Genomic instability in laminopathy-based premature aging

Cited by (644)

Items 201–300 of 644

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  7. Prelamin A impairs 53BP1 nuclear entry by mislocalizing NUP153 and disrupting the Ran gradient
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  8. Barrier-to-autointegration factor 1 (Banf1) regulates poly [ADP-ribose] polymerase 1 (PARP1) activity following oxidative DNA damage
    Emma Bolderson, Joshua T. Burgess, Jun Li, Neha S. Gandhi, Didier Boucher, Laura V. Croft, Samuel Beard, Jennifer Plowman, Amila Suraweera, Mark N. Adams et al. · 2019 · Nature Communications
  9. Loss of MTX2 causes mandibuloacral dysplasia and links mitochondrial dysfunction to altered nuclear morphology
    Sahar Elouej, Karim Harhouri, Morgane Le Mao, Geneviève Baujat, Sheela Nampoothiri, Hülya Kayserili, Nihal M. Al Menabawy, Laila Selim, Arianne Llamos Paneque, Christian Kubisch et al. · 2020 · Nature Communications
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  16. Prelamin A accumulation in endothelial cells induces premature senescence and functional impairment
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  17. Premature aging disorders: A clinical and genetic compendium
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  20. Cadmium toxicity in diazotrophic Anabaena spp. adjudged by hasty up-accumulation of transporter and signaling and severe down-accumulation of nitrogen metabolism proteins
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  21. The Laminopathies and the Insights They Provide into the Structural and Functional Organization of the Nucleus
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  22. Partial lipodystrophy with severe insulin resistance and adult progeria Werner syndrome
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  23. Mouse Models and Aging
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  27. Lamin B1 sequesters 53BP1 to control its recruitment to DNA damage
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  29. Defective DSB repair correlates with abnormal nuclear morphology and is improved with FTI treatment in Hutchinson-Gilford progeria syndrome fibroblasts
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  30. Mammalian telomeres and their partnership with lamins
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  32. Progerin sequestration of PCNA promotes replication fork collapse and mislocalization of XPA in laminopathy‐related progeroid syndromes
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  37. Lamin A/C impairments cause mitochondrial dysfunction by attenuating PGC1α and the NAMPT-NAD+ pathway
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  38. Heterochromatin loss as a determinant of progerin‐induced DNA damage in Hutchinson–Gilford Progeria
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  40. The Role of the Nuclear Lamina in Cancer and Apoptosis
    Jos L. V. Broers, Frans C. S. Ramaekers · 2014 · Advances in experimental medicine and biology
  41. Nuclear Lamins and Oxidative Stress in Cell Proliferation and Longevity
    Takeshi Shimi, Robert D. Goldman · 2014 · Advances in experimental medicine and biology
  42. Basic and translational aging research in China: present and future
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  43. Kansl1 haploinsufficiency impairs autophagosome-lysosome fusion and links autophagic dysfunction with Koolen-de Vries syndrome in mice
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  44. A role for SUV39H1-mediated H3K9 trimethylation in the control of genome stability and senescence in WI38 human diploid lung fibroblasts
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  45. Molecular Genetics of Autosomal-Recessive Axonal Charcot-Marie-Tooth Neuropathies
    Rafaëlle Bernard, Annachiara De Sandre‐Giovannoli, Valérie Delague, Nicolas Lévy · 2006 · NeuroMolecular Medicine
  46. Prelamin A mediates myocardial inflammation in dilated and HIV-associated cardiomyopathies
    Daniel Brayson, Andrea Frustaci, Romina Verardo, Cristina Chimenti, Matteo Antonio Russo, Robert Hayward, Sadia Ahmad, Gema Vizcay‐Barrena, Andrea Protti, Peter S. Zammit et al. · 2019 · JCI Insight
  47. Post-Translational Modification of Lamins: Mechanisms and Functions
    Mingyue Zheng, Guoxiang Jin, Zhongjun Zhou · 2022 · Frontiers in Cell and Developmental Biology
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    Veena K. Parnaik, Kaliyaperumal Manju · 2006 · Journal of Biosciences
  49. A-type lamins and Hutchinson-Gilford progeria syndrome: pathogenesis and therapy
    M. Gonzalez Jose · 2011 · Frontiers in Bioscience-Scholar
  50. Metformin alleviates ageing cellular phenotypes in Hutchinson–Gilford progeria syndrome dermal fibroblasts
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  51. Combined loss of LAP1B and LAP1C results in an early onset multisystemic nuclear envelopathy
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  52. A‐type lamins and signaling: The PI 3‐kinase/Akt pathway moves forward
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  53. Chromosome mis-segregation triggers cell cycle arrest through a mechanosensitive nuclear envelope checkpoint
    Solène Hervé, Andrea Scelfo, Gabriele Bersano Marchisio, Marine Grison, Kotryna Vaidžiulytė, Marie Dumont, Annapaola Angrisani, Adib Keikhosravi, Gianluca Pegoraro, Mathieu Deygas et al. · 2025 · Nature Cell Biology
  54. Rapamycin As an Antiaging Therapeutic?: Targeting Mammalian Target of Rapamycin to Treat Hutchinson–Gilford Progeria and Neurodegenerative Diseases
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  60. Hypoxia-Induced Degenerative Protein Modifications Associated with Aging and Age-Associated Disorders
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  65. SIRT7 couples light-driven body temperature cues to hepatic circadian phase coherence and gluconeogenesis
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  66. Lamin A/C recruits ssDNA protective proteins RPA and RAD51 to stalled replication forks to maintain fork stability
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