Kitada, Gangjian Qin, Qinghao Fu, Henry W. Querfurth · 2009 · Journal of Neuroscience Research
Triggering Aggresome Formation
Nava Zaarur, Anatoli B. Meriin, Vladimir L. Gabai, Michael Y. Sherman · 2008 · Journal of Biological Chemistry
Synphilin-1 attenuates neuronal degeneration in the A53T -synuclein transgenic mouse model
W. W. Smith, Zhong Wu Liu, Yajie Liang, Naoki Masuda, Deborah A. Swing, Nancy A. Jenkins, Neal G. Copeland, Juan Carlos Troncoso, Mikhail V. Pletnikov, Ted M. Dawson et al. · 2010 · Human Molecular Genetics
Molecular Features Underlying Neurodegeneration Identified through In Vitro Modeling of Genetically Diverse Parkinson’s Disease Patients
Lin Lin, Jonathan Göke, Engin Cukuroglu, Mark R. Dranias, Antonius M.J. VanDongen, Lawrence Walter Stanton · 2016 · Cell Reports
Loss of Parkin contributes to mitochondrial turnover and dopaminergic neuronal loss in aged mice
Sachiko Noda, Shigeto Sato, Takahiro Fukuda, Norihiro Tada, Yasuo Uchiyama, Keiji Tanaka, Nobutaka Hattori · 2019 · Neurobiology of Disease
Caspase-1 and Caspase-8 Cleave and Inactivate Cellular Parkin
Søren Kahns, Michaël Kalai, Lene Diness Jakobsen, Brian F.C. Clark, Peter Vandenabeele, Poul Henning Jensen · 2003 · Journal of Biological Chemistry
Genetic contributions to Parkinson's disease
Yue Ming Huang, Linda Cheung, Dominic B. Rowe, Glenda Margaret Halliday · 2004 · Brain Research Reviews
Protein interaction networks in neurodegenerative diseases: From physiological function to aggregation
Gaetano Calabrese, Cristen M. Molzahn, Thibault Mayor · 2022 · Journal of Biological Chemistry
Identification of Common Biological Pathways and Drug Targets Across Multiple Respiratory Viruses Based on Human Host Gene Expression Analysis
Steven B. Smith, William Dampier, Aydın Tözeren, James R. Brown, Michal Magid-Slav · 2012 · PLoS ONE
Inclusion Body Formation and Neurodegeneration Are Parkin Independent in a Mouse Model of α-Synucleinopathy
Rainer von Coelln, Bobby Thomas, Shaida A. Andrabi, Kah Leong Lim, Joseph M. Savitt, Roya Saffary, Wanda L.H. Stirling, Kristy J. Bruno, Ellen J. Hess, Michael K. Lee et al. · 2006 · Journal of Neuroscience
Nosology of Parkinson’s Disease: Looking for the Way Out of a Quackmire
Mark S. Forman, Virginia M.‐Y. Lee, John Q. Trojanowski · 2005 · Neuron
Genes associated with Parkinson syndrome
Saskia Biskup, Manfred Gerlach, Andreas R. Kupsch, Heinz Reichmann, Peter Franz Riederer, P. Vieregge, Ullrich Wüllner, Thomas Gasser · 2008 · Journal of Neurology
Parkinson-related parkin reduces α-Synuclein phosphorylation in a gene transfer model
Preeti J. Khandelwal, Sonya B. Dumanis, Li Feng, Kathleen A. Maguire‐Zeiss, George William Rebeck, Hilal Ahmed Lashuel, Charbel Moussa · 2010 · Molecular Neurodegeneration
Astrocytic but not neuronal increased expression and redistribution of parkin during unfolded protein stress
María Dolores Ledesma, Cristian A. Galván, Bianca Hellias, Carlos G. Dotti, Poul Henning Jensen · 2002 · Journal of Neurochemistry
K63-linked ubiquitination and neurodegeneration
Kah‐Leong Lim, Grace G.Y. Lim · 2010 · Neurobiology of Disease
The effects of oxidative stress on parkin and other E3 ligases
Matthew J. LaVoie, Giuseppe P. Cortese, Beth L. Ostaszewski, Michael G. Schlossmacher · 2007 · Journal of Neurochemistry
Does Impairment of the Ubiquitin-Proteasome System or the Autophagy-Lysosome Pathway Predispose Individuals to Neurodegenerative Disorders such as Parkinson's Disease?
Noriyuki Matsuda, Keiji Tanaka · 2010 · Journal of Alzheimer s Disease
Convergence of Parkin, PINK1, and α-Synuclein on Stress-induced Mitochondrial Morphological Remodeling
Kristi L. Norris, Rui Hao, Liangfu Chen, Chun-Hsiang Lai, Meghan Kapur, Peter J. Shaughnessy, Dennis Chou, Jin Yan, J. Paul Taylor, Simone Engelender et al. · 2015 · Journal of Biological Chemistry
Models of Parkinson's disease
Michael Orth, Sarah J. Tabrizi · 2003 · Movement Disorders
Differential expression of alpha-synuclein, parkin, and synphilin-1 isoforms in Lewy body disease
Katrin Beyer, Montserrat Domingo-Sàbat, Jordi Humbert, Cristina Carrato, Isidró Ferrer, Aurelio Ariza · 2008 · Neurogenetics
Interaction between Parkin and α-Synuclein in PARK2-Mediated Parkinson’s Disease
Daniel Aghaie Madsen, Sissel Ida Schmidt, Morten Blaabjerg, Morten Meyer · 2021 · Cells
Prolyl-isomerase Pin1 Accumulates in Lewy Bodies of Parkinson Disease and Facilitates Formation of α-Synuclein Inclusions
Akihide Ryo, Takashi Togo, Toshiki Nakai, Akiko Hirai, Mayuko Nishi, Akira Yamaguchi, Kyoko Suzuki, Yoshio Hirayasu, Hideki Kobayashi, Kilian Perrem et al. · 2005 · Journal of Biological Chemistry
The role of the ubiquitin-proteasomal pathway in Parkinson's disease and other neurodegenerative disorders
Kenny K. K. Chung, Valina Lynn Dawson, Ted M. Dawson · 2001 · Trends in Neurosciences
Parkin Protects against Mitochondrial Toxins and β-Amyloid Accumulation in Skeletal Muscle Cells
Kenneth M. Rosen, Vimal Veereshwarayya, Charbel Moussa, Qinghao Fu, Matthew S. Goldberg, Michael G. Schlossmacher, Jie Shen, Henry W. Querfurth · 2006 · Journal of Biological Chemistry
Progress in the pathogenesis and genetics of Parkinson's disease
Yoshikuni Mizuno, Nobutaka Hattori, Shinichiro Kubo, Shigeto Sato, Kenya Nishioka, Taku Hatano, Hiroyuki Tomiyama, Manabu Funayama, Yutaka Machida, Hideki Mochizuki · 2008 · Philosophical Transactions of the Royal Society B Biological Sciences
The C289G and C418R missense mutations cause rapid sequestration of human Parkin into insoluble aggregates
Wen‐Jie Gu, Olga Corti, Francisco Araujo, Cornelia Hampe, Sandrine Jacquier, Christoph B. Lücking, N. Abbas, Charles J. Duyckaerts, Thomas Rooney, Laurent Pradier et al. · 2003 · Neurobiology of Disease
Endoplasmic reticulum-associated protein degradation
Ernst Jarosch, Uwe Lenk, Thomas Sommer · 2002 · International review of cytology
Role of Ubiquitin–Proteasome and Autophagy-Lysosome Pathways in α-Synuclein Aggregate Clearance
Subhashree Sahoo, Amrita Arpita Padhy, Varsha Kumari, Parul Mishra · 2022 · Molecular Neurobiology
Parkin Regulation and Neurodegenerative Disorders
Chengwu Zhang, Liting Hang, Tso‐Pang Yao, Kah‐Leong Lim · 2016 · Frontiers in Aging Neuroscience
Parkin is recruited into aggresomes in a stress-specific manner: over-expression of parkin reduces aggresome formation but can be dissociated from parkin's effect on neuronal survival
Miratul M. K. Muqit · 2003 · Human Molecular Genetics
Basic Fibroblast Growth Factor Protects against Rotenone-Induced Dopaminergic Cell Death through Activation of Extracellular Signal-Regulated Kinases 1/2 and Phosphatidylinositol-3 Kinase Pathways
Shih‐Ling Hsuan, Heather M. Klintworth, Zhengui Xia · 2006 · Journal of Neuroscience
The Contribution of α -Synuclein Spreading to Parkinson’s Disease Synaptopathy
Francesca Longhena, Gaia Faustini, Cristina Missale, Marina Pizzi, PierFranco Spano, Arianna Bellucci · 2017 · Neural Plasticity
Molecular pathogenesis of Parkinson's disease: update
Shinji Saiki, Shigeto Sato, Nobutaka Hattori · 2011 · Journal of Neurology Neurosurgery & Psychiatry
Mitochondrial Dynamics and Parkinson's Disease: Focus on Parkin
Kah‐Leong Lim, Xiao‐Hui Ng, Lim Gui-Yin Grace, Tso‐Pang Yao · 2011 · Antioxidants and Redox Signaling
Dorfin Localizes to Lewy Bodies and Ubiquitylates Synphilin-1
Takashi Ito, Jun-ichi Niwa, Nozomi Hishikawa, Shinsuke Ishigaki, Manabu Doyu, Gen Sobue · 2003 · Journal of Biological Chemistry
Proteasome Failure Promotes Positioning of Lysosomes around the Aggresome via Local Block of Microtubule-Dependent Transport
Nava Zaarur, Anatoli B. Meriin, Eloy Bejarano, Xiaobin Xu, Vladimir L. Gabai, Ana María Cuervo, Michael Y. Sherman · 2014 · Molecular and Cellular Biology
Redefining Non-Motor Symptoms in Parkinson’s Disease
Laura Peña-Zelayeta, Karen M. Delgado-Minjares, Marcos M. Villegas-Rojas, Karen León‐Arcia, Alberto Santiago-Balmaseda, Jesús Andrade-Guerrero, Isaac Pérez-Segura, Emmanuel Ortega‐Robles, Luis Oskar Soto-Rojas, Óscar Arias-Carrión · 2025 · Journal of Personalized Medicine
Parkin interacts with LIM Kinase 1 and reduces its cofilin-phosphorylation activity via ubiquitination
Meng K. Lim, Takeshi Kawamura, Yosuke Ohsawa, Masafumi Ohtsubo, Shuichi Asakawa, Atsushi Takayanagi, Nobuyoshi Shimizu · 2007 · Experimental Cell Research
Parkin and defective ubiquitination in Parkinson’s disease
Ted M. Dawson · 2006 · Springer eBooks
A Product of the Human Gene Adjacent to parkin Is a Component of Lewy Bodies and Suppresses Pael Receptor-induced Cell Death
Yuzuru Imai, Mariko Soda, Tetsuro Murakami, Mikio Shoji, Koji Abe, Ryōsuke Takahashi · 2003 · Journal of Biological Chemistry
Parkinson’s Disease and Cognitive Impairment
Yang Yang, Beisha Tang, Jifeng Guo · 2016 · Parkinson s Disease
Melatonin and Parkinson Disease: Current Status and Future Perspectives for Molecular Mechanisms
Omid Reza Tamtaji, Russel Joseph Reiter, Reza Alipoor, Ehsan Dadgostar, Ebrahim Kouchaki, Zatollah Asemi · 2019 · Cellular and Molecular Neurobiology
Parkin is recruited to the centrosome in response to inhibition of proteasomes
Jinghui Zhao, Yong Ren, Qian Jiang, Jian Feng · 2003 · Journal of Cell Science
Common anti-apoptotic roles of parkin and α-synuclein in human dopaminergic cells
Yutaka Machida, Tomoki Chiba, Atsushi Takayanagi, Yoshikazu Tanaka, Masato Asanuma, Norio Ogawa, Akihiko Koyama, Takeshi Iwatsubo, Shosuke Ito, Poul Hening Jansen et al. · 2005 · Biochemical and Biophysical Research Communications
The multi‐faceted role of mitochondria in the pathology of Parkinson’s disease
Dennison Trinh, Ahmad R. Israwi, Lindsay R. Arathoon, Jacqueline A. Gleave, Joanne E. Nash · 2020 · Journal of Neurochemistry
The role of amyloids in Alzheimer's and Parkinson's diseases
Parveen Salahuddin, Munazza Tamkeen Fatima, Vladimir Nikolaevich Uversky, Rizwan Hasan Khan, Zeyaul Islam, Mohammad Furkan · 2021 · International Journal of Biological Macromolecules
Membrane trafficking in neuronal maintenance and degeneration
Dong Wang, Chih‐Chiang Chan, Smita Cherry, P. Robin Hiesinger · 2012 · Cellular and Molecular Life Sciences
Subthalamic oscillatory activity and connectivity during gait in Parkinson's disease
Franz Hell, Annika Plate, Jan Hinnerk Mehrkens, Kai Bötzel · 2018 · NeuroImage Clinical
Multiple system atrophy: An update
Gregor Karl Wenning, Felix Geser, Michaela Stampfer‐Kountchev, Fran�ois Tison · 2003 · Movement Disorders
The ubiquitin–proteasome system and neurodegenerative disorders
Robert Layfield, James S Lowe, Lynn Bedford · 2005 · Essays in Biochemistry
Decline of striatal dopamine release in parkin‐deficient mice shown by ex vivo autoradiography
Shigeto Sato, Tomoki Chiba, Shingo Nishiyama, Takeharu Kakiuchi, Hideo Tsukada, Taku Hatano, Takahiro Fukuda, Yasunobu Yasoshima, Nobuyuki Kai, Kazuto Kobayashi et al. · 2006 · Journal of Neuroscience Research
Involvement of Endoplasmic Reticulum Stress on the Cell Death Induced by 6-Hydroxydopamine in Human Neuroblastoma SH-SY5Y Cells
Yamamuro, Akiko, Yoshioka, Yasuhiro, Ogita, Kiyokazu, Maeda, Sadaaki · 2006 · Neurochemical Research
NLRP3 Inflammasomes in Parkinson’s disease and their Regulation by Parkin
Yiqun Yan, Yi Fang, Ran Zheng, Jiali Pu, Baorong Zhang · 2020 · Neuroscience
Mutations in PRKN and SNCA Genes Important for the Progress of Parkinson’s Disease
Anna Oczkowska, Wojciech P. Kozubski, Margarita Lianeri, Jolanta Dorszewska · 2014 · Current Genomics
Residual substantia nigra neuromelanin in Parkinson’s disease is cross-linked to α-synuclein
Mauro Fasano, Sabrina Giraudo, Silvia Coha, Bruno Bergamasco, Leonardo Lopiano · 2003 · Neurochemistry International
Inflammatory Mediators Leading to Protein Misfolding and Uncompetitive/Fast Off‐Rate Drug Therapy for Neurodegenerative Disorders
Stuart A. Lipton, Zezong Gu, Tomohiro Nakamura · 2007 · International review of neurobiology
Environmental neurotoxic chemicals-induced ubiquitin proteasome system dysfunction in the pathogenesis and progression of Parkinson's disease
F SUN, A.G. KANTHASAMY, V. ANANTHARAM, A.G. KANTHASAMY · 2007 · Pharmacology & Therapeutics
Part I: Parkin-associated proteins and Parkinson's disease
Kumlesh Kumar Dev · 2003 · Neuropharmacology
Aberrant Alternative Splicing Events in Parkinson's Disease
Ru‐Huei Fu, Shih‐Ping Liu, Shyh-Jer Huang, Hung‐Jen Chen, Pin-Ru Chen, Ya-Hsien Lin, Yu‐Chen Ho, Wen-Lin Chang, Chang‐Hai Tsai, Woei‐Cherng Shyu et al. · 2013 · Cell Transplantation
Regulation of Parkin E3 ubiquitin ligase activity
Helen Walden, R.J. Martinez-Torres · 2012 · Cellular and Molecular Life Sciences
Intracellular delivery of Parkin rescues neurons from accumulation of damaged mitochondria and pathological α-synuclein
eunna chung, Youngsil Choi, Jiae Park, Wonheum Nah, Jae-Hyung Park, Yukdong Jung, Joonno Lee, Hyunji Lee, So‐Young Park, Sun‐Young Hwang et al. · 2020 · Science Advances
Neuroprotective Effect of Curcumin on the Nigrostriatal Pathway in a 6-Hydroxydopmine-Induced Rat Model of Parkinson’s Disease is Mediated by α7-Nicotinic Receptors
Eslam El Nebrisi, Hayate Javed, Shreesh Kumar Ojha, Murat Öz, Safa A. S. Shehab · 2020 · International Journal of Molecular Sciences
Pro‐apoptotic protein glyceraldehyde‐3‐phosphate dehydrogenase promotes the formation of Lewy body‐like inclusions
Katsumi Tsuchiya, Hisao Tajima, Toyoyasu Kuwae, Takao Takeshima, Toshiya Nakano, Masaharu Tanaka, Katsuyoshi Sunaga, Yōko Fukuhara, Kenji Nakashima, Eisaku Ohama et al. · 2005 · European Journal of Neuroscience
Nanozyme enabled protective therapy for neurological diseases
Fangyi Cheng, Sumasri Kotha, Miao Fu, Qi Yang, Heng Wang, Weiwei He, Xiaobo Mao · 2024 · Nano Today
MPTP and DSP-4 susceptibility of substantia nigra and locus coeruleus catecholaminergic neurons in mice is independent of parkin activity
Bobby Thomas, Rainer von Coelln, Allen S. Mandir, Daniel B. Trinkaus, Mohamed H. Farah, Kah Leong Lim, Noel Ylagan Calingasan, M. Flint Beal, Valina Lynn Dawson, Ted M. Dawson · 2007 · Neurobiology of Disease
Loss of parkin promotes lipid rafts-dependent endocytosis through accumulating caveolin-1: implications for Parkinson’s disease
Seon‐Heui Cha, Yu Ree Choi, Cheol Ho Heo, Seo‐Jun Kang, Eun-hye Joe, Ilo Jou, Hwan-Myung Kim, Sang Myun Park · 2015 · Molecular Neurodegeneration
Neurotoxicity and behavioral deficits associated with Septin 5 accumulation in dopaminergic neurons
Jin H. Son, Hibiki Kawamata, Myung Sik Yoo, Dae Joon Kim, Young K. Lee, Soo‐Youl Kim, Ted M. Dawson, Hui Zhang, David Sulzer, Lichuan Yang et al. · 2005 · Journal of Neurochemistry
THE DOPAMINERGIC NIGROSTRIATAL SYSTEMAND PARKINSON'S DISEASE
Mojgan Hodaie, Joseph Samir Neimat, Andrés M. Lozano · 2007 · Neurosurgery
The Role of Ubiquitin-Protein Ligases in Neurodegenerative Disease
H.C. Ardley, Philip Alan Robinson · 2004 · Neurodegenerative Diseases
Genetic screens in Caenorhabditis elegans models for neurodegenerative diseases
Olga Sin, Helen Michels, Ellen A. A. Nollen · 2014 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Parkin-Dependent Degradation of the F-Box Protein Fbw7β Promotes Neuronal Survival in Response to Oxidative Stress by Stabilizing Mcl-1
Susanna Ekholm‐Reed, Matthew S. Goldberg, Michael G. Schlossmacher, Steven I. Reed · 2013 · Molecular and Cellular Biology
Parkinson's disease: one biochemical pathway to fit all genes?
Rejko Krüger, Olaf Eberhardt, Olaf Rieß, Jörg Bernhard Schulz, Olaf Rieß · 2002 · Trends in Molecular Medicine
Conjugation and deconjugation of ubiquitin regulating the destiny of proteins
Kwang‐Hyun Baek · 2003 · Experimental & Molecular Medicine
α-Synuclein overexpression during manganese-induced apoptosis in SH-SY5Y neuroblastoma cells
Yan Li, Liguang Sun, Tongjian Cai, Ying Zhang, Shijie Lv, Yu Wang, Liping Ye · 2009 · Brain Research Bulletin
Parkinson’s Disease: A Complex Interplay of Mitochondrial DNA Alterations and Oxidative Stress
Sarah Ciccone, Emiliano Maiani, Giovanna Bellusci, Marc F. Diederich, Stefania Gonfloni · 2013 · International Journal of Molecular Sciences
NUB1 Suppresses the Formation of Lewy Body-Like Inclusions by Proteasomal Degradation of Synphilin-1
Kunikazu Tanji, Tomoaki Tanaka, Fumiaki Mori, Katsumi Kito, Hitoshi Takahashi, Koichi Wakabayashi, Tetsu Kamitani · 2006 · American Journal Of Pathology
Accumulation of Misfolded Protein Through Nitrosative Stress Linked to Neurodegenerative Disorders
Takashi Uehara · 2007 · Antioxidants and Redox Signaling
Activation mechanisms of the E3 ubiquitin ligase parkin
Nikhil Panicker, Valina Lynn Dawson, Ted M. Dawson · 2017 · Biochemical Journal
Alpha-synuclein at the intracellular and the extracellular side: functional and dysfunctional implications
Denis Ottolini, Tito Calí, Ildikò Szabó, Marisa Brini · 2016 · Biological Chemistry
Dimerization of Parkinson's disease-causing DJ-1 and formation of high molecular weight complexes in human brain
Stéphanie Baulac, Matthew J. LaVoie, Jennifer Mae Strahle, Michael G. Schlossmacher, Weiming Xia · 2004 · Molecular and Cellular Neuroscience
N-Acetylcysteine and Celecoxib Lessen Cadmium Cytotoxicity Which Is Associated with Cyclooxygenase-2 Up-regulation in Mouse Neuronal Cells
Maria E. Figueiredo‐Pereira, Zongmin Li, Marlon Jansen, Patricia Rockwell · 2002 · Journal of Biological Chemistry
The Role of Alpha-Synuclein and Other Parkinson’s Genes in Neurodevelopmental and Neurodegenerative Disorders
C. Alejandra Morato Torres, Zinah Wassouf, Faria Zafar, Danuta Sastre, Tiago F. Outeiro, Birgitt Schüle · 2020 · International Journal of Molecular Sciences
Cross‐functional E3 ligases Parkin and C‐terminus Hsp70‐interacting protein in neurodegenerative disorders
Pravir Kumar, Kaveri Pradhan, Karunya Ramani, Rashmi K. Ambasta, Henry W. Querfurth · 2011 · Journal of Neurochemistry
Mechanisms of Parkinson’s disease-related proteins in mediating secondary brain damage after cerebral ischemia
TaeHee Kim, Raghu Vemuganti · 2017 · Journal of Cerebral Blood Flow & Metabolism
Parkinson's disease‐associated protein Parkin: an unusual player in cancer
Juan Liu, Cen Zhang, Wenwei Hu, Zhaohui Feng · 2018 · 癌症：英文版
Parkinson's disease: from causes to mechanisms
Olga Corti, Cornelia Hampe, Frederic D. Darios, Pablo Ibáñez, Merle Ruberg, Alexis Brice · 2004 · Comptes Rendus Biologies
LRRK2 in Parkinson’s disease: biochemical functions
Vasanti S. Anand, Steven P. Braithwaite · 2009 · FEBS Journal
Oxidative Stress Mechanisms Underlying Parkinson’s Disease-Associated Neurodegeneration in C. elegans
Sudipta Chakraborty, Julia Bornhorst, Thuy Nguyen, Michael Aschner · 2013 · International Journal of Molecular Sciences
The role of ubiquitin linkages on α‐synuclein induced‐toxicity in a Drosophila model of Parkinson’s disease
Francesca K. M. Lee, Azaria Kam Yan Wong, Yuk Wa Lee, Oi Wan Wan, Ho Yin Edwin Chan, Kenny K. K. Chung · 2009 · Journal of Neurochemistry
The ubiquitin ligase E6‐AP promotes degradation of α‐synuclein
Shalaka A. Mulherkar, Jaiprakash Sharma, Nihar Ranjan Jana · 2009 · Journal of Neurochemistry
Parkin contributes to synaptic vesicle autophagy in Bassoon-deficient mice
Sheila Hoffmann-Conaway, Marisa M. Brockmann, Katharina Schneider, Anil Annamneedi, Kazi Atikur Rahman, Christine Bruns, Kathrin Textoris‐Taube, Thorsten Trimbuch, Karl‐Heinz Smalla, Christian Rosenmund et al. · 2020 · eLife