Genomic instability in laminopathy-based premature aging
Liu, Baohua, Wang, Jianming, Chan, Kui Ming, Tjia, Wai Mui, Deng, Wen, Guan, Xinyuan, Huang, Jian-dong, Li, Kai Man, Chau, Pui Yin, Chen, David J, Pei, Duanqing, Pendas, Alberto M, Cadiñanos, Juan, López-Otín, Carlos, Tse, Hung Fat, Hutchison, Chris, Chen, Junjie, Cao, Yihai, Cheah, Kathryn S E, Tryggvason, Karl, Zhou, Zhongjun·2005·Nature Medicine
DOI 10.1038/nm1266
Cited by (644)
Items 201–300 of 644
- Causes and consequences of genomic instability in laminopathies: Replication stress and interferon responseSimona Graziano, Ray Kreienkamp, Núria Coll-Bonfill, Susana Gonzalo · 2018 · Nucleus
- In the middle of it all: Mutual mechanical regulation between the nucleus and the cytoskeletonKris Noel Dahl, Elizabeth A. Booth-Gauthier, Benoît Ladoux · 2009 · Journal of Biomechanics
- NuMA promotes homologous recombination repair by regulating the accumulation of the ISWI ATPase SNF2h at DNA breaksPierre‐Alexandre Vidi, Jing Liu, Daniela Correia Salles, Swaathi Jayaraman, George Dorfman, Matthew Gray, Patricia C. Abad, Prabhas V. Moghe, Joseph Irudayaraj, Lisa Wiesmüller et al. · 2014 · Nucleic Acids Research
- Dietary magnesium supplementation improves lifespan in a mouse model of progeriaRicardo Villa‐Bellosta · 2020 · EMBO Molecular Medicine
- Lamin A/C, laminopathies and premature ageing.Baohua Liu, Zhongjun Zhou · 2008 · PubMed
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- Prelamin A impairs 53BP1 nuclear entry by mislocalizing NUP153 and disrupting the Ran gradientAndrew M. Cobb, Delphine Larrieu, Derek T Warren, Yiwen Liu, Sonal Srivastava, Andrew J. O. Smith, Richard Peter Bowater, Stephen P. Jackson, Catherine M. Shanahan · 2016 · Aging Cell
- Barrier-to-autointegration factor 1 (Banf1) regulates poly [ADP-ribose] polymerase 1 (PARP1) activity following oxidative DNA damageEmma Bolderson, Joshua T. Burgess, Jun Li, Neha S. Gandhi, Didier Boucher, Laura V. Croft, Samuel Beard, Jennifer Plowman, Amila Suraweera, Mark N. Adams et al. · 2019 · Nature Communications
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- Fight to the bitter end: DNA repair and agingYu Chen, Anke Geng, Weina Zhang, Zhen Yu Qian, Xiaoping Wan, Ying Jiang, Zhiyong Mao · 2020 · Ageing Research Reviews
- Ageing nucleus gets out of shapeHannes Lans, Jan H.J. Hoeijmakers · 2006 · Nature
- Genomic instability and DNA replication defects in progeroid syndromesBurla, Romina, La Torre, Mattia, Merigliano, Chiara, Vernì, Fiammetta, Saggio, Isabella · 2018 · Nucleus
- Inner nuclear membrane proteins: impact on human diseaseIván Méndez-López, Howard J. Worman · 2012 · Chromosoma
- The Histone Demethylase Jumonji Coordinates Cellular Senescence Including Secretion of Neural Stem Cell–Attracting CytokinesPatrick M. Perrigue, Michael E. Silva, Charles Warden, Nathan L. Feng, Michael A. Reid, Daniel J. Mota, Lauren P. Joseph, Yangzi Isabel Tian, Carlotta A. Glackin, Margarita Gutova et al. · 2015 · Molecular Cancer Research
- B-type lamins in health and diseaseChristopher J. Hutchison · 2014 · Seminars in Cell and Developmental Biology
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- Premature aging disorders: A clinical and genetic compendiumFranziska Schnabel, Uwe Kornak, Bernd Wollnik · 2020 · Clinical Genetics
- Chromosome organisation during ageing and senescenceTamir Chandra, Kristina Kirschner · 2016 · Current Opinion in Cell Biology
- p53 Isoforms in Cellular Senescence- and Ageing-Associated Biological and Physiological FunctionsKaori Fujita · 2019 · International Journal of Molecular Sciences
- Cadmium toxicity in diazotrophic Anabaena spp. adjudged by hasty up-accumulation of transporter and signaling and severe down-accumulation of nitrogen metabolism proteinsPrashant Kumar Singh, Alok Kumar Shrivastava, Antra Chatterjee, Sarita Pandey, Snigdha Rai, Shilpi Singh, L.C. Rai · 2015 · Journal of Proteomics
- The Laminopathies and the Insights They Provide into the Structural and Functional Organization of the NucleusXianrong Wong, Colin L. Stewart · 2020 · Annual Review of Genomics and Human Genetics
- Partial lipodystrophy with severe insulin resistance and adult progeria Werner syndromeBruno Donadille, Pascal D’anella, Martine Auclair, Nancy A. Uhrhammer, Marc Sorel, R Grigorescu, Sophie Ouzounian, Gilles Cambonie, Pierre Boulot, Pascal Laforêt et al. · 2013 · Orphanet Journal of Rare Diseases
- Mouse Models and AgingChen‐Yu Liao, Brian Keith Kennedy · 2014 · Current topics in developmental biology/Current Topics in Developmental Biology
- ZMPSTE24, an integral membrane zinc metalloprotease with a connection to progeroid disordersJemima Barrowman, Susan Michaelis · 2009 · Biological Chemistry
- DNA repair and PARP in agingAlexander Bürkle · 2006 · Free Radical Research
- The farnesylated nuclear proteins KUGELKERN and LAMIN B promote aging‐like phenotypes in Drosophila fliesAnnely Brandt, Georg Krohne, Jörg Großhans · 2008 · Aging Cell
- Lamin B1 sequesters 53BP1 to control its recruitment to DNA damageEtourneaud, Laure, Moussa, Angela, Rass, Emilie, Genet, Diane, Willaume, Simon, Chabance-Okumura, Caroline, Wanschoor, Paul, Picotto, Julien, Thézé, Benoît, Dépagne, Jordane et al. · 2021 · Science Advances
- Reprogramming progeria fibroblasts re‐establishes a normal epigenetic landscapeZhaoyi Chen, Wing Y. Chang, Alton Etheridge, Hilmar Strickfaden, Zhigang Jin, Gareth Palidwor, Ji‐Hoon Cho, Kai Wang, Sarah Y. Kwon, Carole Doré et al. · 2017 · Aging Cell
- Defective DSB repair correlates with abnormal nuclear morphology and is improved with FTI treatment in Hutchinson-Gilford progeria syndrome fibroblastsDan Constantinescu, Antonei Benjamin Csoka, Christopher S. Navara, Gerald P. Schatten · 2010 · Experimental Cell Research
- Mammalian telomeres and their partnership with laminsRomina Burla, Mattia La Torre, Isabella Saggio · 2016 · Nucleus
- Embryonic Senescence and Laminopathies in a Progeroid Zebrafish ModelEriko Koshimizu, Shintaro Imamura, Jie Qi, Jamal Toure, Delgado M. Valdez, Christopher E. Carr, Jun‐ichi Hanai, Shuji Kishi · 2011 · PLoS ONE
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- Hutchinson-Gilford Progeria Syndrome: Cellular Mechanisms and Therapeutic PerspectivesBulmaro Cisneros, Ian García‐Aguirre, Marlon De Ita, Isabel Arrieta‐Cruz, Haydeé Rosas‐Vargas · 2023 · Archives of Medical Research
- Premature aging syndromes: From patients to mechanismMattheus Xing Rong Foo, Peh Fern Ong, Oliver Dreesen · 2019 · Journal of Dermatological Science
- The central role of chromatin maintenance in agingGianluca Pegoraro, Tom Misteli · 2009 · Aging
- Eukaryotic gene regulation in three dimensions and its impact on genome evolutionM. Madan Babu, Sarath Chandra Janga, Ines de Santiago, Ana Pombo · 2008 · Current Opinion in Genetics & Development
- Lamin A/C impairments cause mitochondrial dysfunction by attenuating PGC1α and the NAMPT-NAD+ pathwayScott Maynard, Arnaldur Hall, Panagiotis Galanos, Salvatore Rizza, Tatsuro Yamamoto, Helena Hagner Gram, Sebastian Howen Nesgaard Munk, Muhammad Shoaib, Claus Storgaard Sørensen, Vilhelm A. Bohr et al. · 2022 · Nucleic Acids Research
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- The cell nucleus and aging: tantalizing clues and hopeful promisesScaffidi, Paola, Gordon, Leslie, Misteli, Tom · 2005 · PLoS Biology
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- Nuclear Lamins and Oxidative Stress in Cell Proliferation and LongevityTakeshi Shimi, Robert D. Goldman · 2014 · Advances in experimental medicine and biology
- Basic and translational aging research in China: present and futureMajor Program Expert Group, Xiaojuan He, Moshi Song, Jing Tao Qu, Yansu Guo, Heqi Cao, Ruijuan Sun, Guang‐Hui Liu, Yong Shen · 2019 · Protein & Cell
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- Molecular Genetics of Autosomal-Recessive Axonal Charcot-Marie-Tooth NeuropathiesRafaëlle Bernard, Annachiara De Sandre‐Giovannoli, Valérie Delague, Nicolas Lévy · 2006 · NeuroMolecular Medicine
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- Post-Translational Modification of Lamins: Mechanisms and FunctionsMingyue Zheng, Guoxiang Jin, Zhongjun Zhou · 2022 · Frontiers in Cell and Developmental Biology
- Laminopathies: Multiple disorders arising from defects in nuclear architectureVeena K. Parnaik, Kaliyaperumal Manju · 2006 · Journal of Biosciences
- A-type lamins and Hutchinson-Gilford progeria syndrome: pathogenesis and therapyM. Gonzalez Jose · 2011 · Frontiers in Bioscience-Scholar
- Metformin alleviates ageing cellular phenotypes in Hutchinson–Gilford progeria syndrome dermal fibroblastsSeul‐Ki Park, Ok Sarah Shin · 2017 · Experimental Dermatology
- Combined loss of LAP1B and LAP1C results in an early onset multisystemic nuclear envelopathyBoris Fichtman, Fadia Zagairy, Nitzan Biran, Yiftah Barsheshet, Elena Chervinsky, Ziva Ben Neriah, Avraham Shaag, Michael Assa, Orly N Elpeleg, Amnon Harel et al. · 2019 · Nature Communications
- A‐type lamins and signaling: The PI 3‐kinase/Akt pathway moves forwardSandra Marmiroli, Jessika Bertacchini, Francesca Beretti, Vittoria Cenni, Marianna Guida, Anto De Pol, Nadir M. Maraldi, Giovanna Lattanzi · 2009 · Journal of Cellular Physiology
- Chromosome mis-segregation triggers cell cycle arrest through a mechanosensitive nuclear envelope checkpointSolène Hervé, Andrea Scelfo, Gabriele Bersano Marchisio, Marine Grison, Kotryna Vaidžiulytė, Marie Dumont, Annapaola Angrisani, Adib Keikhosravi, Gianluca Pegoraro, Mathieu Deygas et al. · 2025 · Nature Cell Biology
- Rapamycin As an Antiaging Therapeutic?: Targeting Mammalian Target of Rapamycin to Treat Hutchinson–Gilford Progeria and Neurodegenerative DiseasesAndrew R. Mendelsohn, James W. Larrick · 2011 · Rejuvenation Research
- Nuclear damages and oxidative stress: new perspectives for laminopathiesGiovanna Lattanzi, Sandra Marmiroli, A. Facchini, N. M. Maraldi · 2012 · European Journal of Histochemistry
- Nurturing the genomeIgnacio González-Suárez, Susana Gonzalo · 2010 · Nucleus
- An association of Hutchinson–Gilford progeria and malignancyStavit Allon Shalev, Annachiara De Sandre‐Giovannoli, Ayelet Shani‐Adir, Nicolas Lévy · 2007 · American Journal of Medical Genetics Part A
- Nuclear envelope structural defect underlies the main cause of aneuploidy in ovarian carcinogenesisCallinice D. Capo‐chichi, Toni M. Yeasky, Elizabeth R. Smith, Xiang‐Xi Xu · 2016 · BMC Cell Biology
- Aging impairs double-strand break repair by homologous recombination in Drosophila germ cellsLætitia Delabaere, Henry A. Ertl, Dashiell J. Massey, Carolyn M. Hofley, Faraz Sohail, Elisa Jayne Bienenstock, Hans Sebastian, Irene Chiolo, Jeannine R. LaRocque · 2016 · Aging Cell
- Hypoxia-Induced Degenerative Protein Modifications Associated with Aging and Age-Associated DisordersSunil S. Adav, Siu Kwan Sze · 2020 · Aging and Disease
- From old organisms to new molecules: integrative biology and therapeutic targets in accelerated human ageingLynne S. Cox, Richard Faragher · 2007 · Cellular and Molecular Life Sciences
- Genome instability in progeria: when repair gets oldMisteli, Tom, Scaffidi, Paola · 2005 · Nature Medicine
- Current aging research in ChinaRuijuan Sun, Heqi Cao, Xudong Zhu, Junping Liu, Erdan Dong · 2015 · Protein & Cell
- Nesprin-2-dependent ERK1/2 compartmentalisation regulates the DNA damage response in vascular smooth muscle cell ageingDerek T Warren, Tamara Tajsic, Lauren Jade Porter, Rose-Marie Minaisah, Andrew M. Cobb, A Jacob, D Rajgor, Qiuping Zhang, Catherine M. Shanahan · 2015 · Cell Death and Differentiation
- SIRT7 couples light-driven body temperature cues to hepatic circadian phase coherence and gluconeogenesisZuojun Liu, Minxian Qian, Xiaolong Tang, Wenjing Hu, Shimin Sun, Li Guo, Shuju Zhang, Fanbiao Meng, Xinyue Cao, Jie Lena Sun et al. · 2019 · Nature Metabolism
- Lamin A/C recruits ssDNA protective proteins RPA and RAD51 to stalled replication forks to maintain fork stabilitySimona Graziano, Núria Coll-Bonfill, Barbara Teodoro-Castro, Sahiti Kuppa, Jessica Jackson, Elena V. Shashkova, Urvashi Mahajan, Alessandro Vindigni, Edwin Antony, Susana Gonzalo · 2021 · Journal of Biological Chemistry
- The R439C mutation in LMNA causes lamin oligomerization and susceptibility to oxidative stressValerie L. R. M. Verstraeten, Sandrine M. Caputo, Maurice A. M. Van Steensel, Isabelle Duband‐Goulet, Sophie Zinn‐Justin, Miriam A. F. Kamps, Helma J.H. Kuijpers, Cecilia Östlund, Howard J. Worman, Jacob J. Briedé et al. · 2009 · Journal of Cellular and Molecular Medicine
- Lamin post-translational modifications: emerging toggles of nuclear organization and functionLaura A. Murray‐Nerger, Ileana M. Cristea · 2021 · Trends in Biochemical Sciences
- A beginning of the end: new insights into the functional organization of telomeresAshley M. Wood, Kyle Vaughn Laster, Ellen L. Rice, Steven T. Kosak · 2015 · Nucleus
- The nuclear structural protein NuMA is a negative regulator of 53BP1 in DNA double-strand break repairNaike Salvador Moreno, Jing Liu, Karen M. Haas, Laurie L. Parker, Chaitali Chakraborty, Stephen J. Kron, Kurt B. Hodges, Lance David Miller, Carl D. Langefeld, Joseph Paul Robinson et al. · 2019 · Nucleic Acids Research
- Lamin A safeguards the m6A methylase METTL14 nuclear speckle reservoir to prevent cellular senescenceJie Zhang, Ying Ao, Zhen Zhang, Yanzhen Mo, Linyuan Peng, Yue Jiang, Zimei Wang, Baohua Liu · 2020 · Aging Cell
- Accelerated ageing: from mechanism to therapy through animal modelsFernando G. Osorio, Álvaro J. Obaya, Carlos López-Otı́n, José M.P. Freije · 2008 · Transgenic Research
- The Molecular and Cellular Basis of Hutchinson–Gilford Progeria Syndrome and Potential TreatmentsNoelle J. Batista, Sanket G. Desai, Alexis M. Perez, Alexa Finkelstein, Rachel Radigan, Manrose Singh, Aaron Landman, Brian Drittel, Daniella Abramov, Mina Ahsan et al. · 2023 · Genes
- Disruption of PCNA-lamins A/C interactions by prelamin A induces DNA replication fork stallingAndrew M. Cobb, Thomas V. Murray, Derek T Warren, Yiwen Liu, Catherine M. Shanahan · 2016 · Nucleus
- A nuclear lamina‐chromatin‐Ran GTPase axis modulates nuclear import and DNA damage signalingNatalia M. Dworak, Dawid Mąkosa, Mandovi Chatterjee, Kasey Jividen, Chunsong Yang, Chelsi J. Snow, William C. Simke, Isaac G. Johnson, Joshua B. Kelley, Bryce M. Paschal · 2018 · Aging Cell
- Radiation-induced unrepairable DSBs: their role in the late effects of radiation and possible applications to biodosimetryAsao Noda · 2017 · Journal of Radiation Research
- Progeria: Translational insights from cell biologyLeslie B. Gordon, Kan Cao, Francis S. Collins · 2012 · The Journal of Cell Biology
- Protein structural and mechanistic basis of progeroid laminopathiesAgathe Marcelot, Howard J. Worman, Sophie Zinn‐Justin · 2020 · FEBS Journal
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- Skeletal phenotype of mandibuloacral dysplasia associated with mutations in ZMPSTE24Vicki J. Cunningham, Maria Rosaria D’Apice, Norma Licata, Giuseppe Novelli, Tim Cundy · 2010 · Bone
- Inefficient Double-Strand Break Repair in Murine Rod Photoreceptors with Inverted Heterochromatin OrganizationAntonia Frohns, Florian Frohns, Steffen C. Naumann, Paul Gottlob Layer, Markus Löbrich · 2014 · Current Biology
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