CIRCLE-Seq: A highly sensitive in vitro screen for genome-wide CRISPR-cas9 nuclease off-targets

Tsai, Shengdar Q, Nguyen, Nhu T, Malagon-Lopez, Jose, Topkar, Ved V, Aryee, Martin J, Joung, J Keith·2017·Nature Methods

Cited by (816)

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  2. An atypical CRISPR-Cas locus in Symbiobacterium thermophilum flanked by a transposase, a reverse transcriptase, the endonuclease MutS2 and a putative Cas9-like protein
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  9. Detection and Quantification of Genome Editing Events in Preclinical and Clinical Studies
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  13. DeepEmbCas9: Cas9 coevolution and sgRNA structural information for CRISPR-Cas9 cleavage activity prediction
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  14. A mechanistic free-energy model explains and predicts sequence- and context-dependent CRISPR–Cas9 activity
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  15. High-throughput in vitro specificity profiling of natural and high-fidelity CRISPR-Cas9 variants
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  16. Genomeditierung in der Zell- und Gentherapie
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  19. Rapid Proteomic Screen of CRISPR Experiment Outcome by Data Independent Acquisition Mass Spectrometry: A Case Study for HMGN1
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  34. Diminished adherence of Biomphalaria glabrata embryonic cell line to sporocysts of Schistosoma mansoni following programmed knockout of the allograft inflammatory factor
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  35. Diminished Adherence of Biomphalaria Glabrata Embryonic Cell Line to Sporocysts of Schistosoma Mansoni Following Programmed Knockout of the Allograft Inflammatory Factor
    Fernanda Sales Coelho, Rutchanee Rodpai, André Miller, Shannon E. Karinshak, Victoria H. Mann, Omar dos Santos Carvalho, Roberta Lima Cladeira, Marina de Moraes Mourão, Paul J. Brindley, Wannaporn Ittiprasert · 2020 · Research Square
  36. Faculty Opinions recommendation of In vivo CRISPR editing with no detectable genome-wide off-target mutations.
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