SYD-2 Liprin-α organizes presynaptic active zone formation through ELKS

Dai, Ya, Taru, Hidenori, Deken, Scott L, Grill, Brock, Ackley, Brian, Nonet, Michael L, Jin, Yishi·2006·Nature Neuroscience

Cited by (212)

Items 101–200 of 212

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  15. The Scaffolding Protein SYD-2/Liprin-α Regulates the Mobility and Polarized Distribution of Dense-Core Vesicles in C. elegans Motor Neurons
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  16. Intracellular protein complexes involved in synapse assembly in presynaptic neurons
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  17. Dynamic mechanisms of neuroligin-dependent presynaptic terminal assembly in living cortical neurons
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  19. Structural insights into selective interaction between type IIa receptor protein tyrosine phosphatases and Liprin-α
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  21. The role of RIM1α in BDNF-enhanced glutamate release
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  22. Involvement of ELKS, an active zone protein, in exocytotic release from RBL-2H3 cells
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  30. Unraveling the mechanisms of synapse formation and axon regeneration: the awesome power of C. elegans genetics
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  59. Molecular Composition of Developing Glutamatergic Synapses
    Stephanie L. Barrow, A. Kimberley McAllister · 2013 · Elsevier eBooks
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    Jan Krajniak, Hang Lu · 2010
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    Jiaxing Li · 2017 · Deep Blue (University of Michigan)
  93. Pre- and Postsynaptic Assembly and Maturation
    Stephan J. Sigrist, Carolin Wichmann · 2013 · Elsevier eBooks
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    Tahere Kalantary Dehaghi · 2019
  95. Presynaptic Mechanisms for Cargo Recruitment
    Hajnalka Nyitrai · 2019 · Digital Access to Scholarship at Harvard (DASH) (Harvard University)
  96. Liprins, ELKS, and RIM-BP Proteins
    Susanne Schoch, Johannes Alexander Müller, Eva M. Schönhense, Julia Betzin · 2015 · Elsevier eBooks
  97. Active Zone☆
    M.Y. Wong, Pascal S. Kaeser · 2014 · Elsevier eBooks
  98. Quantitative molecular physiology at active zones of calyceal synapses of the auditory pathway
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  99. Characterization of factors affecting synaptic transmission in C. elegans
    Barbara Jánosi · 2023
  100. Author Response: Molecular and organizational diversity intersect to generate functional synaptic heterogeneity within and between excitatory neuronal subtypes
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