Corollary discharge circuits for saccadic modulation of the pigeon visual system
Abstract
A saccadic eye movement causes a variety of transient perceptual sequelae that might be the results of corollary discharge. Here we describe the neural circuits for saccadic corollary discharge that modulates activity throughout the pigeon visual system. Saccades in pigeons caused inhibition that was mediated by corollary discharge followed by enhancement of firing activity in the telencephalic hyperpallium, visual thalamus and pretectal nucleus lentiformis mesencephali (nLM) with opposite responses in the accessory optic nucleus (nBOR). Inactivation of thalamic neurons eliminated saccadic responses in telencephalic neurons, and inactivation of both the nLM and the nBOR abolished saccadic responses in thalamic neurons. Saccade-related omnipause neurons in the brainstem raphe complex inhibited the nBOR and excited the nLM, whereas inactivation of raphe neurons eliminated saccadic responses in both optokinetic and thalamic neurons. It seems that saccadic responses in telencephalic neurons are generated by corollary discharge signals from brainstem neurons that are transmitted through optokinetic and thalamic neurons. These signals might have important roles in visual perception.
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Saccadic suppression mechanisms have been identified in pigeons, chickens, locusts, monkeys and cats.
“Saccadic suppression mechanisms have been identified in a host of different species, such as pigeons, chickens, locusts, monkeys and cats34–38.”
From Corollary discharge across the animal kingdom (2008) · cites this paper as [38]
To date, only a few large-scale circuit-level investigations of corollary discharge that combined behaviour with physiology have been performed.
“To date, only a few large-scale circuit-level investigations of CD that combined behaviour with physiology have been performed38,40.”
From Corollary discharge across the animal kingdom (2008) · cites this paper as [38]
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- Authors
- Yang, Y., Cao, P., Yang, Y., & Wang, S.-R.
- Affiliations
- Chinese Academy of Sciences (CN)
- Corresponding author
- Wang, Shu-Rong
- Venue
- Nature Neuroscience
- Published
- 2008-04-06
- Volume
- 11
- Issue
- 5
- Pages
- 595-602
- ISSN
- 1097-6256 (ISSN-L)
- 1546-1726
- OpenAlex
- W2121716359
- Cited by
- 41
- References
- 48
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 1 · 2023: 2 · 2022: 1 · 2021: 3 · 2020: 5 · 2019: 2 · 2018: 3 · 2016: 1 · 2015: 2 · 2014: 1 · 2013: 1 · 2012: 1
- FWCI
- 2.41
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Natural Science Foundation of China
- University of California, San Francisco
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Multisensory perception and integration
- Life Sciences › Neuroscience › Cognitive Neuroscience › Motor Control and Adaptation
- Keywords
- corollary discharge, saccades, visual thalamus, omnipause neurons, optokinetic response, neural circuits, visual perception, thalamic inhibition
- MeSH terms
- Animals, Brain, Female, Male, Motion Perception, Neural Inhibition, Neurons, Orientation, Photic Stimulation, Columbidae, Psychomotor Performance, Raphe Nuclei, Saccades, Space Perception, Species Specificity, Superior Colliculi, Telencephalon, Thalamus, Visual Pathways, Nystagmus, Optokinetic
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