Scenic: single-cell regulatory network inference and clustering.
Aibar, Sara, González-Blas, Carmen Bravo, Moerman, Thomas, Huynh-Thu, Vân Anh, Imrichova, Hana, Hulselmans, Gert, Rambow, Florian, Marine, Jean-Christophe +6 more·2017·Nature Methods
Cited by (1,038)
Items 501–600 of 1,038
- Single-cell transcriptomics identifies gene expression networks driving differentiation and tumorigenesis in the human fallopian tubeHuy Q. Dinh, Xianzhi Lin, Forough Abbasi, Robbin A. Nameki, Marcela Haro, Claire E. Olingy, Heidi S. Y. Chang, Lourdes Hernández, Simon A. Gayther, Kelly Nicole Wright et al. · 2021 · Cell Reports
- Single-nucleus transcriptome analysis of human brain immune response in patients with severe COVID-19John F. Fullard, Hao-Chih Lee, Georgios Voloudakis, Shengbao Suo, Behnam Javidfar, Zhiping Shao, Cyril Jayakumar Peter, Wen Zhang, Shan Jiang, André Corvelo et al. · 2021 · Genome Medicine
- Single cell RNA-seq reveals the CCL5/SDC1 receptor-ligand interaction between T cells and tumor cells in pancreatic cancerKai Chen, Yazhou Wang, Yuting Hou, Qi Wang, Di Long, Xinxin Liu, Xiaodong Tian, Yinmo Yang · 2022 · Cancer Letters
- Polygenic regression uncovers trait-relevant cellular contexts through pathway activation transformation of single-cell RNA sequencing dataYunlong Ma, Chunyu Deng, Yijun Zhou, Yaru Zhang, Fei Qiu, Dingping Jiang, Gongwei Zheng, Jingjing Li, Jianwei Shuai, Yan Zhang et al. · 2023 · Cell Genomics
- Systematic identification of cell-fate regulatory programs using a single-cell atlas of mouse developmentLijiang Fei, Haide Chen, Lifeng Ma, E Weigao, Renying Wang, Xing Fang, Ziming Zhou, Huiyu Sun, Jingjing Wang, Mengmeng Jiang et al. · 2022 · Nature Genetics
- Single-cell dissection of the obesity-exercise axis in adipose-muscle tissues implies a critical role for mesenchymal stem cellsJiekun Yang, Maria T. Vamvini, Pasquale Nigro, Li‐Lun Ho, Kyriaki Galani, Marcus Alvarez, Yosuke Tanigawa, Ashley Renfro, Nicholas P. Carbone, Markku Laakso et al. · 2022 · Cell Metabolism
- Individual cell types in C. elegans age differently and activate distinct cell-protective responsesAntoine E. Roux, Han Yuan, Katie Podshivalova, David G. Hendrickson, Rex A. Kerr, Cynthia J. Kenyon, David R. Kelley · 2023 · Cell Reports
- SERGIO: A Single-Cell Expression Simulator Guided by Gene Regulatory NetworksPayam Dibaeinia, Saurabh Sinha · 2020 · Cell Systems
- Innovative breakthroughs facilitated by single-cell multi-omics: manipulating natural killer cell functionality correlates with a novel subcategory of melanoma cellsZhijie Zhao, Yantao Ding, Lisa Jia Tran, Gang Chai, Lin Li · 2023 · Frontiers in Immunology
- SCENIC+: single-cell multiomic inference of enhancers and gene regulatory networksGonzález-Blas, Carmen Bravo, De Winter, Seppe, Hulselmans, Gert, Hecker, Nikolai, Matetovici, Irina, Christiaens, Valerie, Poovathingal, Suresh, Wouters, Jasper, Aibar, Sara, Aerts, Stein · 2022
- Cell Lineage-Based Stratification for GlioblastomaZilai Wang, Daochun Sun, Yu-Jung Chen, Xuanhua Xie, Yufeng Shi, Viviane S. Tabar, Cameron Walter Brennan, Tejus Bale, Chenura D. Jayewickreme, Dan R. Laks et al. · 2020 · Cancer Cell
- Imputing single-cell RNA-seq data by combining graph convolution and autoencoder neural networksJiahua Rao, Xiang Zhou, Yutong Lu, Huiying Zhao, Yuedong Yang · 2021 · iScience
- Single-cell analysis of psoriasis resolution demonstrates an inflammatory fibroblast state targeted by IL-23 blockadeLuc Francis, Daniel McCluskey, Clarisse Gânier, Treasa Jiang, Xinyi Du-Harpur, Jeyrroy Gabriel, Pawan Dhami, Yogesh Kamra, Sudha Visvanathan, Jonathan N. Barker et al. · 2024 · Nature Communications
- Reticular Fibroblasts Expressing the Transcription Factor WT1 Define a Stromal Niche that Maintains and Replenishes Splenic Red Pulp MacrophagesAlicia Bellomo, Isabelle Mondor, Lionel Spinelli, Marine Lagueyrie, Benjamin J. Stewart, Nicolas Brouilly, Bernard MALISSEN, Menna Ruth Clatworthy, Marc Bajénoff · 2020 · Immunity
- Single-cell RNA sequencing reveals induction of distinct trained-immunity programs in human monocytesBowen Zhang, Simone J.C.F.M Moorlag, Jorge Dominguez-Andres, Ozlem Pinar Bulut, Gizem Kilic, Zhaoli Liu, Reinout van Crevel, Cheng-Jian Xu, Leo A.B. Joosten, Mihai Gheorghe Netea et al. · 2022 · Journal of Clinical Investigation
- Single-cell analysis reveals the chemotherapy-induced cellular reprogramming and novel therapeutic targets in relapsed/refractory acute myeloid leukemiaKening Li, Yuxin Du, Yun Cai, Wenjie Liu, Yan Lv, Bin Huang, Lishen Zhang, Zhi Wang, Ping Liu, Qian Sun et al. · 2022 · Leukemia
- THBS2 + cancer-associated fibroblasts promote EMT leading to oxaliplatin resistance via COL8A1-mediated PI3K/AKT activation in colorectal cancerXing Zhou, Jiashu Han, Anning Zuo, Yuhao Ba, Shutong Liu, Hui Xu, Yuyuan Zhang, Siyuan Weng, Zhaokai Zhou, Long Liu et al. · 2024 · Molecular Cancer
- Molecular mechanisms of lineage decisions in metabolite-specific T cellsFrancois P. Legoux, Jules Gilet, Emanuele Procopio, Klára Echasserieau, Karine Bernardeau, Olivier J Lantz · 2019 · Nature Immunology
- Single-cell RNA sequencing identifies an Il1rn+/Trem1+ macrophage subpopulation as a cellular target for mitigating the progression of thoracic aortic aneurysm and dissectionXuanyu Liu, Wen Chen, Guoyan Zhu, Hang Yang, Wenke Li, Mingyao Luo, Chang Shu, Zhou Zhou · 2022 · Cell Discovery
- Multimodal single-cell profiling of intrahepatic cholangiocarcinoma defines hyperactivated Tregs as a potential therapeutic targetGiorgia Alvisi, Alberto Termanini, Cristiana Soldani, Federica Portale, Roberta Carriero, Karolina Pilipow, Guido Costa, Michela Anna Polidoro, Barbara Franceschini, Ines Malenica et al. · 2022 · Journal of Hepatology
- Neoantigen-specific cytotoxic Tr1 CD4 T cells suppress cancer immunotherapyHussein Sultan, Yoshiko Takeuchi, Jeffrey P. Ward, Naveen Sharma, Tiantian Liu, Vladimir Sukhov, Maria M. Firulyova, Yuang Song, Samuel Ameh, Simone Brioschi et al. · 2024 · Nature
- Single-Cell Chromatin Analysis of Mammary Gland Development Reveals Cell-State Transcriptional Regulators and Lineage RelationshipsChi‐Yeh Chung, Zhibo Ma, Christopher Dravis, Sebastian Preißl, Olivier Poirion, Gidsela Luna, Xiaomeng Hou, Rajshekhar R. Giraddi, Bing Ren, Geoffrey M. Wahl · 2019 · Cell Reports
- A deep generative model for multi-view profiling of single-cell RNA-seq and ATAC-seq dataGaoyang Li, Shaliu Fu, Shuguang Wang, Chenyu Zhu, Bin Duan, Chen Tang, Xiaohan Chen, Guohui Chuai, Ping Q. Wang, Qi Liu · 2022 · Genome biology
- Integration Analysis of Single‐Cell Multi‐Omics Reveals Prostate Cancer HeterogeneityXiaojie Bian, Wenfeng Wang, Mierxiati Abudurexiti, Xingming Zhang, Weiwei Ma, Guohai Shi, Leilei Du, Midie Xu, Xin Wang, Cong Tan et al. · 2024 · Advanced Science
- Dysfunction of Hair Follicle Mesenchymal Progenitors Contributes to Age-Associated Hair LossWisoo Shin, Nicole L. Rosin, Holly D. Sparks, Sarthak Sinha, Waleed M Rahmani, Nilesh C. Sharma, Matt Workentine, Sepideh Abbasi, Elodie Labit, Jo Anne Stratton et al. · 2020 · Developmental Cell
- Single cell eQTL analysis identifies cell type-specific genetic control of gene expression in fibroblasts and reprogrammed induced pluripotent stem cellsDrew R. Neavin, Quan Hoang Nguyen, Maciej Daniszewski, Helena Hai Liang, Han Sheng Chiu, Yong Kiat Wee, Anne Senabouth, Samuel W. Lukowski, Duncan E. Crombie, Grace E. Lidgerwood et al. · 2021 · Genome biology
- Role of Calcium Signaling Pathway‐Related Gene Regulatory Networks in Ischemic Stroke Based on Multiple WGCNA and Single‐Cell AnalysisWeiwei Lin, Yangxin Wang, Yisheng Chen, Qiangwei Wang, Zhaowen Gu, Yongjian Zhu · 2021 · Oxidative Medicine and Cellular Longevity
- Medin co-aggregates with vascular amyloid-β in Alzheimer’s diseaseJessica Wagner, Karoline Degenhardt, Marleen Veit, Nikolaos N. Louros, Katerina Konstantoulea, Angelos Skodras, Katleen Wild, Ping Liu, Ulrike Obermüller, Vikas Bansal et al. · 2022 · Nature
- NADase CD38 is a key determinant of ovarian agingQingling Yang, Wenhui Chen, Luping Cong, Mengchen Wang, Hui Li, Huan Wang, Xiaoyan Luo, Jing Zhu, Xinxin Zeng, Zhenye Zhu et al. · 2023 · Nature Aging
- Two distinct epithelial-to-mesenchymal transition programs control invasion and inflammation in segregated tumor cell populationsKhalil Kass Youssef, Nitin P. Narwade, Aída Arcas, Ángel Márquez-Galera, Raúl Jiménez-Castaño, Cristina López-Blau, Hassan Fazilaty, David García-Gutierrez, Amparo Cano, Joan Galcerán et al. · 2024 · Nature Cancer
- MAP3K2-regulated intestinal stromal cells define a distinct stem cell nicheNingbo Wu, Hongxiang Sun, Xiaoyun Zhao, Yao Zhang, Jianmei Tan, Yuanyuan Qi, Qun Wang, Melissa Shu Feng Ng, Zhaoyuan Liu, Lingjuan He et al. · 2021 · Nature
- Single-cell transcriptome profiling reveals vascular endothelial cell heterogeneity in human skinQingyang Li, Zhenlai Zhu, Lei Wang, Yiting Lin, Hui Fang, Jie Lei, Tianyu Cao, Gang Wang, Erle Dang · 2021 · Theranostics
- A pan-tissue DNA methylation atlas enables in silico decomposition of human tissue methylomes at cell-type resolutionZhu, Tianyu, Liu, Jacklyn, Beck, Stephan, Pan, Sun, Capper, David, Lechner, Matt, Thirlwell, Chrissie, Breeze, Charles E., Teschendorff, Andrew E. · 2022 · Nature Methods
- Integrated single-cell transcriptomic analyses reveal that GPNMB-high macrophages promote PN-MES transition and impede T cell activation in GBMAizhen Xiong, Jiwei Zhang, Yan Chen, Yi Zhang, Fan Yang · 2022 · EBioMedicine
- A single-cell transcriptomic inventory of murine smooth muscle cellsLars Muhl, Giuseppe Mocci, Riikka S. Pietilä, Jianping Liu, Liqun He, Guillem Genové, Stefanos Leptidis, Sonja Gustafsson, Byambajav Buyandelger, Elisabeth Raschperger et al. · 2022 · Developmental Cell
- Single-cell transcriptomic analysis identifies murine heart molecular features at embryonic and neonatal stagesWei Hong Feng, Abha Singh Bais, Haoting He, Cassandra Rios, Shan Jiang, Juan Xu, Cindy A. Chang, Dennis Kostka, Guang Li · 2022 · Nature Communications
- Single-cell sequencing of ascites fluid illustrates heterogeneity and therapy-induced evolution during gastric cancer peritoneal metastasisXuanzhang Huang, Min-Jiao Pang, Jia-Yi Li, Hanyu Chen, Jingxu Sun, Yongxi Song, Hong-Jie Ni, Shi-Yu Ye, Shi Bai, Tenghui Li et al. · 2023 · Nature Communications
- Single-cell RNA sequencing reveals intratumoral heterogeneity in primary uveal melanomas and identifies HES6 as a driver of the metastatic diseaseCharlotte Pandiani, Thomas Strub, Nicolas Nottet, Yann Chéli, Giovanni Gambi, Karine Bille, Chrystel Husser, Mélanie Dalmasso, Guillaume E. Béranger, Sandra Lassalle et al. · 2021 · Cell Death and Differentiation
- Actuation enhances patterning in human neural tube organoidsAbdel Rahman Abdel Fattah, Brian Daza, Gregorius Rustandi, Miguel Ángel Berrocal-Rubio, Benjamin Gorissen, Suresh Kumar Poovathingal, Kristofer Davie, Jorge Barrasa Fano, Mar Cóndor, Xuanye Cao et al. · 2021 · Nature Communications
- Single‐cell profiles reveal distinctive immune response in atopic dermatitis in contrast to psoriasisBowen Zhang, Lennart Matthias Roesner, Stephan Traidl, Valerie A. C. M. Koeken, Cheng‐Jian Xu, Thomas Werfel, Yang Li · 2022 · Allergy
- Presence of onco-fetal neighborhoods in hepatocellular carcinoma is associated with relapse and response to immunotherapyZi-Yi Li, Rhea Pai, Saurabh Gupta, Jennifer Currenti, Wei Guo, A. Di Bartolomeo, Hao Feng, Zijie Zhang, Zhi-Zhen Li, Long-Qi Liu et al. · 2024 · Nature Cancer
- Single-cell and spatial analyses revealed the co-location of cancer stem cells and SPP1+ macrophage in hypoxic region that determines the poor prognosis in hepatocellular carcinomaGuangyu Fan, Tongji Xie, Lin Li, Le Tang, Xiaohong Han, Yuankai Shi · 2024 · npj Precision Oncology
- Integrating spatial and single-cell transcriptomics reveals tumor heterogeneity and intercellular networks in colorectal cancerJing Xiao, Xinyang Yu, Fanlin Meng, Yuncong Zhang, Wenbin Zhou, Yonghong Ren, Jingxia Li, Yimin Sun, Hongwei Sun, Guokai Chen et al. · 2024 · Cell Death and Disease
- Cellular plasticity balances the metabolic and proliferation dynamics of a regenerating liverChembazhi, Ullas V., Bangru, Sushant, Hernaez, Mikel, Kalsotra, Auinash · 2021 · Genome Research
- GRAND: a database of gene regulatory network models across human conditionsMarouen Ben Guebila, Camila M. Lopes‐Ramos, Deborah A. Weighill, Abhijeet R. Sonawane, Rebekka Burkholz, Behrouz Shamsaei, John Platig, Kimberly Glass, Marieke L. Kuijjer, John F Quackenbush · 2021 · Nucleic Acids Research
- Integrated profiling of human pancreatic cancer organoids reveals chromatin accessibility features associated with drug sensitivityXiaohan Shi, Yunguang Li, Qiuyue Yuan, Shijie Tang, Shiwei Guo, Yehan Zhang, Juan He, Xiaoyu Zhang, Ming Han, Zhuang Liu et al. · 2022 · Nature Communications
- Pan-cancer profiling of tumor-infiltrating natural killer cells through transcriptional reference mappingHerman Netskar, Aline Pfefferle, Jodie P. Goodridge, Ebba Sohlberg, Olli Dufva, Sarah Amalia Teichmann, Demi Brownlie, Jakob Michaëlsson, Nicole Marquardt, Trevor Clancy et al. · 2024 · Nature Immunology
- Single-cell and bulk transcriptomics of the liver reveals potential targets of NASH with fibrosisWang, Zhong-Yi, Keogh, Adrian, Waldt, Annick, Cuttat, Rachel, Neri, Marilisa, Zhu, Shanshan, Schuierer, Sven, Ruchti, Alexandra, Crochemore, Christophe, Knehr, Judith et al. · 2021 · Scientific Reports
- Single Cell and Single Nucleus RNA-Seq Reveal Cellular Heterogeneity and Homeostatic Regulatory Networks in Adult Mouse Stria VascularisSoumya Korrapati, Ian Taukulis, Rafal T. Olszewski, Madeline P. Pyle, Shoujun Gu, Riya Singh, Carla Griffiths, Daniel Martı́n, Erich T. Boger, Robert J. Morell et al. · 2019 · Frontiers in Molecular Neuroscience
- Single-cell atlas of keratoconus corneas revealed aberrant transcriptional signatures and implicated mechanical stretch as a trigger for keratoconus pathogenesisShengqian Dou, Qun Wang, Bin Zhang, Chao Wei, Huijun Wang, Ting Liu, Haoyun Duan, Hui Jiang, Mingna Liu, Xiaolin Qi et al. · 2022 · Cell Discovery
- Dynamic regulation of tissue fluidity controls skin repair during wound healingRahul M. Sarate, Joel Hochstetter, Manon Valet, Adrien Hallou, Yura Song, Nordin Bansaccal, Melanie Ligare, Mariaceleste Aragona, Dan Engelman, Anaïs Bauduin et al. · 2024 · Cell
- Generative adversarial networks simulate gene expression and predict perturbations in single cellsArsham Ghahramani, Fiona M. Watt, Nicholas M. Luscombe · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
- Single cell RNA sequencing identifies an early monocyte gene signature in acute respiratory distress syndromeYale Jiang, Brian R. Rosborough, Jie Chen, Sudipta Das, Georgios D. Kitsios, Bryan J. McVerry, Rama K. Mallampalli, Janet S. Lee, Anuradha Ray, Wei Chen et al. · 2020 · JCI Insight
- Single-cell RNA-seq unravels alterations of the human spermatogonial stem cell compartment in patients with impaired spermatogenesisSara Di Persio, Tobias Tekath, Lara Marie Siebert-Kuss, Jann‐Frederik Cremers, Joachim Wistuba, Xiaolin Li, Gerd Meyer zu Hörste, Hannes C. A. Drexler, Margot Julia Wyrwoll, Frank Tüttelmann et al. · 2021 · Cell Reports Medicine
- Multi-omic evaluation of metabolic alterations in multiple sclerosis identifies shifts in aromatic amino acid metabolismKathryn C. Fitzgerald, Matthew D. Smith, Sol Kim, Elias S. Sotirchos, Michael D. Kornberg, Morgan Douglas, Bardia Nourbakhsh, Jennifer S. Graves, Ramandeep Rattan, Laila Poisson et al. · 2021 · Cell Reports Medicine
- Cell-fate transition and determination analysis of mouse male germ cells throughout developmentJiexiang Zhao, Ping Lü, Cong Wan, Yaping Huang, Manman Cui, Xinyan Yang, Yuqiong Hu, Yi Zheng, Ji Dong, Mei Wang et al. · 2021 · Nature Communications
- Guidelines for bioinformatics of single-cell sequencing data analysis in Alzheimer’s disease: review, recommendation, implementation and applicationMinghui Wang, Won‐Min Song, Ming Chen, Qian Wang, Xianxiao Zhou, Peng Xu, Azra Krek, Yonejung Yoon, Lap Ho, Miranda E. Orr et al. · 2022 · Molecular Neurodegeneration
- Single-nucleus RNA-sequencing of autosomal dominant Alzheimer disease and risk variant carriersLogan Brase, Shih‐Feng You, Ricardo D’Oliveira Albanus, Jorge L. Del‐Aguila, Yaoyi Dai, Brenna C. Novotny, Carolina Soriano‐Tárraga, Taitea Dykstra, María Victoria Fernández, John Budde et al. · 2023 · Nature Communications
- Identifying CNS-colonizing T cells as potential therapeutic targets to prevent progression of multiple sclerosisMax Kaufmann, Hayley G. Evans, Anna-Lena Schaupp, Jan Broder Engler, Gurman Kaur, Anne Willing, Nina Kursawe, Charlotte Schubert, Kathrine E. Attfield, Lars H. Fugger et al. · 2021 · Med
- Expression characteristics of interferon-stimulated genes and possible regulatory mechanisms in lupus patients using transcriptomics analysesYiyao Deng, Ying Zheng, Delun Li, Quan Hong, Min Zhang, Qinggang Li, Bo Fu, Lingling Wu, Xu Wang, Wanjun Shen et al. · 2021 · EBioMedicine
- Systematic discovery and perturbation of regulatory genes in human T cells reveals the architecture of immune networksJacob W. Freimer, Oren Shaked, Sahin Naqvi, Nasa Sinnott-Armstrong, Arwa S. Kathiria, Christian M. Garrido, Amy F. Chen, Jessica T. Cortez, William James Greenleaf, Jonathan K. Pritchard et al. · 2022 · Nature Genetics
- The CD58-CD2 axis is co-regulated with PD-L1 via CMTM6 and shapes anti-tumor immunityPatricia Ho, Johannes C. Melms, Meri Rogava, Chris J. Frangieh, Joanna Poźniak, Shivem B. Shah, Zachary H. Walsh, Oleksandr Kyrysyuk, Amit Dipak Amin, Lindsay Caprio et al. · 2023 · Cancer Cell
- Response to tumor-infiltrating lymphocyte adoptive therapy is associated with preexisting CD8 + T-myeloid cell networks in melanomaDavid Barras, Eleonora Ghisoni, Johanna Chiffelle, Angela Orcurto, Julien Dagher, Noémie Fahr, Fabrizio Benedetti, Isaac Crespo, Alizée J Grimm, Matteo Morotti et al. · 2024 · Science Immunology
- Network Medicine in PathobiologyLee, Laurel Yong-Hwa, Loscalzo, Joseph · 2019 · The American Journal of Pathology
- EZH1 repression generates mature iPSC-derived CAR T cells with enhanced antitumor activityRan Jing, Irene Scarfò, Mohamad Ali Toufic Najia, Edroaldo Lummertz da Rocha, Areum Han, Michael Sanborn, Trevor Bingham, Caroline Kubaczka, Deepak K. Jha, Marcelo Falchetti et al. · 2022 · Cell stem cell
- Data analysis guidelines for single-cell RNA-seq in biomedical studies and clinical applicationsMin‐Ying Su, Tao Pan, Qiu-Zhen Chen, Weiwei Zhou, Yi Gong, Gang Xu, Huan-Yu Yan, Si Li, Qiao-Zhen Shi, Ya Zhang et al. · 2022 · Military Medical Research
- Asymmetric gene expression and cell-type-specific regulatory networks in the root of bread wheat revealed by single-cell multiomics analysisLihua Zhang, Chao He, Yuting Lai, Yating Wang, Lu Kang, Ankui Liu, Caixia Lan, Handong Su, Yuwen Gao, Zeqing Li et al. · 2023 · Genome biology
- Mature tertiary lymphoid structures evoke intra-tumoral T and B cell responses via progenitor exhausted CD4+ T cells in head and neck cancerHao Li, Meng-Jie Zhang, Boxin Zhang, Wen‐Ping Lin, Shu‐Jin Li, Dian Xiong, Qing Wang, Wen-Da Wang, Qi‐Chao Yang, Cong‐Fa Huang et al. · 2025 · Nature Communications
- Selective remodelling of the adipose niche in obesity and weight lossAntonio M. A. Miranda, Liam McAllan, Guianfranco Mazzei, Ivan Andrew, Iona Davies, Meryem Sebla Ertuğrul, Julia S. Kenkre, Hiromi Kudo, Joana Carrelha, Bhavik Patel et al. · 2025 · Nature
- Single-cell transcriptome profiling of the vaginal wall in women with severe anterior vaginal prolapseYaqian Li, Qingyang Zhang, Baofa Sun, Yidi Ma, Ye Zhang, Min Wang, Congcong Ma, Honghui Shi, Zhijing Sun, Juan Chen et al. · 2021 · Nature Communications
- ANANSE: an enhancer network-based computational approach for predicting key transcription factors in cell fate determinationQuan Xu, Γεώργιος Γεωργίου, Siebren Frölich, Maarten van der Sande, Gert Jan C. Veenstra, Huiqing Zhou, Simon J. van Heeringen · 2021 · Nucleic Acids Research
- Cancer-selective metabolic vulnerabilities in MYC-amplified medulloblastomaWilliam D. Gwynne, Yujin Suk, Stefan Custers, Nicholas Mikolajewicz, Jeremy K. Chan, Zsolt E. Zador, Shawn C. Chafe, Kui Zhai, Laura Escudero, Cunjie Zhang et al. · 2022 · Cancer Cell
- Rituximab-resistant splenic memory B cells and newly engaged naive B cells fuel relapses in patients with immune thrombocytopeniaÉtienne Crickx, Pascal Chappert, Aurélien Sokal, Sandra Weller, Imane Azzaoui, Alexis Vandenberghe, Guillaume Bonnard, Geoffrey Rossi, Tatiana Fadeev, Sébastien Storck et al. · 2021 · Science Translational Medicine
- Mitochondria-ER contact mediated by MFN2-SERCA2 interaction supports CD8 + T cell metabolic fitness and function in tumorsJiefeng Yang, Xudong Xing, Li Luo, Xinwei Zhou, Jian-Xiong Feng, Kangbo Huang, Huashan Liu, Shanzhao Jin, Yi-Na Liu, Shi-Hui Zhang et al. · 2023 · Science Immunology
- Nicotinamide metabolism face-off between macrophages and fibroblasts manipulates the microenvironment in gastric cancerYu Jiang, Yawen Wang, Guofeng Chen, Fei Sun, Qijing Wu, Qiong Huang, Dongqiang Zeng, Wenjun Qiu, Jiao Wang, Zhiqi Yao et al. · 2024 · Cell Metabolism
- A single nuclear transcriptomic characterisation of mechanisms responsible for impaired angiogenesis and blood-brain barrier function in Alzheimer’s diseaseTsartsalis, Stergios, Sleven, Hannah, Fancy, Nurun, Wessely, Frank, Smith, Amy M., Willumsen, Nanet, Cheung, To Ka Dorcas, Rokicki, Michal J., Chau, Vicky, Ifie, Eseoghene et al. · 2024 · Nature Communications
- P-TEFb Activation by RBM7 Shapes a Pro-survival Transcriptional Response to Genotoxic StressAndrii Bugai, Alexandre J.C. Quaresma, Caroline C. Friedel, Tina Lenasi, Robert Düster, Christopher R. Sibley, Koh Fujinaga, Petra Kukanja, Thomas Hennig, Melanie Blasius et al. · 2019 · Molecular Cell
- Single-cell RNA-seq reveals developmental plasticity with coexisting oncogenic states and immune evasion programs in ETP-ALLPraveen Anand, Amy Guillaumet-Adkins, Valeriya Dimitrova, Huiyoung Yun, Yotam Drier, Noori Sotudeh, Anna J. Rogers, Madhu Micheal Ouseph, Monica S. Nair, Sayalee V. Potdar et al. · 2020 · Blood
- Expression of Immune Related Genes and Possible Regulatory Mechanisms in Alzheimer’s DiseaseYanjun Lu, Ke Li, Yu Hu, Xiong Wang · 2021 · Frontiers in Immunology
- Single‐cell transcriptomics of LepR‐positive skeletal cells reveals heterogeneous stress‐dependent stem and progenitor poolsChunyang Mo, Jingxin Guo, Jiachen Qin, Xiaoying Zhang, Yuxi Sun, Hanjing Wei, Dandan Cao, Yiying Zhang, Chengchen Zhao, Yanhong Xiong et al. · 2021 · The EMBO Journal
- Lineage-specific regulatory changes in hypertrophic cardiomyopathy unraveled by single-nucleus RNA-seq and spatial transcriptomicsXuanyu Liu, Kunlun Yin, Liang Chen, Wen Chen, Wenke Li, Taojun Zhang, Yang Sun, Meng Yuan, Hongyue Wang, Yunhu Song et al. · 2023 · Cell Discovery
- Integrated Analysis Highlights the Immunosuppressive Role of TREM2+ Macrophages in Hepatocellular CarcinomaZhou, Lisha, Wang, Meiling, Guo, Hanrui, Hou, Jun, Zhang, Yingna, Li, Man, Wu, Xiangwei, Chen, Xueling, Wang, Lianghai · 2022 · Frontiers in Immunology
- Network inference in systems biology: recent developments, challenges, and applicationsMichael Saint-Antoine, Abhyudai Singh · 2020 · Current Opinion in Biotechnology
- Spatiotemporal Dynamics of the Molecular Expression Pattern and Intercellular Interactions in the Glial Scar Response to Spinal Cord InjuryLeilei Gong, Yun Gu, Xiaoxiao Han, Chengcheng Luan, Chang Liu, Xinghui Wang, Yufeng Sun, Mengru Zheng, Mengya Fang, Shuhai Yang et al. · 2022 · Neuroscience Bulletin
- Cellular recovery after prolonged warm ischaemia of the whole bodyDavid Andrijević, Zvonimir Vrselja, Taras Lysyy, Shupei Zhang, Mario Škarica, Ana Spajic, David Dellal, Stephanie Thorn, Robert B. Duckrow, Shaojie Ma et al. · 2022 · Nature
- A differentiation roadmap of murine placentation at single-cell resolutionXiangxiang Jiang, Yue Wang, Zhenyu Xiao, Yan Long, Shanshan Guo, Yiming Wang, Hao Wu, Xuehan Zhao, Xiaoyin Lu, Hongmei Wang · 2023 · Cell Discovery
- Impact of constitutional TET2 haploinsufficiency on molecular and clinical phenotype in humansKaasinen, Eevi, Kuismin, Outi, Rajamäki, Kristiina, Ristolainen, Heikki, Aavikko, Mervi, Kondelin, Johanna, Saarinen, Silva, Berta, Davide G., Katainen, Riku, Hirvonen, Elina A. M. et al. · 2019 · Nature Communications
- Single-cell Transcriptome Profiling reveals Dermal and Epithelial cell fate decisions during Embryonic Hair Follicle DevelopmentWei Ge, Shao‐Jing Tan, Shan-He Wang, Lan Li, Xiao-Feng Sun, Wei Shen, Xin Wang · 2020 · Theranostics
- Tracing cell-type evolution by cross-species comparison of cell atlasesJingjing Wang, Huiyu Sun, Mengmeng Jiang, Jiaqi Li, Peijing Zhang, Haide Chen, Yuqing Mei, Lijiang Fei, Shujing Lai, Xiaoping Han et al. · 2021 · Cell Reports
- Single‐cell transcriptomics reveal temporal dynamics of critical regulators of germ cell fate during mouse sex determinationChloé Mayère, Yasmine Neirijnck, Pauline Sararols, Chris M. Rands, Isabelle Stévant, Françoise Kühne, Anne‐Amandine Chassot, Marie‐Christine Chaboissier, Emmanouil T. Dermitzakis, Serge Nef · 2021 · The FASEB Journal
- Limited access to antigen drives generation of early B cell memory while restraining the plasmablast responseVassilis Glaros, René Rauschmeier, Artem V. Artemov, Annika Reinhardt, Sebastian Ols, Aikaterini Emmanouilidi, Charlotte Gustafsson, Yuanyuan You, Claudio Mirabello, Åsa K. Björklund et al. · 2021 · Immunity
- Comprehensive investigations revealed consistent pathophysiological alterations after vaccination with COVID-19 vaccinesJiping Liu, Junbang Wang, Jinfang Xu, Han Xia, Yue Wang, Chunxue Zhang, Wei Chen, Huina Zhang, Qi Liu, Rong Zhu et al. · 2021 · Cell Discovery
- A growth factor–expressing macrophage subpopulation orchestrates regenerative inflammation via GDF-15Andreas Patsalos, László Halász, Miguel A. Medina-Serpas, Wilhelm K. Berger, Bence Dániel, Petros Tzerpos, Máté Kiss, Gergely Nagy, Cornelius Fischer, Zoltán Simándi et al. · 2021 · The Journal of Experimental Medicine
- Dissecting the Single-Cell Transcriptome Network of Immune Environment Underlying Cervical Premalignant Lesion, Cervical Cancer and Metastatic Lymph NodesChunbo Li, Keqin Hua · 2022 · Frontiers in Immunology
- Single cell multi-omics reveal intra-cell-line heterogeneity across human cancer cell linesQionghua Zhu, Xin Zhao, Yuanhang Zhang, Yanping Li, Shang Liu, Jingxuan Han, Zhiyuan Sun, Chunqing Wang, Daqi Deng, Yisen Tang et al. · 2023 · Nature Communications
- Patterning and folding of intestinal villi by active mesenchymal dewettingTyler R. Huycke, Teemu J. Häkkinen, Hikaru Miyazaki, Vasudha Srivastava, Emilie Barruet, Christopher S. McGinnis, Ali Kalantari, Jake Cornwall-Scoones, Dedeepya Vaka, Qin Zhu et al. · 2024 · Cell
- Contrasting cytotoxic and regulatory T cell responses underlying distinct clinical outcomes to anti-PD-1 plus lenvatinib therapy in cancerGuo, Xinyi, Nie, Hu, Zhang, Wenwen, Li, Jiesheng, Ge, Jing, Xie, Bowen, Hu, Wenbo, Zhu, Yicheng, Zhong, Na, Zhang, Xinmei et al. · 2025 · Cancer Cell
- Defining the Design Principles of Skin Epidermis Postnatal GrowthSophie Dekoninck, Édouard Hannezo, Alejandro Sifrim, Yekaterina A. Miroshnikova, Mariaceleste Aragona, Milan Malfait, Souhir Gargouri, Charlotte de Neunheuser, Christine Dubois, Thierry Voet et al. · 2020 · Cell
- Single-Cell RNA Sequencing Reveals Heterogeneity of Vascular Cells in Early Stage Murine Abdominal Aortic Aneurysm—Brief ReportHuan Yang, Ting Zhou, Amelia Stranz, Elise DeRoo, Bo Liu · 2021 · Arteriosclerosis Thrombosis and Vascular Biology
- Single-cell analyses highlight the proinflammatory contribution of C1q-high monocytes to Behçet’s diseaseWenjie Zheng, Xiaoman Wang, Jinjing Liu, Xin Yu, Li Lu, Heping Wang, Jijun Yu, Xiaoya Pei, Chaoran Li, Zhimian Wang et al. · 2022 · Proceedings of the National Academy of Sciences