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Requirement for CD44 in homing and engraftment of BCR-ABL-expressing leukemic stem cells
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“there was no significant difference in expression of the hyaluronan receptor, CD44, which has recently been shown to play a specific and essential role in the homing and engraftment of p210-BCR-ABLexpressing leukemia-initiating cells (Krause et al., 2006) either in vitro (Figure S1C), using cotransduced (Cre-YFP and p210-BCR-ABL-EGFP) and sorted Rac1 D/D ;Rac2 À/À LDBM cells, or in vivo (Figure S1”
From Rac Guanosine Triphosphatases Represent Integrating Molecular Therapeutic Targets for BCR-ABL-Induced Myeloproliferative Disease (2007) · cites this paper as Krause et al., 2006
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“or modify the increased cell-surface expression of CD4418 observed in Scl/p210 HSC/Ps (supplemental Figure 1F).”
From Rac2 GTPase deficiency depletes BCR-ABL+ leukemic stem cells and progenitors in vivo (2010) · cites this paper as [18]
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Weninger, W., Crowley, M. A., Manjunath, N., & von Andrian, U. H. (2001) · The Journal of Experimental Medicine · doi:10.1084/jem.194.7.953 · Cited by 515
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Cited by
Schepers, K., Pietras, E. M., Reynaud, D., Flach, J., Binnewies, M., Garg, T., Wagers, A. J., Hsiao, E. C., & Passegué, E. (2013) · Cell stem cell · doi:10.1016/j.stem.2013.06.009 · Cited by 614
Porkka, K., Koskenvesa, P., Lundán, T., Rimpiläinen, J., Mustjoki, S., Smykla, R., Wild, R., Luo, R., Arnan, M., Brethon, B., et al. (2008) · Blood · doi:10.1182/blood-2008-02-140665 · Cited by 445
Thomas, E. K., Cancelas, J. A., Chae, H.-D., Cox, A. D., Keller, P. J., Perrotti, D., Neviani, P., Druker, B. J., Setchell, K. D. R., Zheng, Y., et al. (2007) · Cancer Cell · doi:10.1016/j.ccr.2007.10.015 · Cited by 147
Age-related defects in B lymphopoiesis underlie the myeloid dominance of adult leukemia
Signer, R. A. J., Montecino-Rodriguez, E., Witte, O. N., McLaughlin, J., & Dorshkind, K. (2007) · Blood · doi:10.1182/blood-2007-01-069401 · Cited by 77
Kinstrie, R., Horne, G. A., Morrison, H., Irvine, D., Munje, C., Castañeda, E. G., Moka, H. A., Dunn, K., Cassels, J. E., Parry, N., et al. (2020) · Leukemia · doi:10.1038/s41375-019-0684-5 · Cited by 67
Rac2 GTPase deficiency depletes BCR-ABL+ leukemic stem cells and progenitors in vivo
Sengupta, A., Arnett, J., Dunn, S., Williams, D. A., & Cancelas, J. A. (2010) · Blood · doi:10.1182/blood-2009-10-247437 · Cited by 52
Metadata
- Authors
- Krause, D. S., Lazarides, K., von Andrian, U. H., & Van Etten, R. A.
- Venue
- Nature Medicine
- Published
- 2006-09-24
- Volume
- 12
- Issue
- 10
- Pages
- 1175-1180
- ISSN
- 1078-8956
- 1546-170X
- Cited by
- 349
- References
- 2
- Language
- en
- Licence
- www.springer.com/tdm (tdm)
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