Regulation of aversion to noxious food by Drosophila neuropeptide Y– and insulin-like systems

Optimal foraging, the marginal value theorem

Charnov, E. L. (1976) · Theoretical Population Biology · doi:10.1016/0040-5809(76)90040-x · Cited by 5,374

Role of Brain Insulin Receptor in Control of Body Weight and Reproduction

Brüning, J. C., Gautam, D., Burks, D. J., Gillette, J., Schubert, M., Orban, P. C., Klein, R., Krone, W., Müller-Wieland, D., & Kahn, C. R. (2000) · Science · doi:10.1126/science.289.5487.2122 · Cited by 2,235

An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control

Brogiolo, W., Stocker, H., Ikeya, T., Rintelen, F., Fernandez, R., & Hafen, E. (2001) · Current Biology · doi:10.1016/s0960-9822(01)00068-9 · Cited by 1,255

Ablation of Insulin-Producing Neurons in Flies: Growth and Diabetic Phenotypes

Rulifson, E. J., Kim, S. K., & Nusse, R. (2002) · Science · doi:10.1126/science.1070058 · Cited by 1,064

A nutrient sensor mechanism controls Drosophila growth

Colombani, J., Raisin, S., Pantalacci, S., Radimerski, T., Montagne, J., & Léopold, P. (2003) · Cell · doi:10.1016/s0092-8674(03)00713-x · Cited by 809

Nutrient-Dependent Expression of Insulin-like Peptides from Neuroendocrine Cells in the CNS Contributes to Growth Regulation in Drosophila

Ikeya, T., Galic, M., Belawat, P., Nairz, K., & Hafen, E. (2002) · Current Biology · doi:10.1016/s0960-9822(02)01043-6 · Cited by 766

Ectopic and increased expression of fasciclin II alters motoneuron growth cone guidance

Lin, D. M., & Goodman, C. S. (1994) · Neuron · doi:10.1016/0896-6273(94)90022-1 · Cited by 674

Insulin/IGF and target of rapamycin signaling: a TOR de force in growth control

Oldham, S., & Hafen, E. (2003) · Trends in Cell Biology · doi:10.1016/s0962-8924(02)00042-9 · Cited by 552

Neuropeptides and Neuropeptide Receptors in the Drosophila melanogaster Genome

Hewes, R. S., & Taghert, P. H. (2001) · Genome Research · doi:10.1101/gr.169901 · Cited by 541

Natural Behavior Polymorphism Due to a cGMP-Dependent Protein Kinase of Drosophila

Osborne, K. A., Robichon, A., Burgess, E., Butland, S., Shaw, R. A., Coulthard, A., Pereira, H. S., Greenspan, R. J., & Sokolowski, M. B. (1997) · Science · doi:10.1126/science.277.5327.834 · Cited by 536

The Drosophila phosphoinositide 3-kinase Dp110 promotes cell growth.

Leevers, S. J., Weinkove, D., MacDougall, L. K., Hafen, E., & Waterfield, M. D. (1996) · The EMBO Journal · doi:10.1002/j.1460-2075.1996.tb01049.x · Cited by 487

Developmental Control of Foraging and Social Behavior by the Drosophila Neuropeptide Y-like System

Wu, Q., Wen, T., Lee, G., Park, J. H., Cai, H. N., & Shen, P. (2003) · Neuron · doi:10.1016/s0896-6273(03)00396-9 · Cited by 436

Evolution of neuropeptide Y, peptide YY and pancreatic polypeptide

Larhammar, D. (1996) · Regulatory Peptides · doi:10.1016/0167-0115(95)00169-7 · Cited by 389

Role of Dynamin in the Formation of Transport Vesicles from the Trans-Golgi Network

Jones, S. M., Howell, K. E., Henley, J. R., Cao, H., & McNiven, M. A. (1998) · Science · doi:10.1126/science.279.5350.573 · Cited by 318

Behavioral insensitivity to restraint stress, absent fear suppression of behavior and impaired spatial learning in transgenic rats with hippocampal neuropeptide Y overexpression

Thorsell, A., Michalkiewicz, M., Dumont, Y., Quirion, R., Caberlotto, L., Rimondini, R., Mathé, A. A., & Heilig, M. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.220232997 · Cited by 315

Behavioral characterization of neuropeptide Y knockout mice

Bannon, A. W., Seda, J., Carmouche, M., Francis, J. M., Norman, M. H., Karbon, B., & McCaleb, M. L. (2000) · Brain Research · doi:10.1016/s0006-8993(00)02285-x · Cited by 290

Drosophila PTEN Regulates Cell Growth and Proliferation through PI3K-Dependent and -Independent Pathways

Gao, X., Neufeld, T. P., & Pan, D. (2000) · Developmental Biology · doi:10.1006/dbio.2000.9680 · Cited by 260

Identification of a Drosophila brain-gut peptide related to the neuropeptide Y family

Brown, M. R., Crim, J. W., Arata, R. C., Cai, H. N., Chun, C., & Shen, P. (1999) · Peptides · doi:10.1016/s0196-9781(99)00097-2 · Cited by 256

Kinesin and dynamin are required for post-Golgi transport of a plasma-membrane protein

Kreitzer, G., Marmorstein, A., Okamoto, P., Vallee, R., & Rodriguez-Boulan, E. (2000) · Nature Cell Biology · doi:10.1038/35000081 · Cited by 242

Brain Insulin: Regulation, Mechanisms of Action and Functions

Gerozissis, K. (2003) · Cellular and Molecular Neurobiology · doi:10.1023/a:1022598900246 · Cited by 234

Postsynaptic PKA Controls Quantal Size and Reveals a Retrograde Signal that Regulates Presynaptic Transmitter Release in Drosophila

Davis, G. W., DiAntonio, A., Petersen, S. A., & Goodman, C. S. (1998) · Neuron · doi:10.1016/s0896-6273(00)80458-4 · Cited by 208

Neuronal overexpression of APPL, the Drosophila homologue of the amyloid precursor protein (APP), disrupts axonal transport

Torroja, L., Chu, H., Kotovsky, I., & White, K. (1999) · Current Biology · doi:10.1016/s0960-9822(99)80215-2 · Cited by 203

Drosophila neuropeptide F and its receptor, NPFR1, define a signaling pathway that acutely modulates alcohol sensitivity

Wen, T., Parrish, C. A., Xu, D., Wu, Q., & Shen, P. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0406814102 · Cited by 197

Characterization of a functional neuropeptide F receptor from Drosophila melanogaster

Garczynski, S. F., Brown, M. R., Shen, P., Murray, T. F., & Crim, J. W. (2002) · Peptides · doi:10.1016/s0196-9781(01)00647-7 · Cited by 166

Sugars and Fats: The Neurobiology of Preference

Levine, A. S., Kotz, C. M., & Gosnell, B. A. (2003) · Journal of Nutrition · doi:10.1093/jn/133.3.831s · Cited by 152

Axons Guided by Insulin Receptor in Drosophila Visual System

Song, J., Wu, L., Chen, Z., Kohanski, R. A., & Pick, L. (2003) · Science · doi:10.1126/science.1081203 · Cited by 148

Diverse functions of neuropeptide Y revealed using genetically modified animals

Thorsell, A., & Heilig, M. A. (2002) · Neuropeptides · doi:10.1054/npep.2002.0897 · Cited by 148

The S6 kinase Signaling Pathway In The Control of Development and Growth

Thomas, G. (2002) · Biological Research · doi:10.4067/s0716-97602002000200022 · Cited by 144

Regulation of protein synthesis by branched-chain amino acids

Kimball, S., & Jefferson, L. (2001) · Current opinion in clinical nutrition and metabolic care · doi:10.1097/00075197-200101000-00008 · Cited by 138

Disruption of Golgi structure and function in mammalian cells expressing a mutant dynamin

Cao, H., Krueger, E. W., & McNiven, M. A. (2000) · Journal of Cell Science · doi:10.1242/jcs.113.11.1993 · Cited by 138

Drosophila neuropeptide F mediates integration of chemosensory stimulation and conditioning of the nervous system by food

Shen, P., & Cai, H. N. (2001) · Journal of Neurobiology · doi:10.1002/neu.1012 · Cited by 131

Visualization of neuropeptide expression, transport, and exocytosis in Drosophila melanogaster

Rao, S., Lang, C., Levitan, E. S., & Deitcher, D. L. (2001) · Journal of Neurobiology · doi:10.1002/neu.1072 · Cited by 130

Neurobiology of Food and Fluid Intake

(1990) · Handbook of behavioral neurobiology · doi:10.1007/978-1-4613-0577-4 · Cited by 128

Recent advances in our understanding of risk-sensitive foraging preferences

Melissa Bateson, B. (2002) · Proceedings of The Nutrition Society · doi:10.1079/pns2002181 · Cited by 120

Efficient and heritable functional knock-out of an adult phenotype in Drosophila using a GAL4-driven hairpin RNA incorporating a heterologous spacer

Piccin, A., Salameh, A., Benna, C., Sandrelli, F., Mazzotta, G., Zordan, M., Rosato, E., Kyriacou, C. P., & Costa, R. (2001) · Nucleic Acids Research · doi:10.1093/nar/29.12.e55 · Cited by 105

NPY ablation in C57BL/6 mice leads to mild obesity and to an impaired refeeding response to fasting

Segal‐Lieberman, G., Trombly, D. J., Juthani, V. V., Wang, X., & Maratos–Flier, E. (2003) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00491.2002 · Cited by 81

Altering Drosophila S6 kinase activity is consistent with a role for S6 kinase in growth

Barcelo, H., & Stewart, M. J. (2002) · Genesis · doi:10.1002/gene.10132 · Cited by 78

TARGETED EXPRESSION OF TEMPERATURE-SENSITIVE DYNAMIN TO STUDY NEURAL MECHANISMS OF COMPLEX BEHAVIOR IN Drosophila

Kitamoto, T. (2002) · Journal of Neurogenetics · doi:10.1080/01677060216295 · Cited by 66

Our journey with neuropeptide Y: effects on ingestive behaviors and energy expenditure

Levine, A. S., Jewett, D. C., Cleary, J. P., Kotz, C. M., & Billington, C. J. (2004) · Peptides · doi:10.1016/j.peptides.2004.01.005 · Cited by 50

Neuropeptide Y differentiates between exocytotic and nonexocytotic noradrenaline release in guinea-pig heart

Haass, M., Hock, M., Richardt, G., & Sch�mig, A. (1989) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/bf00260605 · Cited by 34

Controlling how many cells make a fly.

Moore, P. (2003) · Journal of Biology · doi:10.1186/1475-4924-2-16 · Cited by 4

The many faces of insulin-like peptide signalling in the brain

Fernandez, A. M., & Torres-Alemán, I. (2012) · Nature reviews. Neuroscience · doi:10.1038/nrn3209 · Cited by 872

A Neural Circuit Mechanism Integrating Motivational State with Memory Expression in Drosophila

Krashes, M. J., DasGupta, S., Vreede, A., White, B., Armstrong, J. D., & Waddell, S. (2009) · Cell · doi:10.1016/j.cell.2009.08.035 · Cited by 598

Presynaptic facilitation by neuropeptide signaling mediates odor-driven food search

Root, C. M., Ko, K. I., Jafari, A., & Wang, J. W. (2011) · Cell · doi:10.1016/j.cell.2011.02.008 · Cited by 526

Drosophila neuropeptides in regulation of physiology and behavior

Nässel, D. R., & Winther, Å. M. E. (2010) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2010.04.010 · Cited by 493

The Digestive Tract of Drosophila melanogaster

Lemaitre, B., & Miguel-Aliaga, I. (2013) · Annual Review of Genetics · doi:10.1146/annurev-genet-111212-133343 · Cited by 469