Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture

Paşca, Anca M, Sloan, Steven A, Clarke, Laura E, Tian, Yuan, Makinson, Christopher D, Huber, Nina, Kim, Chul Hoon, Park, Jin-Young +7 more·2015·Nature Methods

DOI 10.1038/nmeth.3415

Cited by (1,004)

Items 301–400 of 1,004

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Csaba Forró, Davide Caron, Gian Nicola Angotzi, Vincenzo Gallo, Luca Berdondini, Francesca Santoro, Gemma Palazzolo, Gabriella Panuccio · 2021 · Micromachines
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