Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture
Paşca, Anca M, Sloan, Steven A, Clarke, Laura E, Tian, Yuan, Makinson, Christopher D, Huber, Nina, Kim, Chul Hoon, Park, Jin-Young +7 more·2015·Nature Methods
Cited by (1,004)
Items 701–800 of 1,004
- Neuronal hyperexcitability and ion channel dysfunction in CDKL5-deficiency patient iPSC-derived cortical organoidsWei Wu, Hang Yao, Priscilla Davidson Negraes, Juan Wang, Cleber A. Trujillo, Janaína Sena de Souza, Alysson Renato Muotri, Gabriel George Haddad · 2022 · Neurobiology of Disease
- Brain Regional Identity and Cell Type Specificity Landscape of Human Cortical Organoid ModelsManuela Magni, Beatrice Bossi, Paola Conforti, Maura Galimberti, Fabio Dezi, Tiziana Lischetti, Xiaoli He, RogerA Barker, Chiara Zuccato, Ira Espuny-Camacho et al. · 2022 · International Journal of Molecular Sciences
- Brain organoids: Establishment and applicationHao Chen, Xin Jin, Tie Li, Zhuang Ye · 2022 · Frontiers in Cell and Developmental Biology
- Accounting for cis-regulatory constraint prioritizes genes likely to affect species-specific traitsAlexander L. Starr, David Gokhman, Hunter B. Fraser · 2023 · Genome biology
- Novel model of cortical–meningeal organoid co-culture system improves human cortical brain organoid cytoarchitectureE. Jalilian, S. Shin · 2023 · Scientific Reports
- Microinstrumentation for Brain OrganoidsDevan Patel, Saniya Shetty, Chris Acha, Itzy E. Morales Pantoja, Alice Zhao, Derosh George, David H. Gracias · 2024 · Advanced Healthcare Materials
- Guidelines for Manufacturing and Application of Organoids: BrainTaehwan Kwak, Si-Hyung Park, Siyoung Lee, Yujeong Shin, Ki‐Jun Yoon, Seung‐Woo Cho, Jong‐Chan Park, Seung-Ho Yang, Heeyeong Cho, Heh‐In Im et al. · 2024 · International Journal of Stem Cells
- Brain organoids: A new tool for modelling of neurodevelopmental disordersYirizhati Aili, Nuersimanguli Maimaitiming, Zengliang Wang, Yongxin Wang · 2024 · Journal of Cellular and Molecular Medicine
- In vitro and in silico Models to Study Mosquito-Borne Flavivirus Neuropathogenesis, Prevention, and TreatmentMegan Chesnut, Laura Sofia Munoz-Arcos, Georgina Harris, Dana M. Freeman, Lúcio Gama, Carlos A. Pardo, David Pamies · 2019 · Frontiers in Cellular and Infection Microbiology
- Modeling Down syndrome in cells: From stem cells to organoidsGillian Gough, Niamh Louise O’Brien, Ivan Alić, Pollyanna Agnes Goh, Yee Jie Yeap, Jürgen Groet, Dean Nižetić, Aoife Murray · 2019 · Progress in brain research
- Human Induced Pluripotent Stem Cell Models of Neurodegenerative Disorders for Studying the Biomedical Implications of AutophagyElena Seranova, Adina Maria Palhegyi, Surbhi Verma, Simona Dimova, Rachel Lasry, Moriyah Naama, Congxin Sun, Timothy Geoffrey Barrett, Tatiana Rosado Rosenstock, Dhiraj Kumar et al. · 2020 · Journal of Molecular Biology
- Human iPSC-Derived Glia as a Tool for Neuropsychiatric Research and Drug DevelopmentJohanna Heider, Sabrina Vogel, Hansjürgen Volkmer, Ricarda Breitmeyer · 2021 · International Journal of Molecular Sciences
- Stem and Progenitor Cell-Derived Astroglia Therapies for Neurological DiseasesChen Chen, Albert Chan, Wen Han, Seung‐Hyuk Chung, Wenbin Deng, Peng Jiang · 2015 · Trends in Molecular Medicine
- Using hiPSCs to model neuropsychiatric copy number variations (CNVs) has potential to reveal underlying disease mechanismsFlaherty, Erin K., Brennand, Kristen J. · 2017 · Brain Research
- Parechovirus infection in human brain organoids: host innate inflammatory response and not neuro-infectivity correlates to neurologic diseasePamela E. Capendale, Inés García-Rodríguez, Anoop T. Ambikan, Lance Mulder, Josse A. Depla, Eline Freeze, Gerrit Koen, Carlemi Calitz, Vikas Sood, Renata Vieira de Sá et al. · 2024 · Nature Communications
- Brain organoid models for studying the function of iPSC-derived microglia in neurodegeneration and brain tumoursAngélica María Sabogal-Guáqueta, Teresa Mitchell-Garcia, Jasmijn Hunneman, Daniëlle C. Voshart, Arun Thiruvalluvan, Floris Foijer, Frank A.E. Kruyt, Marina Trombetta-Lima, Bart J. L. Eggen, Erik Boddeke et al. · 2024 · Neurobiology of Disease
- APOE4 impacts cortical neurodevelopment and alters network formation in human brain organoidsKarina K. Meyer-Acosta, Eva Díaz‐Guerra, Parul Varma, Adyasha Aruk, Sara Mirsadeghi, Aranis Muniz Perez, Yousef Rafati, Ali Hosseini, Vanesa Nieto‐Estévez, Michèle Giugliano et al. · 2025 · Stem Cell Reports
- Is Alzheimer’s Also a Stem Cell Disease? – The Zebrafish PerspectiveÇağhan Kızıl, Prabesh Bhattarai · 2018 · Frontiers in Cell and Developmental Biology
- Nanomedicine against Alzheimer’s and Parkinson’s DiseaseAnkit Tandon, Sangh Jyoti Singh, Rajnish Kumar Chaturvedi · 2020 · Current Pharmaceutical Design
- Biofidelic dynamic compression of human cortical spheroids reproduces neurotrauma phenotypesAaron R. Shoemaker, Ian E. Jones, Kira Jeffris, Gina Gabrielli, Alyssa G. Togliatti, Rajeswari Pichika, Eric Martin, Evangelos Kiskinis, Colin K. Franz, John D. Finan · 2021 · Disease Models & Mechanisms
- The Evolution of Complex Muscle Cell In Vitro Models to Study Pathomechanisms and Drug Development of Neuromuscular DiseaseJana Zschüntzsch, Stefanie Meyer, Mina Shahriyari, Karsten Kummer, Matthias Schmidt, Susann Kummer, Malte Tiburcy · 2022 · Cells
- Establishment and characterization of human pluripotent stem cells-derived brain organoids to model cerebellar diseasesJoão Brás, Daniel Henriques, Ricardo Moreira, Magda M. Santana, Rita Silva-Pedrosa, Diana Adão, Sandra Bráz, Ana Rita Álvaro, Luís Pereira de Almeida, Liliana S. Mendonça · 2022 · Scientific Reports
- Transition from Animal-Based to Human Induced Pluripotent Stem Cells (iPSCs)-Based Models of Neurodevelopmental Disorders: Opportunities and ChallengesSara R. Guerreiro, Patrı́cia Maciel · 2023 · Cells
- Host circuit engagement of human cortical organoids transplanted in rodentsKevin W. Kelley, Omer Revah, Felicity Gore, Konstantin Kaganovsky, Xiaoyu Chen, Karl A. Deisseroth, Sergiu P. Pașca · 2024 · Nature Protocols
- Progress and potential of brain organoids in epilepsy researchRachel Brown, Alexa Rabeling, Mubeen Goolam · 2024 · Stem Cell Research & Therapy
- Concise Review: Induced Pluripotent Stem Cell Models for Neuropsychiatric DiseasesAbidemi A. Adegbola, Luke A. D. Bury, Chen Sheng Fu, Meixiang Zhang, Anthony J. Wynshaw-Boris · 2017 · Stem Cells Translational Medicine
- Default Patterning Produces Pan-cortical Glutamatergic and CGE/LGE-like GABAergic Neurons from Human Pluripotent Stem CellsCrina M. Floruta, Ruofei Du, Huining Kang, Jason L. Stein, Jason Porter Weick · 2017 · Stem Cell Reports
- Prospects for Modeling Abnormal Neuronal Function in Schizophrenia Using Human Induced Pluripotent Stem CellsIya Prytkova, Kristen Brennand · 2017 · Frontiers in Cellular Neuroscience
- Brain Organoids: Tiny Mirrors of Human Neurodevelopment and Neurological DisordersAnuradha Yadav, Brashket Seth, Rajnish Kumar Chaturvedi · 2020 · The Neuroscientist
- Impaired p53-Mediated DNA Damage Response Contributes to Microcephaly in Nijmegen Breakage Syndrome Patient-Derived Cerebral OrganoidsSoraia Martins, Lars Erichsen, Angeliki Datsi, Wasco Wruck, Wolfgang Goering, Eleftheria Chatzantonaki, Vanessa Cristina Meira de Amorim, Andrea Rossi, Krystyńa Chrzańowska, James Adjaye · 2022 · Cells
- Integrated manufacturing platform for cortical organoids reveals early phosphatase and prefoldin dysregulation in MAPT V337M neuronsTaylor B. Bertucci, Kathryn R. Bowles, Steven Lotz, Shiraz Bheda, Le Qi, Farhad Farjood, Katherine Whitton, Susan K. Goderie, Susan M. Borden, Amelia Rossi et al. · 2026 · npj Dementia
- Recent advances in regenerative medicineKuldeep Rajpoot, Maliheh Safavi, Nagaraja Sreeharsha, Rakesh Kumar Tekade · 2020 · Elsevier eBooks
- Differentiating visceral sensory ganglion organoids from induced pluripotent stem cellsKyusik Ahn, Hwee-Seon Park, Sieun Choi, Ho-Jeong Lee, Hyunjung Choi, Seok Beom Hong, Jihui Han, Jong Won Han, Jin-Chul Ahn, Jae‐Hoon Song et al. · 2024 · Nature Methods
- Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative MedicineRuiqi Huang, Feng Gao, Liqun Yu, Haokun Chen, Rongrong Zhu · 2025 · Advanced Science
- iPSC toolbox for understanding and repairing disrupted brain circuits in autismSimone Chiola, Nicolas Ulrich Edgar, Aleksandr Shcheglovitov · 2021 · Molecular Psychiatry
- Effects of the Selective Serotonin Reuptake Inhibitor Fluoxetine on Developing Neural Circuits in a Model of the Human Fetal CortexKinsley M. Tate, Brenna Kirk, Alisia Tseng, Abigail E. Ulffers, Karen Litwa · 2021 · International Journal of Molecular Sciences
- Cortical Organoids to Model MicrocephalySarah Farcy, Alexandra Albert, Pierre Gressèns, Alexandre D. Baffet, Vincent El Ghouzzi · 2022 · Cells
- Probing the molecular and cellular pathological mechanisms of schizophrenia using human induced pluripotent stem cell modelsRebecca Sebastian, Yoonjae Song, ChangHui Pak · 2022 · Schizophrenia Research
- Neuron(s)-on-a-Chip: A Review of the Design and Use of Microfluidic Systems for Neural Tissue CultureDavid Choy Buentello, Mariana García-Corral, Grissel Trujillo‐de Santiago, Mario Moisés Álvarez · 2022 · IEEE Reviews in Biomedical Engineering
- A 3D human co-culture to model neuron-astrocyte interactions in tauopathiesKevin Llewelyn Batenburg, Claudia Sestito, Paulien Cornelissen‐Steijger, Jan R.T. van Weering, Leo Price, Vivi Majella Heine, Wiep Scheper · 2023 · Biological Procedures Online
- Neurorestorative Approaches for Ischemic StrokePaulina Michór, Lydia Renardson, Shen Li, Johannes Boltze · 2024 · Neuroscience
- Human Cortical Neuron Generation Using Cell Reprogramming: A Review of Recent AdvancesAmy McCaughey‐Chapman, Bronwen J. Connor · 2018 · Stem Cells and Development
- Single-cell genomic analysis of human cerebral organoidsSabina Kanton, Barbara Treutlein, J. Gray Camp · 2020 · Methods in cell biology
- A multiparametric calcium signal screening platform using iPSC-derived cortical neural spheroids.Molly E. Boutin, Caroline E. Strong, Brittney Van Hese, Xin Hu, Zina Itkin, Yu‐Chi Chen, Andrew S. LaCroix, Ryan Gordon, Oivin M. Guicherit, Cassiano Carromeu et al. · 2022 · SLAS DISCOVERY
- Establishment and Validation of a Model for Fetal Neural Ischemia Using Necrotic Core-Free Human Spinal Cord OrganoidsAeri Shin, Jae Ryun Ryu, Byung Gon Kim, Woong Sun · 2023 · Stem Cells Translational Medicine
- Modeling neurodevelopment in a dish with pluripotent stem cellsKent Imaizumi, Hideyuki Okano · 2020 · Development Growth & Differentiation
- The Emerging Role of Neuronal Organoid Models in Drug Discovery: Potential Applications and Hurdles to ImplementationLaura A. Struzyna, Marla L. Watt · 2021 · Molecular Pharmacology
- Resolving cell state in iPSC-derived human neural samples with multiplexed fluorescence imagingMartin L. Tomov, Alison O’Neil, Hamdah Shafqat Abbasi, Beth A. Cimini, Anne Elizabeth Carpenter, Lee L. Rubin, Mark Bathe · 2021 · Communications Biology
- Advances in neural organoid systems and their application in neurotoxicity testing of environmental chemicalsYuanyuan Zheng, Fangrong Zhang, Shengmin Xu, Lijun Wu · 2021 · Genes and Environment
- Brain and Retinal Organoids for Disease Modeling: The Importance of In Vitro Blood–Brain and Retinal Barriers StudiesIlenia Martinelli, Seyed Khosrow Tayebati, Daniele Tomassoni, Giulio Nittari, Proshanta Roy, Francesco Amenta · 2022 · Cells
- A simplified protocol for the generation of cortical brain organoidsKristel N. Eigenhuis, Hedda B. Somsen, Mark van der Kroeg, Hilde Smeenk, Anne L. Korporaal, Steven A. Kushner, Femke M. S. de Vrij, Debbie L. C. van den Berg · 2023 · Frontiers in Cellular Neuroscience
- Modeling early human cortical development and evaluating neurotoxicity with a forebrain organoid systemYuanqing Cao, Daiyu Hu, Chenglin Cai, Min Zhou, Peibing Dai, Qiong Lai, Ling Zhang, Yantao Fan, Zhengliang Gao · 2023 · Environmental Pollution
- Constructing human neural circuits in living systems by transplantationSergiu P. Pașca · 2024 · Cell
- Non‐Invasive Quality Control of Organoid Cultures Using Mesofluidic CSTR Bioreactors and High‐Content ImagingSeleipiri Charles, Emily Jackson, Gongchen Sun, Ying Zhou, Benjamin Siciliano, Weibo Niu, Haejun Han, Arina A. Nikitina, Melissa Lambeth Kemp, Zhexing Wen et al. · 2024 · Advanced Materials Technologies
- Genomic predictors of radiation response: recent progress towards personalized radiotherapy for brain metastasesPaul M. Harary, Sanjeeth Rajaram, Maggie S. Chen, Yusuke S. Hori, David Jaehyun Park, Steven Daniel Chang · 2024 · Cell Death Discovery
- Focus on Causality in ESC/iPSC-Based Modeling of Psychiatric DisordersAnke Hoffmann, Michael J. Ziller, Dietmar Spengler · 2020 · Cells
- Human organoids to model the developing human neocortex in health and diseaseKhakipoor, Shokoufeh, Crouch, Elizabeth E., Mayer, Simone · 2020 · Brain Research
- In vitro modeling for inherited neurological diseases using induced pluripotent stem cells: from 2D to organoidKi Hong Nam, Sang Ah Yi, Hyun Ji Jang, Jeung‐Whan Han, Jaecheol Lee · 2020 · Archives of Pharmacal Research
- Neuronal Differentiation of Induced Pluripotent Stem Cells from Schizophrenia Patients in Two-Dimensional and in Three-Dimensional Cultures Reveals Increased Expression of the Kv4.2 Subunit DPP6 That Contributes to Decreased Neuronal ActivityMaximilian Naujock, Anna Speidel, Sandra Elisabeth Fischer, Valeria Kizner, Cornelia Dorner‐Ciossek, Frank Gillardon · 2020 · Stem Cells and Development
- Synaptic Hyaluronan Synthesis and CD44-Mediated Signaling Coordinate Neural Circuit DevelopmentEmily S. Wilson, Karen Litwa · 2021 · Cells
- Generation of human midbrain organoids from induced pluripotent stem cellsNguyen‐Vi Mohamed, Meghna Mathur, Ronan V. da Silva, Rhalena A. Thomas, Paula Lépine, Lenore K. Beitel, Edward A. Fon, Thomas M. Durcan · 2021 · MNI Open Research
- Engineering microsystems to recapitulate brain physiology on a chipKenneth Ndyabawe, William S. Kisaalita · 2019 · Drug Discovery Today
- Modeling Williams syndrome with induced pluripotent stem cellsThanathom Chailangkarn, Alysson Renato Muotri · 2017 · Neurogenesis
- Challenges in Physiological Phenotyping of hiPSC-Derived Neurons: From 2D Cultures to 3D Brain OrganoidsPedro Mateos‐Aparicio, Sabina A. Bello, Antonio Rodríguez Moreno · 2020 · Frontiers in Cell and Developmental Biology
- Spontaneous spheroids from alveolar bone-derived mesenchymal stromal cells maintain pluripotency of stem cells by regulating hypoxia-inducible factorsNi Li, Xiaofeng Dai, Fei Yang, Yang Sun, Xingwen Wu, Qianrong Zhou, Kai Chen, Jian Sun, Wei Bi, Le Shi et al. · 2023 · Biological Research
- The exon junction complex component EIF4A3 is essential for mouse and human cortical progenitor mitosis and neurogenesisBianca M. Lupan, Rachel A. Solecki, Camila Manso Musso, Fernando C. Alsina, Debra L. Silver · 2023 · Development
- Generation of mouse hippocampal brain organoids from primary embryonic neural stem cellsFrancesca Ciarpella, Raluca Georgiana Zamfir, Alessandra Campanelli, Giulia Pedrotti, Marzia Di Chio, Emanuela Bottani, Ilaria Decimo · 2023 · STAR Protocols
- Highly reproducible and cost-effective one-pot organoid differentiation using a novel platform based on PF-127 triggered spheroid assemblyXiaoshan Zhang, Gang Xie, Honghao Ma, Shuangjin Ding, Yixia Wu, Yuan Fei, Qiang Cheng, Yanyi Huang, Yangming Wang · 2023 · Biofabrication
- Neuroimmune mechanisms in autism etiology - untangling a complex problem using human cellular modelsJanay M. Vacharasin, Joseph A Ward, Mikayla M. McCord, Kaitlin Cox, Jaime Imitola, Sofia B. Lizarraga · 2024 · Oxford Open Neuroscience
- Chronic Opioid Treatment Arrests Neurodevelopment and Alters Synaptic Activity in Human Midbrain OrganoidsHye Sung Kim, Yang Xiao, Xuejing Chen, Siyu He, Jongwon Im, Moshe J. Willner, Michael O. Finlayson, Cong Xu, Huixiang Zhu, Se Joon Choi et al. · 2024 · Advanced Science
- Identity and Maturity of iPSC-Derived Oligodendrocytes in 2D and Organoid SystemsE. Zeldich, S. Rajkumar · 2024 · Cells
- Applications of 3D organoids in toxicological studies: a comprehensive analysis based on bibliometrics and advances in toxicological mechanismsHaitao Yang, Shuyan Niu, Meng-Hao Guo, Yuying Xue · 2024 · Archives of Toxicology
- The use of human neurons for novel drug discovery in dementia researchMariana Vargas‐Caballero, Sandrine Willaime‐Morawek, Diego Gómez‐Nicola, Victor Hugh Perry, Diederik Olivier Bulters, Amritpal K. Mudher · 2016 · Expert Opinion on Drug Discovery
- NIH workshop report on the trans-agency blood–brain interface workshop 2016: exploring key challenges and opportunities associated with the blood, brain and their interfaceMargaret J. Ochocinska, Berislav V. Zloković, Peter C. Searson, A. Tamara Crowder, Richard P. Kraig, Julia Y. Ljubimova, Todd G. Mainprize, William A. Banks, Ronald Q. Warren, Andrei Kindzelski et al. · 2017 · Fluids and Barriers of the CNS
- Application of human pluripotent stem cells and pluripotent stem cell-derived cellular models for assessing drug toxicityÁgota Apáti, Nóra Varga, Tünde Berecz, Zsuzsa Erdei, László Homolya, Balázs Sarkadi · 2018 · Expert Opinion on Drug Metabolism & Toxicology
- Decoding epigenetic cell signaling in neuronal differentiationMariana Sousa Vieira, Vânia A. M. Goulart, Ricardo Cambraia Parreira, Onésia Cristina Oliveira‐Lima, Talita Glaser, Yahaira Naaldijk, Alejandra I. Ferrer, Vibha Harindra Savanur, Paola Alicea Reyes, Oleta A. Sandiford et al. · 2019 · Seminars in Cell and Developmental Biology
- Collagen Based Multicomponent Interpenetrating Networks as Promising Scaffolds for 3D Culture of Human Neural Stem Cells, Human Astrocytes, and Human MicrogliaRachel Van Drunen, Andrea C. Jimenez‐Vergara, Erin H. Tsai, Rachel Tchen, Tyler Cagle, Anne B. Agee, James T. Roberts, Jennifer M. Steele, Dany J. Munoz‐Pinto · 2019 · ACS Applied Bio Materials
- Review of functional in vitro models of the blood-cerebrospinal fluid barrier in leukaemia researchUlrike Erb, Christian Schwerk, Horst Schroten, Michael Karremann · 2019 · Journal of Neuroscience Methods
- Building a Human Brain for ResearchMainá Bitar, Guy Barry · 2020 · Frontiers in Molecular Neuroscience
- SpikeOnChip : A Custom Embedded Platform for Neuronal Activity Recording and AnalysisRick Wertenbroek, Yann Thoma, Flavio Maurizio Mor, Sara Grassi, Marc Olivier Heuschkel, Adrien Roux, Luc Stoppini · 2021 · IEEE Transactions on Biomedical Circuits and Systems
- Protocol for the Differentiation of Human Induced Pluripotent Stem Cells into Mixed Cultures of Neurons and Glia for Neurotoxicity TestingFrancesca Pistollato, David Canovas-Jorda, Dimitra Zagoura, Anna Price · 2017 · Journal of Visualized Experiments
- Generation of Urine-Derived Induced Pluripotent Stem Cells and Cerebral Organoids for Modeling Down SyndromeAndré Luíz Teles e Silva, Bruno Yukio Yokota-Moreno, Andrea Laurato Sertie, Bruna Lancia Zampieri · 2023 · Stem Cell Reviews and Reports
- TMEM161B modulates radial glial scaffolding in neocortical developmentLu Wang, Caleb S. Heffner, Keng Ioi Vong, Chelsea Barrows, Yoo-Jin Jiny Ha, Sangmoon Lee, Pablo Lara-González, Ishani Jhamb, Dennis van der Meer, Robert J. Loughnan et al. · 2023 · Proceedings of the National Academy of Sciences
- Perspective: The role of mechanobiology in the etiology of brain metastasisKandice Tanner · 2018 · APL Bioengineering
- The effect of rho kinase inhibition on morphological and electrophysiological maturity in iPSC-derived neuronsLise J. Harbom, Taylor Rudisill, Nadine Michel, Karen Litwa, Mark P. Beenhakker, Michael J. McConnell · 2018 · Cell and Tissue Research
- The abiding relevance of mouse models of rare mutations to psychiatric neuroscience and therapeuticsJoseph A. Gogos, Gregg W. Crabtree, Anastasia Diamantopoulou · 2019 · Schizophrenia Research
- From iPS Cells to Rodents and Nonhuman Primates: Filling Gaps in Modeling Parkinson's DiseaseTiago F. Outeiro, Peter Heutink, Erwan Bézard, Maria Angela Cenci · 2020 · Movement Disorders
- Brain-on-a-Chip Device for Modeling Multiregional NetworksKenneth Ndyabawe, Michael J. Cipriano, Wujun Zhao, Mark A. Haidekker, Kun Yao, Leidong Mao, William S. Kisaalita · 2020 · ACS Biomaterials Science & Engineering
- Application of a high-density microelectrode array assay using a 3D human iPSC-derived brain microphysiological system model for in vitro neurotoxicity screening of environmental compoundsKelly E. Carstens, Elena Gronskaya, David Jäckel, Jessica Bertoli, Kelvin Ramirez Cuevas, Julien Dorier, Shan Wang, David López-Rodríguez, Timothy J. Shafer, Marie‐Gabrielle Zurich et al. · 2025 · Archives of Toxicology
- Advanced Biomanufacturing Technologies for Micro-physiological SystemsMin Kyeong Kim, Jungbin Yoon, Dohui Kim, Jae‐Seok Kim, Jae-Seok Kim, Gyugang Go, Junhyeok Song, Seunghun Son, Kyungdeok Park, Donghan Lee et al. · 2025 · International Journal of Precision Engineering and Manufacturing
- Modeling neurodevelopmental and psychiatric diseases with human iPSCsZhexing Wen · 2017 · Journal of Neuroscience Research
- Analysis of Aβ-induced neurotoxicity and microglial responses in simple two- and three-dimensional human iPSC-derived cortical culture systemsMayuko Takata, Kaneyasu Nishimura, Koki Harada, Ryota Iwasaki, Momona Ando, Shiho Yamada, Florent Ginhoux, Kazuyuki Takata · 2023 · Tissue and Cell
- The Generation of Human iPSC Lines from Three Individuals with Dravet Syndrome and Characterization of Neural Differentiation Markers in iPSC-Derived Ventral Forebrain Organoid ModelV. Zayat, Zuzanna Kuczynska, Michal Liput, Erkan Metin, Sylwia Rzońca-Niewczas, M. Smyk, T. Mazurczak, Alicja Goszczańska-Ciuchta, Paweł Leszczyński, D. Hoffman-Zacharska et al. · 2023 · Cells
- Human‐induced pluripotent stem cell‐derived cerebral organoid of leukoencephalopathy with vanishing white matterJiong Deng, Jie Zhang, Kai Gao, Ling Zhou, Yuwu Jiang, Jingmin Wang, Ye Wu · 2023 · CNS Neuroscience & Therapeutics
- Biological and structural phenotypes associated with neurodevelopmental outcomes in congenital heart diseaseCharlotte E. Verrall, Shrujna Patel, Leksi Travitz, Jason H. Tchieu, Russell Clive Dale, Nadine Angele Kasparian, David Scott Winlaw, Gillian M. Blue · 2023 · Translational Pediatrics
- Thermodynamic and kinetic approaches for drug discovery to target protein misfolding and aggregationMichele Vendruscolo · 2023 · Expert Opinion on Drug Discovery
- Transcriptional Dysregulation and Impaired Neuronal Activity in FMR1 Knock-Out and Fragile X Patients’ iPSC-Derived ModelsGilles Maussion, Cecilia Rocha, Narges Abdian, Dimitri Yang, J Turk, Dulce Carrillo Valenzuela, Luisa S.B. Pimentel, Zhipeng You, Barbara Morquette, Michaël Nicouleau et al. · 2023 · International Journal of Molecular Sciences
- Human brain organoid: trends, evolution, and remaining challengesMinghui Li, Yuhong Yuan, Zongkun Hou, Shilei Hao, Liang Jin, Bochu Wang · 2023 · Neural Regeneration Research
- Modeling of the brain-lung axis using organoids in traumatic brain injury: an updated reviewJong-Tae Kim, Kang Song, Sung Woo Han, Dong Hyuk Youn, Harry Jung, Keun‐Suh Kim, Hyo‐Jung Lee, Ji Young Hong, Yong-Jun Cho, Sung‐Min Kang et al. · 2024 · Cell & Bioscience
- Proteomics and molecular tools for unveiling missing links in the biochemical understanding of schizophreniaJuliana Minardi Nascimento, Sheila Garcia, Verônica Monteiro Saia-Cereda, Aline Guimarães Santana, Caroline Brandão‐Teles, Giuliana S. Zuccoli, Danielle Gouvêa Junqueira, Guilherme Reis‐de‐Oliveira, Paulo Aparecido Baldasso, Juliana S. Cassoli et al. · 2016 · PROTEOMICS - CLINICAL APPLICATIONS