CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology
The Alzheimer Disease Neuroimaging Initiative, Bradshaw, Elizabeth M, Chibnik, Lori B, Keenan, Brendan T, Ottoboni, Linda, Raj, Towfique, Tang, Anna, Rosenkrantz, Laura L, Imboywa, Selina, Lee, Michelle, Von Korff, Alina, Morris, Martha C, Evans, Denis A, Johnson, Keith, Sperling, Reisa A, Schneider, Julie A, Bennett, David A, De Jager, Philip L·2013·Nature Neuroscience
DOI 10.1038/nn.3435
Cited by (571)
Items 401–500 of 571
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- CD33 Ameliorates Surgery-Induced Spatial Learning and Memory Impairments Through TREM2Jie Zou, Yaxuan Wang, Xinyue Zhang, Xue Pan, Te Fang, Dasheng Cai, Lili Guo, Yu Li, Yi He, Xuezhao Cao · 2024 · Molecular Neurobiology
- Effects of CD33 Variants on Neuroimaging Biomarkers in Non-Demented EldersYajuan Wang, Alzheimer’s Disease Neuroimaging Initiative, Yu Wan, Hui-Fu Wang, Chen‐Chen Tan, Jieqiong Li, Jin‐Tai Yu, Lan Tan · 2019 · Journal of Alzheimer s Disease
- The CD33 genotype associated cognitive performance was bidirectionally modulated by intrinsic functional connectivity in the Alzheimer’s disease spectrumLiang Gong, Ronghua Xu, Lin Lan, Duan Liu, Jie Shen, Bei Zhang · 2019 · Biomedicine & Pharmacotherapy
- Alzheimer’s Disease Risk Variant rs3865444 in the CD33 Gene: A Possible Role in Susceptibility to Multiple SclerosisJuraj Javor, Mária Bucová, Vladimı́ra Ďurmanová, Dominika Radošinská, Zuzana Párnická, Daniel Čierný, Egon Kurča, Daniela Čopíková‐Cudráková, Karin Gmitterová, Ivana Shawkatová · 2022 · Life
- Association of CD33 rs3865444:C˃A polymorphism with a reduced risk of late‐onset Alzheimer's disease in Slovaks is limited to subjects carrying the APOE ε4 alleleJuraj Javor, Vladimı́ra Ďurmanová, Zuzana Párnická, Gabriel Minárik, Mária Králová, Ján Pečeňák, Barbora Vašečková, Veronika Režnáková, Stanislav Šutovský, Karin Gmitterová et al. · 2020 · International Journal of Immunogenetics
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- The Genetic Basis of Alzheimer’s DiseaseBasavaraj V. Hooli, Rudolph E. Tanzi · 2016 · Elsevier eBooks
- Pseudogene-Mediated Gene Conversion After CRISPR-Cas9 Editing Demonstrated by Partial CD33 Conversion with SIGLEC22PBenjamin C. Shaw, Steven Estus · 2021 · The CRISPR Journal
- A Common Haplotype Lowers PU.1 Expression in Myeloid Cells and Delays Onset of Alzheimer's DiseaseHuang, Kuan-lin, Marcora, Edoardo, Pimenova, Anna A, Di Narzo, Antonio F, Kapoor, Manav, Jin, Sheng Chih, Harari, Oscar, Bertelsen, Sarah, Fairfax, Benjamin P, Czajkowski, Jake et al. · 2017
- The Role of Genetics in Alzheimer's Disease and Parkinson's DiseaseTenielle Porter, Aleksandra Gozt, Francis L. Mastaglia, Simon Matthew Laws · 2019 · Wiley eBooks
- Interplay between CD33 and TREM2 in Alzheimer’s Disease: Potential Mechanistic Insights into Microglial Function in Amyloid PathologyElizabeth Toyin Akinluyi, Kei Takahashi, Meghan G. Connolly, Wayne W. Poon, Matthew Scott Macauley · 2025 · ACS Chemical Neuroscience
- Genetic causal relationship between multiple immune cell phenotypes and Parkinson’s disease: a two-sample bidirectional Mendelian randomization studyHong Chen, Wang Xie, Ze Chang, Juan Zhang, Daojun Xie · 2024 · Journal of Neurophysiology
- Scopoletin Ameliorates Lipopolysaccharide Induced Neuroinflammation, Oxidative Stress and Cognitive Dysfunction in Mice: A Mechanistic StudyMalvika Gursahani, Nitin Bhanudas Gawali, Sarayu Arvind Pai, Snehal Nitin Mestry, Archana Ramesh Juvekar · 2021 · Journal of Pharmaceutical Research International
- Druggable targets for the immunopathy of Alzheimer's diseaseDonald Fredric Weaver · 2023 · RSC Medicinal Chemistry
- Association between Alzheimer’s disease genes and trajectories of cognitive function decline in Han Chinese in TaiwanTsung-Jen Hsieh, Alzheimer’s Disease Neuroimaging Initiative, Wei‐Ju Lee, Yi‐Chu Liao, Chih‐Cheng Hsu, Yao‐Hwei Fang, Tzu‐Yu Chen, Yung‐Shuan Lin, I‐Shou Chang, Shuu‐Jiun Wang et al. · 2021 · Aging
- Can MRI T1 be used to detect early changes in 5xFAD Alzheimer’s mouse brain?Nicholas G. Spencer, David Paul Lovell, Kay Elderfield, Brian Austen, Franklyn A. Howe · 2016 · Magnetic Resonance Materials in Physics Biology and Medicine
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- Intracerebral inoculation of healthy non-transgenic rats with a single aliquot of oligomeric amyloid-β (1–42) profoundly and progressively alters brain function throughout lifeMarco Krämer, Thu‐Huong Hoang, Honghong Yang, Olena Shchyglo, Juliane Böge, Ute Neubacher, Jens Colitti-Klausnitzer, Denise Manahan‐Vaughan · 2024 · Frontiers in Aging Neuroscience
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- The role of immunity and neuroinflammation in genetic predisposition and pathogenesis of Alzheimer’s diseaseSeoyoung Yoon, Yong‐Ku Kim · 2015 · Global Medical Genetics
- Mitochondria at the Base of Neuronal Innate Immunity in Alzheimer’s and Parkinson’s DiseasesA. Raquel Esteves, Diana Filipa Silva, Daniel Santos, Emanuel Candeias, Filipa Filipe, Sandra M. Cardoso · 2018 · InTech eBooks
- Amyloid-beta and tau pathologies act synergistically to induce novel disease stage-specific microglia subtypesDong Won Kim, Kevin J. Tu, Alice Wei, Ashley Lau, Anabel Gonzalez-Gil, Tiaoyu Cao, Kerstin E. Braunstein, Jonathan P. Ling, Juan Carlos Troncoso, Philip C. Wong et al. · 2022 · Research Square
- CD33-CD45 Interaction Reveals a Mechanistic Link to Alzheimer’s Disease SusceptibilityNicole Vo, Cory D. Rillahan, Zena K. Chatila, Daniel M. Virga, Jennifer L. Hall, Kirstin A. Tamucci, Mamunur Rashid, Sarah M. Connor, Sana Chintamen, Gaelen Guzman et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
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