Controlled gene expression in primary Lgr5 organoid cultures
Koo, Bon-Kyoung, Stange, Daniel E, Sato, Toshiro, Karthaus, Wouter, Farin, Henner F, Huch, Meritxell, van Es, Johan H, Clevers, Hans·2012·Nature Methods
Cited by (322)
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- A Rapid, Functional sgRNA Screening Method for Generating Murine RET and NTRK1 Fusion OncogenesLaura Schubert, Anh T. Le, Trista K. Hinz, Andre Navarro, Sarah K. Nelson-Taylor, Raphael A. Nemenoff, Lynn E. Heasley, Robert Charles Doebele · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- Deletion of CUL4B in gut epithelium promotes ApcMin/+ adenoma formation by impacting the microenvironmentBeibei Guo, Yawen Zheng, Yujia Fan, Yang Yang, Yuxing Wang, Liping Qin, Yachun An, Xiaoran Xu, Xiyu Zhang, Gongping Sun et al. · 2023 · Research Square
- An engineered tumor organoid model reveals cellular identity and signaling trajectories underlying translocation RCCMaroussia M. P. Ganpat, Francisco Morales-Rodriguez, Nhung Pham, Philip Lijnzaad, Terezinha Maria de Souza, Sepide Derakshan, Arianna Fumagalli, Peter J. Zeller, Aleksandra Balwierz, Dilara Ayyildiz et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- The interferon/STAT1 signaling axis is a common feature of tumor-initiating cells in breast cancerEric P. Souto, Ping Gong, John David Landua, R. Rajaram Srinivasan, Abhinaya Ganesan, Lacey Elizabeth Dobrolecki, Stephen C. Purdy, Xingxin Pan, Michael Zeosky, Anna Chung et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- Gastric organoids: Rise of a latecomerJiachen Yang, Yu-Hang Zhang, Bing Hu · 2024 · World Chinese Journal of Digestology
- Additional file 4 of Pharmacologic inhibition of IL11/STAT3 signaling increases MHC-I expression and T cell infiltrationWenjun Xiong, Yuehong Chen, Chaoting Zhang, Li, Jin, Haipeng Huang, Yu Zhu, Guangxu Deng, Junhong Cheng, Yixiong Lin, Zhimin Shi et al. · 2023 · Figshare
- Additional file 3 of Pharmacologic inhibition of IL11/STAT3 signaling increases MHC-I expression and T cell infiltrationWenjun Xiong, Yuehong Chen, Chaoting Zhang, Li, Jin, Haipeng Huang, Yu Zhu, Guangxu Deng, Junhong Cheng, Yixiong Lin, Zhimin Shi et al. · 2023 · Figshare
- Development of an intraventricular Adeno-Associated Virus-based labelling strategy for glioblastoma cells nested in the subventricular zoneArnaud Lombard, Damla Isci, Gilles Reuter, Emmanuel Di Valentin, Alexandre Hego, Didier Martin, Bernard Rogister, Virginie Neirinckx · 2024 · Neuro-Oncology Advances
- Genetic Manipulation in Organoid Models and Their Applications in Central Nervous System PathologiesAladin Rustamov, Melike Kocahasan, Baseerat Rumman, Reza Rahbarghazi, Emel Sokullu · 2025 · Molecular Neurobiology
- Additional file 2 of Pharmacologic inhibition of IL11/STAT3 signaling increases MHC-I expression and T cell infiltrationXiong, Wenjun, Chen, Yuehong, Chaoting Zhang, Li, Jin, Huang, Haipeng, Zhu, Yu, Deng, Guangxu, Junhong Cheng, Yixiong Lin, Shi, Zhimin et al. · 2023 · Figshare
- Additional file 1 of Pharmacologic inhibition of IL11/STAT3 signaling increases MHC-I expression and T cell infiltrationXiong, Wenjun, Chen, Yuehong, Chaoting Zhang, Li, Jin, Huang, Haipeng, Zhu, Yu, Deng, Guangxu, Junhong Cheng, Yixiong Lin, Shi, Zhimin et al. · 2023 · Figshare
- Organoid Perturbations as Tools to Explore Cellular Function and PlasticityKatharina Eva Kohl, Georg A. Busslinger · 2026 · Annual Review of Genomics and Human Genetics
- A Pleiotropic Role of the SWI/SNF Complex in Cancer – Insights From Two Tumor Types : Small Cell Carcinoma of the Ovary, Hypercalcemic Type and Prostatic CarcinomaJoanna Cyrta · 2020
- Mechanical modulation of morphogenesis in the intestinal epithelium : from stem cell niche to terminal differentiationJad Saleh · 2021 · theses.fr (ABES)
- BLM regulates MALT1-driven NF-κB signalling and is targetable in B-cell malignanciesRitu Agrawal, Supratim Ghosh, Nitin Kumar, Chetana Mukherjee, Vandana Sharma, Rimpy Arun, Riya Deb, Sumanta Sarkar, Savita, Dilip Kumar et al. · 2026 · Cell Death and Disease
- Tumor Microenvironment Modulates Lineage Plasticity in Lung Squamous Cell CarcinomaY Fujibayashi, Hiroyuki Ogawa, Qixuan Li, Roya Navab, T. Koga, Yoshiaki Inoue, Nhu‐An Pham, Hironori Hinokuma, Nicholas Bernards, Tadashi Sakane et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- Enteroid culture and its impact on stem cell and cancer researchHoffman, Andrew · 2014
- RasGRP1 promotes efficient intestinal tuft cell differentiationLauren A. Shechtman, Philippe Depeille, Eric Smith, Hong-Erh Liang, Tammie S. Y. Tam, Annabelle Duflock, Victor S. Cortez, Claire E. O’Leary, Alan Shen, Wouter Bos et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)