Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction

Trautmann, Lydie, Janbazian, Loury, Chomont, Nicolas, Said, Elias A, Gimmig, Sylvain, Bessette, Benoit, Boulassel, Mohamed-Rachid, Delwart, Eric +5 more·2006·Nature Medicine
DOI 10.1038/nm1482

Cited by (1,001)

Items 301–400 of 1,001

  1. Mechanisms of CD8 + T cell‐mediated suppression of HIV/SIV replication
    Julia Bergild McBrien, Nitasha Kumar, Guido Silvestri · 2018 · European Journal of Immunology
  2. Delayed differentiation of potent effector CD8 + T cells reducing viremia and reservoir seeding in acute HIV infection
    Hiroshi Takata, Supranee Buranapraditkun, Cari F. Kessing, James L. K. Fletcher, Roshell Muir, Virginie Tardif, Pearline Cartwright, Claire Vandergeeten, Wendy Bakeman, Carmen N. Nichols et al. · 2017 · Science Translational Medicine
  3. Stem, Effector, and Hybrid States of Memory CD8+ T Cells
    Enrico Lugli, Giovanni Galletti, Shannon Kathryn Boi, Ben Youngblood · 2019 · Trends in Immunology
  4. Assessment of the Feasibility and Safety of Durvalumab for Treatment of Solid Tumors in Patients With HIV-1 Infection
    Maria Gonzalez-Cao, Teresa Morán, Judith Dalmau, Javier Garcia-Corbacho, Jillian Wilhelmina Paulina Bracht, Reyes Bernabé, Óscar Juan, Javier de Castro, Remei Blanco, Ana Drozdowskyj et al. · 2020 · JAMA Oncology
  5. Dendritic cell dysregulation during HIV ‐1 infection
    Elizabeth Miller, Nina Bhardwaj · 2013 · Immunological Reviews
  6. Upregulation of PD-L1 on monocytes and dendritic cells by HIV-1 derived TLR ligands
    Angela Meier, Aranya Bagchi, Harlyn K. Sidhu, Galit Alter, Todd J. Suscovich, Daniel G. Kavanagh, Hendrik Streeck, Mark A. Brockman, Sylvie Le Gall, Judith Hellman et al. · 2008 · AIDS
  7. Premature Terminal Exhaustion of Friend Virus-Specific Effector CD8+ T Cells by Rapid Induction of Multiple Inhibitory Receptors
    Shiki Takamura, Sachiyo Tsuji-Kawahara, Hideo Yagita∥, Hisaya Akiba, Mayumi Sakamoto, Tomomi Chikaishi, Maiko Kato, Masaaki Miyazawa · 2010 · The Journal of Immunology
  8. Is HIV infection a TNF receptor signalling-driven disease?
    Georges Herbein, Kashif Aziz Khan · 2008 · Trends in Immunology
  9. CTLA-4 and PD-1 dual blockade induces SIV reactivation without control of rebound after antiretroviral therapy interruption
    Justin L. Harper, Shari N. Gordon, Chi Ngai Chan, Hong Wang, Emily Lindemuth, Cristin M. Galardi, Shane D. Falcinelli, Samuel L M Raines, Jenna Read, Kevin Nguyen et al. · 2020 · Nature Medicine
  10. Replicative fitness of transmitted HIV-1 drives acute immune activation, proviral load in memory CD4 + T cells, and disease progression
    Daniel T. Claiborne, Jessica L. Prince, Eileen P. Scully, Gladys N. Macharia, Luca Micci, Benton Lawson, Jakub T. Kopycinski, Martin J. Deymier, Thomas H. Vanderford, Krystelle Nganou‐Makamdop et al. · 2015 · Proceedings of the National Academy of Sciences
  11. Interferon-sensitive response element (ISRE) is mainly responsible for IFN-α-induced upregulation of programmed death-1 (PD-1) in macrophages
    Hae-Yun Cho, Soo-Woon Lee, Su‐Kil Seo, Il‐Whan Choi, Inhak Choi, Soo-Woong Lee · 2008 · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
  12. Enhanced Anti-HIV Functional Activity Associated with Gag-Specific CD8 T-Cell Responses
    Boris Dominik Jülg, Katie L. Williams, S. Reddy, Karen Suzanne Bishop, Y. Qi, Mary N Carrington, Philip Goulder, Thumbi Ndung’u, Bruce D. Walker · 2010 · Journal of Virology
  13. Effect of polysaccharide from cultured Cordyceps sinensis on immune function and anti-oxidation activity of mice exposed to 60Co
    Jiali Zhang, Yongchao Yu, Zhaofeng Zhang, Ye Ding, Xiaoqian Dai, Yong Li · 2011 · International Immunopharmacology
  14. HIV-Specific IL-21 Producing CD4+ T Cells Are Induced in Acute and Chronic Progressive HIV Infection and Are Associated with Relative Viral Control
    Feng Yun Yue, Calvin C. Lo, Ali Sakhdari, Erika Yue Lee, Colin M Kovacs, Erika Benko, Jun Liu, Haihan Song, Richard Brad Jones, Prameet M. Sheth et al. · 2010 · The Journal of Immunology
  15. Impaired Hepatitis C Virus (HCV)-Specific Effector CD8 + T Cells Undergo Massive Apoptosis in the Peripheral Blood during Acute HCV Infection and in the Liver during the Chronic Phase of Infection
    Henry Radziewicz, Chris Ibegbu, Huiming Hon, Melissa K. Osborn, Kamil M. Obideen, Mohammad A. Wehbi, Gordon James Freeman, Jeffrey L. Lennox, Kimberly Workowski, Holly L. Hanson et al. · 2008 · Journal of Virology
  16. Tumor-associated Tregs obstruct antitumor immunity by promoting T cell dysfunction and restricting clonal diversity in tumor-infiltrating CD8+ T cells
    David R. Noyes, Arup Kumar Bag, Saheed Oluwasina Oseni, Jon Semidey-Hurtado, Ling Cen, Amod A. Sarnaik, Vernon K. Sondak, Dennis O. Adeegbe · 2022 · Journal for ImmunoTherapy of Cancer
  17. Severe functional impairment and elevated PD‐1 expression in CD1d‐restricted NKT cells retained during chronic HIV‐1 infection
    Markus Moll, Carlotta Kuylenstierna, Veronica D. Gonzalez, Sofia K. Andersson, Lidija Bosnjak, Anders B. Sönnerborg, Máire F. Quigley, Johan K. Sandberg · 2009 · European Journal of Immunology
  18. Antigen-Independent Induction of Tim-3 Expression on Human T Cells by the Common γ-Chain Cytokines IL-2, IL-7, IL-15, and IL-21 Is Associated with Proliferation and Is Dependent on the Phosphoinositide 3-Kinase Pathway
    Shariq Mujib, Richard Brad Jones, Calvin C. Lo, Nasra Aidarus, Kiera Clayton, Ali Sakhdari, Erika Benko, Colin M Kovacs, Mario Ostrowski · 2012 · The Journal of Immunology
  19. Success and failure of the cellular immune response against HIV-1
    Stephen A. Migueles, Mark Connors · 2015 · Nature Immunology
  20. PD-1, gender, and autoimmunity
    Ravi K. Dinesh, Bevra Hannahs Hahn, Ram Pyare Singh · 2010 · Autoimmunity Reviews
  21. HIV: Inflammation and Bone
    Ighovwerha Ofotokun, Emily B. McIntosh, M. Neale Weitzmann · 2011 · Current HIV/AIDS Reports
  22. An atlas of immune cell exhaustion in HIV-infected individuals revealed by single-cell transcriptomics
    Shaobo Wang, Qiong Zhang, Hui Hui, Kriti Agrawal, Maile Karris, Tariq M. Rana · 2020 · Emerging Microbes & Infections
  23. 4-1BB Signaling Synergizes with Programmed Death Ligand 1 Blockade To Augment CD8 T Cell Responses during Chronic Viral Infection
    Vaiva Vezys, Pablo Penaloza‐MacMaster, Daniel L. Barber, Sang‐Jun Ha, Bogumila T. Konieczny, Gordon James Freeman, Robert S. Mittler, Rafi Ahmed · 2011 · The Journal of Immunology
  24. Long-Term Persistence of Exhausted CD8 T Cells in Chronic Infection Is Regulated by MicroRNA-155
    Erietta Stelekati, Zeyu Chen, Sasikanth Manne, Makoto Kurachi, Mohammed-Alkhatim Ali, Keith Lewy, Zhangying Cai, Kito Nzingha, Laura M. McLane, Jennifer L. Hope et al. · 2018 · Cell Reports
  25. Activating PIK3CD mutations impair human cytotoxic lymphocyte differentiation and function and EBV immunity
    Emily S.J. Edwards, Julia Bier, Theresa S. Cole, Melanie Wong, Peter S. Hsu, Lucinda J. Berglund, Kaan Boztuǧ, Anthony Lau, Emma Gostick D, David A. Price et al. · 2018 · Journal of Allergy and Clinical Immunology
  26. The PD-1/PD-L1 pathway: biological background and clinical relevance of an emerging treatment target in immunotherapy
    Simone E. Muenst, Savas Deniz Soysal, Alexandar Tzankov, Sylvia Hoeller · 2014 · Expert Opinion on Therapeutic Targets
  27. CD8+ T-Cell Response to HIV Infection in the Era of Antiretroviral Therapy
    Federico Perdomo-Celis, Natalia A. Taborda, Marı́a Teresa Rugeles · 2019 · Frontiers in Immunology
  28. Telomerase in T Lymphocytes: Use It and Lose It?
    Akbar, Arne N, Vukmanovic-Stejic, Milica · 2007 · The Journal of Immunology
  29. T-cell exhaustion in tuberculosis: pitfalls and prospects
    Nargis Khan, Aurobind Vidyarthi, Mohammed Amir, Khurram Mushtaq, Javed Naim Agrewala · 2016 · Critical Reviews in Microbiology
  30. Detrimental Contribution of the Immuno-Inhibitor B7-H1 to Rabies Virus Encephalitis
    Monique Lafon, Françoise Mégret, Sven Guenther Meuth, Ole J. Simon, Myriam Lucía Velandia-Romero, Mireille Lafage, Lieping Chen, Lena Alexopoulou, Richard Anthony Flavell, Christophe J. N. Prehaud et al. · 2008 · The Journal of Immunology
  31. BTLA expression contributes to septic morbidity and mortality by inducing innate inflammatory cell dysfunction
    Nicholas J. Shubin, Chun S. Chung, Daithi S. Heffernan, Lydea R. Irwin, Sean F. Monaghan, Alfred Ayala · 2012 · Journal of Leukocyte Biology
  32. Identification of PD-1 as a Unique Marker for Failing Immune Reconstitution in HIV-1–Infected Patients on Treatment
    Katharina Grabmeier‐Pfistershammer, Peter Steinberger, Armin Rieger, Judith Maria Leitner, Norbert Kohrgruber · 2010 · JAIDS Journal of Acquired Immune Deficiency Syndromes
  33. Relationship between Functional Profile of HIV-1 Specific CD8 T Cells and Epitope Variability with the Selection of Escape Mutants in Acute HIV-1 Infection
    Guido Ferrari, Bette Korber, Nilu P Goonetilleke, Michael K. P. Liu, Emma L. Turnbull, Jesus F. Salazar-Gonzalez, Natalie R. Hawkins, Steve G Self, Sydeaka Watson, Michael R. Betts et al. · 2011 · PLoS Pathogens
  34. Demethylation of the PD-1 Promoter Is Imprinted during the Effector Phase of CD8 T Cell Exhaustion
    Eunseon Ahn, Ben Youngblood, Junghwa Lee, Judong Lee, Surojit Sarkar, Rafi Ahmed · 2016 · Journal of Virology
  35. How chronic viral infections impact on antigen‐specific T‐cell responses
    Helge Frebel, Kirsten Richter, Annette Oxenius · 2010 · European Journal of Immunology
  36. Positive and Negative Regulation of Cellular Immune Responses in Physiologic Conditions and Diseases
    Selena Viganó, Matthieu Perreau, Giuseppe Pantaleo, Alexandre Harari · 2012 · Clinical and Developmental Immunology
  37. PD-1/PD-L1 pathway and T-cell exhaustion in chronic hepatitis virus infection
    T. Watanabe, Antonio Bertoletti, Anthony Tanoto Tan · 2010 · Journal of Viral Hepatitis
  38. PD-1 Blockade in Chronically HIV-1-Infected Humanized Mice Suppresses Viral Loads
    Edward Seung, Timothy E. Dudek, Todd M. Allen, Gordon James Freeman, Andrew David Luster, Andrew Martin Tager · 2013 · PLoS ONE
  39. The multifaceted nature of HIV latency
    Caroline Dufour, Pierre Gantner, Rémi Fromentin, Nicolas Chomont · 2020 · Journal of Clinical Investigation
  40. Tim-3-Expressing CD4+ and CD8+ T Cells in Human Tuberculosis (TB) Exhibit Polarized Effector Memory Phenotypes and Stronger Anti-TB Effector Functions
    Yueqin Qiu, Jianbo Chen, Hongying Liao, Yan Zhang, Hua Wang, Shaoyuan Li, Yanfen Luo, Danyun Fang, Guobao Li, Boping Zhou et al. · 2012 · PLoS Pathogens
  41. Tim-3 Negatively Regulates Cytotoxicity in Exhausted CD8+ T Cells in HIV Infection
    Ali Sakhdari, Shariq Mujib, Bahareh Vali, Feng Yun Yue, Sonya A. MacParland, Kiera Clayton, Richard Brad Jones, Jun Liu, Erika Yue Lee, Erika Benko et al. · 2012 · PLoS ONE
  42. HIV Pathogenesis: The Host
    Andrew A. Lackner, M. M. Lederman, Benigno A. Rodriguez · 2012 · Cold Spring Harbor Perspectives in Medicine
  43. TCF-1 regulates HIV-specific CD8+ T cell expansion capacity
    Rachel Lena Rutishauser, Christian Deo T. Deguit, Joseph B Hiatt, Franziska Blaeschke, Theodore L. Roth, Lynn Wang, Kyle A. Raymond, Carly E. Starke, Joseph C. Mudd, Wenxuan Chen et al. · 2020 · JCI Insight
  44. Programmed Death-1 Is a Marker for Abnormal Distribution of Naive/Memory T Cell Subsets in HIV-1 Infection
    Gaëlle Breton, Nicolas Chomont, Hiroshi Takata, Rémi Fromentin, Jeffrey D. Ahlers, Abdelali Filali-Mouhim, Catherine Riou, Mohamed‐Rachid Boulassel, Jean‐Pierre Routy, Bader Yassine‐Diab et al. · 2013 · The Journal of Immunology
  45. Immunological approaches to HIV cure
    Adam R. Ward, Talia M. Mota, Richard Brad Jones · 2020 · Seminars in Immunology
  46. The contextual role of TNFR family members in CD 8+ T‐cell control of viral infections
    Michael E. Wortzman, Derek Clouthier, Ann J. McPherson, Gloria Hoi Ying Lin, Tania H. Watts · 2013 · Immunological Reviews
  47. Antiviral NK cell responses in HIV infection: I. NK cell receptor genes as determinants of HIV resistance and progression to AIDS
    Alexandre Iannello, Olfa Débbeche, Suzanne Samarani, Ali Ahmad · 2008 · Journal of Leukocyte Biology
  48. PD-1/PD-L1 Based Combinational Cancer Therapy: Icing on the Cake
    Jianye Zhang, Yanyan Yan, Jiajun Li, Rameshwar Adhikari, Liwu Fu · 2020 · Frontiers in Pharmacology
  49. T Cells from Programmed Death-1 Deficient Mice Respond Poorly to Mycobacterium tuberculosis Infection
    Sultan Tousif, Yogesh Singh, Durbaka V. R. Prasad, Pawan Sharma, Luc Van Kaer, Gobardhan Das · 2011 · PLoS ONE
  50. Augmented expression of programmed death‐1 in both neoplastic and non‐neoplastic CD4+ T‐cells in adult T‐cell leukemia/lymphoma
    Takatoshi Shimauchi, Kenji Kabashima, Daiki Nakashima, Kazunari Sugita, Yoko Yamada, Ryosuke Hino, YOSHIKI TOKURA · 2007 · International Journal of Cancer
  51. TIM-3 Does Not Act as a Receptor for Galectin-9
    Judith Maria Leitner, Armin Rieger, Winfried Franz Pickl, Gerhard J. Zlabinger, Katharina Grabmeier‐Pfistershammer, Peter Steinberger · 2013 · PLoS Pathogens
  52. Manipulating both the inhibitory and stimulatory immune system towards the success of therapeutic vaccination against chronic viral infections
    Sang‐Jun Ha, Erin E. West, Koichi Araki, Kendall A. Smith, Rafi Ahmed · 2008 · Immunological Reviews
  53. Chloroquine Modulates HIV-1-Induced Plasmacytoid Dendritic Cell Alpha Interferon: Implication for T-Cell Activation
    Jeffrey Martinson, Carlos Julio Montoya, Xiomara Úsuga, Rollie Ronquillo, ALAN L. LANDAY, Seema N. Desai · 2009 · Antimicrobial Agents and Chemotherapy
  54. Combination anti–PD-1 and antiretroviral therapy provides therapeutic benefit against SIV
    Geetha Mylvaganam, Lynette S. Chea, Gregory K. Tharp, Sakeenah L. Hicks, Vijayakumar Velu, Smita Swaminathan Iyer, Claire Deléage, Jacob D. Estes, Steven E. Bosinger, Gordon James Freeman et al. · 2018 · JCI Insight
  55. Dendritic cell‐based human immunodeficiency virus vaccine
    Charles R. Rinaldo · 2008 · Journal of Internal Medicine
  56. Costimulatory Pathways in Multiple Sclerosis: Distinctive Expression of PD-1 and PD-L1 in Patients with Different Patterns of Disease
    Daria Trabattoni, Marina Saresella, Michela Pacei, Ivana Marventano, Laura Mendozzi, Marco Rovaris, Domenico Caputo, Manuela Borelli, Mario Clerici · 2009 · The Journal of Immunology
  57. Potential Role for HIV-Specific CD38−/HLA-DR+ CD8+ T Cells in Viral Suppression and Cytotoxicity in HIV Controllers
    Stéphane Hua, Camille Lécuroux, Asier Sáez‐Cirión, Gianfranco Pancino, Isabelle Girault, Pierre Versmisse, Faroudy Boufassa, Olivier Tauléra, Martine Sinet, Olivier Lambotte et al. · 2014 · PLoS ONE
  58. Distinct Effector Memory CD4+ T Cell Signatures in Latent Mycobacterium tuberculosis Infection, BCG Vaccination and Clinically Resolved Tuberculosis
    Toïdi Adékambi, Chris Ibegbu, Ameeta Shivdas Kalokhe, Tianwei Yu, Susan M. Ray, Jyothi Rengarajan · 2012 · PLoS ONE
  59. Prospects for Treatment of Latent HIV
    Kirston Barton, Brandon D. Burch, Natalia Soriano-Sarabia, David M. Margolis · 2012 · Clinical Pharmacology & Therapeutics
  60. Cytokine production and dysregulation in HIV pathogenesis: Lessons for development of therapeutics and vaccines
    Morgan A. Reuter, Carolina Pombo, Michael R. Betts · 2012 · Cytokine & Growth Factor Reviews
  61. Immune Exhaustion Occurs Concomitantly With Immune Activation and Decrease in Regulatory T Cells in Viremic Chronically HIV-1–Infected Patients
    Meenakshi Sachdeva, Margaret A. Fischl, Rajendra Pahwa, Naresh Kumar Sachdeva, Savita G. Pahwa · 2010 · JAIDS Journal of Acquired Immune Deficiency Syndromes
  62. T-cell exhaustion in HIV infection
    Mohamed El Far, Rabih Halwani, Elias Anthony Said, Lydie Trautmann, Mehrnoosh Doroudchi, Loury Janbazian, Simone Gonçalves Fonseca, Julien van Grevenynghe, Bader Yassine‐Diab, Rafick‐Pierre Sékaly et al. · 2008 · Current HIV/AIDS Reports
  63. PD-1 Expression on Mycobacterium tuberculosis-Specific CD4 T Cells Is Associated With Bacterial Load in Human Tuberculosis
    Cheryl L. Day, Deborah Ann Abrahams, Rubina Bunjun, Lynnett Stone, Marwou de Kock, Gerhard Walzl, Robert John Wilkinson, Wendy A. Burgers, Willem Albert Hanekom · 2018 · Frontiers in Immunology
  64. CD8 T-Cell Memory Differentiation during Acute and Chronic Viral Infections
    Vandana Kalia, Surojit Sarkar, Rafi Ahmed · 2010 · Advances in experimental medicine and biology
  65. IL-7 decreases IL-7 receptor (CD127) expression and induces the shedding of CD127 by human CD8+ T cells
    Agatha Vranjkovic, Angela M. Crawley, Katrina Gee, Ashok Kumar, Jonathan Benjamin Angel · 2007 · International Immunology
  66. HIV-1 Tat Protein Induces Production of Proinflammatory Cytokines by Human Dendritic Cells and Monocytes/Macrophages through Engagement of TLR4-MD2-CD14 Complex and Activation of NF-κB Pathway
    Nawal Ben Haij, Rémi Planès, Kaoutar Leghmari, Manutea Christophe Serrero, Pierre Delobel, Jacques Izopet, Lbachir BenMohamed, Elmostafa Bahraoui · 2015 · PLoS ONE
  67. Foxp3+ Regulatory T Cells among Tuberculosis Patients: Impact on Prognosis and Restoration of Antigen Specific IFN-γ Producing T Cells
    Amar Ranjan Singh, Aparajita Ballave Dey, Anant Mohan, Prabhat Kumar Sharma, Dipendra Kumar Mitra · 2012 · PLoS ONE
  68. Differential control of CD4+ T‐cell subsets by the PD‐1/PD‐L1 axis in a mouse model of allergic asthma
    Jaclyn W. McAlees, Stéphane Lajoie, Krista M. Dienger, Alyssa A. Sproles, Phoebe K. Richgels, Yanfen Yang, Marat V. Khodoun, Miyuki Azuma, Hideo Yagita∥, Patricia C. Fulkerson et al. · 2015 · European Journal of Immunology
  69. Past, Current, and Future Developments of Therapeutic Agents for Treatment of Chronic Hepatitis B Virus Infection
    Yameng Pei, Chunting Wang, S. Frank Yan, Gang Liu · 2017 · Journal of Medicinal Chemistry
  70. The Balance between CD8(+) T Cell-Mediated Clearance of AAV-Encoded Antigen in the Liver and Tolerance Is Dependent on the Vector Dose
    Kumar, Sandeep R.P., Hoffman, Brad E., Terhorst, Cox, de Jong, Ype P., Herzog, Roland W. · 2017 · Molecular Therapy
  71. Alternative Serotype Adenovirus Vaccine Vectors Elicit Memory T Cells with Enhanced Anamnestic Capacity Compared to Ad5 Vectors
    Pablo Penaloza‐MacMaster, Nicholas M. Provine, Joshua Ra, Erica N. Borducchi, Anna G. McNally, Nathaniel L. Simmons, Mark Justin Iampietro, Dan H. Barouch · 2012 · Journal of Virology
  72. Impact of Anti–PD-1 and Anti–CTLA-4 on the Human Immunodeficiency Virus (HIV) Reservoir in People Living With HIV With Cancer on Antiretroviral Therapy: The AIDS Malignancy Consortium 095 Study
    Thomas A. Rasmussen, Lakshmi N. Rajdev, Ajantha Rhodes, Ashanti Dantanarayana, Surekha Tennakoon, Socheata Chea, Tim D. Spelman, Shelly Lensing, Rachel Lena Rutishauser, Sonia Bakkour et al. · 2021 · Clinical Infectious Diseases
  73. Immune activation and HIV persistence
    Hiroyu Hatano · 2013 · Current Opinion in HIV and AIDS
  74. Living in a house of cards: re‐evaluating CD8+ T‐cell immune correlates against HIV
    George Makedonas, Michael R. Betts · 2010 · Immunological Reviews
  75. PD-1 regulation in immune homeostasis and immunotherapy
    Minling Gao, Jie Shi, Xiangling Xiao, Yingmeng Yao, Xu Chen, Bin Wang, Jinfang Zhang · 2024 · Cancer Letters
  76. Telomerase activity of HIV-1–specific CD8+ T cells: constitutive up-regulation in controllers and selective increase by blockade of PD ligand 1 in progressors
    Mathias D. Lichterfeld, Danlei Mou, Thai Duong Hong Cung, Katie L. Williams, Michael T. Waring, Jinghe Huang, Florencia Pereyra, Alicja Piechocka‐Trocha, Gordon James Freeman, Eric S. Rosenberg et al. · 2008 · Blood
  77. Association of HIV-Specific and Total CD8+ T Memory Phenotypes in Subtype C HIV-1 Infection with Viral Set Point
    and the CAPRISA 002 Acute Infection Study Team, Wendy A. Burgers, Catherine Riou, Mandla Mlotshwa, Pholo W. Maenetje, Debra de Assis Rosa, Jason M. Brenchley, Koleka Patience Mlisana, Daniel C. Douek, Richard A. Koup et al. · 2009 · The Journal of Immunology
  78. Telomerase induction in T cells: A cure for aging and disease?
    Rita B. Effros · 2006 · Experimental Gerontology
  79. Safety and immunological responses to human mesenchymal stem cell therapy in difficult-to-treat HIV-1-infected patients
    Zheng Zhang, Junliang Fu, Xiangsheng Xu, Siyu Wang, Ruonan Xu, Min Zhao, Weimin Nie, Xicheng Wang, Jiyuan Zhang, Taisheng Li et al. · 2013 · AIDS
  80. Interference with PD-L1/PD-1 co-stimulation during antigen presentation enhances the multifunctionality of antigen-specific T cells
    Joeri Jan Pen, Brenda De Keersmaecker, Carlo Heirman, Jurgen Corthals, Thérèse Liechtenstein, David Escors, Kristiaan Thielemans, Karine Breckpot · 2014 · Gene Therapy
  81. 4-1BBL Induces TNF Receptor-Associated Factor 1-Dependent Bim Modulation in Human T Cells and Is a Critical Component in the Costimulation-Dependent Rescue of Functionally Impaired HIV-Specific CD8 T Cells
    Chao Wang, Tao Wen, Jean‐Pierre Routy, Nicole Flore Bernard, Rafick‐Pierre Sékaly, Tania H. Watts · 2007 · The Journal of Immunology
  82. Persistent inflammation in HIV infection: Established concepts, new perspectives
    Milena Nasi, Marcello Pinti, Cristina Mussini, Andrea Cossarizza · 2014 · Immunology Letters
  83. HLA-B*35-Px–mediated acceleration of HIV-1 infection by increased inhibitory immunoregulatory impulses
    Jinghe Huang, James J. Goedert, Eric J. Sundberg, Thai Duong Hong Cung, Patrick S. Burke, Maureen P. Martin, Liliana Preiss, Jeffrey D. Lifson, Mathias D. Lichterfeld, Mary N Carrington et al. · 2009 · The Journal of Experimental Medicine
  84. Human Immunodeficiency Virus Type 1 Nef Induces Programmed Death 1 Expression through a p38 Mitogen-Activated Protein Kinase-Dependent Mechanism
    Kar Muthumani, Andrew Y. Choo, Devon J. Shedlock, Dominick J. Laddy, Senthil G. Sundaram, Lauren A. Hirao, Ling Wu, Khanh P. Thieu, Christopher W. Chung, Karthikbabu Mallil Lankaraman et al. · 2008 · Journal of Virology
  85. Transient HIV-specific T cells increase and inflammation in an HIV-infected patient treated with nivolumab
    Gwenaëlle Le Garff, Assia Samri, Sidonie Lambert-Niclot, Sophie Even, A. Lavolé, Jacques L. Cadranel, Jean‐Philippe Spano, Brigitte Autran, Anne‐Geneviève Marcelin, Amélie Guihot · 2017 · AIDS
  86. Immune Activation and Collateral Damage in AIDS Pathogenesis
    Frank F. Miedema, Mette D. Hazenberg, Kiki Tesselaar, Debbie van Baarle, Rob J. de Boer, José A. M. Borghans · 2013 · Frontiers in Immunology
  87. HIV-1 Latency: An Update of Molecular Mechanisms and Therapeutic Strategies
    Angela Battistini, Marco Sgarbanti · 2014 · Viruses
  88. Therapeutic Vaccination with Simian Immunodeficiency Virus (SIV)-DNA+IL-12 or IL-15 Induces Distinct CD8 Memory Subsets in SIV-Infected Macaques
    Rabih Halwani, Jean Boyer, Bader Yassine‐Diab, Elias K. Haddad, Tara M. Robinson, Sanjeev Kumar, Rose M. Parkinson, Ling Wu, Maninder K. Sidhu, Rebecca Phillipson-Weiner et al. · 2008 · The Journal of Immunology
  89. Dendritic Cells: A Critical Player in Cancer Therapy?
    Anna Karolina Palucka, Hideki Ueno, Joseph W. Fay, Jacques Banchereau · 2008 · Journal of Immunotherapy
  90. Attrition of TCR Vα7.2+ CD161++ MAIT Cells in HIV-Tuberculosis Co-Infection Is Associated with Elevated Levels of PD-1 Expression
    Alireza Saeidi, Vicky L. Tien Tien, Rami Al Batran, Haider Abdulrazzaq Abed Al‐Darraji, Hong Yien Tan, Yean Kong Yong, Sasheela S L Ponnampalavanar, Muttiah Barathan, Devi Velayuthan Rukumani, Abdul Wahid Ansari et al. · 2015 · PLoS ONE
  91. Target-Dependent B7-H1 Regulation Contributes to Clearance of Central Nervous Sysyem Infection and Dampens Morbidity
    Timothy W. Phares, Chandran Ramakrishna, Gabriel Ignacio Parra, Alan L. Epstein, Lieping Chen, Roscoe Atkinson, Stephen A. Stohlman, Cornelia C. Bergmann · 2009 · The Journal of Immunology
  92. Costimulation Signals for Memory CD8+ T Cells During Viral Infections
    Priyanka A. Duttagupta, Alina C. Boesteanu, Peter D. Katsikis · 2009 · Critical Reviews in Immunology
  93. Virus‐specific CD8 T cells: activation, differentiation and memory formation
    Melanie Wiesel, Senta M. Walton, Kirsten Richter, Annette Oxenius · 2009 · Apmis
  94. A dimeric structure of PD-L1: functional units or evolutionary relics?
    Yong Chen, Peipei Liu, Feng Gao, Hao D. Cheng, Jianxun Qi, George F. Gao · 2010 · Protein & Cell
  95. Increase of cells expressing PD-L1 in bovine leukemia virus infection and enhancement of anti-viral immune responses in vitro via PD-L1 blockade
    Ryoyo Ikebuchi, Satoru Konnai, Tatsuya Shirai, Yuji Sunden, Shiro Murata, Misao Onuma, Kazuhiko Ohashi · 2011 · Veterinary Research
  96. Multiparametric Bioinformatics Distinguish the CD4/CD8 Ratio as a Suitable Laboratory Predictor of Combined T Cell Pathogenesis in HIV Infection
    Marcus Buggert, Juliet Frederiksen, Kajsa Noyan, Jenny Svärd, Babilonia Barqasho, Anders B. Sönnerborg, Ole Lund, Piotr Nowak, Annika C. Karlsson · 2014 · The Journal of Immunology
  97. Expanded T cell receptor Vβ–restricted T cells from patients with sporadic inclusion body myositis are proinflammatory and cytotoxic CD28null T cells
    Jayesh M. Pandya, Andreas E. R. Fasth, Mei Zong, Snjólaug Arnardottir, Lara Dani, Eva Lindroos, Vivianne Malmström, Ingrid E. Lundberg · 2010 · Arthritis & Rheumatism
  98. CD160-Associated CD8 T-Cell Functional Impairment Is Independent of PD-1 Expression
    Selena Viganó, Riddhima Banga, Florence Bellanger, Céline Pellaton, Alex Farina, Denis Comte, Alexandre Harari, Matthieu Perreau · 2014 · PLoS Pathogens
  99. Special regulatory T cell review: The resurgence of the concept of contrasuppression in immunoregulation
    Thomas Lehner · 2007 · Immunology
  100. Dysfunctional HIV-Specific CD8+ T Cell Proliferation Is Associated with Increased Caspase-8 Activity and Mediated by Necroptosis
    Gaurav D. Gaiha, Kevin J McKim, Matthew William Woods, Thomas Pertel, Janine Rohrbach, Natasha S. Barteneva, Christopher R. Chin, Dongfang Liu, Damien Z. Soghoian, Kevin T Cesa et al. · 2014 · Immunity