Progranulin is a mediator of the wound response

He, Zhiheng, Ong, Colin H.P., Halper, Jaroslava, Bateman, Andrew·2003·Nature Medicine
DOI 10.1038/nm816

Cited by (490)

Items 301–400 of 490

  1. Crevicular Fluid and Serum Concentrations of Progranulin and High Sensitivity CRP in Chronic Periodontitis and Type 2 Diabetes
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  2. Increased Wnt Signaling and Reduced Viability in a Neuronal Model of Progranulin-Deficient Frontotemporal Lobar Degeneration
    Ana de la Encarnación, Carolina Alquézar, Ángeles Martín‐Requero · 2015 · Molecular Neurobiology
  3. Identification of biological pathways regulated by PGRN and GRN peptide treatments using transcriptome analysis
    Sara J. Rollinson, Kate Young, Janis Bennion Callister, Stuart M. Pickering-Brown · 2016 · European Journal of Neuroscience
  4. Granulin epithelin precursor promotes colorectal carcinogenesis by activating MARK/ERK pathway
    Yi Pan, ST Cheung, JOANNA H.M. TONG, Ka Yee Tin, Wei Kang, Raymond Wai Ming Lung, Feng Wu, Hui Li, Simon S.M. Ng, Tony Wing Chung Mak et al. · 2018 · Journal of Translational Medicine
  5. Gene expression advances skin reconstruction and wound repair better on silk fibroin-based materials than on collagen-based materials
    Tomoko Hashimoto, Katsura Kojima, Yasushi Tamada · 2019 · Materialia
  6. Potential role of full-length and nonfull-length progranulin in affecting aortic valve calcification
    Gaigai Huang, Liqin An, Mengtian Fan, Menghao Zhang, Bin Chen, Mengying Zhu, Jinghong Wu, Yan Liu, Yue Wang, Qin Huang et al. · 2020 · Journal of Molecular and Cellular Cardiology
  7. The Genetics of Frontotemporal Dementia
    Kristoffer Haugarvoll, Zbigniew K. Wszołek, Michael L. Hutton · 2007 · Neurologic Clinics
  8. Association Between Progranulin and β-Amyloid in Dementia With Lewy Bodies
    Gonzalo J. Revuelta, Andrea L. Rosso, Carol Frances Lippa · 2008 · American Journal of Alzheimer s Disease & Other Dementias®
  9. Acute-phase proteins in prediction of preeclampsia in patients with abnormal midtrimester uterine Doppler velocimetry
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  10. Progranulin is highly expressed in patients with chronic periodontitis and protects against experimental periodontitis in rats
    Xiao Li, Zhibin Zuo, Qian Chen, Jing Li, Wei Tang, Pishan Yang · 2018 · Journal of Periodontology
  11. Progranulin deficiency in Iba-1+ myeloid cells exacerbates choroidal neovascularization by perturbation of lysosomal function and abnormal inflammation
    Kei Takahashi, Shinsuke Nakamura, Wataru Otsu, Masamitsu Shimazawa, Hideaki Hara · 2021 · Journal of Neuroinflammation
  12. Abnormal spatiotemporal expression pattern of progranulin and neurodevelopment impairment in VPA-induced ASD rat model
    Junying Lan, Yuling Hu, Xiaoqing Wang, Wenxia Zheng, Ailing Liao, Shali Wang, Yingbo Li, Yan Wang, Feng Yang, Di Chen · 2021 · Neuropharmacology
  13. Granulin as an important immune molecule involved in lamprey tissue repair and regeneration by promoting cell proliferation and migration
    Ruixiang Sun, Dong Wang, Yuxuan Song, Qingwei Li, Peng Su, Yue Pang · 2022 · Cellular & Molecular Biology Letters
  14. Network Proteins of Human Sortilin1, Its Expression and Targetability Using Lycopene
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  15. GEP constitutes a negative feedback loop with MyoD and acts as a novel mediator in controlling skeletal muscle differentiation
    Dawei Wang, Xiaohui Bai, Qingyun Tian, Yongjie Lai, Edward A. Lin, Yongxiang Shi, Xiaodong Mu, Jian Q. Feng, Cathy Sue Carlson, C.-J. Liu · 2011 · Cellular and Molecular Life Sciences
  16. Granulin-epithelin precursor interacts with heparan sulfate on liver cancer cells
    Chi Wai Yip, Phyllis F. Cheung, Idy C.Y. Leung, Nicholas C.L. Wong, Christine Kei Chin Cheng, Sheung Tat Fan, ST Cheung · 2014 · Carcinogenesis
  17. Recent advances in the study of progranulin and its role in sepsis
    Gang Tian, Xinrui Jin, Qin Wang, Ting Ye, Guangrong Li, Jinbo Liu · 2019 · International Immunopharmacology
  18. Progranulin regulation of autophagy contributes to its chondroprotective effect in osteoarthritis
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  19. Progranulin is essential for bone homeostasis and immunology
    Qian Chen, Zuping Wu, Liang Xie · 2022 · Annals of the New York Academy of Sciences
  20. Regulation of chondrocyte differentiation by IRE1α depends on its enzymatic activity
    Fengjin Guo, Rong Jiang, Xiangzhu Li, Peng Zhang, Xiaofeng Han, C.-J. Liu · 2014 · Cellular Signalling
  21. Increased progranulin in the skin of amyotrophic lateral sclerosis: An immunohistochemical study
    Kanako Yasui, Yoshihiko Oketa, Kazuhiro Higashida, Hiroyuki Fukazawa, Seiitsu Ono · 2011 · Journal of the Neurological Sciences
  22. Lightwave-reinforced stem cells with enhanced wound healing efficacy
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  23. Modified Yeast-Two-Hybrid System to Identify Proteins Interacting with the Growth Factor Progranulin
    Qingyun Tian, Yunpeng Zhao, C.-J. Liu · 2012 · Journal of Visualized Experiments
  24. Are progranulin levels associated with polycystic ovary syndrome and its possible metabolic effects in adolescents and young women?
    Ali Özgür Ersoy, Aytekin Tokmak, Sibel Özler, Efser Öztaş, Ebru Ersoy, Hüseyin Tuğrul Çelik, Hüsamettin Erdamar, Nafiye Yılmaz · 2016 · Archives of Gynecology and Obstetrics
  25. Signaling Pathway of GP88 (Progranulin) in Breast Cancer Cells: Upregulation and Phosphorylation of c-myc by GP88/Progranulin in Her2-Overexpressing Breast Cancer Cells
    Wes E. Kim, Binbin Yue, Ginette Serrero · 2015 · Breast Cancer Basic and Clinical Research
  26. Progranulin regulates neurogenesis in the developing vertebrate retina
    Caroline E. Walsh, Peter F. Hitchcock · 2017 · Developmental Neurobiology
  27. Role of clusterin/progranulin in toluene diisocyanate-induced occupational asthma
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  28. Progranulin Promotes Bleomycin-Induced Skin Sclerosis by Enhancing Transforming Growth Factor–β/Smad3 Signaling through Up-Regulation of Transforming Growth Factor–β Type I Receptor
    Ting Yang, Xuemei Zhang, Aijun Chen, Yunju Xiao, Si Sun, Jurong Yan, Yuwei Cao, Jin Chen, Feng‐Zeng Li, Qun Zhang et al. · 2019 · American Journal Of Pathology
  29. Neuromuscular Disorders in Zebrafish: State of the Art and Future Perspectives
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  30. The Glycoprotein Growth Factor Progranulin Promotes Carcinogenesis and has Potential Value in Anti-cancer Therapy
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  31. Down‐regulation of mir‐27b promotes angiogenesis and fibroblast activation through activating PI3K/AKT signaling pathway
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  32. GP88 (Progranulin) Confers Fulvestrant (Faslodex, ICI 182,780) Resistance to Human Breast Cancer Cells
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  33. RNA interference against granulin-epithelin precursor prevents hepatocellular carcinoma growth: Its application as a therapeutic agent
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  34. A novel granulin homologue isolated from the jellyfish Cyanea capillata promotes proliferation and migration of human umbilical vein endothelial cells through the ERK1/2-signaling pathway
    Chao Wang, Beilei Wang, Bo Wang, Qianqian Wang, Guoyan Liu, Chongxu Fan, Liming Zhang · 2019 · International Journal of Biological Macromolecules
  35. Adipose tissue and adipose secretome in systemic sclerosis
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  36. Progranulin Protects Against Osteoporosis by Regulating Osteoclast and Osteoblast Balance via TNFR Pathway
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  37. ADAM15 participates in fertilization through a physical interaction with acrogranin
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  38. Progranulin overproduction due to constitutively activated c-Abl/PKC-δ/Fli1 pathway contributes to the resistance of dermal fibroblasts to the anti-fibrotic effect of tumor necrosis factor-α in localized scleroderma
    Takuya Miyagawa, Yohei Ichimura, Kouki Nakamura, Megumi Hirabayashi, Takashi Yamashita, Ryosuke Saigusa, Shunsuke Miura, Takehiro Takahashi, Tetsuo Toyama, Takashi Taniguchi et al. · 2018 · Journal of Dermatological Science
  39. Innate Anti-microbial and Anti-chemotaxis Properties of Progranulin in an Acute Otitis Media Mouse Model
    Zimeng Wang, Qian He, Xinxin Zhang, Yurong Ma, Fangmei Fan, Yilin Dong, Wenchun Xu, Yibing Yin, Yujuan He · 2018 · Frontiers in Immunology
  40. Frontotemporal lobar degeneration: clinical and pathologic overview
    Gil Dan Rabinovici, Katya Rascovsky, Bruce L. Miller · 2008 · Handbook of clinical neurology
  41. Diagnostic value of progranulin in patients with lupus nephritis and its correlation with disease activity
    Jiabin Wu, Lixin Wei, Weiming Wang, Xianghui Zhang, Li Chen, Changda Lin · 2016 · Rheumatology International
  42. Progranulin: A proangiogenic factor in visceral adipose tissue in tumoral and non‑tumoral visceral pathology
    Ioana Daniela Binişor, Ileana Monica Baniţă, Dragoş Ovidiu Alexandru, MIHAELA CEZARINA MEHEDINTI, Sanda Jurja, Ana Marina Andrei, Cătălina Gabriela Pisoschi · 2021 · Experimental and Therapeutic Medicine
  43. A granulin-positive macrophage subtype in mycobacterial granulomas alleviates tissue damage by limiting excessive inflammation
    Geyang Luo, Yanling Wen, Min Wang, Hao Wang, Duoduo Li, Mingfeng Liao, Dong Zeng, Sizhu Luo, Liangfei Niu, Tao Sun et al. · 2025 · Proceedings of the National Academy of Sciences
  44. Functional characterization and molecular mechanism exploration of three granulin epithelin precursor splice variants in biomineralization of the pearl oyster Pinctada fucata
    Mi Zhao, Maoxian He, Xiande Huang, Qi Wang, Yu Shi · 2015 · Molecular Genetics and Genomics
  45. Generation of a novel HEK293 luciferase reporter cell line by CRISPR/Cas9-mediated site-specific integration in the genome to explore the transcriptional regulation of the PGRN gene
    Yanqing Li, Sai Li, Yan Li, Haibin Xia, Qinwen Mao · 2019 · Bioengineered
  46. Effect of a coronary-heart-disease-associated variant of ADAMTS7 on endothelial cell angiogenesis
    Xiangyuan Pu, Kenneth Chan, Wei Yang, Qingzhong Xiao, Li Zhang, Andrew D. Moore, C.-J. Liu, Tom R. Webb, Mark J. Caulfield, Nilesh J. Samani et al. · 2020 · Atherosclerosis
  47. Label-Free Mass Spectrometry-Based Quantitative Proteomics Analysis of Serum Proteins During Early Pregnancy in Jennies (Equus asinus)
    Liang Deng, Yuwei Han, Chi Tang, Qingchao Liao, Zheng Li · 2020 · Frontiers in Veterinary Science
  48. Upregulated expression level of the growth factor, progranulin, is associated with the development of primary Sjögren’s syndrome
    Ni Zhang, Ning Yang, QILIN CHEN, Feng Xian Qiu, Xing-Fu Li · 2014 · Experimental and Therapeutic Medicine
  49. Progranulin deficiency exacerbates cardiac remodeling after myocardial infarction
    Takahiro Sasaki, Yoshiki Kuse, Shinsuke Nakamura, Masamitsu Shimazawa, Hideaki Hara · 2023 · FASEB BioAdvances
  50. Progranulin: A promising biomarker and therapeutic target for fibrotic diseases
    Fan Yang, Ming-Han Cheng, Hai‐Feng Pan, Jian Xin Gao · 2024 · Acta Pharmaceutica Sinica B
  51. Progranulin enhances the engraftment of transplanted human iPS cell-derived cerebral neurons
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  52. Progranulin Stimulates Proliferation of Mouse Pancreatic Islet Cells and Is Overexpressed in the Endocrine Pancreatic Tissue of an MEN1 Mouse Model
    Andreea R. Barbu, Margareta Halin Lejonklou, Britt M. Skogseid · 2015 · Pancreas
  53. Determination of GP88 (progranulin) expression in breast tumor biopsies improves the risk predictive value of the Nottingham Prognostic Index
    Ginette Serrero, Douglas M. Hawkins, P.A. Bejarano, Olga B. Ioffe, Katherine Tkaczuk, Robert E. Elliott, Jonathan F. Head, Jeffrey T. Phillips, Andrew K. Godwin, JoEllen Weaver et al. · 2016 · Diagnostic Pathology
  54. MiR-145 mediates zebrafish hepatic outgrowth through progranulin A signaling
    Ya‐Wen Li, Keng-Yu Chiang, Yen-Hsing Li, Sung–Yu Wu, Wangta Liu, Chia-Ray Lin, Jen‐Leih Wu · 2017 · PLoS ONE
  55. Granulin-epithelin precursor interacts with 78-kDa glucose-regulated protein in hepatocellular carcinoma
    Chi Wai Yip, Ching Yan Lam, Terence Chuen Wai Poon, Tan To Cheung, Phyllis F. Cheung, Sze Wai Fung, Xiao Qi Wang, Idy C.Y. Leung, Linda W.C. Ng, Chung Mau Lo et al. · 2017 · BMC Cancer
  56. Granulin Expression in Hamsters during Opisthorchis viverrini Infection-Induced Cholangiocarcinogenesis
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  57. FRONTOTEMPORAL DEMENTIA
    Indre V. Viskontas, Bruce L. Miller · 2007 · CONTINUUM Lifelong Learning in Neurology
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  59. The role of progranulin in ischemic heart disease and its related risk factors
    Asma Mohammed Alyahya · 2022 · European Journal of Pharmaceutical Sciences
  60. Skin Tape Strip Proteomics in Mycosis Fungoides Identifies Tumor-Associated Biomarkers
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  61. GRN−/− iPSC-derived cortical neurons recapitulate the pathological findings of both frontotemporal lobar degeneration and neuronal ceroidolipofuscinosis
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  62. Growing a tumor stroma: a role for granulin and the bone marrow
    Andrew Bateman · 2011 · Journal of Clinical Investigation
  63. Biological function analysis of monoclonal antibodies against human granulins in vitro using U251 cells as a model
    Yanqing Li, Ya Li, Mingfu Ye, Dongyang Wang, Junli Zhao, Xiaohong Sun, Qinwen Mao, Haibin Xia · 2016 · Protein Expression and Purification
  64. Alveolar macrophage-derived progranulin mediated pro-inflammatory Il-6 expression via regulating Creb1 in silicosis model
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