The DOI matches its Crossref record; 39 of the 39 references it cites were found in a registry or an index.
Functional roles for C5a receptors in sepsis
Open accessOverview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
HMG-1 as a Late Mediator of Endotoxin Lethality in Mice
Wang, H., Bloom, O., Zhang, M., Vishnubhakat, J. M., Ombrellino, M., Che, J., Frazier, A., Yang, H., Ivanova, S., Borovikova, L., et al. (1999) · Science · doi:10.1126/science.285.5425.248 · Cited by 3,385
High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal
Lotze, M. T., & Tracey, K. J. (2005) · Nature Reviews Immunology · doi:10.1038/nri1594 · Cited by 2,487
Monocytic cells hyperacetylate chromatin protein HMGB1 to redirect it towards secretion
Bonaldi, T. (2003) · The EMBO Journal · doi:10.1093/emboj/cdg516 · Cited by 1,249
Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis
Wang, H., Liao, H., Ochani, M., Justiniani, M., Lin, X., Yang, L., Al-Abed, Y., Wang, H., Metz, C., Miller, E. J., et al. (2004) · Nature Medicine · doi:10.1038/nm1124 · Cited by 1,170
Reversing established sepsis with antagonists of endogenous high-mobility group box 1
Yang, H., Ochani, M., Li, J., Qiang, X., Tanovic, M., Harris, H. E., Susarla, S. M., Ulloa, L., Wang, H., DiRaimo, R., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2434651100 · Cited by 1,126
The chemotactic receptor for human C5a anaphylatoxin
Gerard, N. P., & Gerard, C. (1991) · Nature · doi:10.1038/349614a0 · Cited by 655
Self-citationMuller, S. (2001) · The EMBO Journal · doi:10.1093/emboj/20.16.4337 · Cited by 426
C5A Anaphylatoxin and Its Seven Transmembrane-Segment Receptor
Gerard, C., & Gerard, N. P. (1994) · Annual Review of Immunology · doi:10.1146/annurev.iy.12.040194.004015 · Cited by 416
Self-citationProtective effects of C5a blockade in sepsis
Czermak, B. J., Sarma, V., Pierson, C. L., Warner, R. L., Huber-Lang, M., Bless, N. M., Schmal, H., Friedl, H. P., & Ward, P. A. (1999) · Nature Medicine · doi:10.1038/10512 · Cited by 404
Self-citationRole of HMGB1 in apoptosis-mediated sepsis lethality
Qin, S., Wang, H., Yuan, R., Li, H., Ochani, M., Ochani, K., Rosas-Ballina, M., Czura, C. J., Huston, J. M., Miller, E., et al. (2006) · The Journal of Experimental Medicine · doi:10.1084/jem.20052203 · Cited by 400
Cited by
Complement: a key system for immune surveillance and homeostasis
Ricklin, D., Hajishengallis, G., Yang, K., & Lambris, J. D. (2010) · Nature Immunology · doi:10.1038/ni.1923 · Cited by 3,654
“, with theories ranging from decoy to regulatory or even proinflammatory function”
BackgroundImmunodesign of experimental sepsis by cecal ligation and puncture
Rittirsch, D., Huber-Lang, M. S., Flierl, M. A., & Ward, P. A. (2009) · Nature Protocols · doi:10.1038/nprot.2008.214 · Cited by 2,209
Self-citationHotchkiss, R. S., Moldawer, L. L., Opal, S. M., Reinhart, K., Turnbull, I. R., & Vincent, J.-L. (2016) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2016.45 · Cited by 1,620
HMGB1 and RAGE in Inflammation and Cancer
Sims, G. P., Rowe, D. C., Rietdijk, S. T., Herbst, R., & Coyle, A. J. (2010) · Annual Review of Immunology · doi:10.1146/annurev.immunol.021908.132603 · Cited by 1,436
Su, S., Chen, J., Yao, H., Liu, J., Yu, S., Lao, L., Wang, M., Luo, M., Xing, Y., Chen, F., et al. (2018) · Cell · doi:10.1016/j.cell.2018.01.009 · Cited by 1,230
Metadata
- Authors
- Rittirsch, D., Flierl, M. A., Nadeau, B. A., Day, D. E., Huber-Lang, M., Mackay, C. R., Zetoune, F. S., Gerard, N. P., Cianflone, K., Köhl, J., Gerard, C., Sarma, J. V., & Ward, P. A.
- Venue
- Nature Medicine
- Published
- 2008-05
- Volume
- 14
- Issue
- 5
- Pages
- 551-557
- ISSN
- 1078-8956 (ISSN-L)
- 1546-170X
- OpenAlex
- W2043825921
- Cited by
- 386
- References
- 39
- FWCI
- 10.78
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Functional roles for C5a receptors in sepsis. https://app.cochat.ai/papers/10.1038/nm1753
- The paper
- Rittirsch, D., Flierl, M. A., Nadeau, B. A., Day, D. E., Huber-Lang, M., Mackay, C. R., Zetoune, F. S., Gerard, N. P., Cianflone, K., Köhl, J., Gerard, C., Sarma, J. V., & Ward, P. A. (2008). Functional roles for C5a receptors in sepsis. Nature Medicine. https://doi.org/10.1038/nm1753
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.