Controlled gene expression in primary Lgr5 organoid cultures

Koo, Bon-Kyoung, Stange, Daniel E, Sato, Toshiro, Karthaus, Wouter, Farin, Henner F, Huch, Meritxell, van Es, Johan H, Clevers, Hans·2012·Nature Methods

Cited by (322)

Items 201–300 of 322

  1. Introducing the Stem Cell ASCL2 Reporter STAR into Intestinal Organoids
    Maria C. Heinz, Koen C. Oost, Hugo J.G. Snippert · 2020 · STAR Protocols
  2. Segregation of the stemness program from the proliferation program in intestinal stem cells
    Yuan Liu, Meimei Huang, Xiaodan Wang, Zinan Liu, Siqi Li, Ye‐Guang Chen · 2023 · Stem Cell Reports
  3. Adult stem cell lineage tracing and deep tissue imaging
    Juergen Fink, Amanda Andersson-Rolf, Bon‐Kyoung Koo · 2015 · BMB Reports
  4. Conformation-specific inhibitors of activated Ras GTPases reveal limited Ras dependency of patient-derived cancer organoids
    Svenja Wiechmann, Pierre Maisonneuve, Britta Moyo Grebbin, Meike Hoffmeister, Manuel Kaulich, Hans C. Clevers, Krishnaraj Rajalingam, Igor V. Kurinov, Henner F. Farin, Frank Sicheri et al. · 2020 · Journal of Biological Chemistry
  5. Generation of Human Stomach Cancer iPSC-Derived Organoids Induced by Helicobacter pylori Infection and Their Application to Gastric Cancer Research
    Chia‐Chen Ku, Kenly Wuputra, Jia-Bin Pan, Chia-Pei Li, Chung‐Jung Liu, Yi‐Chang Liu, Shigeo Saito, Te‐Fu Chan, Chang‐Shen Lin, Deng‐Chyang Wu et al. · 2022 · Cells
  6. Retroviral Transduction of T Cells and T Cell Precursors
    Amie Simmons, José Alberola‐Ila · 2015 · Methods in molecular biology
  7. P2X1 Selective Antagonists Block HIV-1 Infection through Inhibition of Envelope Conformation-Dependent Fusion
    Alexandra Y. Soare, Hagerah S. Malik, Natasha D. Durham, Tracey L. Freeman, Raymond A. Alvarez, Foramben Patel, Namita Satija, Chitra Upadhyay, Catarina E. Hioe, Benjamin K. Chen et al. · 2019 · Journal of Virology
  8. Head and neck tumor organoid biobank for modelling individual responses to radiation therapy according to the TP53/HPV status
    Christian Issing, Constantin Menche, Mara Romero Richter, Mohammed H. Mosa, Jens von der Grün, Maximilian Fleischmann, Philipp Thoenissen, Ria Winkelmann, Tahmineh Darvishi, Andreas German Loth et al. · 2025 · Journal of Experimental & Clinical Cancer Research
  9. A Video Protocol of Retroviral Infection in Primary Intestinal Organoid Culture
    Amanda Andersson-Rolf, Juergen Fink, Roxana C. Mustata, Bon-Kyoung Koo · 2014 · Journal of Visualized Experiments
  10. Modeling colorectal tumorigenesis using the organoids derived from conditionally immortalized mouse intestinal crypt cells (ciMICs)
    Xiaoxing Wu, Zhaoxia Li, Hongyu Zhang, Fang He, Min Qiao, Huaxiu Luo, Jing Zhang, Meng Zhang, Yukun Mao, William Wagstaff et al. · 2021 · Genes & Diseases
  11. Intestinal epithelial replacement by transplantation of cultured murine and human cells into the small intestine
    Hassan A. Khalil, Sung Noh Hong, Joshua D. Rouch, Andrew Scott, Yonghoon Cho, Jiafang Wang, Michael S. Lewis, Martı́n G. Martı́n, James Dunn, Matthias G. Stelzner · 2019 · PLoS ONE
  12. Organoids derived from digestive tract, liver, and pancreas
    An Tao Xu, Jin Lu Tong, Zhi Hua Ran · 2015 · Journal of Digestive Diseases
  13. Genetic Engineering of Primary Mouse Intestinal Organoids Using Magnetic Nanoparticle Transduction Viral Vectors for Frozen Sectioning
    Lingling Xian, Lionel Chia, Dan Georgess, Li Luo, Shuai Shuai, Andrew J. Ewald, Linda M S Resar · 2019 · Journal of Visualized Experiments
  14. Bioengineering methods for organoid systems
    Jad Saleh, Barbara Mercier, Wang Xi · 2021 · Biology of the Cell
  15. Use of conditional reprogramming cell, patient derived xenograft and organoid for drug screening for individualized prostate cancer therapy: Current and future perspectives (Review)
    Jessica Cao, Wing Hei Chan, Moses Chow · 2022 · International Journal of Oncology
  16. 3D intestinal organoids in metabolic research: virtual reality in a dish
    Anastasia Tsakmaki, Patricia Fonseca Pedro, Gavin A. Bewick · 2017 · Current Opinion in Pharmacology
  17. Epithelial and Mesenchymal Contribution to the Niche: A Safeguard for Intestinal Stem Cell Homeostasis
    Nicholas R. Smith, Paige S. Davies, Alain D. Silk, Melissa Hirose Wong · 2012 · Gastroenterology
  18. Organoids: A new in vitro model system for biomedical science and disease modelling and promising source for cell-based transplantation
    Bon‐Kyoung Koo, Meritxell Huch · 2016 · Developmental Biology
  19. Extracellular Vesicles Delivered by a Nanofiber‐Hydrogel Composite Enhance Healing In Vivo in a Model of Crohn's Disease Perianal Fistula
    Ling Li, Zhicheng Yao, Kevan J. Salimian, Jiayuan Kong, Atif Zaheer, Alyssa M. Parian, Susan L. Gearhart, Hai‐Quan Mao, Florin M. Selaru · 2024 · Advanced Healthcare Materials
  20. Targeting the gastrointestinal tract with viral vectors: state of the art and possible applications in research and therapy
    Roeland Buckinx, Jean‐Pierre Timmermans · 2016 · Histochemistry and Cell Biology
  21. Overexpression of the miR-17-92 cluster in colorectal adenoma organoids causes a carcinoma-like gene expression signature
    Sanne R. Martens‐de Kemp, Malgorzata A. Komor, Rosa Hegi, Anne S. Bolijn, Marianne Tijssen, Florence L. M. de Groen, Annekatrien C. T. M. Depla, Monique Esther van Leerdam, Gerrit A. Meijer, Remond J.A. Fijneman et al. · 2022 · Neoplasia
  22. Modelling adult stem cells and their niche in health and disease with epithelial organoids
    Lili Szabó, Anna C. Seubert, Kai Kretzschmar · 2022 · Seminars in Cell and Developmental Biology
  23. Intestinal Crypt Organoids as Experimental Models
    Sabina Lukovac, Guus Roeselers · 2015 · Springer eBooks
  24. Fabrication approaches for high-throughput and biomimetic disease modeling
    Mackenzie Grubb, Steven R. Caliari · 2021 · Acta Biomaterialia
  25. Cell heterogeneity and fate bistability drive tissue patterning during intestinal regeneration
    Cornelia Schwayer, Silvia Barbiero, David B. Brückner, Clara Baader, Nicole A. Repina, Oscar E. Diaz, Ludivine Challet Meylan, Véronique Kalck, Simon Suppinger, Qiutan Yang et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  26. IκBζ controls IL-17-triggered gene expression program in intestinal epithelial cells that restricts colonization of SFB and prevents Th17-associated pathologies
    Soh Yamazaki, Naohiro Inohara, Masaki Ohmuraya, Yousuke Tsuneoka, Hideo Yagita∥, Takaharu Katagiri, Takashi Nishina, Tetuo Mikami, Hiromasa Funato, Kimi Araki et al. · 2022 · Mucosal Immunology
  27. Evolution of organoid genetics
    Thomas M. Klompstra, Ki‐Jun Yoon, Bon‐Kyoung Koo · 2025 · European Journal of Cell Biology
  28. Small intestinal stem cells
    Stephanie L. King, Christopher M. Dekaney · 2013 · Current Opinion in Gastroenterology
  29. Generation and Analysis of Mouse Intestinal Tumors and Organoids Harboring APC and K-Ras Mutations
    Johan H. van Es, Hans C. Clevers · 2015 · Methods in molecular biology
  30. Activation of epithelial cells by the major kiwifruit allergen Act d 1 in human and mouse-derived intestinal model
    Andrijana Nešić, Annemarie Stam, Milena R. Cavic, Jean Paul ten Klooster, Raymond H. H. Pieters, Joost J. Smit, Marija Đ. Gavrović-Jankulović · 2019 · Journal of Functional Foods
  31. METTL3 restricts RIPK1-dependent cell death via the ATF3-cFLIP axis in the intestinal epithelium
    Meimei Huang, Xiaodan Wang, Mengxian Zhang, Yuan Liu, Ye‐Guang Chen · 2024 · Cell Regeneration
  32. Fluorescent labelling of intestinal epithelial cells reveals independent long-lived intestinal stem cells in a crypt
    Nobukatsu Horita, Kiichiro Tsuchiya, Ryohei Hayashi, Keita Fukushima, Shuji Hibiya, Masayoshi Fukuda, Yoshihito Kano, Tomohiro Mizutani, Yasuhiro Nemoto, Shiro Yui et al. · 2014 · Biochemical and Biophysical Research Communications
  33. Fragment-sequencing unveils local tissue microenvironments at single-cell resolution
    Kristina Handler, Karsten Bach, Costanza Borrelli, Salvatore Piscuoglio, Xenia Ficht, İlhan E. Acar, Andreas E. Moor · 2023 · Nature Communications
  34. Culturing intestinal stem cells: applications for colorectal cancer research
    Masayuki Fujii, Toshiro Sato · 2014 · Frontiers in Genetics
  35. Organoid Derivation and Orthotopic Xenotransplantation for Studying Human Intestinal Stem Cell Dynamics
    Shinya Sugimoto, Masayuki Fujii, Toshiro Sato · 2020 · Methods in molecular biology
  36. Next-Generation Modeling of Cancer Using Organoids
    Jillian R Love, Wouter R. Karthaus · 2023 · Cold Spring Harbor Perspectives in Medicine
  37. The critical role of BMP signaling in gastric epithelial cell differentiation revealed by organoids
    Fan Hong, Xiaodan Wang, Nanshan Zhong, Ze Zhang, Shibo Lin, Mengxian Zhang, Haonan Li, Yuan Liu, Yalong Wang, Lianzheng Zhao et al. · 2025 · Cell Regeneration
  38. Update on small intestinal stem cells
    Valentina Tesori · 2013 · World Journal of Gastroenterology
  39. Dissecting Functional, Structural, and Molecular Requirements for Serotonin Release from Mouse Enterochromaffin Cells
    Ahmed Shaaban, Frederike Maaß, Valentin Schwarze, Mari Lilith Lund, Sabine Beuermann, Michelle Chan, Christiane Harenberg, Gavin A. Bewick, Damien J. Keating, Fritz Benseler et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  40. Cytosolic DNA composition is determined by genomic instability mechanism and regulates dendritic cell-mediated anti-tumor immunity
    Shayla R. Mosley, Angie Chen, David N.W. Doell, Siwon Choi, Courtney Mowat, Felix Meier‐Stephenson, Vanessa Meier‐Stephenson, Kristi Baker · 2025 · Cell Reports
  41. Tracking HIV persistence across T cell lineages during early ART-treated HIV-1-infection using a reservoir-marking humanized mouse model
    Namita Satija, Foramben Patel, Gerrit Schmidt, Donald Doanman, Manav Kapoor, Annalena La Porte, Ying‐Chih Wang, Kenneth Law, Anthony M. Esposito, Kimaada Allette et al. · 2025 · Nature Communications
  42. Heterogeneity of Phase II Enzyme Ligands on Controlling the Progression of Human Gastric Cancer Organoids as Stem Cell Therapy Model
    Deng‐Chyang Wu, Chia‐Chen Ku, Jia-Bin Pan, Kenly Wuputra, Ya-Han Yang, Chung‐Jung Liu, Yi‐Chang Liu, Kohsuke Kato, Shigeo Saito, Ying‐Chu Lin et al. · 2023 · International Journal of Molecular Sciences
  43. Functional characterization and transcriptomic profiling of a spheroid-forming midgut cell line from Helicoverpa zea (Lepidoptera: Noctuidae)
    Elena Vorgia, Mantha Lamprousi, Shane Denecke, Kathrin Vogelsang, Sven Geibel, John G. VONTAS, Vassilis Douris · 2020 · Insect Biochemistry and Molecular Biology
  44. Efficient and simple genetic engineering of enteroids using mouse isolated crypts for investigating intestinal functions
    Shuya Ohira, Yuki Yokoi, Tokiyoshi Ayabe, Kiminori Nakamura · 2022 · Biochemical and Biophysical Research Communications
  45. Endocrine cancer organoids in basic and translational medical research
    Dong Chen, Zhulan Chen, Huihui Yang, Lei Zhang, Chenchen Hu, Zhuo Yang, Peng Li, Xi Su, Xiaoling Liu, Wei Wei et al. · 2025 · Science China Life Sciences
  46. Cross-Tissue Identification of Somatic Stem and Progenitor Cells Using a Single-Cell RNA-Sequencing Derived Gene Signature
    Petra Catalina Schwalie, Paloma Ordóñez‐Morán, Joerg Huelsken, Bart Deplancke · 2017 · Stem Cells
  47. Disease Severity Impairs Generation of Intestinal Organoid Cultures From Inflammatory Bowel Disease Patients
    Wei Yung Ding, Olivia M. Marx, Marc M. Mankarious, Walter A. Koltun, Gregory S. Yochum · 2023 · Journal of Surgical Research
  48. A High-throughput Cre-Lox Activated Viral Membrane Fusion Assay to Identify Inhibitors of HIV-1 Viral Membrane Fusion
    Anthony M. Esposito, Alexandra Y. Soare, Foramben Patel, Namita Satija, Benjamin K. Chen, Talia H. Swartz · 2018 · Journal of Visualized Experiments
  49. Scaffolds for intestinal tissue engineering
    Ninad S. Kanetkar, Adam K. Ekenseair · 2019 · Elsevier eBooks
  50. Cre-Recombinase Induces Apoptosis and Cell Death in Enterocyte Organoids
    Franziska Moll, Manuela Spaeth, Katrin Schröder · 2022 · Antioxidants
  51. An engineered tumor organoid model reveals cellular identity and signaling trajectories underlying SFPQ-TFE3 driven translocation RCC
    Maroussia M. P. Ganpat, Francisco Morales-Rodriguez, Nhung Pham, Philip Lijnzaad, Terezinha Maria de Souza, Sepide Derakhshan, Arianna Fumagalli, Peter J. Zeller, Aleksandra Balwierz, Dilara Ayyildiz et al. · 2025 · iScience
  52. Enhanced Apc adenoma formation after epithelial CUL4B deletion by recruitment of myeloid-derived suppressor cells
    Beibei Guo, Yawen Zheng, Yujia Fan, Yang� Yang, Yuxing Wang, Liping Qin, Yachun An, Xiaoran Xu, Xiyu Zhang, Gongping Sun et al. · 2024 · Neoplasia
  53. Optimized gene transduction in human lung organoids: A high-efficiency method for advanced research applications
    Jasmin Khateeb, Jady Liang, Yuchong Li, Thenuka Thanabalasingam, Julie Khang, Mirjana Jerkić, Giovanna Pellecchia, Bhooma Thiruvahindrapuram, Ya‐Wen Chen, Ori David Rotstein et al. · 2025 · Communications Biology
  54. Intestinal organoids
    Tamara Zietek, Eva Rath · 2018 · Elsevier eBooks
  55. Thiolated Thermoresponsive Polymer Scaffolds with Tunable Mucoadhesivity for Intestinal Applications
    Ninad S. Kanetkar, Adam K. Ekenseair · 2020 · Biomacromolecules
  56. Optimization of RNP-CRISPR for high-efficiency gene editing in mouse intestinal organoids
    Xiya Cao, Youyuan He, Haozhe Guo, Xiaoya Cao, Dan Zhang, Yuxuan Lai, Weihua Yang, Zixuan Ma, Xinghua Yu, Liren Wang et al. · 2026 · Molecular and Cellular Biochemistry
  57. Individualized Pooled CRISPR/Cas9 Screenings Identify CDK2 as a Druggable Vulnerability in a Canine Mammary Carcinoma Patient
    Marine Inglebert, Martina Dettwiler, Chang He, Enni Markkanen, Lennart Opitz, Arunasalam Naguleswaran, Sven Rottenberg · 2025 · Veterinary Sciences
  58. Lineage Tracing and Single-Cell RNA Sequencing Reveal a Common Transcriptional State in Breast Cancer Tumor–Initiating Cells Characterized by IFN/STAT1 Activity
    Eric P. Souto, Ping Gong, John David Landua, Ramakrishnan Rajaram Srinivasan, Abhinaya Ganesan, Lacey Elizabeth Dobrolecki, Stephen Connor Purdy, Xingxin Pan, Michael Zeosky, Anna Chung et al. · 2025 · Cancer Research
  59. Intestinal Epithelial Lgr5 + Stem Cell Niche and Organoids
    Nobuo Sasaki, Toshiro Sato, Hans C. Clevers · 2017 · Elsevier eBooks
  60. A functional sgRNA-CRISPR screening method for generating murine RET and NTRK1 rearranged oncogenes
    Laura Schubert, Anh T. Le, Trista K. Hinz, Andre Navarro, Sarah K. Nelson-Taylor, Raphael A. Nemenoff, Lynn E. Heasley, Robert Charles Doebele · 2023 · Biology Open
  61. The application of intestinal organoids and their co-culture systems in the study of gastrointestinal diseases
    Panida Sittipo, Yun Kyung Lee · 2022 · Organoid
  62. Isolating Rat Intestinal Explants for In Vitro Cultures
    Anjaney Kothari, Padmavathy Rajagopalan · 2019 · Current Protocols in Toxicology
  63. Reversal of lineage plasticity in RB1/TP53-deleted prostate cancer through FGFR and Janus kinase inhibition
    Wouter R. Karthaus, Joseph Minhow Chan, Manu N. Setty, Jillian R Love, Samir Zaidi, Zi-Ning Choo, Sitara Persad, Justin R. LaClair, Kayla E. Lawrence, Ojasvi Chaudhary et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  64. Mechanisms of resistance to VHL loss-induced genetic and pharmacological vulnerabilities
    Jianfeng Ge, Shoko Hirosue, Leticia Castillon, Saroor A. Patel, Ludovic Wesolowski, Anna Dyas, Cissy Yong, Sanne de Haan, Jarno Drost, Grant Duncan Stewart et al. · 2025 · EMBO Molecular Medicine
  65. Cytosolic DNA structures produced by mismatch repair deficiency coordinate anti-tumor immunity in colorectal cancer
    Shayla R. Mosley, Natalie Lapa, Afshin Namdar, Thomas E. Catley, Felix Meier‐Stephenson, Courtney Mowat, Pinzhang Gao, Xuejun Sun, Vanessa Meier‐Stephenson, Alice L. B. Pyne et al. · 2026 · Cell Reports
  66. Mapping self-associating chromatin hubs identifies Id proteins as key determinants of exhausted CD8+ T cell fate
    Wei Hu, Qing Chen, Shaoqi Zhu, Shengen Shawn Hu, Haibo Yu, Vanita Patel, Ying Wang, Vladimir P. Badovinac, Yi Zhang, Chongzhi Zang et al. · 2026 · Nature Immunology
  67. Protocol for transducing human primary epithelial prostate cells and patient-derived organoids with high efficiency
    Cynthia Jobin, Mario Harvey, Aurélie Lacouture, Cindy Weidmann, Bertrand Neveu, Frédéric Pouliot, Étienne Audet‐Walsh · 2024 · STAR Protocols
  68. Sphere-sequencing unveils local tissue microenvironments at single cell resolution
    Kristina Handler, Karsten Bach, Costanza Borrelli, Xenia Ficht, İlhan E. Acar, Andreas E. Moor · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  69. Acquired epithelial WNT secretion drives niche independence of developing gastric cancer
    Isaree Teriyapirom, Jihoon Kim, Heetak Lee, Sebastian R. Merker, Amanda Andersson-Rolf, Stephan René Jahn, Anne-Marlen Ada, Sangmin Kim, Joo Yeon Lim, Tim Schmäche et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  70. Lineage plasticity driven by GATA6 loss fuels colorectal cancer metastasis
    Saori Goto, Vikram Deshpande, Ömer H. Yilmaz, Norihiro Goto · 2026 · Cell stem cell
  71. Multiscale integration of tissue and chromatin context converts cell heterogeneity into stable intestinal patterning
    Cornelia Schwayer, Silvia Barbiero, David B. Brückner, Koen C. Oost, Clara Baader, Nicole A. Repina, Jinse Kim, Oscar E. Diaz, Isa Uccelli, Laura Capolupo et al. · 2026 · Cell
  72. Multitasking Paneth Cells in the Intestinal Stem Cell Niche
    M. Schewe, R. Fodde · 2018 · Advances in stem cells and their niches
  73. Establishment of Stable Knockdown of MACC1 Oncogene in Patient-Derived Ovarian Cancer Organoids
    Sophia Hierlmayer, Liliia Hladchenko, Juliane Reichenbach, Christoph Klein, Sven� Mahner, Fabian Trillsch, Mirjana Kessler, Anca Chelariu-Raicu · 2024 · Methods and Protocols
  74. Use of Organoids to Characterize Signaling Pathways in Cancer Initiation
    Christina Oatway, Calley L. Hirsch, Alex Gregorieff · 2018 · Methods in molecular biology
  75. Stem Cells and Tissue Renewal
    Johan H. van Es, Sina Bartfeld, Hans C. Clevers · 2015 · Yamada's Textbook of Gastroenterology
  76. Human Liver Organoids as a Patient-derived Model for HBV Infection and Cellular Response
    Chuan Kok Lim, Ornella Romeo, Andrew P Chilver, Bang Manh Tran, Dustin James Flanagan, Emily N. Kirby, James Breen, Elizabeth Vincan, Nadia Warner, Erin M. McCartney et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  77. Colorectal cancer: Current status of preclinical research
    Edward Agyarko, Benjamin Tagoe, Benedicta Obenewaa Dankyi, Benedicta Quaye, Mansa Fredua‐Agyeman, Seth Kwabena Amponsah · 2025 · Elsevier eBooks
  78. A modified system to promote stemness of mouse intestinal stem cells by activating Nrf2 and α2-adrenergic receptor signaling pathway
    Xingyu Zhou, Yang Li, Sentao Song, Xiaolei Yin · 2025 · Acta Biochimica et Biophysica Sinica
  79. Gastric cancer organoids and their convergence in engineering approaches
    SoEun Lim, So Hee Kim, Jeong Hye‐Jin, Steve Park, Bon‐Kyoung Koo, Ji‐Hyun Lee, Woojung Shin · 2026 · FEBS Letters
  80. The Use of High-Throughput Screening in Identifying Chemotherapeutic Agents for Gastric Cancer
    Horst Flotow · 2014 · Future Medicinal Chemistry
  81. Studying cancer drug resistance using BRCA-deficient mouse mammary tumor organoids
    Alexandra A. Duarte, Alexandra A. Duarte, Ewa Gogola, Norman Sachs, Marco Barazas, Stefano Annunziato, Julian R. de Ruiter, Arno Velds, Sohvi Blatter, Julia M. Houthuijzen et al. · 2017 · Protocol Exchange
  82. Generating Mini-Organs in Culture
    Hiroyuki Koike, Takanori Takebe · 2016 · Current Pathobiology Reports
  83. Induced pluripotent stem cells as models of human neurodevelopmental disorders
    Alexandre Jourdon, Jessica Mariani, Soraya Scuderi, Anahita Amiri, Feinan Wu, Eunice Y. Yuen, Alexej S. Abyzov, Flora Maria Vaccarino · 2020 · Elsevier eBooks
  84. Functional genetic dropout screens and in vivo validation of candidate therapeutic targets using mouse mammary tumoroids
    Mariana Paes Dias, Sven Rottenberg, Jos Jonkers · 2022 · STAR Protocols
  85. cGAS/STING and NLRP3 cooperatively activate CD8+ T cell-mediated anti-tumor immunity in colorectal cancer
    Courtney Mowat, Daniel Schiller, Kristi Baker · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  86. Cell surface proteomics of patient-derived malignant rhabdoid tumor organoids identifies ROBO1 as CAR T cell target for pediatric solid tumors
    Juliane L. Buhl, Jannet Koelewijn, Charlotte op ’t Hoog, Li Yang, Stijn De Munter, Victoria M. Cruz, D Chin, Baojie Zhang, Marliek van Hoesel, Nienke van Herk et al. · 2026 · Nature Communications
  87. Mechanisms of resistance to VHL loss-induced genetic and pharmacological vulnerabilities
    Jianfeng Ge, Shoko Hirosue, Saroor A. Patel, Ludovic Wesolowski, Anna Dyas, Cissy Yong, Leticia Castillon, Sanne de Haan, Jarno Drost, Grant Duncan Stewart et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  88. Inflammation and host-microbe signaling in the development and progression of colorectal carcinoma
    Yinghui Li · 2013 · Figshare
  89. Epigenomics of Intestinal Disease
    Daniel R. Kelly, Theresa Alenghat · 2016 · Elsevier eBooks
  90. Msh2-deficiency Affects the Differentiation and Proliferation of Small Intestinal Epithelial Cells
    Sofia Oke · 2016 · TSpace (University of Toronto)
  91. The Role of Rx in Embryonic Retinogenesis: Determining Genetic Influences on Optic Vesicle Formation and Photoreceptor Cell Fate
    Helen M. Rodgers · 2017
  92. Development of Small Intestinal Organoid Cultures for the Study of Enteric Pathogens
    Lisa Luu · 2018 · University of Liverpool
  93. Histone deacetylase inhibition by gut microbe-generated short chain fatty acids entrains intestinal epithelial circadian rhythms
    Deborah Luzader, Jibraan A. Fawad, Thomas J. Moutinho, Paul Mitchell, Kathleen Brown-Steinke, Jesse Y. Zhao, Andrew E. Rosselot, Craig A. McKinney, Christian I. Hong, C. James Chou et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  94. Constructing roadmaps towards functional cell types using organoids
    Joep Beumer · 2020
  95. Three-dimensional modelling of the human peri-implantation endometrium
    Thomas M. Rawlings · 2026 · Warwick Research Archive Portal (University of Warwick)
  96. Leveraging technological opportunities in cancer genomics
    Jose Espejo Valle-Inclán · 2021
  97. Engineered stem cells combine stem cell and gene therapy approaches to move intestine therapy from bench to bed
    Mahmoud Shaaban Mohamed, Mahmoud I. Elbadry, Chao‐Ling Yao · 2021 · Elsevier eBooks
  98. Epigenomics of intestinal disease
    Seika Hashimoto‐Hill, Daniel R. Kelly, Theresa Alenghat · 2021 · Elsevier eBooks
  99. Blockade of IL-6 inhibits tumor immune evasion and improves anti–PD-1 immunotherapy
    Wenhui Ma, Wenyi Li, Zhaokun Wu, Chaoting Zhang, Mingzhen Cheng, Yuehong Chen, Yini Zou, Kejun Li, Simin Lin, Wenjun Xiong et al. · 2022 · Research Square
  100. Faculty Opinions recommendation of FOXA1 mutations alter pioneering activity, differentiation and prostate cancer phenotypes.
    Andrew D Sharrocks · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature