The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1H-NMR-based metabonomics
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Atherosclerosis--an inflammatory disease
Ross, R. (1999) · New England Journal of Medicine · doi:10.1056/nejm199901143400207 · Cited by 21,725
Research works printed but not linked: 18
- Kjelsberg, M.O., Cutler, J.A. & Dolecek, T.A. Brief description of the Multiple Risk Factor Intervention Trial. Am. J. Clin. Nutr. 65 (Suppl. 1), 191S–195S (1997). · DOI
- Kuller, L.H. et al. Cigarette smoking and mortality. MRFIT Research Group. Prev. Med. 20, 638–654 (1991). · DOI
- Multiple Risk Factor Intervention Trial Research Group. Relationship between baseline risk factors and coronary heart disease and total mortality in the Multiple Risk Factor Intervention Trial. Prev. Med. 15, 254–273 (1986). · DOI
- McIlvain, H.E., McKinney, M.E., Thompson, A.V. & Todd, G.L. Application of the MRFIT smoking cessation program to a healthy, mixed-sex sample. Am. J. Prev. Med. 8, 165–170 (1992). · DOI
- Cullen, P., Funke, H., Schulte, H. & Assmann, G. Lipoproteins and cardiovascular risk—from genetics to CHD prevention. Eur. Heart J. 19 (Suppl. C), C5–C11 (1998).
- Isles, C.G. & Paterson, J.R. Identifying patients at risk for coronary heart disease: Implications from trials of lipid-lowering drug therapy. Q.J. Med. 93, 567–574 (2000). · DOI
- Nicholson, J.K., Lindon, J.C. & Holmes, E. 'Metabonomics': Understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data. Xenobiotica 29, 1181–1189 (1999). · DOI · Paper page
- Nicholson, J.K. & Wilson, I.D. High resolution proton magnetic resonance spectroscopy of biological fluids Prog. Nucl. Magn. Reson. Spectrosc. 21, 449–501 (1989). · DOI · Paper page
- Lindon, J.C., Holmes, E. & Nicholson, J.K. Pattern recognition methods and applications in biomedical magnetic resonance. Prog. Nucl. Magn. Reson. Spectrosc. 39, 1–40 (2001). · DOI · Paper page
- Lindon, J.C., Nicholson, J.K.N., Holmes, E. & Everett, J.R. Metabonomics: metabolic processes studied by NMR spectroscopy of biofluids. Concepts Magn. Reson. 12, 289–320 (2000). · DOI · Paper page
- Holmes, E. et al. Chemometric models for toxicity classification based on NMR spectra of biofluids. Chem. Res. Toxicol. 13, 471–478 (1999). · DOI · Paper page
- Storck, T., von Brevern, M.C., Behrens, C.K., Scheel, J. & Bach, A. Transcriptomics in predictive toxicology. Curr. Opin. Drug Discov. Devel. 5, 90–97 (2002).
- Nicholson, J.K., Foxall, P.J., Spraul, M., Farrant, D.R. & Lindon, J.C. 750 MHz 1H and 1H-13C NMR spectroscopy of human blood plasma. Anal. Chem. 67, 793–811 (1995). · DOI · Paper page
- Ala-Korpela, M. 1H-NMR spectroscopy of human blood plasma. Prog. Nucl. Magn. Reson. Spectrosc. 27, 475–554 (1995). · DOI · Paper page
- Eriksson, L., Johansson, E., Kettanah-Wold, N. & Wold, S. Introduction to Multi and Megavariate Data Analysis Using Projection Methods (PCA and PLS-DA) (Umetrics AB, Malmo, Sweden, 1999).
- Wold, S., Antti, H., Lindgren, F. & Ohman, J. Orthogonal signal correction of near-infrared spectra. Chemometrics Intelligent Lab. Systems 44, 175–185 (1998). · DOI · Paper page
- Ala-Korpela, M., Hiltunen, Y. & Bell, J.D. Quantification of biomedical NMR data using artificial neural network analysis: Lipoprotein lipid profiles from 1H NMR data of human plasma. NMR Biomed. 8, 235–244 (1995). · doi:10.1002/nbm.1940080603
- Otvos, J. In Handbook of Lipoprotein Testing (eds. Rifai, N., Warnick, R. & Dominiczak, M.) 497–508 (AACC Press, Washington DC, 1997).
Cited by
Beckonert, O., Keun, H. C., Ebbels, T. M. D., Bundy, J., Holmes, E., Lindon, J. C., & Nicholson, J. K. (2007) · Nature Protocols · doi:10.1038/nprot.2007.376 · Cited by 2,109
Self-citationExhaled breath condensate: methodological recommendations and unresolved questions
Horváth, I., Hunt, J., & Barnes, P. J. (2005) · European Respiratory Journal · doi:10.1183/09031936.05.00029705 · Cited by 1,284
Gut microorganisms, mammalian metabolism and personalized health care
Nicholson, J. K., Holmes, E., & Wilson, I. D. (2005) · Nature Reviews Microbiology · doi:10.1038/nrmicro1152 · Cited by 945
Self-citationThe gut microbiota modulates host energy and lipid metabolism in mice
Velagapudi, V. R., Hezaveh, R., Reigstad, C. S., Gopalacharyulu, P., Yetukuri, L., Islam, S., Felin, J., Perkins, R., Borén, J., Orešič, M., et al. (2010) · Journal of Lipid Research · doi:10.1194/jlr.m002774 · Cited by 589
Scalbert, A., Brennan, L., Fiehn, O., Hankemeier, T., Kristal, B. S., van Ommen, B., Pujos-Guillot, E., Verheij, E., Wishart, D., & Wopereis, S. (2009) · Metabolomics · doi:10.1007/s11306-009-0168-0 · Cited by 565
Metadata
- Authors
- Brindle, J. T., Antti, H., Holmes, E., Tranter, G., Nicholson, J. K., Bethell, H. W. L., Clarke, S., Schofield, P. M., McKilligin, E., Mosedale, D. E., & Grainger, D. J.
- Venue
- Nature Medicine
- Published
- 2002-11-25
- Volume
- 8
- Issue
- 12
- Pages
- 1439-1445
- ISSN
- 1078-8956 (ISSN-L)
- 1546-170X
- OpenAlex
- W2130382164
- Cited by
- 1,029
- References
- 1
- FWCI
- 12.20
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- www.springer.com/tdm (vor)
- www.springer.com/tdm (unspecified)
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1H-NMR-based metabonomics. https://app.cochat.ai/papers/10.1038/nm1202-802
- The paper
- Brindle, J. T., Antti, H., Holmes, E., Tranter, G., Nicholson, J. K., Bethell, H. W. L., Clarke, S., Schofield, P. M., McKilligin, E., Mosedale, D. E., & Grainger, D. J. (2002). Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1H-NMR-based metabonomics. Nature Medicine. https://doi.org/10.1038/nm1202-802
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
