CRISPR-STOP: gene silencing through base-editing-induced nonsense mutations

Kuscu, Cem, Parlak, Mahmut, Tufan, Turan, Yang, Jiekun, Szlachta, Karol, Wei, Xiaolong, Mammadov, Rashad, Adli, Mazhar·2017·Nature Methods
DOI 10.1038/nmeth.4327

Cited by (335)

Items 301–335 of 335

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  3. Generating a New sgRNA Vector, pGL3-U6-sgRNA-PGK-mRFP-T2A-PuroR, to Improve Base Editing
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  4. CRISPR-cas technology and use in antiviral development
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  5. CRISPR-Cas Genome Editing: Another Revolution in Molecular Biology
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  6. CRISPR-based Technologies for Genome Engineering: Properties, Current Improvements and Applications in Medicine
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  7. Genetic Manipulation of the Embryonic Chicken Inner Ear
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  8. Sequence Diversification Screens with CRISPR‐Cas9‐Guided Base Editors
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  9. Cryptography in the DNA of living cells enabled by multi-site base editing
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  10. Cas Variants Increased the Dimension of the CRISPR Tool Kit
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  11. Genome editing: from tools to biological insights
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  12. Gene editing and central nervous system regeneration
    Sara Monteiro Lopes, Luís Pereira de Almeida · 2020 · Elsevier eBooks
  13. CRISPR/Cas9 Technology: Making Possibilities against Breast Cancer
    V. Sanjuvikasini, S. Shruthi, M. Vijay Pradhap Singh · 2020 · International Journal of Pharmaceutical Sciences Review and Research
  14. DNA Base Editing Strategies for Genome Editing
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  15. Faculty Opinions recommendation of The CRISPR tool kit for genome editing and beyond.
    Søren Warming · 2018 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  16. Designing Guide-RNA for Generating Premature Stop Codons for Gene Knockout Using CRISPR-BETS
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  17. CRISPR-based precision breeding of fruits, vegetables, and ornamental plants
    Mohamed A. M. Atia, Arwa Salah, Aisha Elsawah, Ahmed Karam, Taghreed Khaled Abdelmoneim · 2024 · Elsevier eBooks
  18. Precise and adaptable knock-out generation in wheat thanks to a multi-stop cassette
    Maxime Kadner, Stéphane BENEDIT, Wyatt Paul, Jean-Philippe Pichon, Caroline Tassy, P. Barret · 2024 · Research Square
  19. Multifaceted roles of CRISPR technology in blood cancer research
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  20. Minimal activation of the p53 DNA damage response by a modular cytosine base editor enables effective multiplexed gene knockout in induced pluripotent stem cells
    Robert A. Blassberg, Olga Mielczarek, Jesse Stombaugh, Hanneke Okkenhaug, Alice A. Torres, Paul Russell, John J. Lambourne, Immacolata Porreca · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  21. Establishment and rescue of fibroblast cell lines carrying a nonsense mutation of RB1 by CRISPR-based base editing
    Youngri Jung, Eunhee Seo, Soyeon Yang, Sangsu Bae, Jeong Hun Kim, Hyeon‐Ki Jang, Dong‐Gyu Jo · 2025 · Scientific Reports
  22. Analysis of Cytosine Base Editors in Bovine Zygotes: Efficiency and Editing Window Characterization Through Targeting the MYO7A Gene
    Junghyun Ryu, Rebecca Tippner-Hedges, Martha Neuringer, Jon D. Hennebold · 2025 · Current Issues in Molecular Biology
  23. High-throughput editing boosts the construction of next-generation microbial cell factories
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  24. Dissecting multi-gene virulence phenotypes with base editing requires consideration of target-independent mutagenesis
    Joshua P. M. Newson, Sandra Gawlitt, Sneha Sundar, Roland R. Regoes, Chase L. Beisel, Wolf‐Dietrich Hardt · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  25. Engineering Prime Editing System for Concurrent Gene Knockout and Point Mutation Induction (KAPSi) in Rice
    Liu Xiaoshuang, Chong MA, Wang Dongmei, Youshen XU, Ruiying Qin, Li Juan, Xu Rongfang, Wei Pengcheng · 2026 · Rice Science
  26. The functional landscape of STK35 residues at single-amino-acid resolution in the DNA damage response and genotoxic drug vulnerability
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  27. Cytosine base editing workflow for quality-controlled multiplex-knockout hiPSC lines
    Vanessa Kirschner, Julia Herzberg, Christin Richter, Sayari Bhunia, Rebecca Kistler, Roger Ottenheijm, Timon Seeger, Marc Freichel, Alex Cornean · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  28. Incorporating AI-optimized zinc finger proteins enhances the efficiencies and targeting ranges of miniature base editors
    Qianyue Huang, Dian Yang, Xi-Bin Zhou, Geng Li, Weikuan Liu, Xiaoqi Fan, Fa-Jie Yuan, Xing Chang · 2026 · Nature Communications
  29. CRISPR-Cas9 gene editing approaches in colorectal cancer: Current progress and future prospects
    Mohadeseh Hassannia, Parisa Amirifar · 2026 · Cancer Treatment and Research Communications
  30. Interplay Between Base Editing and DNA repair: From Molecular Mechanisms to Clinical Translation
    Rui Tao, Min Li, Tongyun Luo, Shaohua Yao · 2026 · Biotechnology Advances
  31. A multiplex genome editing pipeline for rapid combinatorial trait engineering
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  32. Genetically engineered hypoimmunogenic iPSCs: Strategies and considerations for clinical applications
    Jason K.M. Choi, Akitsu Hotta · 2026 · Regenerative Therapy
  33. Base editing-mediated induction of stop codons in HPV18 E6/E7 for cervical cancer therapy
    Yue Kang, Yifan Wu, Bingting Bao, Xueqian Wang, Zhiqiang Yu, Chen Cao, Zhi Wang, 王兆杰, Gang Chen, Ding Ma et al. · 2026 · Molecular Therapy
  34. A base-editing and auxotrophic selection platform for linking epigenetic regulators to silent biosynthetic gene clusters in Aspergillus nidulans
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  35. From base transitions to expanded editing tools: development and applications of plant base editors
    Ning Sui, Jiekun Zhang, Wenyue Xu, 庞美新, Ruixiang Zhang, Nan Chai, Jun Wen, Taoli Liu, Zhiye Zheng, Jingyang Huang et al. · 2026 · Biotechnology Advances