Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction

Trautmann, Lydie, Janbazian, Loury, Chomont, Nicolas, Said, Elias A, Gimmig, Sylvain, Bessette, Benoit, Boulassel, Mohamed-Rachid, Delwart, Eric +5 more·2006·Nature Medicine
DOI 10.1038/nm1482

Cited by (1,001)

Items 401–500 of 1,001

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  2. Innate Immune Sensing of HIV-1 by Dendritic Cells
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  6. Regulatory T cells in HIV infection: pathogenic or protective participants in the immune response?
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  11. Loss of the signaling adaptor TRAF1 causes CD8+ T cell dysregulation during human and murine chronic infection
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  12. Intrahepatic levels of PD-1/PD-L correlate with liver inflammation in chronic hepatitis B
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  13. Local Blockade of Epithelial PDL-1 in the Airways Enhances T Cell Function and Viral Clearance during Influenza Virus Infection
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  14. HIV Control Is Mediated in Part by CD8 + T-Cell Targeting of Specific Epitopes
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  25. Harnessing CD8+ T Cells Under HIV Antiretroviral Therapy
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  49. Dysregulation of CD8+ lymphocyte apoptosis, chronic disease, and immune regulation
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