The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
irCLIP platform for efficient characterization of protein–RNA interactions
Open accessAbstract
The complexity of transcriptome-wide protein–RNA interaction networks is incompletely understood. While emerging studies are greatly expanding the known universe of RNA-binding proteins, methods for the discovery and characterization of protein–RNA interactions remain resource intensive and technically challenging. Here we introduce a UV-C crosslinking and immunoprecipitation platform, irCLIP, which provides an ultraefficient, fast, and nonisotopic method for the detection of protein–RNA interactions using far less material than standard protocols.
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Insights into RNA Biology from an Atlas of Mammalian mRNA-Binding Proteins
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HITS-CLIP yields genome-wide insights into brain alternative RNA processing
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iCLIP reveals the function of hnRNP particles in splicing at individual nucleotide resolution
König, J., Zarnack, K., Rot, G., Curk, T., Kayikci, M., Zupan, B., Turner, D. J., Luscombe, N. M., & Ule, J. (2010) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1838 · Cited by 1,126
Transcriptome-wide Analysis of Regulatory Interactions of the RNA-Binding Protein HuR
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Pereira, B., Billaud, M., & Almeida, R. (2017) · Trends in Cancer · doi:10.1016/j.trecan.2017.05.003 · Cited by 773
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RNA–protein interaction detection in living cells
Ramanathan, M., Majzoub, K., Rao, D. S., Neela, P. H., Zarnegar, B. J., Mondal, S., Roth, J. G., Gai, H., Kovalski, J. R., Siprashvili, Z., et al. (2018) · Nature Methods · doi:10.1038/nmeth.4601 · Cited by 308
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He, C., Bozler, J., Janssen, K. A., Wilusz, J. E., Garcia, B. A., Schorn, A. J., & Bonasio, R. (2021) · Nature Structural & Molecular Biology · doi:10.1038/s41594-020-00526-w · Cited by 83
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Scalable and deep profiling of mRNA targets for individual microRNAs with chimeric eCLIP
Manakov, S. A., Shishkin, A. A., Yee, B. A., Shen, K. A., Cox, D. C., Park, S. S., Foster, H. M., Chapman, K. B., Yeo, G. W., & Van Nostrand, E. L. (2022) · doi:10.1101/2022.02.13.480296 · Cited by 43
Bjerke, G. A., & Yi, R. (2020) · RNA · doi:10.1261/rna.073635.119 · Cited by 22
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Metadata
- Authors
- Zarnegar, B. J., Flynn, R. A., Shen, Y., Do, B. T., Chang, H. Y., & Khavari, P. A.
- Venue
- Nature Methods
- Published
- 2016-04-25
- Volume
- 13
- Issue
- 6
- Pages
- 489-492
- ISSN
- 1548-7091 (ISSN-L)
- 1548-7105
- OpenAlex
- W2342788749
- Cited by
- 262
- References
- 8
- FWCI
- 13.54
- Type
- journal article
- Language
- en
- Open access
- green
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