CIRCLE-Seq: A highly sensitive in vitro screen for genome-wide CRISPR-cas9 nuclease off-targets

Tsai, Shengdar Q, Nguyen, Nhu T, Malagon-Lopez, Jose, Topkar, Ved V, Aryee, Martin J, Joung, J Keith·2017·Nature Methods

Cited by (816)

Items 401–500 of 816

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  10. Haplotyping by CRISPR-mediated DNA circularization (CRISPR-hapC) broadens allele-specific gene editing
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  17. Genotyping-by-Sequencing in Vigna unguiculata Landraces and Its Utility for Assessing Taxonomic Relationships
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  22. Preventing secondary primary malignancies (SPMs) in CAR-T cell therapy through site-specific transgene integration into genomic safe harbors (GSHs)
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  35. Gene editing as a promising approach for respiratory diseases
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  36. Unexpectedly High Levels of Inverted Re-Insertions Using Paired sgRNAs for Genomic Deletions
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  40. AI-driven advances in plant biotechnology: sharpening the edge of plant tissue culture and genome editing
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  43. OliTag-seq enhances in cellulo detection of CRISPR-Cas9 off-targets
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  45. Recent developments with advancing gene therapy to treat chronic infection with hepatitis B virus
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  46. Element coding based accurate evaluation of CRISPR/Cas9 initial cleavage
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  47. Full-Length Dystrophin Restoration via Targeted Exon Addition in DMD-Patient Specific iPSCs and Cardiomyocytes
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  49. Comprehensive Analysis of CRISPR/Cas9-Mediated Mutagenesis in Arabidopsis thaliana by Genome-Wide Sequencing
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  50. Evaluation of the CRISPR/Cas9 Genetic Constructs in Efficient Disruption of Porcine Genes for Xenotransplantation Purposes Along with an Assessment of the Off-Target Mutation Formation
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  51. Critical cancer vulnerabilities identified by unbiased CRISPR/Cas9 screens inform on efficient cancer Immunotherapy
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  58. Topology‐Engineered Guide RNAs for Programmable Control of CRISPR/Cas Activity
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