The many faces of insulin-like peptide signalling in the brain

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Central nervous system control of food intake and body weight

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Role of Brain Insulin Receptor in Control of Body Weight and Reproduction

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New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory?

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Cellular Actions of the Insulin-Like Growth Factor Binding Proteins

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The self-tuning neuron: synaptic scaling of excitatory synapses

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Cell death and control of cell survival in the oligodendrocyte lineage

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Intranasal Insulin Therapy for Alzheimer Disease and Amnestic Mild Cognitive Impairment: A Pilot Clinical Trial

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The Insulin-Like Growth Factor-Binding Protein (IGFBP) Superfamily

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Circulating Insulin-Like Growth Factor I Mediates Exercise-Induced Increases in the Number of New Neurons in the Adult Hippocampus

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Intranasal insulin improves cognition and modulates β-amyloid in early AD

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Circulating Insulin-Like Growth Factor I Mediates Effects of Exercise on the Brain

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Molecular Evolution and Functional Characterization of Drosophila Insulin-Like Peptides

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The cerebrospinal fluid provides a proliferative niche for neural progenitor cells

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Depression: a case of neuronal life and death?

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Critical periods for experience-dependent synaptic scaling in visual cortex

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Recruitment of functional GABAA receptors to postsynaptic domains by insulin

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Brain Insulin Receptors and Spatial Memory

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Irs-2 coordinates Igf-1 receptor-mediated β-cell development and peripheral insulin signalling

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Presynaptic facilitation by neuropeptide signaling mediates odor-driven food search

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Insulin/Insulin-like Growth Factor I Hybrid Receptors Have Different Biological Characteristics Depending on the Insulin Receptor Isoform Involved

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The source of cerebral insulin

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Saturable transport of insulin from plasma into the central nervous system of dogs in vivo. A mechanism for regulated insulin delivery to the brain.

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Expression of Cerebellar Long-Term Depression Requires Postsynaptic Clathrin-Mediated Endocytosis

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The Insulin-Like Growth Factor System and Its Pleiotropic Functions in Brain

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Localization of insulin receptor mRNA in rat brain by in situ hybridization

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Serum insulin-like growth factor I regulates brain amyloid-β levels

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The role of the insulin-like growth factors in the central nervous system

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Serum insulin-like growth factor I regulates brain amyloid-β levels

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Insulin receptor signaling regulates synapse number, dendritic plasticity, and circuit function in vivo

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Fat cells reactivate quiescent neuroblasts via TOR and glial insulin relays in Drosophila

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Aspects of growth hormone and insulin-like growth factor-I related to neuroprotection, regeneration, and functional plasticity in the adult brain

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Insulin-like growth factor I is required for vessel remodeling in the adult brain.

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Cellular pattern of type-I insulin-like growth factor receptor gene expression during maturation of the rat brain: Comparison with insulin-like growth factors I and II

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Expression of Somatomedin/Insulin-Like Growth Factor Messenger Ribonucleic Acids in the Human Fetus: Identification, Characterization, and Tissue Distribution*

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Functional inactivation of the IGF-I and insulin receptors in skeletal muscle causes type 2 diabetes

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Insulin-Like Growth Factor-I Promotes Neurogenesis and Synaptogenesis in the Hippocampal Dentate Gyrus during Postnatal Development

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A Drosophila Insulin-like Peptide Promotes Growth during Nonfeeding States

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Identification of a family of low-affinity insulin-like growth factor binding proteins (IGFBPs): Characterization of connective tissue growth factor as a member of the IGFBP superfamily

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IGF-I specifically enhances axon outgrowth of corticospinal motor neurons

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Acute and gradual increases in BDNF concentration elicit distinct signaling and functions in neurons

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Neuronal Activity Drives Localized Blood-Brain-Barrier Transport of Serum Insulin-like Growth Factor-I into the CNS

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Insulin gene expression and insulin synthesis in mammalian neuronal cells.

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Epigenetic choreographers of neurogenesis in the adult mammalian brain

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The insulin receptor tyrosine kinase substrate p58/53 and the insulin receptor are components of CNS synapses

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Direct Control of Germline Stem Cell Division and Cyst Growth by Neural Insulin in Drosophila

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Cellular Pattern of Insulin-Like Growth Factor-I (IGF-I) and Type I IGF Receptor Gene Expression in Early Organogenesis: Comparison with IGF-II Gene Expression

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Insulin-like growth factor-I and neurogenesis in the adult mammalian brain

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The insulin paradox: aging, proteotoxicity and neurodegeneration

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Insulin promotes rapid delivery of N -methyl- d - aspartate receptors to the cell surface by exocytosis

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Tyrosine phosphorylation of GluR2 is required for insulin-stimulated AMPA receptor endocytosis and LTD

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Brain IGF-1 Receptors Control Mammalian Growth and Lifespan through a Neuroendocrine Mechanism

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The effects of exercise on spatial learning and anxiety-like behavior are mediated by an IGF-I-dependent mechanism related to hippocampal neurogenesis

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Transient IGF-I gene expression during the maturation of functionally related central projection neurons

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Regulation of aversion to noxious food by Drosophila neuropeptide Y– and insulin-like systems

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The role of insulin and insulin-like growth factor I in the molecular and cellular mechanisms underlying the pathology of Alzheimer's disease

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Expression of the insulin-like growth factor II gene in the choroid plexus and the leptomeninges of the adult rat central nervous system.

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Frequency-modulated 50 kHz ultrasonic vocalizations: a tool for uncovering the molecular substrates of positive affect

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Imp-L2, a putative homolog of vertebrate IGF-binding protein 7, counteracts insulin signaling in Drosophila and is essential for starvation resistance

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Fibroblast growth factor-mediated proliferation of central nervous system precursors depends on endogenous production of insulin-like growth factor I.

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SUMOylation Mediates the Nuclear Translocation and Signaling of the IGF-1 Receptor

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Awake Intranasal Insulin Delivery Modifies Protein Complexes and Alters Memory, Anxiety, and Olfactory Behaviors

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Neural and Head Induction by Insulin-like Growth Factor Signals

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Insulin promotes dendritic spine and synapse formation by the PI3K/Akt/mTOR and Rac1 signaling pathways

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Choroid Plexus Megalin Is Involved in Neuroprotection by Serum Insulin-Like Growth Factor I

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Central actions of liver-derived insulin-like growth factor I underlying its pro-cognitive effects

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Insulin-like growth factor 1 regulates developing brain glucose metabolism

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Insulin-like growth factor-1 and post-ischemic brain injury

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Cognitive changes during growth hormone replacement in adult men

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Co-ordinated and cellular specific induction of the components of the IGF/IGFBP axis in the rat brain following hypoxic–ischemic injury

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Kinetics and specificity of insulin uptake from plasma into cerebrospinal fluid.

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Diabetes and Insulin in Regulation of Brain Cholesterol Metabolism

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Therapeutic actions of insulin-like growth factor I on APP/PS2 mice with severe brain amyloidosis

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Insulin Is Released from Rat Brain Neuronal Cells in Culture

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Binding and Internalization of Insulin and Insulin-Like Growth Factors by Isolated Brain Microvessels

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Insulin-like receptor and insulin-like peptide are localized at neuromuscular junctions in Drosophila

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Megalin is an endocytic receptor for insulin.

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IGF-1 Modulates N and L Calcium Channels in a PI 3-Kinase-Dependent Manner

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Exercise, Learned Helplessness, and the Stress-Resistant Brain

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Axons Guided by Insulin Receptor in Drosophila Visual System

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