A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus–induced lung injury

Kuba, Keiji, Imai, Yumiko, Rao, Shuan, Gao, Hong, Guo, Feng, Guan, Bin, Huan, Yi, Yang, Peng +16 more·2005·Nature Medicine
DOI 10.1038/nm1267

Cited by (1,008)

Items 701–800 of 1,008

  1. Antihypertensive drugs are associated with reduced fatal outcomes and improved clinical characteristics in elderly COVID-19 patients
    Feifei Yan, Fengming Huang, Jun Xu, Penghui Yang, Yuhao Qin, Jingjun Lv, Shaogeng Zhang, Lu Ye, Ming Gong, Zhibo Liu et al. · 2020 · Cell Discovery
  2. Computational Analysis of Targeting SARS-CoV-2, Viral Entry Proteins ACE2 and TMPRSS2, and Interferon Genes by Host MicroRNAs
    Jacob B. Pierce, Viorel Simion, Basak Icli, Daniel Pérez‐Cremades, Henry S. Cheng, Mark W. Feinberg · 2020 · Genes
  3. Vitamin A in resistance to and recovery from infection: relevance to SARS-CoV2
    Charles Bolt Stephensen, Georg Lietz · 2021 · British Journal Of Nutrition
  4. Inhibitors of endosomal acidification suppress SARS-CoV-2 replication and relieve viral pneumonia in hACE2 transgenic mice
    Chao Shang, Xinyu Zhuang, He Zhang, Yiquan Li, Yilong Zhu, Jing Lu, Chenchen Ge, Jianan Cong, Tingyu Li, Mingyao Tian et al. · 2021 · Virology Journal
  5. SARS-CoV-2 Infection of Airway Epithelial Cells
    Gwanghui Ryu, Hyun‐Woo Shin · 2021 · Immune Network
  6. Substituting Angiotensin-(1-7) to Prevent Lung Damage in SARS-CoV-2 Infection?
    Concepción Peiró, Salvador Moncada · 2020 · Circulation
  7. SARS-CoV-2 and cancer: Are they really partners in crime?
    Peter A. van Dam, Manon Thirza Huizing, Gino Mestach, Stazie Dierckxsens, Wiebren A.A. Tjalma, Xuan Bich Trinh, Kostantinos Papadimitriou, Sevilay Altıntaş, Jan Baptist Vermorken, Christof Vulsteke et al. · 2020 · Cancer Treatment Reviews
  8. Altitude and COVID‐19: Friend or foe? A narrative review
    Grégoire Paul Millet, Tadej Debevec, Franck Brocherie, Martin Burtscher, Johannes Burtscher · 2020 · Physiological Reports
  9. Experimental data using candesartan and captopril indicate no double-edged sword effect in COVID-19
    María A. Pedrosa, Rita Valenzuela, Pablo Garrido‐Gil, Carmen M. Labandeira, Gemma Navarro, Rafael Franco, José Luis Labandeira-García, Ana Isabel Rodriguez-Perez · 2021 · Clinical Science
  10. Effects of a DPP-4 Inhibitor and RAS Blockade on Clinical Outcomes of Patients with Diabetes and COVID-19
    Sang Youl Rhee, Jeong-Woo Lee, Hyewon Nam, Dae‐Sung Kyoung, Dong Wook Shin, Dae Jung Kim · 2021 · Diabetes & Metabolism Journal
  11. The Association of Subacute Thyroiditis with COVID-19: a Systematic Review
    Muhammad Aemaz Ur Rehman, Hareem Farooq, Muhammad Mohsin Ali, Muhammad Ebaad Ur Rehman, Qudsia Anwar Dar, Awab Hussain · 2021 · SN Comprehensive Clinical Medicine
  12. SARS-CoV-2 down-regulates ACE2 through lysosomal degradation
    Yi Lu, Qingwei Zhu, Douglas Fox, Carol Gao, Sarah A. Stanley, Kunxin Luo · 2022 · Molecular Biology of the Cell
  13. Priming with SARS CoV S DNA and boosting with SARS CoV S epitopes specific for CD4+ and CD8+ T cells promote cellular immune responses
    J HUANG, Y CAO, Jing Du, Xianzhang Bu, R MA, Chuanbin Wu · 2007 · Vaccine
  14. Myocardial injury is associated with in-hospital mortality of confirmed or suspected COVID-19 in Wuhan, China: A single center retrospective cohort study
    Fan Zhang, Deyan Yang, Jing Li, Peng Gao, Taibo Chen, Zhongwei Cheng, Kangan Cheng, Quan Fang, Wan Pan, Chunfeng Yi et al. · 2020 · medRxiv
  15. Renin-angiotensin-system, a potential pharmacological candidate, in acute respiratory distress syndrome during mechanical ventilation
    Di Wang, Xiaoqing Chai, Costan G. Magnussen, Graeme R. Zosky, Shuhua Shu, Xin Wei, Shanshan Hu · 2019 · Pulmonary Pharmacology & Therapeutics
  16. A rational roadmap for SARS‐CoV‐2/COVID‐19 pharmacotherapeutic research and development: IUPHAR Review 29
    S P H Alexander, Jane F Armstrong, Anthony P. Davenport, Jamie A. Davies, Elena Faccenda, Simon D Harding, Francesca Levi‐Schaffer, Janet J. Maguire, Adam J Pawson, Christopher Southan et al. · 2020 · British Journal of Pharmacology
  17. Potential benefits of combination of Nigella sativa and Zn supplements to treat COVID-19
    Mohammad Tariqur Rahman · 2020 · Journal of Herbal Medicine
  18. Association of vitamin D with the modulation of the disease severity in COVID-19
    Rajab Mardani, Ashkan Alamdary, Seyed Dawood Mousavi Nasab, Reza Gholami, Nayebali Ahmadi, Alireza Gholami · 2020 · Virus Research
  19. Why COVID-19 Transmission Is More Efficient and Aggressive Than Viral Transmission in Previous Coronavirus Epidemics?
    Fatma Elrashdy, Elrashdy M Moustafa Mohamed Redwan, Vladimir Nikolaevich Uversky · 2020 · Biomolecules
  20. Relevance of SARS-CoV-2 related factors ACE2 and TMPRSS2 expressions in gastrointestinal tissue with pathogenesis of digestive symptoms, diabetes-associated mortality, and disease recurrence in COVID-19 patients
    Ashutosh Kumar, Muneeb A. Faiq, Vikas Pareek, Khursheed Raza, Ravi Kant Narayan, Pranav Prasoon, Pavan Kumar, Maheswari Kulandhasamy, Chiman Kumari, Kamla Kant et al. · 2020 · Medical Hypotheses
  21. Can N-3 polyunsaturated fatty acids be considered a potential adjuvant therapy for COVID-19-associated cardiovascular complications?
    Ahmed M. Darwesh, Wesam Bassiouni, Deanna K. Sosnowski, John M. Seubert · 2020 · Pharmacology & Therapeutics
  22. ACE2 mouse models: a toolbox for cardiovascular and pulmonary research
    Hongpeng Jia, Xinping Yue, Eric D. Lazartigues · 2020 · Nature Communications
  23. Rapid design and development of CRISPR-Cas13a targeting SARS-CoV-2 spike protein
    Lin Wang, Junhu Zhou, Qixue Wang, Yunfei Wang, Chunsheng Kang · 2020 · Theranostics
  24. Potential Role of Antioxidant and Anti-Inflammatory Therapies to Prevent Severe SARS-Cov-2 Complications
    Anna Maria Fratta Pasini, Chiara Stranieri, Luciano Cominacini, Chiara Mozzini · 2021 · Antioxidants
  25. The Repurposed ACE2 Inhibitors: SARS-CoV-2 Entry Blockers of Covid-19
    Iqrar Ahmad, Rahul H. Pawara, Sanjay Javerilal Surana, Harun Patel · 2021 · Topics in Current Chemistry
  26. TMPRSS2 Is Essential for SARS-CoV-2 Beta and Omicron Infection
    Kristin Metzdorf, Henning Jacobsen, Marina C. Greweling‐Pils, Markus Hoffmann, Tatjana Lüddecke, Felicitas Miller, Lars Melcher, Amy Madeleine Kempf, Inga Nehlmeier, Dunja Bruder et al. · 2023 · Viruses
  27. Modulation of CD163 Expression by Metalloprotease ADAM17 Regulates Porcine Reproductive and Respiratory Syndrome Virus Entry
    Longjun Guo, Junwei Niu, Haidong Yu, Weihong Gu, Li Ren, Xiaolei Luo, Mingming Huang, Zhi‐Jun Tian, Li Feng, Yue Wang · 2014 · Journal of Virology
  28. HMGB1: A Possible Crucial Therapeutic Target for COVID-19?
    M. Street · 2020 · Hormone Research in Paediatrics
  29. Characteristics, Treatment Outcomes and Role of Hydroxychloroquine among 522 COVID-19 hospitalized patients in Jaipur City: An Epidemio-Clinical Study.
    Sudhir Bhandari, Ajeet Pal Singh, Raman Sharma, Govind Rankawat, Banerjee, S, Vishal Anand Gupta, Amitabh Dube, Shivankan Kakkar · 2022 · PubMed
  30. COVID‐19 and hypertension—evidence and practical management: Guidance from the HOPE Asia Network
    Kazuomi Kario, Yuji Morisawa, Apichard Sukonthasarn, Yuda Turana, Yook Chin Chia, Sungha Park, Tzung‐Dau Wang, Chen‐Huan Chen, Jam Chin Tay, Yan Li et al. · 2020 · Journal of Clinical Hypertension
  31. Clinical Characteristics and Risk Factors of Cardiac Involvement in COVID‐19
    Huayan Xu, Keke Hou, Rong Xu, Zhenlin Li, Hang Fu, Lingyi Wen, Linjun Xie, Hui Liu, Joseph Brindaban Selvanayagam, Na Zhang et al. · 2020 · Journal of the American Heart Association
  32. Severe Acute Respiratory Syndrome Coronavirus 2, COVID-19, and the Renin-Angiotensin System
    Matthew A. Sparks, Andrew Michael South, Andrew D. Badley, Carissa Marrie Baker-Smith, DANIEL C. BATLLE, Biykem Bozkurt, Roberto Cattaneo, Steven D. Crowley, Louis J. Dell’Italia, Andria L. Ford et al. · 2020 · Hypertension
  33. Immunoinflammatory, Thrombohaemostatic, and Cardiovascular Mechanisms in COVID-19
    Selin Gencer, Michael Lacy, Dorothee Atzler, Emiel P. C. van der Vorst, Yvonne Döring, Christian Weber · 2020 · Thrombosis and Haemostasis
  34. Evaluation of electrolyte status of sodium, potassium and magnesium, and fasting blood sugar at the initial admission of individuals with COVID-19 without underlying disease in Golestan Hospital, Kermanshah
    Hosna Sarvazad, S.H. Cahngaripour, Narges Eskandari Roozbahani, Babak Izadi · 2020 · New Microbes and New Infections
  35. Neurotropic Viruses, Astrocytes, and COVID-19
    Petra Tavčar Verdev, Maja Potokar, Marko Kolenc, Miša Korva, Tatjana Avšič‐Županc, Robert Zorec, Jernej Jorgačevski · 2021 · Frontiers in Cellular Neuroscience
  36. Effects of SARS-CoV-2 on Cardiovascular System: The Dual Role of Angiotensin-Converting Enzyme 2 (ACE2) as the Virus Receptor and Homeostasis Regulator-Review
    Aneta Aleksova, Giulia Gagno, Gianfranco Sinagra, Antonio Paolo Beltrami, Milijana Janjusevic, Giuseppe Ippolito, Alimuddin I. Zumla, Alessandra Lucia Fluca, Federico Ferro · 2021 · International Journal of Molecular Sciences
  37. ACE2 is the critical in vivo receptor for SARS-CoV-2 in a novel COVID-19 mouse model with TNF- and IFNγ-driven immunopathology
    Riem Gawish, Philipp M. Starkl, Lisabeth Pimenov, Anastasiya Hladik, Karin Lakovits, Felicitas Oberndorfer, Shane J. Cronin, Anna Ohradanova‐Repic, Gerald Wirnsberger, Benedikt Agerer et al. · 2022 · eLife
  38. Effect of Angiotensin-Converting Enzyme Inhibitor and Angiotensin Receptor Blocker Initiation on Organ Support–Free Days in Patients Hospitalized With COVID-19
    Simin Aysel Florescu, Dragos Stanciu, Mihaela Florentina Zaharia, Alma Gabriela Kosa, Daniel Romeo Codreanu, Komal Fareed, Aneela Kidwai, Callum T. Kaye, Amanda Coutts, Lynn MacKay et al. · 2023 · JAMA
  39. The Role of Adaptogens in Prophylaxis and Treatment of Viral Respiratory Infections
    Alexander George Panossian, Thomas Brendler · 2020 · Pharmaceuticals
  40. Role of angiotensin-converting enzyme (ACE) and ACE2 in a rat model of smoke inhalation induced acute respiratory distress syndrome
    Zhao Yilin, Nan Yandong, Jin F · 2015 · Burns
  41. Participation of both Host and Virus Factors in Induction of Severe Acute Respiratory Syndrome (SARS) in F344 Rats Infected with SARS Coronavirus
    Noriyo Nagata, Naoko Iwata, Hideki Hasegawa, Shuetsu Fukushi, Masaru Yokoyama, Ayako Harashima, Yuko Sato, Masayuki Saijo, Shigeru Morikawa, Tetsutaro Sata · 2006 · Journal of Virology
  42. Free SARS-CoV-2 Spike Protein S1 Particles May Play a Role in the Pathogenesis of COVID-19 Infection
    Andrey V. Letarov, Vladislav V. Babenko, Eugene E. Kulikov · 2020 · Biochemistry (Moscow)
  43. SARS-CoV-2 and Other Respiratory Viruses: What Does Oxidative Stress Have to Do with It?
    Iara Grigoletto Fernandes, Cyro Alves de Brito, Vitor Manoel Silva dos Reis, Maria Notomi Sato, Nátalli Zanete Pereira · 2020 · Oxidative Medicine and Cellular Longevity
  44. Disease-associated dysbiosis and potential therapeutic role of Akkermansia muciniphila, a mucus degrading bacteria of gut microbiome
    Vidushi Aggarwal, Sushant Sunder, Smita Rastogi Verma · 2022 · Folia Microbiologica
  45. Nicotianamine is a novel angiotensin-converting enzyme 2 inhibitor in soybean
    Saori Takahashi, Taku Yoshiya, Kumiko Yoshizawa‐Kumagaye, Toshihiro Sugiyama · 2015 · Biomedical Research
  46. Potential Benefits and Harms of Novel Antidiabetic Drugs During COVID-19 Crisis
    Maria Mirabelli, EUSEBIO D. CHIEFARI, Luigi Puccio, DANIELA PATRIZIA FOTI, Antonio Brunetti · 2020 · International Journal of Environmental Research and Public Health
  47. B38-CAP is a bacteria-derived ACE2-like enzyme that suppresses hypertension and cardiac dysfunction
    Takafumi Minato, Satoru Nirasawa, Teruki Sato, Tomokazu Yamaguchi, Midori Hoshizaki, Tadakatsu Inagaki, Kazuhiko Nakahara, Tadashi Yoshihashi, Ryo Ozawa, Saki Yokota et al. · 2020 · Nature Communications
  48. ACE2, Metformin, and COVID-19
    Atul Malhotra, Mark Hepokoski, Karen Clare McCowen, John Y-J Shyy · 2020 · iScience
  49. The interplay between emerging human coronavirus infections and autophagy
    Zhenyu Zhao, Kefeng Lu, Binli Mao, Shi Liu, Mirko Trilling, Ailong Huang, Mengji Lu, Yong Lin · 2021 · Emerging Microbes & Infections
  50. PDE4 inhibition as a therapeutic strategy for improvement of pulmonary dysfunctions in Covid-19 and cigarette smoking
    Claire Lugnier, Hayder Mutter Al-Kuraishy, Éric Rousseau · 2021 · Biochemical Pharmacology
  51. Selinexor, a novel selective inhibitor of nuclear export, reduces SARS-CoV-2 infection and protects the respiratory system in vivo
    Trinayan Kashyap, Jackelyn Murray, Christopher James Walker, Hua Chang, Sharon Tamir, Bing Hou, Sharon Shacham, Michael G. Kauffman, Ralph A. Tripp, Yosef Landesman · 2021 · Antiviral Research
  52. Potent prophylactic and therapeutic efficacy of recombinant human ACE2-Fc against SARS-CoV-2 infection in vivo
    Zhaoyong Zhang, Eric Zeng, Lu Zhang, Weiming Wang, Yingkang Jin, Jiye Sun, Shuxiang Huang, Wenguang Yin, Jun Dai, Zhen Zhuang et al. · 2021 · Cell Discovery
  53. Classical Renin‐Angiotensin System in Kidney Physiology
    Matthew A. Sparks, Steven D. Crowley, Susan B. Gurley, Maria Mirotsou, Thomas M. Coffman · 2014 · Comprehensive physiology
  54. Iterative community-driven development of a SARS-CoV-2 tissue simulator
    Michael Getz, Yafei Wang, Gary C. An, Maansi Asthana, Andrew Becker, Chase Cockrell, Nicholson T. Collier, Morgan Craig, Courtney L. Davis, James R. Faeder et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  55. Marked Up-Regulation of ACE2 in Hearts of Patients With Obstructive Hypertrophic Cardiomyopathy: Implications for SARS-CoV-2–Mediated COVID-19
    Johan Martijn Bos, Virginia B. Hebl, Ann L. Oberg, Zhifu Sun, Daniel S. Herman, Polakit Teekakirikul, Jonathan G. Seidman, Christine E. Seidman, Cristobal G. dos Remedios, Joseph John Maleszewski et al. · 2020 · Mayo Clinic Proceedings
  56. Pain: A potential new label of COVID-19
    Si Su, Huan Cui, Tao Wang, Xinhua Shen, Chao Ma · 2020 · Brain Behavior and Immunity
  57. Neonatal Coronavirus 2019 (COVID-19) Infection: A Case Report and Review of Literature
    Vikramaditya Dumpa, Ranjith Kamity, Alexandra Vinci, Estela Noyola, Asif Noor · 2020 · Cureus
  58. Is the use of ACE inb/ARBs associated with higher in-hospital mortality in Covid-19 pneumonia patients?
    Murat Selçuk, Tufan Çınar, Muhammed Keskin, Vedat Çiçek, Şahhan Kılıç, Behruz Kenan, Selami Doğan, Süha Asal, Nuran Günay, Ersin Yıldırım et al. · 2020 · Clinical and Experimental Hypertension
  59. A historical perspective on ACE2 in the COVID-19 era
    Vivek Bhalla, Catherine A. Blish, Andrew Michael South · 2020 · Journal of Human Hypertension
  60. The mechanism of multiple organ dysfunction syndrome in patients with COVID‐19
    Wenbin Zhao, Hanmeng Li, Jianghua Li, Bin Xu, Jian Xu · 2022 · Journal of Medical Virology
  61. Apolipoprotein E and viral infection: Risks and Mechanisms
    Feng Chen, Qiongwei Ke, Wenyan Wei, Lili Cui, Yan Wang · 2023 · Molecular Therapy — Nucleic Acids
  62. TLR3 Regulated Poly I:C-Induced Neutrophil Extracellular Traps and Acute Lung Injury Partly Through p38 MAP Kinase
    Tingting Gan, Yonglin Yang, Fan Hu, Xichen Chen, Jiawei Zhou, Yan Li, Ying Xu, Huijuan Wang, Yu Chen, Mingshun Zhang · 2018 · Frontiers in Microbiology
  63. SARS-CoV-2, More than a Respiratory Virus: Its Potential Role in Neuropathogenesis
    Chitra Mohinder Singh Singal, Paritosh Jaiswal, Pankaj Seth · 2020 · ACS Chemical Neuroscience
  64. Cellular and Humoral Immune Responses in Covid-19 and Immunotherapeutic Approaches
    Amal Hasan, Ebaa Al‐Ozairi, Zahraa Albaqsumi, Rasheed Ahmad, Fahd Al‐Mulla · 2021 · ImmunoTargets and Therapy
  65. Nanotechnology as a Shield against COVID-19: Current Advancement and Limitations
    Mahendra Rai, Shital Bonde, Alka Yadav, Arpita Bhowmik, Sanjay Rathod, Pramod U. Ingle, Aniket Gade · 2021 · Viruses
  66. Resveratrol supplementation reduces ACE2 expression in human adipose tissue
    Marlies de Ligt, Matthijs K. C. Hesselink, Johanna A. Jörgensen, Nicole Hoebers, Ellen E. Blaak, Gijs H. Goossens · 2021 · Adipocyte
  67. The dual role of toll-like receptors in COVID-19: Balancing protective immunity and immunopathogenesis
    Payam Behzadi, Deepak Chandran, Chiranjib Chakraborty, Manojit Bhattacharya, Guttula Saikumar, Kuldeep Dhama, Ankita Chakraborty, Suprabhat Mukherjee, Meysam Sarshar · 2024 · International Journal of Biological Macromolecules
  68. COVID-19 pandemic outbreak: the Brazilian reality from the first case to the collapse of health services
    Cristiane Moutinho Lagos de Melo, Guilherme Antonio de Souza Silva, Alanne Rayssa da Silva Melo, Antônio Carlos de Freitas · 2020 · Anais da Academia Brasileira de Ciências
  69. Altered COVID-19 receptor ACE2 expression in a higher risk group for cerebrovascular disease and ischemic stroke
    Ji‐Young Choi, Hye‐Kyung Lee, Jung Hyun Park, Sun‐Jung Cho, Munjin Kwon, Chulman Jo, Young Ho Koh · 2020 · Biochemical and Biophysical Research Communications
  70. Outbreak of SARS-CoV2: Pathogenesis of infection and cardiovascular involvement
    Hamideh Amirfakhryan, Fatemeh Safari · 2020 · Hellenic Journal of Cardiology
  71. Involvement of cardiovascular system as the critical point in coronavirus disease 2019 (COVID-19) prognosis and recovery
    Charalampos Lazaridis, Nikolaos I. Vlachogiannis, Constantinos Bakogiannis, Ioakim Spyridopoulos, Kimon S. Stamatelopoulos, Ioannis Kanakakis, Vassilios Pericles Vassilikos, Konstantinos Stellos · 2020 · Hellenic Journal of Cardiology
  72. Impaired Breakdown of Bradykinin and Its Metabolites as a Possible Cause for Pulmonary Edema in COVID-19 Infection
    Steven de Maat, Quirijn de Mast, A.H. Jan Danser, Frank L. van de Veerdonk, Coen Maas · 2020 · Seminars in Thrombosis and Hemostasis
  73. Energetics and IC50 based epitope screening in SARS CoV-2 (COVID 19) spike protein by immunoinformatic analysis implicating for a suitable vaccine development
    Amrita Banerjee, Dipannita Santra, Smarajit Maiti · 2020 · Journal of Translational Medicine
  74. Spironolactone may provide protection from SARS-CoV-2: Targeting androgens, angiotensin converting enzyme 2 (ACE2), and renin-angiotensin-aldosterone system (RAAS)
    Flavio Cadegiani, Andy Goren, Carlos Gustavo Wambier · 2020 · Medical Hypotheses
  75. Update of the current knowledge on genetics, evolution, immunopathogenesis, and transmission for coronavirus disease 19 (COVID-19)
    Kalthoum Tizaoui, Inès Zidi, Keum Hwa Lee, Ramy Abou Ghayda, Sung Hwi Hong, Han Li, Lee Smith, Ai Koyanagi, Louis Jacob, Andreas Kronbichler et al. · 2020 · International Journal of Biological Sciences
  76. ACE2-like carboxypeptidase B38-CAP protects from SARS-CoV-2-induced lung injury
    Tomokazu Yamaguchi, Midori Hoshizaki, Takafumi Minato, Satoru Nirasawa, Masamitsu N. Asaka, Mayumi Niiyama, Masaki Imai, Akihiko Uda, Jasper Fuk‐Woo Chan, Saori Takahashi et al. · 2021 · Nature Communications
  77. COVID-19: An overview and a clinical update
    Arunkumar Krishnan, James P. Hamilton, Saleh A. Alqahtani, Tinsay A. Woreta · 2020 · World Journal of Clinical Cases
  78. Transcriptome of nasopharyngeal samples from COVID-19 patients and a comparative analysis with other SARS-CoV-2 infection models reveal disparate host responses against SARS-CoV-2
    Abul Bashar Mir Md. Khademul Islam, Md. Abdullah‐Al‐Kamran Khan, Rasel Ahmed, Md. Sabbir Hossain, Shah Md Tamim Kabir, Md. Shahidul Islam, AMAM Zonaed Siddiki · 2021 · Journal of Translational Medicine
  79. Simvastatin Downregulates the SARS-CoV-2-Induced Inflammatory Response and Impairs Viral Infection Through Disruption of Lipid Rafts
    Lívia Teixeira, Jairo Ramos Temerozo, Filipe Santos Pereira-Dutra, André Costa Ferreira, Mayara Mattos, Barbara Simonson Gonçalves, Carolina Q. Sacramento, Lohanna Palhinha, Tamires Cunha‐Fernandes, Suelen da Silva Gomes Dias et al. · 2022 · Frontiers in Immunology
  80. Platelet activation by SARS-CoV-2 implicates the release of active tissue factor by infected cells
    Florian Puhm, Isabelle Allaeys, Émile Lacasse, Isabelle Dubuc, Yannick Galipeau, Younes Zaid, Loubna Khalki, Clémence Belleannée, Yves Durocher, Alain R. Brisson et al. · 2022 · Blood Advances
  81. Toxicity and therapeutic applications of citrus essential oils (CEOs): a review
    Augustine Suurinobah Brah, Francis Ackah Armah, Collins Obuah, Samuel Addo Akwetey, Christian K. Adokoh · 2023 · International Journal of Food Properties
  82. Progress in Anti-SARS Coronavirus Chemistry, Biology and Chemotherapy
    Arun Kumar Ghosh, Kai Xi, Michael E. Johnson, Susan C. Baker, Andrew D. Mesecar · 2006 · Annual reports in medicinal chemistry
  83. SARS Coronavirus and Lung Fibrosis
    Wei Zuo, Xingang Zhao, Ye‐Guang Chen · 2009 · Springer eBooks
  84. Old Drugs for a New Virus: Repurposed Approaches for Combating COVID-19
    Sirle Saul, Shirit Einav · 2020 · ACS Infectious Diseases
  85. Advances in the possible treatment of COVID-19: A review.
    Pankaj Chibber, Syed Assim Haq, Irfan Ahmed, Nusrit Iqbal Andrabi, Gurdarshan Singh · 2020 · European Journal of Pharmacology
  86. Nanomedicine strategies to target coronavirus
    Marcel Alexander Heinrich, B. E. E. Martina, Jai Prakash · 2020 · Nano Today
  87. Endothelialitis plays a central role in the pathophysiology of severe COVID-19 and its cardiovascular complications
    Christiaan J. Vrints, Konstantin Alexander Krychtiuk, Emeline M. Van Craenenbroeck, Vincent F. M. Segers, Susanna Price, Hein Heidbüchel · 2020 · Acta cardiologica. Supplementum
  88. Role of arachidonic cascade in COVID-19 infection: A review
    Md. Abdur Rahman Ripon, Dipty Rani Bhowmik, Mohammad Tohidul Amin, Mohammad Salim Hossain · 2021 · Prostaglandins & Other Lipid Mediators
  89. ACE2 Down-Regulation May Act as a Transient Molecular Disease Causing RAAS Dysregulation and Tissue Damage in the Microcirculatory Environment Among COVID-19 Patients
    Simone Gusmão Ramos, Bruna Amanda da Cruz Rattis, Giulia Ottaviani, MD, PhD, Mara Rúbia Nunes Celes, Eliane Pedra Dias · 2021 · American Journal Of Pathology
  90. Lung Cancer Models Reveal Severe Acute Respiratory Syndrome Coronavirus 2–Induced Epithelial-to-Mesenchymal Transition Contributes to Coronavirus Disease 2019 Pathophysiology
    Catherine Allison Stewart, Carl Michael Gay, Kavya Ramkumar, Kasey R. Cargill, Robert J. Cardnell, Monique B. Nilsson, Simon Heeke, Elizabeth M. Park, Samrat T. Kundu, Lixia Diao et al. · 2021 · Journal of Thoracic Oncology
  91. SNPs of ACE1 (rs4343) and ACE2 (rs2285666) genes are linked to SARS-CoV-2 infection but not with the severity of disease
    Nahid Alimoradi, Moein Sharqi, Dena Firouzabadi, Mohammad Moein Sadeghi, Seyed Mohammad Iman Moezzi, Negar Firouzabadi · 2022 · Virology Journal
  92. Phosphatidylinositol 4-Kinase IIIβ Is Required for Severe Acute Respiratory Syndrome Coronavirus Spike-mediated Cell Entry
    Ning Yang, Ping Ma, Jianshe Lang, Yanli Zhang, Jiejie Deng, Xiangwu Ju, Gongyi Zhang, Chengyu Jiang · 2012 · Journal of Biological Chemistry
  93. Drug Targets in Severe Acute Respiratory Syndrome (SARS) Virus and other Coronavirus Infections
    Tommy Richard Sun-wing Tong · 2009 · Infectious Disorders - Drug Targets
  94. The Nrf2 Activator (DMF) and Covid-19: Is there a Possible Role?
    Saif Hassan, Mahmood Jasem Jawad, Salam Waheed Ahjel, Ram Pyare Singh, Jaipaul Singh, Samir M. Awad, Najah Hadi · 2020 · Medical Archives
  95. Angiotensin converting enzyme: A review on expression profile and its association with human disorders with special focus on SARS-CoV-2 infection
    Soudeh Ghafouri‐Fard, Rezvan Noroozi, Mir Davood Omrani, Wojciech Branicki, Ewelina Pośpiech, Arezou Sayad, Krzysztof Pyrć, Paweł P. Łabaj, Reza Vafaee, Mohammad Naser Taheri et al. · 2020 · Vascular Pharmacology
  96. Use of inhibitors of the renin‐angiotensin system in hypertensive patients and COVID‐19 severity: A systematic review and meta‐analysis
    Jessica Barochiner, Rocío Martínez · 2020 · Journal of Clinical Pharmacy and Therapeutics
  97. Obesity, Diabetes and COVID-19: An Infectious Disease Spreading From the East Collides With the Consequences of an Unhealthy Western Lifestyle
    Jeff M.P. Holly, Kalina M. Biernacka, Nick A. Maskell, Claire M. Perks · 2020 · Frontiers in Endocrinology
  98. Computational biophysical characterization of the SARS-CoV-2 spike protein binding with the ACE2 receptor and implications for infectivity
    Ratul Chowdhury, Veda Sheersh Boorla, Costas D. Maranas · 2020 · Computational and Structural Biotechnology Journal
  99. An Assessment on Impact of COVID-19 Infection in a Gender Specific Manner
    Himanshu Agrawal, Neeladrisingha Das, Sandip Nathani, Sarama Saha, Surendra Kumar Saini, Sham S. Kakar, Partha Roy · 2020 · Stem Cell Reviews and Reports
  100. Emerging Mechanisms of Pulmonary Vasoconstriction in SARS-CoV-2-Induced Acute Respiratory Distress Syndrome (ARDS) and Potential Therapeutic Targets
    Harry Karmouty‐Quintana, Rajarajan A. Thandavarayan, Steven P. Keller, Sandeep Sahay, Lavannya M. Pandit, Bindu H. Akkanti · 2020 · International Journal of Molecular Sciences