Genomic instability in laminopathy-based premature aging

Liu, Baohua, Wang, Jianming, Chan, Kui Ming, Tjia, Wai Mui, Deng, Wen, Guan, Xinyuan, Huang, Jian-dong, Li, Kai Man +13 more·2005·Nature Medicine

Cited by (644)

Items 501–600 of 644

  1. Impact of MnTBAP and Baricitinib Treatment on Hutchinson–Gilford Progeria Fibroblasts
    Elena Vehns, Rouven Arnold, Karima Djabali · 2022 · Pharmaceuticals
  2. Progeria‐based vascular model identifies networks associated with cardiovascular aging and disease
    Mzwanele Ngubo, Zhaoyi Chen, Darin McDonald, Rana Karimpour, Amit Shrestha, Julien Yockell‐Lelièvre, Aurélie Laurent, Ojong Tabi Ojong Besong, Eve Chung Tsai, Francis Jeffrey Dilworth et al. · 2024 · Aging Cell
  3. Targeting CK2 eliminates senescent cells and prolongs lifespan in Zmpste24-deficient mice
    Jie Zhang, Pengfei Sun, Zhuping Wu, Jie Wu, Jiali Jia, Haoman Zou, Yanzhen Mo, Zhongjun Zhou, Baohua Liu, Ying Ao et al. · 2024 · Cell Death and Disease
  4. Mechanotransduction of the vasculature in Hutchinson-Gilford Progeria Syndrome
    Kevin L. Shores, George A. Truskey · 2024 · Frontiers in Physiology
  5. Validation of metaxin-2 deficient C. elegans as a model for MandibuloAcral Dysplasia associated to mtx-2 (MADaM) syndrome
    Chloé Talarmin, Georges Smolyakov, Cleo Parisi, Cyril Scandola, Valérie Andrianasolonirina, Cloé Lecoq, Valentine Houtart, Song-Hua Lee, Homa Adle‐Biassette, Bénédicte Thiébot et al. · 2024 · Communications Biology
  6. Mutational and expressional alterations of ZMPSTE24, DNA damage response-related gene, in gastric and colorectal cancers
    Ju Hwa Lee, Nam Jin Yoo, Min Sung Kim, Chang Hyeok An, Sug Hyung Lee · 2016 · Pathology - Research and Practice
  7. Comprehensive analysis of expression and prognosis for LMNB family genes in human sarcoma
    Gen Wu, Qunyan Tian, Jie Liu, Qiong Zhou, Dazhi Zou, Ziyuan Chen, Tong Wu, Wanchun Wang, Xia Hong, Jian Zhou · 2022 · Medicine
  8. HiIDDD: a high-throughput imaging pipeline for the quantitative detection of DNA damage in primary human immune cells
    Kelsey L. Gallant, Arsun Bektas, Mary Kaileh, Ana Lustig, Luigi Ferrucci, Gianluca Pegoraro, Tom Misteli · 2022 · Scientific Reports
  9. Base editor repairs mutation found in the premature-ageing syndrome progeria
    Wilbert P. Vermeij, Jan H.J. Hoeijmakers · 2021 · Nature
  10. Lamin A/C as a Molecular Link Between Nuclear Organization, Chromatin Dynamics, and Tumor Progression
    Cecilia Foglini, Katia Scotlandi, Michela Pasello · 2026 · Cells
  11. Elevated Levels of Lamin A Promote HR and NHEJ-Mediated Repair Mechanisms in High-Grade Ovarian Serous Carcinoma Cell Line
    Duhita Sengupta, Asima Mukhopadhyay, Kaushik Sengupta · 2023 · Cells
  12. From loss to gain: role for SUN1 in laminopathies
    Baohua Liu, Dong‐Yan Jin, Zhongjun Zhou · 2012 · Cell & Bioscience
  13. Laminopathies
    Tomás McKenna, Jean‐Ha Baek, Maria Eriksso · 2013 · InTech eBooks
  14. Mechanisms of vascular aging: What can we learn from Hutchinson-Gilford progeria syndrome?
    Lara del Campo, Magda R. Hamczyk, Vicente Andrés, José Martínez‐González, Cristina Rodrı́guez · 2018 · Clínica e Investigación en Arteriosclerosis (English Edition)
  15. Le vieillissement
    Paula Fontanilla-Ramirez, Simon Willaume, Benoît Thezé, Angela Moussa, Gaëlle Pennarun, Pascale Bertrand · 2020 · médecine/sciences
  16. A multiparametric anti-aging CRISPR screen uncovers a role for BAF in protein synthesis regulation
    Sophia Y. Breusegem, Jack W. Houghton, Raquel Romero-Bueno, Adrián Fragoso-Luna, Katherine A. Kentistou, Ken K. Ong, Anne F. J. Janssen, Nicholas A. Bright, Christian G. Riedel, John R. B. Perry et al. · 2025 · Nature Communications
  17. Improving Senescent Wound Healing With Local and Systemic Therapies
    Caroline Szpalski, Parag Butala, Meredith T. Vandegrift, Denis Knobel, Robert Johnson Allen, Pierre B. Saadeh, Stephen M. Warren · 2018 · Annals of Plastic Surgery
  18. Hutchinson-Gilford progeria syndrome cardiovascular disease and oxidative stress
    Vicente Andrés · 2011 · Frontiers in Bioscience-Scholar
  19. The Mechanism and Potential Therapeutic Strategies of Vascular Aging
    Wanzhou Wu, Xuan Wang, Fangfang Wu, Xiao‐Tian Yan, Yongping Bai · 2025 · Aging Medicine
  20. VPS4B orchestrates response to nuclear envelope stress by regulating ESCRT-III dynamics in glioblastoma
    Zuqian Wu, Issei Omura, Atsushi Saito, Kazunori Imaizumi, Yasunao F. Kamikawa · 2024 · Nucleus
  21. Lamin A/C and PI(4,5)P2—A Novel Complex in the Cell Nucleus
    Sara Escudeiro-Lopes, Vlada Filimonenko, Lenka Jarolimová, Pavel Hozák · 2024 · Cells
  22. Decoding DNA repair regulation across human lifespan variability
    Yunjia Tang, Dekai Zhang, Kaiyan Wang, Zhiyong Mao, Yu Chen · 2025 · Ageing Research Reviews
  23. The Nuclear Envelope in Cardiac Health and Disease
    Daniel Brayson, Catherine M. Shanahan · 2015 · Springer eBooks
  24. Progeria Mouse Models
    Pablo Mayoral, Clea Bárcena, Carlos López-Otı́n · 2018 · Elsevier eBooks
  25. Stem Cell Aging
    Primož J. Rožman, Katerina Jazbec, Mojca Jež · 2018 · InTech eBooks
  26. Biochemistry and Cell Biology of Ageing: Part III Biomedical Science
    J. Robin Harris, Viktor I. Korolchuk · 2023 · Sub-cellular biochemistry/Subcellular biochemistry
  27. Impact of Senolytic Treatment on Gene Expression in Aged Lung
    Soo Jung Cho, Alexander Pronko, Jianjun Yang, Heather W. Stout-Delgado · 2023 · International Journal of Molecular Sciences
  28. Cell and Molecular Aging
    Priyamvada Rai, Bruce Robert Troen · 2011 · Springer eBooks
  29. A decade of understanding spatio-temporal regulation of DNA repair by the nuclear architecture
    Hicham Saad, Jennifer A. Cobb · 2016 · Biochemistry and Cell Biology
  30. 1, Structural and Functional Studies of Human Replication Protein A; 2 DNA Damage Responses and DNA Repair Defects in Laminopathy-Based Premature Aging.
    Yiyong Liu · 2007 · Digital Commons - East Tennessee State University (East Tennessee State University)
  31. Emerging Molecular Connections between NM23 Proteins, Telomeres and Telomere-Associated Factors: Implications in Cancer Metastasis and Ageing
    Shalu Sharma, Antara Sengupta, Shantanu Chowdhury · 2021 · International Journal of Molecular Sciences
  32. Mechanisms of genome instability in Hutchinson-Gilford progeria
    Haoyue Zhang, Kan Cao · 2016 · Frontiers in Biology
  33. Regulation of NSL by TAF4A is critical for genome stability and quiescence of muscle stem cells
    Angelina M. Georgieva, Krishna Sreenivasan, Dong Ding, Clémentine Villeneuve, Sara A. Wickström, Stefan Günther, Carsten Tobias Kuenne, Ulrich Gärtner, Xinyue Guo, Yonggang Zhou et al. · 2025 · Nature Communications
  34. The cardiac 4D nucleome: nuclear and chromatin dynamics across development, disease and ageing
    Yinuo Wang, Gergana D. Dobreva · 2026 · Nature Reviews Cardiology
  35. Microbiome at sites of gingival recession in children with Hutchinson–Gilford progeria syndrome
    Seyed Hossein Bassir, Isabelle I. Chase, Bruce J. Paster, Leslie B. Gordon, Monica E. Kleinman, Mark W. Kieran, David M. Kim, Andrew L. Sonis · 2018 · Journal of Periodontology
  36. DNA Repair, Human Diseases and Aging
    Vaidehi Krishnan, Baohua Liu, Zhongjun Zhou · 2011 · InTech eBooks
  37. Molecular Basis of Progeroid Diseases
    Ian García‐Aguirre, Feliciano Monterrubio-Ledezma, Alma Alamillo‐Iniesta, Susana Castro‐Obregón, Bulmaro Cisneros · 2020 · Springer eBooks
  38. Epigenetic Significance of Chromatin Organization During Cellular Aging and Organismal Lifespan
    Milena Georgieva, Dessislava Staneva, George A. Miloshev · 2016 · Springer eBooks
  39. Human Diseases Related to Nuclear Envelope Proteins
    Howard J. Worman · 2016 · Springer eBooks
  40. Lesion complexity drives age related cancer susceptibility in human mammary epithelial cells
    Deepa Sridharan, Shiena Enerio, Mark A. LaBarge, Martha R. Stampfer, Janice M. Pluth · 2017 · Aging
  41. Senolytics Target Senescent Cells and Improve Aging and Age-Related Diseases
    Tony Buffard, Gerardo Ferbeyre · 2020 · Healthy ageing and longevity
  42. Aging: Reading, Reasoning, and Resolving Using Drosophila as a Model System
    Nisha Nisha, Kritika Raj, Pragati, Shweta Tandon, Soram Idiyasan Chanu, Surajit Sarkar · 2020 · Springer eBooks
  43. DNA repair-related genes and adipogenesis: Lessons from congenital lipodystrophies
    Julliane Tamara Araújo de Melo Campos, Matheus Sena de Oliveira, Luisa Pessoa Soares, Katarina Azevedo de Medeiros, Leonardo René dos Santos Campos, Josivan Gomes Lima · 2022 · Genetics and Molecular Biology
  44. Mouse Models of Accelerated Aging
    Jan Vijg, Paul Hasty · 2006 · Elsevier eBooks
  45. Curriculum Vitae Personal Data
    Dávid Selmeczi · 2008
  46. NSL complex acetylates Lamin A/C
    Varvara V. Popova, Jerry L. Workman · 2019 · Nature Cell Biology
  47. Matrix Stiffening Induces Mechanical Memory and Nuclear Fragility in Cardiomyocytes via Microtubule-Lamin Coupling
    Nesrine Bouhrira, Sebastian Pizarro, Victor Senf, Kenneth B. Margulies · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  48. Progerin expression in humans: Implications for natural ageing
    So‐mi Kang, Soyoung Park, Tae-Gyun Woo, Bae-Hoon Kim, Bum-Joon Park · 2026 · Mechanisms of Ageing and Development
  49. Homoharringtonine exhibits senotherapeutic activity that mitigates diet- and age-associated obesity and insulin resistance and extends lifespan in mice
    Eok-Cheon Kim, Han-Byul Jung, Yu-kyoung Park, Youlim Son, Hye-Na Cha, Yash Patel, Ju Hee Lee, Minah Choi, Soyoung Park, Il-Kug Kim et al. · 2026 · Nature Communications
  50. TRF2 enriched cytoplasmic chromatin drives cGAS-STAT1-mediated inflammation in senescence
    Renuka Kandhaya‐Pillai, Hee Yeon Kim, Jakub Belhadj, Julia M. Sidorova, Tamar Tchkonia, James L. Kirkland, Junko Oshima · 2026 · iScience
  51. When lamin A/C fails, the heart suffers.
    Jop H. van Berlo · 2006 · PubMed Central
  52. Chromatin Signaling in Aging and Cellular Senescence
    Florence Couteau, Frédérick A. Mallette · 2016 · Elsevier eBooks
  53. Cellular and Molecular Aging
    Priyamvada Rai, Bruce Robert Troen · 2017 · Springer eBooks
  54. Dermatoses with Minimal Epidermal Changes
    Thuy L. Phung, Teresa S. Wright, Crystal Y. Pourciau, Bruce Robert Smoller · 2017 · Springer eBooks
  55. A-type lamins and Hutchinson-Gilford progeria syndrome pathogenesis and therapy
    Vicente Andrés · 2011 · Frontiers in Bioscience-Scholar
  56. Understanding of stem cells in bone biology and translation into clinical applications
    Peng Liu, Zhipeng Fan, Songlin Wang · 2010 · Frontiers in Biology
  57. The pathological role of adipose tissue aging in the progression of systemic insulin resistance
    Yohko Yoshida, Ippei Shimizu, Tohru Minamino · 2015 · Inflammation and Regeneration
  58. Hutchinson-Gilford progeria syndrome
    S L Davies, J. Bozzo · 2006 · Drugs of the Future
  59. Integration of Biochemical and Mechanical Signals at the Nuclear Periphery: Impacts on Skin Development and Disease
    Rachel M. Stewart, Megan C. King, Valerie Horsley · 2018 · Stem cell biology and regenerative medicine
  60. Results-I. Lamin A is an Endogenous Activator of SIRT6 in DNA Damage Repair Process
    Shrestha Ghosh · 2019 · Springer theses
  61. Mesenchymal Stem Cell-Mediated Therapy of Peripheral Artery Disease Is Stimulated by a Lamin A-Progerin Binding Inhibitor
    Soon Chul Heo, Yang Woo Kwon, Gyu Tae Park, Sang‐Mo Kwon, Sun Sik Bae, Bum-Joon Park, Jae Ho Kim · 2020 · Journal of Lipid and Atherosclerosis
  62. Higher-Order Unfolding of Peri/Centric Satellite Heterochromatin is an Early and Consistent Event in Cell Senescence: A Dissertation
    Eric C Swanson · 2014 · The Journal of the American Medical Association (JAMA) Network (American Medical Association)
  63. Genetic and acquired lipodystrophies: from fat redistribution to insulin resistance and aging
    Jacqueline Capeau, Jocelyne Magré, Martine Caron, Claire Lagathu, Jean‐Philippe Bastard, Corinne Vigouroux · 2006 · Future Lipidology
  64. Molecular Mechanisms Underlying Cardiometabolic Disease in Aging
    Víctor Fanjul · 2019
  65. The Mi-2 Homolog Mit1 Actively Positions Nucleosomes Within Heterochromatin to Suppress Transcription
    Kevin M. Creamer · 2014
  66. Nuclear mechanostability emerges from satellite DNA condensation into chromocenters
    Franziska Brändle, Benjamin Frühbauer, Ilaria Ceppi, Logan de Monchaux-Irons, Thor van Heesch, Alessia Sommer, Francesco Rivetti, Sung Sik Lee, Chiara Morelli, Paolo Arosio et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  67. Translational Research: Gene, Pharmacogenomics and Cell-Based Therapy in the Aging Heart
    José Marı́n-Garcı́a, Michael J. Goldenthal, Gordon Willy Pak Ling Moe · 2007 · Springer eBooks
  68. Development of a mouse model for Hutchinson-Gilford progeria syndrome reveal defects in adult stem cell maintenance
    Ylva Rosengardten · 2011 · Figshare
  69. Novel Roles for A-Type Lamins in Maintaining Genomic Stability
    Abena B. Redwood · 2012 · Open Scholarship Institutional Repository (Washington University in St. Louis)
  70. The genomic anchors of the human major histocompatibility complex
    Diego Ottaviani · 2009 · OpenGrey (Institut de l'Information Scientifique et Technique)
  71. Transcriptional Functions of DNA Repair Proteins Involved in Premature Aging
    Robin Assfalg, Sebastian Ibe · 2011 · InTech eBooks
  72. Myouclear Breakdown in Sporadic Inclusion Body Myositis
    Satoshi Nakano, Hirofumi Kusak · 2011 · InTech eBooks
  73. Nucleo-cytoskeletal interactions in the mechanical functioning of the cell
    Frederik Houben · 2011
  74. Rb Inactivation Leads to E2F1-mediated DNA Double Strand Break Accumulation: A Dissertation
    Mary Pickering · 2006 · The Journal of the American Medical Association (JAMA) Network (American Medical Association)
  75. A New Pathway Responsible For 53BP1 Loss in Breast Cancer and Laminopathies
    David A Grotsky · 2012 · Open Scholarship Institutional Repository (Washington University in St. Louis)
  76. The role of lamin A and emerin in mediating genome organisation
    Lauren S. Godwin · 2010 · Brunel University Research Archive (BURA) (Brunel University London)
  77. Molecular studies of Hutchinson-Gilford progeria syndrome
    Hanna Sagelius · 2009 · Figshare
  78. Influence of repair proteins and chromatin modifiers on mobility of DNA double-strand breaks induced by heavy ion irradiation
    Linda Carmen Annabelle Becker · 2014 · GSI Repository (German Federal Government)
  79. Envoltura nuclear, laminopatías y envejecimiento acelerado
    Dámaso Crespo Santiago, Laura Alonso, Vicente González‐Quintanilla, Rosario Verduga Vélez, Carlos Fernández Viadero · 2007 · Revista Española de Geriatría y Gerontología
  80. Identification of Markers for Cellular Stress and Senescence in Laminopathic Cells by Proteomic Analysis
    Kirti Sinha, Cherukuvada V. Brahmendra Swamy, Bh. Muralikrishna, M. M. Idris, R. Nagaraj, Veena K. Parnaik · 2014 · Revista de Fomento Social
  81. Mouse models for understanding the molecular mechanism of bone disease in Hutchinson-Gilford progeria syndrome
    Éva Schmidt · 2011 · Figshare
  82. MOLECULAR AND CELLULAR MECHANISMS CONTRIBUTING TO THE ACCELERATED AGING PHENOTYPE IN HUTCHINSON-GILFORD PROGERIA SYNDROME
    Dan Constantinescu · 2008 · D-Scholarship@Pitt (University of Pittsburgh)
  83. Human Premature Aging Diseases
    Dai-Di Gan, Mohammad A. Hedayati, Tinna Stevnsner, Vilhelm A. Bohr · 2007 · Springer eBooks
  84. Contemporary Reviews in Cardiovascular Medicine Cellular Senescence, Vascular Disease, and Aging Part 1 of a 2-Part Review
    Jason Ciril Kovacic, Elizabeth G. Nabel · 2016
  85. Une farnésylation persistante aux conséquences dramatiques
    Claire Laure Navarro, Yannick Poitelon, Nicolas Lévy · 2008
  86. Identification and characterization of senescence-associated microRNAs in a mouse model of the XFE progeroid syndrome
    Lolita S. Nidadavolu · 2013 · D-Scholarship@Pitt (University of Pittsburgh)
  87. Progeria and Genome Instability
    Fanbiao Meng, Baohua Liu, Zhongjun Zhou · 2015 · Springer eBooks
  88. Influence of repair proteins and chromatin modifiers on mobility of DNA double-strand breaks induced by heavy ion irradiation Einflüsse von Reparaturproteinen und Chromatinmodifikationen auf die Bewegung von DNA Doppelstrangbrüchen nach Schwerionenbestrahlung
    Linda Carmen, Annabelle Becker · 2014
  89. Methods to Monitor DNA Repair Defects and Genomic Instability in the Context of a Disrupted Nuclear Lamina
    Susana Gonzalo, Raymond J. Kreienkamp · 2016 · Methods in molecular biology
  90. Targeted Strategies to Fight Cardiac Aging
    José Marı́n-Garcı́a · 2014 · Elsevier eBooks
  91. A-type lamins preserve genomic stability
    Ignacio González-Suárez, Susana Gonzalo · 2010
  92. Nuclear Domains and DNA Repair
    Jordan B. Pinder, Alkmini Kalousi, Evi Soutoglou, Graham Dellaire · 2016 · Springer eBooks
  93. Role of the nuclear lamina for stem cell mediated homeostasis
    Roman Petrovsky · 2016
  94. Altered regulation of adipogenesis with respect to disease processes
    Stephanie J. Davies · 2017 · Cork Open Research Archive (University College Cork, Ireland)
  95. Characterization of the topology, targeting and binding properties of SUN proteins and their involvement in laminopathies
    Farhana Haque · 2011 · Figshare
  96. The Role of Nej1-Lif1 in Double Strand Break Repair Pathway Choice and Non-Homologous End-Joining
    Kyle Sorenson · 2017 · Libraries and Cultural Resources (University of Calgary)
  97. Molecular dissection of A-type lamin-regulated pathways
    Tobias Corne · 2017 · Ghent University Academic Bibliography (Ghent University)
  98. Genetics of Progeria and Aging
    Wong Ken S.K., Zhongjun Zhou · 2018 · Elsevier eBooks
  99. Generation and characterization of a new conditional mouse model of Hutchinson-Gilford Progeria Syndrome to assess disease progression upon progerin suppression and lamin A restoration
    Amanda Sánchez‐López · 2020
  100. Alteration of epigenetic landscape by lamin A mutations: Hallmark of Dilated Cardiomyopathy
    Avinanda Banerjee, Kaushik Sengupta · 2020 · bioRxiv (Cold Spring Harbor Laboratory)