The DOI matches its Crossref record; 51 of the 51 references it cites were found in a registry or an index.
A critical period for auditory thalamocortical connectivity
Open accessAbstract
Neural circuits are shaped by experience during periods of heightened brain plasticity in early postnatal life. Exposure to acoustic features produces age-dependent changes through largely unresolved cellular mechanisms and sites of origin. We isolated the refinement of auditory thalamocortical connectivity by in vivo recordings and day-by-day voltage-sensitive dye imaging in an acute brain slice preparation. Passive tone-rearing modified response strength and topography in mouse primary auditory cortex (A1) during a brief, 3-d window, but did not alter tonotopic maps in the thalamus. Gene-targeted deletion of a forebrain-specific cell-adhesion molecule (Icam5) accelerated plasticity in this critical period. Consistent with its normal role of slowing spinogenesis, loss of Icam5 induced precocious stubby spine maturation on pyramidal cell dendrites in neocortical layer 4 (L4), identifying a primary locus of change for the tonotopic plasticity. The evolving postnatal connectivity between thalamus and cortex in the days following hearing onset may therefore determine a critical period for auditory processing.
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“Thus, one striking implication is that the choroid plexus, via the CSF, may be a general regulator of CP plasticity, including the amygdala (Gogolla et al., 2009), auditory (Barkat et al., 2011) or prefrontal cortex (Belforte et al., 2010; Yang et al., 2012) – structures with shifted or shorter critical periods than V1.”
From Choroid-Plexus-Derived Otx2 Homeoprotein Constrains Adult Cortical Plasticity (2013) · cites this paper as Barkat et al., 2011
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Critical period plasticity in local cortical circuits
Hensch, T. K. (2005) · Nature Reviews Neuroscience · doi:10.1038/nrn1787 · Cited by 2,323
Self-citationWiesel, T. N., & Hubel, D. H. (1965) · Journal of Neurophysiology · doi:10.1152/jn.1965.28.6.1029 · Cited by 1,598
Hensch, T. K. (2004) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.27.070203.144327 · Cited by 1,300
Self-citationResponse properties of vibrissa units in rat SI somatosensory neocortex
Simons, D. J. (1978) · Journal of Neurophysiology · doi:10.1152/jn.1978.41.3.798 · Cited by 780
Allendoerfer, K. L., & Shatz, C. J. (1994) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.17.030194.001153 · Cited by 653
VSDI: a new era in functional imaging of cortical dynamics
Grinvald, A., & Hildesheim, R. (2004) · Nature Reviews Neuroscience · doi:10.1038/nrn1536 · Cited by 618
Ferezou, I., Bolea, S., & Petersen, C. C. H. (2006) · Neuron · doi:10.1016/j.neuron.2006.03.043 · Cited by 466
The subplate and early cortical circuits
Kanold, P. O., & Luhmann, H. J. (2010) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-060909-153244 · Cited by 440
Petersen, C. C. H., Grinvald, A., & Sakmann, B. J. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-04-01298.2003 · Cited by 427
Werker, J. F., & Tees, R. C. (2005) · Developmental Psychobiology · doi:10.1002/dev.20060 · Cited by 394
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Adolescence as a neurobiological critical period for the development of higher-order cognition
Larsen, B., & Luna, B. (2018) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2018.09.005 · Cited by 853
The Cerebellum, Sensitive Periods, and Autism
Wang, S. S. ‐., Kloth, A. D., & Badura, A. (2014) · Neuron · doi:10.1016/j.neuron.2014.07.016 · Cited by 866
Critical periods in speech perception: New directions
Werker, J. F., & Hensch, T. K. (2015) · Annual Review of Psychology · doi:10.1146/annurev-psych-010814-015104 · Cited by 774
Self-citationPreventive strategies for mental health
Arango, C., Díaz-Caneja, C. M., McGorry, P. D., Rapoport, J., Sommer, I. E., Vorstman, J. A., McDaid, D., Marín, O., Serrano-Drozdowskyj, E., Freedman, R., et al. (2018) · The Lancet Psychiatry · doi:10.1016/s2215-0366(18)30057-9 · Cited by 1,271
Balancing Plasticity/Stability Across Brain Development
Takesian, A. E., & Hensch, T. K. (2013) · Progress in Brain Research · doi:10.1016/b978-0-444-63327-9.00001-1 · Cited by 667
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Metadata
- Authors
- Barkat, T. R., Polley, D. B., & Hensch, T. K.
- Affiliations
- Harvard University (US)
- Massachusetts Eye and Ear Infirmary (US)
- Corresponding author
- Hensch, Takao K
- Venue
- Nature Neuroscience
- Published
- 2011-07-31
- Volume
- 14
- Issue
- 9
- Pages
- 1189-1194
- ISSN
- 1097-6256 (ISSN-L)
- 1546-1726
- PMC
- PMC3419581
- OpenAlex
- W2048549637
- Cited by
- 252
- References
- 51
- Citations by year
- 2026: 9 · 2025: 23 · 2024: 11 · 2023: 7 · 2022: 8 · 2021: 21 · 2020: 18 · 2019: 18 · 2018: 20 · 2017: 21 · 2016: 11 · 2015: 18 · 2014: 16 · 2013: 31 · 2012: 17
- FWCI
- 10.87
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- U.S. Public Health Service (009836)
- National Institute on Deafness and Other Communication Disorders (R01DC009836)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neuroscience and Music Perception
- Life Sciences › Neuroscience › Sensory Systems › Hearing, Cochlea, Tinnitus, Genetics
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Keywords
- critical period, auditory plasticity, primary auditory cortex, tonotopic map, ICAM-5, adhesion molecules, dendritic spine maturation, spinogenesis, thalamus, postnatal development, mice
- MeSH terms
- Acoustic Stimulation, Action Potentials, Age Factors, Amino Acids, Analysis of Variance, Animals, Animals, Newborn, Auditory Cortex, Auditory Pathways, Auditory Perception, Critical Period, Psychological, Evoked Potentials, Auditory, Membrane Glycoproteins, Nerve Tissue Proteins, Sound, Thalamus, Patch-Clamp Techniques, Mice, In Vitro Techniques
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