Progranulin is a mediator of the wound response
He, Zhiheng, Ong, Colin H.P., Halper, Jaroslava, Bateman, Andrew·2003·Nature Medicine
DOI 10.1038/nm816
Cited by (490)
Items 401–490 of 490
- Progranulin Protects against Aspergillus fumigatus Keratitis by Attenuating the Inflammatory Response through Enhancing AutophagyPingli Qi, Xing Liu, Cui Li, Qiang Xu, Liting Hu, Huijin Duan, Guiqiu Zhao, Jing Lin · 2024 · ACS Infectious Diseases
- Adipose-derived stem cell transplantation enhances spinal cord regeneration by upregulating PGRN expressionQiongchi Zhang, Jingtao Wu, Dong Sheng Guo, Ning Ji, Weidong Liu, Xinyu Li, Hao Liu, Chengyi Zhang, Min-Chao Zhao, Haopeng Li et al. · 2024 · Neuroreport
- Methods to Investigate the Roles of Progranulin in Angiogenesis Using In Vitro Strategies and Transgenic Mouse ModelsHuishi Toh, Eugene Daniels, Andrew Bateman · 2018 · Methods in molecular biology
- Potential effects of progranulin and granulins against retinal photoreceptor cell degeneration.Miruto Tanaka, Yoshiki Kuse, Shinsuke Nakamura, Hideaki Hara, Masamitsu Shimazawa · 2019 · PubMed Central
- Identification of potential biological processes and key genes in diabetes-related stroke through weighted gene co-expression network analysisYong He, Yang Bai, Qin Huang, Jian Xia, Jie Feng · 2024 · BMC Medical Genomics
- Meeting Between Rumi and Shams in Notch Signaling; Implications for Pain Management: A Narrative ReviewSamira Rajaei, Yousef Fatahi, Ali Dabbagh · 2019 · Anesthesiology and Pain Medicine
- Association of Progranulin Gene Expression from Dyspeptic Patients with Virulent Helicobacter pylori Strains; In Vivo ModelClaudia Troncoso, Mónica Pávez, Álvaro Cerda, Victor Manríquez, Aurora Prado, Edmundo Hofmann, Eddy Ríos, Armando Sierralta, Luis Copelli, Leticia Barrientos · 2022 · Microorganisms
- Progranulin facilitates the increase of platelet count in immune thrombocytopeniaYingyi Yu, Yuanyuan Shi, Xinyi Zuo, Qi Feng, Yaping Hou, Wei Tang, Fan Yi, Fan Yi, Ming Hou, Yuan Yu et al. · 2018 · Thrombosis Research
- Mice Treated Subcutaneously with Mouse LPS-Converted PrPres or LPS Alone Showed Brain Gene Expression Profiles Characteristic of Prion DiseaseDagnachew Hailemariam, Seyed Ali Goldansaz, Nathalie Daude, David Scott Wishart, Burim Namik Ametaj · 2021 · Veterinary Sciences
- Progranulin and Inflammation‐Induced Cancer: An Important Player in the Tumor Microenvironment?Gaia Insinga, Caterina Tomassetti, Vrunda Satasiya, Francesca Gimigliano, Antonio Giordano, Emanuele Giurisato, Andrea Morrione · 2026 · Journal of Cellular Physiology
- Clinical utility of progranulin in patients with systemic lupus erythematosusSally Said Abd Elhamed, ReemM Ibrahem, KhalidaE ElRefaie, EmanM.S Elbagoury · 2020 · Al-Azhar Assiut Medical Journal
- Serum GP88 as a predictive biomarker for hepatocellular carcinoma in patients with viral hepatitis C after direct-acting antiviral agentsHidekazu Ishida, Masao Takemura, Atsushi Suetsugu, Takafumi Naiki, Takuji Tanaka, Eiichi Tomita, Ginette Serrero, Hidetoshi Matsunami, Yasuko Yamamoto, Kuniaki Saito · 2021 · Annals of Clinical Biochemistry International Journal of Laboratory Medicine
- Long non-coding RNA LINC01194 promotes the inflammatory response and apoptosis of lipopolysaccharide-treated MLE-12 cells through the miR-203a-3p/MIP-2 axisYuyao Shen, Senwei Zhao, Minglei Hua · 2021 · Canadian Journal of Physiology and Pharmacology
- Serum progranulin level is a novel tool for monitoring disease activity of dermatomyositis with antimelanoma differentiation‐associated protein 5 antibodiesAsami Fujii, Yuki H. Mizutani, Miho Kawamura, Kanako Matusyama, Yoko Mizutani, En Shu, Mariko Seishima · 2021 · Journal of Cutaneous Immunology and Allergy
- Covalent conjugates of granulin-epithelial precursor-siRNA with arginine-rich peptide for improved stability and intracellular delivery in hepatoma cellsDa Hyeon Choi, Jue‐Yeon Lee, Jae‐Hwan Nam, Yang‐Hoon Kim, Yoon Jeong Park, Yoon Shin Park · 2019 · Molecular & Cellular Toxicology
- The effect of non‐surgical periodontal treatment on progranulin levelsAyşegül Sarı, Pasquale Santamaria, Luigi Nibali · 2025 · Journal of Periodontology
- Blend Nanofibers (Natural and Synthetic Polymers) for Wound HealingAditya Dev Rajora, Trishna Bal, Karmabeer Jena, Subhendu Chakroborty, Ashutosh Gupta, Balaji Ayyanar Chinnapan · 2025 · Royal Society of Chemistry eBooks
- The biology and pathophysiology of the proatherogenic metalloprotease ADAMTS7Shiwali Goyal, James Muniu, Mohd Akbar Bhat, Eli P Oldham, Derrick W. Pruitt, Luis Frias Perez, Frida Z. Miranda, Joshua Muia · 2026 · Open Biology
- Progranulin Is a Useful Biomarker to Predict Mortality in ICU Patients with Low Burden of Organ DysfunctionJochen Johannes Schoettler, Lutz Pridzun, Bertram Flehmig, Holger A. Lindner, Verena Schneider‐Lindner, Joerg Krebs, Franz-Simon Centner, Manfred Thiel · 2026 · Biomedicines
- Can serum progranulin levels be a biomarker following gastric ulcer therapy?Evrim Kahramanoğlu Aksoy, Ferdane PİRİNÇÇİ SAPMAZ, Özlem Doğan, Özgür Albuz, Metın Uzman, Yaşar Nazlıgül · 2018 · Gastroenterology Review
- Granulin+ Macrophages Promote Lineage Plasticity in Prostate Cancer Through Paracrine Signaling LoopsZhipeng Zhu, Mi Zhang, Ying Song, Wei Jiang, Fang Cao, Yicong Yao, Xiaotong Yu, Hongyu Zhao, Husile Baiyin, De Chang et al. · 2026 · Genomics Proteomics & Bioinformatics
- Regulation of microglial activation by progranulin through the NF-κB pathway in subarachnoid hemorrhage and its effect on white matter injuryZiliang Hu, Pan Lv, Wenting Lan, Menglu Shen, Yi Huang, Chengzhi Chen, Yan Zheng, Kaixuan Chen, Xiang Gao, Wei Cui et al. · 2026 · Neurotherapeutics
- Frontotemporal dementiaIndre V. Viskontas, Bruce L. Miller · 2009 · Cambridge University Press eBooks
- Progranulin and insulin-like Growth Factor Binding Protein-2 as Biomarkers of Disease Activity and Pathological Changes in Lupus NephritisSamar H. Goma, Marwa Mahmoud Abdelaziz, Eman H. El-Hakeim, Mona Hussein El Zohri, Sohair Sayed · 2017 · Aktuelle Rheumatologie
- Methods for Studying the Function of Progranulin in Atherosclerosis Using Both Knockout Mice Models and In Vitro StudiesTohru Ohama, Ryota Kawase, Yasushi Sakata, Shizuya Yamashita · 2018 · Methods in molecular biology
- Systematic evaluation of species-independent serum pre-fractionation strategies revealed cost-effective methods to reduce proteome complexityAnkan De, Tapan Kumar Dutta, Mohammad Ayub Ali, Parthasarathi Behera, Jagan Mohanarao Gali · 2019 · Analytical Biochemistry
- Elevated plasma progranulin levels in the acute phase are correlated with recovery of left ventricular function in the chronic phase in patients with acute myocardial infarctionShingo Minatoguchi, Atsushi Satake, Hirotaka Murase, Ryo Yoshizumi, Hisaaki Komaki, Shinya Baba, Shinji Yasuda, Shinsuke Ojio, Toshiki Tanaka, Hiroyuki Okura et al. · 2024 · PLoS ONE
- Effect of overexpression of GRN on the proliferation and osteogenic capacity of human periodontal cellsXuanxuan Yao, Ruoshan Qin, Ziwei Cui, Dengqi He, Xiaorong Sun, Yuefeng Sun, Xiangyi He · 2024 · Experimental and Therapeutic Medicine
- The C-terminal region of Opisthorchis viverrini granulin-1 promotes cell proliferation in the absence of regular secondary structureMohadeseh Dastpeyman, David T. R. Wilson, Alex C. Loukas, Michael J. Smout, Norelle L. Daly · 2025 · Australian Journal of Chemistry
- Porcine granulin gene (GRN): Molecular cloning, polymorphism and chromosomal localizationJine Yang, Mei Yu, Bang Liu, Mengjin Zhu, Kui Li · 2006 · DNA sequence
- Molecular Mechanisms and Biomarker Perspective of MicroRNAs in Traumatic Brain Injury2014 · CRC Press eBooks
- Methods to Study the Role of Progranulin in the Tumor MicroenvironmentMoshe Elkabets, Samuel Brook · 2018 · Methods in molecular biology
- RESISTINA Y OTRAS ADIPOQUINAS: PAPEL EN LA OBESIDAD, DIABETES E INSULINORESISTENCIAPaola Valero, Aida J. Souki, Nailet Josefina Arráiz Rodríguez, Carem Prieto Fuenmayor, Clímaco Cano-Ponce · 2018 · Ediciones Universidad Simón Bolívar eBooks
- Pleiotropic Protective Effects of Progranulin in the Treatment of Ischemic StrokeMasato Kanazawa, Kunio Kawamura, Tetsuya Takahashi, Takayoshi Shimohata · 2019 · Springer eBooks
- A szénhidrát-anyagcsere és a gyulladásos folyamatok jellemzésére szolgáló új marker, a szérumprogranulin diagnosztikai és prognosztikai szerepérőlBíborka Nádró, Ferenc Sztanek, Hajnalka Lőrincz, Dénes Páll, György Paragh, Mariann Harangi · 2019 · Orvosi Hetilap
- Exploring the interactions between interleukin-8 (IL8) and amyloid-β (Aβ) peptide in traumatic brain injuryOlivia G Gibson · 2013 · Aquila Digital Community (University of Southern Mississippi)
- Frontotemporal DementiaChristian W. Wider, Dennis W. Dickson, Rosa Rademakers, Zbigniew K. Wszołek · 2009 · Blue books of neurology
- Cloning, characterization and expression analysis of a cDNA encoding granulin gene in Nile tilapia (Oreochromis niloticus).M. K. Mar, Nontawith Areechon, S. S. de Silva, Thuy Thi Thanh Nguyen, Prapansak Srisapoome · 2009
- OVEREXPRESSION OF PROGRANULIN INCREASES CELLS IN GROWTH PHASE BUT IS INSUFFICIENT TO INDUCE SKIN TUMOR FORMATIONMaki Kato, Naoko Hasunuma, Satoshi Itami, Motomu Manabe, Shin‐Ichi Osada · 2009 · Institutional Repositories DataBase (IRDB)
- Efeito do tratamento com fatores hepatotróficos em ratas (Wistar) induzidas experimentalmente à cirrose por TioacetamidaRicardo Romão Guerra · 2006 · Digital Library of Theses and Dissertations (Universidade de São Paulo)
- Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 1284 Angiogenesis Related Markers In Non-Small Cell Lung CancerDaniel Brattström · 2003
- Factors in glutamate excitotoxicity, inflammation and epilepsyShanshan Zhu · 2012 · cIRcle (University of British Columbia)
- Multiple therapeutic effects of a growth factor, progranulin on ischemic brain injuryTakayoshi Shimohata, Masato Kanazawa, Masafumi Toriyabe, Misaki Koyama, Tetsuya Takahashi, Masatoyo Nishizawa · 2016 · Cerebral Blood Flow and Metabolism (Japanese journal of cerebral blood flow and metabolism)
- Identification of a role for B7-H4 in neutrophil homeostasis and innate immunityMathew M. Augustine · 2014
- Periodontal Host Response in Subjects with ObesityHideaki Hayashida, Reiko Furugen, Toshiyuki Saito · 2018 · Current Oral Health Reports
- Neural Stem/Progenitor Cells and ProgranulinTaku Nedachi · 2019 · Springer eBooks
- Molecular and Functional Properties of ProgranulinMasugi Nishihara · 2019 · Springer eBooks
- PGRN and Neurodegenerative Diseases Other Than FTLDMasato Hosokawa · 2019 · Springer eBooks
- Progranulin Protects Rat Testis From Ischaemic Reperfusion InjuryM.D. NAGLAA A. AHMED EMAN R. ABOZAID · 2019 · The Medical Journal of Cairo University/The Medical Journal of Cairo University
- Dynamic changes in the urine proteome of tumor-bearing mouse models of B16 melanoma and RM-1 prostate cancerLujun Li, Xuanzhen Pan, Yongtao Liu, Ting Wang, Youhe Gao · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- Therapeutic strategies for vascular protection after acute ischemic strokeMasafumi Toriyabe, Masato Kanazawa, Takayoshi Shimohata · 2019 · Japanese Journal of Thrombosis and Hemostasis
- Protein Plasticity and its Role in Cellular FunctionsSidra Ilyas, Abdul Manan · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- Premature termination codon readthrough restores progranulin expression in preclinical models of frontotemporal dementia and neuronal ceroid lipofuscinosisJonathan Frew · 2021 · cIRcle (University of British Columbia)
- Auswirkungen eines zwölfmonatigen kontrollierten Trainingsprogramms auf die Leptin-, Adiponectin- und Progranulin-Serumkonzentrationen sowie Parameter des Lipidstoffwechsels bei Patienten mit Typ 2 DiabetesWiebke Schaarschmidt · 2010 · Qucosa (Saxon State and University Library Dresden)
- Angiogenesis related markers in non-small cell lung cancer.Daniel Brattström · 2003 · KTH Publication Database DiVA (KTH Royal Institute of Technology)
- Tumor Co-Expression of Progranulin and Sortilin Identifies a Highly Malignant Subgroup of Breast CancerKaroline Berger, Sara Rhost, Svanheiður Rafnsdóttir, Éamon Hughes, Ylva Magnusson, Maria Ekholm, Olle Stål, Lisa Rydén, Göran Landberg · 2020 · Research Square
- Molecular Mechanisms and Biomarker Perspective of MicroRNAs in Traumatic Brain InjuryNagaraja S. Balakathiresan, Anuj Kumar Sharma, Raghavendar Chandran, Manish Bhomia, Zhiqun Zhang, Kevin Wang, Radha K. Maheshwari · 2014 · CRC Press eBooks
- No Correlation between Serum Progranulin Levels and Severity of Diabetic Retinopathy in Chinese People with Type 2 Diabetes and Normal or Mildly Impaired Renal FunctionHaiyan Cheng, lan xu, Ruifang Bu, cheng jiang, lijun yao, Wenjun Wu · 2020
- RETRACTED: Antibacterial and therapeutic effects of Vancomycin-resistant Staphylococcus aureus bacteriocin (VRSAcin) in treatment of VRSA skin infection in miceahmed qassam, Mais Emad Ahmed · 2024 · Research Square · Retracted
- Male‐pronuclei‐specific granulin facilitates somatic cells reprogramming via mitigating excessive cell proliferation and enhancing lysosomal functionQingqing Wei, Yanwen Xu, Guina Cui, Jiatong Sun, Zhongqu Su, Xiaochen Kou, Yanhong Zhao, Suyuan Cao, Wenhui Li, Yiliang Xu et al. · 2024 · Journal of Cellular Physiology
- Restraint of melanoma progression by cells in the local skin environmentYilun Ma, Mohita M. Tagore, Miranda V. Hunter, Ting Hsiang Huang, Emily D. Montal, Joshua M. Weiss, Yingxiao Shi, Tuulia Vallius, Peter Karl Sorger, Richard Mark White · 2026 · eLife
- Reviewer #2 (Public review): Restraint of melanoma progression by cells in the local skin environment2024 · eLife
- Restraint of melanoma progression by cells in the local skin environmentYilun Ma, Mohita M. Tagore, Miranda V. Hunter, Ting Hsiang Huang, Emily D. Montal, Joshua M. Weiss, Richard Mark White · 2024 · eLife
- Restraint of melanoma progression by cells in the local skin environmentYilun Ma, Mohita M. Tagore, Miranda V. Hunter, Ting Hsiang Huang, Emily D. Montal, Joshua M. Weiss, Yingxiao Shi, Tuulia Vallius, Peter Karl Sorger, Richard Mark White · 2024 · eLife
- Advances in Biomarkers for Early Diagnosis of Early-Onset Neonatal Sepsis妤 熊 · 2025 · Advances in Clinical Medicine
- Research Progress on the Role of Progranulin in Kidney Injury媛媛 卢 · 2025 · Advances in Clinical Medicine
- Analysis of progranulin concentration in corneal epithelium and tears as a possible biomarker in the clinical diagnosis and progression of keratoconusGülben Akcan, Eda Nur Gönültaş Özkan, Gamze Dereli Can · 2025 · International Ophthalmology
- Synergistic cooperation between progranulin and Jak2/Stat3 signaling determines definitive myeloid cell fateAbbigail McCune, Masuma Khatun Usha, Inga Baldus, C.J. Willett, Noemi Ferrito, Radwa Barakat, Emilee Clemensen, Elizabeth Snella, Mark Morton, Jesús Lacal et al. · 2025 · Cell Reports
- Additional file 6 of Tumor co-expression of progranulin and sortilin as a prognostic biomarker in breast cancerKaroline Berger, Sara Rhost, Svanheiður Rafnsdóttir, Hughes, Éamon, Ylva Magnusson, Ekholm, Maria, Stål, Olle, Rydén, Lisa, Göran Landberg · 2021 · Figshare
- Additional file 1 of Granulin as an important immune molecule involved in lamprey tissue repair and regeneration by promoting cell proliferation and migrationRuixiang Sun, Wang, Dong, Song, Yuxuan, Li, Qingwei, Peng Su, Pang, Yue · 2022 · Figshare
- Additional file 3 of Progranulin from different gliocytes in the nucleus accumbens exerts distinct roles in FTD- and neuroinflammation-induced depression-like behaviorsWang, Jing, Simin Lai, Zhou, Ting, Zhihao Xia, Li, Weina, Wenqi Sha, JINGJIE LIU, Chen, Yanjiong · 2024 · Figshare
- Additional file 3 of Tumor co-expression of progranulin and sortilin as a prognostic biomarker in breast cancerKaroline Berger, Sara Rhost, Svanheiður Rafnsdóttir, Hughes, Éamon, Ylva Magnusson, Ekholm, Maria, Stål, Olle, Rydén, Lisa, Göran Landberg · 2021 · Figshare
- Additional file 1 of Tumor co-expression of progranulin and sortilin as a prognostic biomarker in breast cancerKaroline Berger, Sara Rhost, Svanheiður Rafnsdóttir, Hughes, Éamon, Ylva Magnusson, Ekholm, Maria, Stål, Olle, Rydén, Lisa, Göran Landberg · 2021 · Figshare
- Additional file 4 of Progranulin from different gliocytes in the nucleus accumbens exerts distinct roles in FTD- and neuroinflammation-induced depression-like behaviorsWang, Jing, Simin Lai, Zhou, Ting, Zhihao Xia, Li, Weina, Wenqi Sha, Liu, Jingjie, Chen, Yanjiong · 2024 · Figshare
- Additional file 1 of Progranulin from different gliocytes in the nucleus accumbens exerts distinct roles in FTD- and neuroinflammation-induced depression-like behaviorsWang, Jing, Simin Lai, Zhou, Ting, Zhihao Xia, Li, Weina, Wenqi Sha, Liu, Jingjie, Chen, Yanjiong · 2024 · Figshare
- Additional file 5 of Tumor co-expression of progranulin and sortilin as a prognostic biomarker in breast cancerKaroline Berger, Sara Rhost, Svanheiður Rafnsdóttir, Hughes, Éamon, Ylva Magnusson, Ekholm, Maria, Stål, Olle, Rydén, Lisa, Göran Landberg · 2021 · Figshare
- Additional file 2 of Tumor co-expression of progranulin and sortilin as a prognostic biomarker in breast cancerKaroline Berger, Sara Rhost, Svanheiður Rafnsdóttir, Hughes, Éamon, Ylva Magnusson, Ekholm, Maria, Stål, Olle, Rydén, Lisa, Göran Landberg · 2021 · Figshare
- Additional file 4 of Tumor co-expression of progranulin and sortilin as a prognostic biomarker in breast cancerKaroline Berger, Sara Rhost, Svanheiður Rafnsdóttir, Hughes, Éamon, Ylva Magnusson, Ekholm, Maria, Stål, Olle, Rydén, Lisa, Göran Landberg · 2021 · Figshare
- Additional file 1 of Identification of potential biological processes and key genes in diabetes-related stroke through weighted gene co-expression network analysisHe, Yong, Bai, Yang, Huang, Qin, Jian Xia, Feng, Jie · 2024 · Figshare
- Additional file 2 of Progranulin from different gliocytes in the nucleus accumbens exerts distinct roles in FTD- and neuroinflammation-induced depression-like behaviorsWang, Jing, Simin Lai, Zhou, Ting, Zhihao Xia, Li, Weina, Wenqi Sha, Liu, Jingjie, Chen, Yanjiong · 2024 · Figshare
- Etude du continuum mécanistique et physiopathologique entre la Sclérose Latérale Amyotrophique et la Démence FrontoTemporaleRobin Waegaert · 2019 · theses.fr (ABES)
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- Differential lysosomal burden in the excitatory and inhibitory neurons of the FTD-GRN brain.John Joyce · 2023
- Progranulin enhances complement component 5a–primed neutrophil activation in antineutrophil cytoplasmic antibody–associated vasculitisYuan-Yuan Lu, Xingyu Chen, Tiegang Lv, Jian Hao · 2026 · Immunology Letters
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- An Optimized Stem Cell Secretome Proteomics Platform: Application to Progranulin-Deficient iPSCsJiawei Ni, Hope S. Tracey, Ling Hao · 2026 · Journal of Proteome Research
- Single-cell RNA-seq analysis reveals the role of PGRN in modulating fibroblast heterogeneity and enhancing wound healing殷文江, Chaohang Chen, Qixin Chen, Xulong Huang, Zhong Zhou, Chunming Zhao, Xingru Liu, Jingyuan Ma, Zhouru Li, Shanshan Li · 2026 · Frontiers in Bioengineering and Biotechnology
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