Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture
Paşca, Anca M, Sloan, Steven A, Clarke, Laura E, Tian, Yuan, Makinson, Christopher D, Huber, Nina, Kim, Chul Hoon, Park, Jin-Young +7 more·2015·Nature Methods
Cited by (1,004)
Items 101–200 of 1,004
- Integrating organoids and organ-on-a-chip devicesYimu Zhao, Shira Landau, Sargol Okhovatian, Chuan Liu, Rick Xing Ze Lu, Benjamin Fook Lun Lai, Qinghua Wu, Jennifer Kieda, Krisco Cheung, Shravanthi Rajasekar et al. · 2024 · Nature Reviews Bioengineering
- Human Models Are Needed for Studying Human Neurodevelopmental DisordersZhao, Xinyu, Bhattacharyya, Anita · 2018 · The American Journal of Human Genetics
- Three Dimensional Human Neuro-Spheroid Model of Alzheimer’s Disease Based on Differentiated Induced Pluripotent Stem CellsLee, Han-Kyu, Velazquez Sanchez, Clara, Chen, Mei, Morin, Peter J., Wells, John M., Hanlon, Eugene B., Xia, Weiming · 2016 · PLOS ONE
- Functionalization of Brain Region-specific Spheroids with Isogenic Microglia-like CellsLiqing Song, Xuegang Yuan, Zachary Jones, Cynthia Vied, Miao Yu, Mark Marzano, Timothy Hua, Qing‐Xiang Amy Sang, Jingjiao Guan, Teng Ma et al. · 2019 · Scientific Reports
- Neuronal defects in a human cellular model of 22q11.2 deletion syndromeKhan, Themasap A., Revah, Omer, Gordon, Aaron, Yoon, Se-Jin, Krawisz, Anna K., Goold, Carleton, Sun, Yishan, Kim, Chul Hoon, Tian, Yuan, Li, Min-Yin et al. · 2020 · Nature Medicine
- Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αvβ5 AxisZhe Zhu, Pinar Mesci, Jean A. Bernatchez, Ryan C. Gimple, Xiuxing Wang, Simon T. Schafer, Hiromi Inoue Wettersten, Sungjun Beck, Alex E. Clark, Qiulian Wu et al. · 2020 · Cell stem cell
- In vitro acute and developmental neurotoxicity screening: an overview of cellular platforms and high-throughput technical possibilitiesBéla Z. Schmidt, Martin Lehmann, Simon Gutbier, Erastus Nembu Nembo, Sabrina Noël, Lena Smirnova, Anna Forsby, Jürgen Hescheler, Hasan X. Avci, Thomas Härtung et al. · 2016 · Archives of Toxicology
- Applications of organoids for cancer biology and precision medicineLo, Yuan-Hung, Karlsson, Kasper, Kuo, Calvin J. · 2020 · Nature Cancer
- A flexible 3-dimensional microelectrode array for in vitro brain models.David A. Soscia, Doris Lam, A. Tooker, Heather A. Enright, M. Triplett, P. Karande, Sandra K. G. Peters, Ana Paula Sales, Elizabeth K. Wheeler, Nicholas O. Fischer · 2020 · Lab on a Chip
- Human brain organoids assemble functionally integrated bilateral optic vesiclesElke Gabriel, Walid Albanna, Giovanni Pasquini, Anand Ramani, Nataša Josipović, Aruljothi Mariappan, Friedrich Schinzel, Celeste M M. Karch, Guobin Bao, Marco Gottardo et al. · 2021 · Cell stem cell
- An atlas of nano-enabled neural interfacesHéctor Acarón Ledesma, Xiaojian Li, João L. Carvalho-de-Souza, Wei Wei, Francisco Bezanilla, Bozhi Tian · 2019 · Nature Nanotechnology
- Potassium channel dysfunction in human neuronal models of Angelman syndromeAlfred Xuyang Sun, Qiang Yuan, Masahiro Fukuda, Weonjin Yu, Hai Yan, Grace Gui Yin Lim, Mui Hoon Nai, Giuseppe Alessandro D’Agostino, Hoang-Dai Tran, Yoko Itahana et al. · 2019 · Science
- A Bio‐Acoustic Levitational (BAL) Assembly Method for Engineering of Multilayered, 3D Brain‐Like Constructs, Using Human Embryonic Stem Cell Derived Neuro‐ProgenitorsCharlène Bouyer, Pu Chen, Sinan Güven, Tuğrul Tolga Demirtaş, Thomas J.F. Nieland, Frederic R. Padilla, Utkan Demirci · 2015 · Advanced Materials
- ELAVL4, splicing, and glutamatergic dysfunction precede neuron loss in MAPT mutation cerebral organoidsBowles, Kathryn R., Silva, M. Catarina, Whitney, Kristen, Bertucci, Taylor, Berlind, Joshua E., Lai, Jesse D., Garza, Jacob C., Boles, Nathan C., Mahali, Sidhartha, Strang, Kevin H. et al. · 2021 · Cell
- Human 3D cellular model of hypoxic brain injury of prematurityPașca, Anca M., Park, Jin-Young, Shin, Hyun-Woo, Qi, Qihao, Revah, Omer, Krasnoff, Rebecca, O’Hara, Ruth, Willsey, A. Jeremy, Palmer, Theo D., Pașca, Sergiu P. · 2019 · Nature Medicine
- Modeling Neurological Diseases With Human Brain OrganoidsHansen Wang · 2018 · Frontiers in Synaptic Neuroscience
- Production of human spinal-cord organoids recapitulating neural-tube morphogenesisJu‐Hyun Lee, Hyogeun Shin, Mohammed R. Shaker, Hyun Jung Kim, Si-Hyung Park, June Hoan Kim, Namwon Lee, MinJin Kang, Subin Cho, Tae Hwan Kwak et al. · 2022 · Nature Biomedical Engineering
- Brain organoids: an ensemble of bioassays to investigate human neurodevelopment and diseaseJaydeep Sidhaye, Juergen A. Knoblich · 2020 · Cell Death and Differentiation
- Viral Strategies for Targeting the Central and Peripheral Nervous SystemsBedbrook, Claire N., Deverman, Benjamin E., Gradinaru, Viviana · 2018 · Annual Review of Neuroscience
- A human forebrain organoid model of fragile X syndrome exhibits altered neurogenesis and highlights new treatment strategiesYunhee Kang, Ying Zhou, Yujing Li, Yanfei Han, Jie Xu, Weibo Niu, Ziyi Li, Shiying Liu, Hao Feng, Wen Huang et al. · 2021 · Nature Neuroscience
- Layered hydrogels accelerate iPSC-derived neuronal maturation and reveal migration defects caused by MeCP2 dysfunctionZhen‐Ning Zhang, Beatriz Freitas, Hao Qian, Jacques Lux, Allan Acab, Cleber A. Trujillo, Roberto H. Herai, Viet Anh Nguyen Huu, Jessica H. Wen, Shivanjali Joshi-Barr et al. · 2016 · Proceedings of the National Academy of Sciences
- SOX Transcription Factors as Important Regulators of Neuronal and Glial Differentiation During Nervous System Development and Adult NeurogenesisMilena J. Stevanović, Danijela Drakulić, Andrijana Lazic, Danijela Stanisavljević Ninković, Marija Schwirtlich, Marija M. Mojsin · 2021 · Frontiers in Molecular Neuroscience
- Transcriptional signatures of schizophrenia in hiPSC-derived NPCs and neurons are concordant with post-mortem adult brainsGabriel E. Hoffman, Brigham J. Hartley, Erin K. Flaherty, Ian Ladran, Peter Gochman, Douglas M. Ruderfer, Eli A. Stahl, Judith L. Rapoport, Pamela B. Sklar, Kristen Brennand · 2017 · Nature Communications
- The Emerging Clinical Neuroscience of Autism Spectrum DisorderRebecca Muhle, Hannah E. Reed, Katharine A. Stratigos, Jeremy M. Veenstra-VanderWeele · 2018 · JAMA Psychiatry
- Orthogonally induced differentiation of stem cells for the programmatic patterning of vascularized organoids and bioprinted tissuesSkylar-Scott, Mark A., Huang, Jeremy Y., Lu, Aric, Ng, Alex H. M., Duenki, Tomoya, Liu, Songlei, Nam, Lucy L., Damaraju, Sarita, Church, George M., Lewis, Jennifer A. · 2022 · Nature Biomedical Engineering
- Scaffolds for 3D in vitro culture of neural lineage cellsAshley R. Murphy, Andrew L. Laslett, Carmel O’Brien, Neil R. Cameron · 2017 · Acta Biomaterialia
- Vascularization of Human Brain OrganoidsTakeshi K. Matsui, Yuichiro Tsuru, Koichi Hasegawa, Ken-ichiro Kuwako · 2021 · Stem Cells
- Expression of the transcription factor PU.1 induces the generation of microglia-like cells in human cortical organoidsBilal Çakır, Yoshiaki Tanaka, Ferdi Rıdvan Kiral, Yangfei Xiang, Onur Dağliyan, Juan Wang, Maria Lee, Allison Marie Greaney, Woo Sub Yang, Catherine duBoulay et al. · 2022 · Nature Communications
- Astrocytes and microglia: Models and toolsKevin A. Guttenplan, Shane Antony Liddelow · 2018 · The Journal of Experimental Medicine
- An integrated transcriptomic cell atlas of human neural organoidsZhisong He, Leander Dony, Jonas Simon Fleck, Artur Szałata, Katelyn X. Li, Irena Slišković, Hsiu‐Chuan Lin, Małgorzata Santel, Alexander Atamian, Giorgia Quadrato et al. · 2024 · Nature
- Kirigami electronics for long-term electrophysiological recording of human neural organoids and assembloidsXiao Yang, Csaba Forró, Thomas L. Li, Yuki Miura, Tomasz J. Zaluska, Ching‐Ting Tsai, Sabina Kanton, James P. McQueen, Xiaoyu Chen, Valentina Mollo et al. · 2024 · Nature Biotechnology
- Making neurons, made easy: The use of Neurogenin-2 in neuronal differentiationAmy E. Hulme, Simon Maksour, Mitchell St Clair‐Glover, Sara Miellet, Mirella Dottori · 2021 · Stem Cell Reports
- Astrocyte Differentiation of Human Pluripotent Stem Cells: New Tools for Neurological Disorder ResearchAbinaya Chandrasekaran, Hasan X. Avci, Marcel Leist, Julianna Kobolák, András Dinnyés · 2016 · Frontiers in Cellular Neuroscience
- Recapitulating cortical development with organoid culture in vitro and modeling abnormal spindle-like (ASPM related primary) microcephaly diseaseRui Li, Le Sun, Ai Fang, Peng Li, Qian Wu, Xiaoqun Wang · 2017 · Protein & Cell
- Nondestructive nanostraw intracellular sampling for longitudinal cell monitoringYuhong Cao, Martin Hjort, Haodong Chen, Fikri Birey, Sergio Leal‐Ortiz, Crystal M. Han, Juan Gabriel Santiago, Sergiu P. Pașca, Joseph C. Wu, Nicholas A. Melosh · 2017 · Proceedings of the National Academy of Sciences
- Schizophrenia is defined by cell-specific neuropathology and multiple neurodevelopmental mechanisms in patient-derived cerebral organoidsNotaras, Michael, Lodhi, Aiman, Dündar, Friederike, Collier, Paul, Sayles, Nicole M., Tilgner, Hagen, Greening, David, Colak, Dilek · 2022 · Molecular Psychiatry
- An in Vivo miRNA Delivery System for Restoring Infarcted MyocardiumHuaxiao Yang, Xulei Qin, Huiyuan Wang, Xin Zhao, Yonggang Liu, Hung-Ta Wo, Chun Liu, Masataka Nishiga, Haodong Chen, Jing Ge et al. · 2019 · ACS Nano
- Rotenone exerts developmental neurotoxicity in a human brain spheroid modelDavid Pamies, Katharina Block, Pierre Lau, Laura Gribaldo, Carlos A. Pardo, Paula Barreras, Lena Smirnova, Daphne Wiersma, Liang Zhao, Georgina Harris et al. · 2018 · Toxicology and Applied Pharmacology
- Organ-On-A-Chip in vitro Models of the Brain and the Blood-Brain Barrier and Their Value to Study the Microbiota-Gut-Brain Axis in NeurodegenerationIlaria Raimondi, Luca Izzo, Marta Tunesi, Manola Comar, Diego Albani, Carmen Giordano · 2020 · Frontiers in Bioengineering and Biotechnology
- Modelling human brain development and disease with organoidsMarcella Birtele, Madeline A. Lancaster, Giorgia Quadrato · 2024 · Nature Reviews Molecular Cell Biology
- Human iPSC‐derived microglia: A growing toolset to study the brain's innate immune cellsHasselmann, Jonathan, Blurton‐Jones, Mathew · 2020 · Glia
- Stem cell models of Alzheimer’s disease: progress and challengesArber, Charles, Lovejoy, Christopher, Wray, Selina · 2017 · Alzheimer's Research & Therapy
- Spatially controlled construction of assembloids using bioprintingJulien George Roth, Lucia Giulia Brunel, Michelle S. Huang, Yueming Liu, Betty Cai, Sauradeep Sinha, Fan Yang, Sergiu P. Pașca, Sungchul Shin, Sarah C. Heilshorn · 2023 · Nature Communications
- Complex Tissue and Disease Modeling using hiPSCsPassier, Robert, Orlova, Valeria, Mummery, Christine · 2016 · Cell Stem Cell
- Stem Cells, Genome Editing, and the Path to Translational MedicineFrank Soldner, Rudolf Jaenisch · 2018 · Cell
- Vascularized microfluidic organ-chips for drug screening, disease models and tissue engineeringOsaki, Tatsuya, Sivathanu, Vivek, Kamm, Roger D · 2018 · Current Opinion in Biotechnology
- Fluorescent nanodiamond tracking reveals intraneuronal transport abnormalities induced by brain-disease-related genetic risk factorsSimon Haziza, Nitin Mohan, Yann Loe-Mie, Aude-Marie Lepagnol-Bestel, Sophie Massou, Marie‐Pierre Adam, Loc Le Xuan, Julia Viard, Christine Plançon, Rachel Daudin et al. · 2016 · Nature Nanotechnology
- Drug screening for human genetic diseases using iPSC modelsMatthew S. Elitt, Lilianne Barbar, Paul J. Tesar · 2018 · Human Molecular Genetics
- Applications of Human Brain Organoids to Clinical ProblemsHan-Chiao Isaac Chen, Hongjun Song, Guo‐li Ming · 2018 · Developmental Dynamics
- In situ generation of human brain organoids on a micropillar arrayYujuan Zhu, Li Wang, Hao Yu, Fangchao Yin, Yaqing Wang, Haitao Liu, Lei Jiang, Jianhua Qin · 2017 · Lab on a Chip
- Cortical organoids model early brain development disrupted by 16p11.2 copy number variants in autismJorge Urresti, Pan Zhang, Patricia Morán Losada, Nam‐Kyung Yu, Priscilla Davidson Negraes, Cleber A. Trujillo, Danny Antaki, Megha Amar, Kevin K. Chau, Akula Bala Pramod et al. · 2021 · Molecular Psychiatry
- 3D bioprinting of human neural tissues with functional connectivityYuanwei Yan, Xueyan Li, Yu Gao, Sakthikumar Mathivanan, Linghai Kong, Yunlong Tao, Yi Wei Dong, Xiang Li, Anita Bhattacharyya, Xinyu Zhao et al. · 2024 · Cell stem cell
- Human assembloid model of the ascending neural sensory pathwayJi‐il Kim, Kent Imaizumi, Ovidiu F. Jurjuţ, Kevin W. Kelley, Dong Wang, Mayuri Vijay Thete, Zuzana Hudáčová, Neal D. Amin, Rebecca J. Levy, Grégory Scherrer et al. · 2025 · Nature
- Brain Organoids and the Study of NeurodevelopmentCleber A. Trujillo, Alysson Renato Muotri · 2018 · Trends in Molecular Medicine
- Structural and functional integration of human forebrain organoids with the injured adult rat visual systemDennis Jgamadze, James T. Lim, Zhijian Zhang, Paul M. Harary, James Germi, Kobina G. Mensah-Brown, Christopher D. Adam, Ehsan Mirzakhalili, Shikha Singh, Jiahe Ben Gu et al. · 2023 · Cell stem cell
- Pluripotent Stem Cell-Derived Cerebral Organoids Reveal Human Oligodendrogenesis with Dorsal and Ventral OriginsHyosung Kim, Ranjie Xu, Ragunathan Padmashri, Anna Dunaevsky, Ying Liu, Cheryl F. Dreyfus, Peng Jiang · 2019 · Stem Cell Reports
- Pluripotent stem cells in neuropsychiatric disordersM A Soliman, Farid Aboharb, Nadja Zeltner, Lorenz Studer · 2017 · Molecular Psychiatry
- Microglia Increase Inflammatory Responses in iPSC-Derived Human BrainSpheresCelina Monteiro Abreu, Lúcio Gama, Susanne Krasemann, Megan Chesnut, Shelly Odwin-DaCosta, Helena T. Högberg, Thomas Härtung, David Pamies · 2018 · Frontiers in Microbiology
- Neural Substrate Expansion for the Restoration of Brain FunctionHan-Chiao Isaac Chen, Dennis Jgamadze, Mijail Demian Serruya, D. Kacy Cullen, John A. Wolf, Douglas H. Smith · 2016 · Frontiers in Systems Neuroscience
- Neuronal migration in the CNS during development and disease: insights from in vivo and in vitro modelsIsabel Y. Buchsbaum, Silvia Cappello · 2019 · Development
- Engineering induction of singular neural rosette emergence within hPSC-derived tissuesGavin T. Knight, Brady F. Lundin, Nisha R. Iyer, Lydia Ashton, William A. Sethares, Rebecca M. Willett, Randolph Scott Ashton · 2018 · eLife
- Modeling Alzheimer's disease with human induced pluripotent stem (iPS) cellsAlison E. Mungenast, Sandra Siegert, Li‐Huei Tsai · 2015 · Molecular and Cellular Neuroscience
- Anisotropically organized three-dimensional culture platform for reconstruction of a hippocampal neural networkKim Ys, Sun-Kyoung Im, Soo‐Jin Oh, Sohyeon Jeong, Eui-Sung Yoon, Changjoon Justin Lee, Nakwon Choi, Eun‐Mi Hur · 2017 · Nature Communications
- Convergence of microengineering and cellular self-organization towards functional tissue manufacturingJérémie Laurent, Guillaume Blin, François Chatelain, Valérie Vanneaux, Alexandra Fuchs, Jérôme Larghero, Manuel Théry · 2017 · Nature Biomedical Engineering
- Three-dimensional modeling of human neurodegeneration: brain organoids coming of ageKarl Grenier, Jennifer Kao, Phedias Diamandis · 2019 · Molecular Psychiatry
- Antisense oligonucleotide therapeutic approach for Timothy syndromeXiaoyu Chen, Fikri Birey, Min-Yin Li, Omer Revah, Rebecca J. Levy, Mayuri Vijay Thete, Noah Reis, Konstantin Kaganovsky, Massimo M. Onesto, Noriaki Sakai et al. · 2024 · Nature
- The Gut-Brain Axis in Inflammatory Bowel Disease—Current and Future PerspectivesGünther, Claudia, Rothhammer, Veit, Karow, Marisa, Neurath, Markus, Winner, Beate · 2021 · International Journal of Molecular Sciences
- Comparison of 2D and 3D neural induction methods for the generation of neural progenitor cells from human induced pluripotent stem cellsAbinaya Chandrasekaran, Hasan X. Avci, Anna Ochałek, Lone Rösingh, Kinga Molnár, Lajos László, Tamás Bellák, Annamária Téglási, Krisztina Pesti, Alyssa Mike et al. · 2017 · Stem Cell Research
- Old but Gold: Tracking the New Guise of Histone Deacetylase 6 (HDAC6) Enzyme as a Biomarker and Therapeutic Target in Rare DiseasesMargherita Brindisi, Akella Prasanth Saraswati, Simone Brogi, Sandra Gemma, Stefania Butini, Giuseppe Campiani · 2019 · Journal of Medicinal Chemistry
- Transplantation of Human Brain Organoids: Revisiting the Science and Ethics of Brain ChimerasH. Isaac Chen, John A. Wolf, Rachel Blue, Mingyan Maggie Song, Jonathan D. Moreno, Guo‐li Ming, Hongjun Song · 2019 · Cell stem cell
- Microglia-like Cells Promote Neuronal Functions in Cerebral OrganoidsIlkka Fagerlund, Antonios Dougalis, Anastasia Shakirzyanova, Mireia Gómez‐Budia, Anssi Pelkonen, Henna Konttinen, Sohvi Ohtonen, Mohammad Feroze Fazaludeen, Marja Koskuvi, Johanna Kuusisto et al. · 2021 · Cells
- Advancing models of neural development with biomaterialsJulien George Roth, Michelle S. Huang, Thomas L. Li, Vivian Rachel Feig, Yuanwen Jiang, Bianxiao Cui, Henry T. Greely, Zhenan Bao, Sergiu P. Pașca, Sarah C. Heilshorn · 2021 · Nature reviews. Neuroscience
- Open Chromatin Profiling in hiPSC-Derived Neurons Prioritizes Functional Noncoding Psychiatric Risk Variants and Highlights Neurodevelopmental LociMarc P. Forrest, Hanwen Zhang, Winton Moy, Heather McGowan, Catherine Leites, Leonardo E. Dionisio, Zihui Xu, Jianxin Shi, Alan R. Sanders, William James Greenleaf et al. · 2017 · Cell stem cell
- Studying Human Neurological Disorders Using Induced Pluripotent Stem Cells: From 2D Monolayer to 3D Organoid and Blood Brain Barrier ModelsSarah Logan, Thiago Arzua, Scott Glen Canfield, Emily R. Seminary, Samantha L. Sison, Allison D. Ebert, Xiaowen Bai · 2019 · Comprehensive physiology
- Resolving organoid brain region identities by mapping single-cell genomic data to reference atlasesFleck, Jonas Simon, Sanchís-Calleja, Fátima, He, Zhisong, Santel, Malgorzata, Boyle, Michael James, Camp, J. Gray, Treutlein, Barbara · 2021 · Cell Stem Cell
- MicroRNA-9 Couples Brain Neurogenesis and AngiogenesisRomain Madelaine, Steven A. Sloan, Nina Huber, James H. Notwell, Louis C. Leung, Gemini M. Skariah, Caroline Halluin, Sergiu P. Pașca, Gill Bejerano, Mark A. Krasnow et al. · 2017 · Cell Reports
- Functional characterization of human pluripotent stem cell-derived cortical networks differentiated on laminin-521 substrate: comparison to rat cortical culturesTanja Hyvärinen, Anu Hyysalo, Fikret Emre Kapucu, Laura Aarnos, Andrey Vinogradov, Stephen J. Eglen, Laura Ylä‐Outinen, Susanna Narkilahti · 2019 · Scientific Reports
- Developmental GABA polarity switch and neuronal plasticity in Bioengineered Neuronal OrganoidsMaria-Patapia Zafeiriou, Guobin Bao, James E. Hudson, Rashi Halder, Alica Blenkle, Marie-Kristin Schreiber, André Fischer, Detlev Schild, Wolfram‐Hubertus Zimmermann · 2020 · Nature Communications
- Brain Organoids: Human Neurodevelopment in a DishSilvia K. Benito-Kwiecinski, Madeline A. Lancaster · 2019 · Cold Spring Harbor Perspectives in Biology
- Advances in Zika Virus Research: Stem Cell Models, Challenges, and OpportunitiesGuo‐li Ming, Hengli Tang, Hongjun Song · 2016 · Cell stem cell
- Human Huntington's disease iPSC-derived cortical neurons display altered transcriptomics, morphology, and maturationMehta, Shagun R., Tom, Colton M., Wang, Yizhou, Bresee, Catherine, Rushton, David, Mathkar, Pranav P., Tang, Jie, Mattis, Virginia B. · 2018 · Cell Reports
- Generation of homogeneous midbrain organoids with in vivo-like cellular composition facilitates neurotoxin-based Parkinson's disease modelingTae Hwan Kwak, Ji Hyun Kang, Sai Hali, Jonghun Kim, Kee-Pyo Kim, Chanhyeok Park, Ju‐Hyun Lee, Ha Kyun Ryu, Ji Eun Na, Junghyun Jo et al. · 2020 · Stem Cells
- Electrophysiological Analysis of Brain Organoids: Current Approaches and AdvancementsAustin P. Passaro, Steven L. Stice · 2021 · Frontiers in Neuroscience
- Human Organoids for Predictive Toxicology Research and Drug DevelopmentMatsui, Toshikatsu, Shinozawa, Tadahiro · 2021 · Frontiers in Genetics
- Revisiting adult neurogenesis and the role of erythropoietin for neuronal and oligodendroglial differentiation in the hippocampusImam A. Hassouna, C Ott, Liane Wüstefeld, Nils Offen, Richard A. Neher, Mišo Mitkovski, Daniela Winkler, Swetlana Sperling, Lennart Fries, Sandra Goebbels et al. · 2016 · Molecular Psychiatry
- Probing human brain evolution and development in organoidsStefano L. Giandomenico, Madeline A. Lancaster · 2017 · Current Opinion in Cell Biology
- Composite Hydrogels in Three-Dimensional in vitro ModelsZhitong Zhao, Catarina Vizetto‐Duarte, Zi Kuang Moay, Magdiel Inggrid Setyawati, Moumita Rakshit, Mustafa Hussain Kathawala, Kee Woei Ng · 2020 · Frontiers in Bioengineering and Biotechnology
- Assessing similarity to primary tissue and cortical layer identity in induced pluripotent stem cell-derived cortical neurons through single-cell transcriptomicsAdam E. Handel, Satyan Chintawar, Tatjana Lalic, Emma S. Whiteley, Jane Vowles, Alice Giustacchini, Karène Argoud, Paul Sopp, Mahito Nakanishi, Rory J. Bowden et al. · 2016 · Human Molecular Genetics
- Cerebral organoids derived from Sandhoff disease-induced pluripotent stem cells exhibit impaired neurodifferentiationMaría L. Allende, Emily K. Cook, Bridget C. Larman, Adrienne Nugent, Jacqueline M. Brady, Diane Golebiowski, Miguel Sena‐Esteves, Cynthia J. Tifft, Richard L. Proia · 2018 · Journal of Lipid Research
- 3D Brain Organoids: Studying Brain Development and Disease Outside the EmbryoSilvia Velasco, Bruna da Silveira Paulsen, Paola Arlotta · 2020 · Annual Review of Neuroscience
- Engineering Hydrogels for the Development of Three-Dimensional In Vitro ModelsSomnath Maji, Hyungseok Lee · 2022 · International Journal of Molecular Sciences
- Assembloid models of cell-cell interaction to study tissue and disease biologyOnesto, Massimo M., Kim, Ji-il, Pasca, Sergiu P. · 2024 · Cell Stem Cell
- Human fetal brain self-organizes into long-term expanding organoidsDelilah F. G. Hendriks, Anna Pagliaro, Francesco Andreatta, Ziliang Ma, Joey van Giessen, Simone Massalini, Carmen López‐Iglesias, Gijs J. F. van Son, Jeff DeMartino, Mirjam J. A. Damen et al. · 2024 · Cell
- Advances in microfluidic in vitro systems for neurological disease modelingPaul M. Holloway, Sandrine Willaime‐Morawek, Richard C. M. Siow, Melissa Barber, Róisı́n M. Owens, Anup Dutt Sharma, Wendy C. Rowan, Eric James Hill, Michele Zagnoni · 2021 · Journal of Neuroscience Research
- Three‐Dimensional Models of the Human Brain Development and DiseasesMehdi Jorfi, Carla D’Avanzo, Doo Yeon Kim, Daniel Irimia · 2017 · Advanced Healthcare Materials
- Upgrading the Physiological Relevance of Human Brain OrganoidsAshley Del Dosso, Jean‐Paul Urenda, Tuan N. Nguyen, Giorgia Quadrato · 2020 · Neuron
- Human iPSC-Derived Neural Models for Studying Alzheimer’s Disease: from Neural Stem Cells to Cerebral OrganoidsMartin Barák, Veronika Fedorová, Veronika Pospíšilová, Jan Raška, Simona Vochyánová, Jiří Sedmík, Hana Hříbková, Hana Klímová, Tereza Váňová, Dáša Bohačiaková · 2022 · Stem Cell Reviews and Reports
- Crosstalk between small-cell lung cancer cells and astrocytes mimics brain development to promote brain metastasisFangfei Qu, Siqi C. Brough, Wojciech Michno, Chioma J. Madubata, Griffin G. Hartmann, Alyssa Puno, Alexandros P. Drainas, Debadrita Bhattacharya, Erwin Tomasich, Myung Chang Lee et al. · 2023 · Nature Cell Biology
- Tissue morphology influences the temporal program of human brain organoid developmentIlaria Chiaradia, Iván Imaz-Rosshandler, Benedikt S. Nilges, Jérôme Boulanger, Laura Pellegrini, Richa Das, Nachiket Dilip Kashikar, Madeline A. Lancaster · 2023 · Cell stem cell
- Systematic Three-Dimensional Coculture Rapidly Recapitulates Interactions between Human Neurons and AstrocytesRobert Krencik, Kyounghee Seo, Jessy V. van Asperen, Nupur Basu, Caroline Cvetkovic, Saba Barlas, Robert Yuzen Chen, Connor Ludwig, Chao Wang, Michael Emmerson Ward et al. · 2017 · Stem Cell Reports