The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Drosophila spichthyin inhibits BMP signaling and regulates synaptic growth and axonal microtubules
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“a number of HSP proteins are inhibitors of BMP signalling in model organisms or in cultured cells”
In the citing paper
“upregulated BMP signalling has been proposed as a unifying pathogenic mechanism for HSP [34–36].”
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
NIPA1 gene mutations cause autosomal dominant hereditary spastic paraplegia (SPG6)
Rainier, S., Chai, J.-H., Tokarz, D., Nicholls, R. D., & Fink, J. K. (2003) · The American Journal of Human Genetics · doi:10.1086/378817 · Cited by 207
Chen, S., Song, C., Guo, H., Xu, P., Huang, W., Zhou, Y., Sun, J., Li, C., Du, Y., Li, X., et al. (2005) · Human Mutation · doi:10.1002/humu.20126 · Cited by 61
Research works printed but not linked: 48
- Stokin, G.B. & Goldstein, L.S.B. Axonal transport and Alzheimer's disease. Annu. Rev. Biochem. 75, 607–627 (2006). · DOI · Paper page
- Reid, E. Science in motion: common molecular pathological themes emerge in the hereditary spastic paraplegias. J. Med. Genet. 40, 81–86 (2003). · DOI
- Fink, J.K. Hereditary spastic paraplegia. Curr. Neurol. Neurosci. Rep. 6, 65–76 (2006). · DOI · Paper page
- Zeitlmann, L., Sirim, P., Kremmer, E. & Kolanus, W. Cloning of ACP33 as a novel intracellular ligand of CD4. J. Biol. Chem. 276, 9123–9132 (2001). · DOI
- Simpson, M.A. et al. Maspardin is mutated in mast syndrome, a complicated form of hereditary spastic paraplegia associated with dementia. Am. J. Hum. Genet. 73, 1147–1156 (2003). · DOI
- Bakowska, J.C., Jenkins, R., Pendleton, J. & Blackstone, C. The Troyer syndrome (SPG20) protein spartin interacts with Eps15. Biochem. Biophys. Res. Commun. 334, 1042–1048 (2005). · DOI
- Reid, E. et al. The hereditary spastic paraplegia protein spastin interacts with the ESCRT-III complex-associated endosomal protein CHMP1B. Hum. Mol. Genet. 14, 19–38 (2005). · DOI
- Mannan, A.U. et al. ZFYVE27 (SPG33), a novel spastin-binding protein, is mutated in hereditary spastic paraplegia. Am. J. Hum. Genet. 79, 351–357 (2006). · DOI
- Otomo, A. et al. ALS2, a novel guanine nucleotide exchange factor for the small GTPase Rab5, is implicated in endosomal dynamics. Hum. Mol. Genet. 12, 1671–1687 (2003). · DOI
- Reed, J.A. et al. A novel NIPA1 mutation associated with a pure form of autosomal dominant hereditary spastic paraplegia. Neurogenetics 6, 79–84 (2005). · DOI
- Kaneko, S. et al. Novel SPG6 mutation p.A100T in a Japanese family with autosomal dominant form of hereditary spastic paraplegia. Mov. Disord. 21, 1531–1533 (2006). · DOI
- Chai, J.H. et al. Identification of four highly conserved genes between breakpoint hotspots BP1 and BP2 of the Prader-Willi/Angelman Syndromes deletion region that have undergone evolutionary transposition mediated by flanking duplicons. Am. J. Hum. Genet. 73, 898–925 (2003). · DOI · Paper page
- Lefèvre, C. et al. Mutations in ichthyin a new gene on chromosome 5q33 in a new form of autosomal recessive congenital ichthyosis. Hum. Mol. Genet. 13, 2473–2482 (2004). · DOI
- DiGiovanna, J.J. & Robinson-Bostom, L. Ichthyosis: etiology, diagnosis, and management. Am. J. Clin. Dermatol. 4, 81–95 (2003). · DOI
- Aberle, H. et al. Wishful thinking encodes a BMP type II receptor that regulates synaptic growth in Drosophila. Neuron 33, 545–558 (2002). · DOI
- Marqués, G. et al. The Drosophila BMP type II receptor Wishful Thinking regulates neuromuscular synapse morphology and function. Neuron 33, 529–543 (2002). · DOI · Paper page
- McCabe, B.D. et al. The BMP homolog Gbb provides a retrograde signal that regulates synaptic growth at the Drosophila neuromuscular junction. Neuron 39, 241–254 (2003). · DOI · Paper page
- McCabe, B.D. et al. Highwire regulates presynaptic BMP signaling essential for synaptic growth. Neuron 41, 891–905 (2004). · DOI
- Eaton, B.A. & Davis, G.W. LIM Kinase1 controls synaptic stability downstream of the type II BMP receptor. Neuron 47, 695–708 (2005). · DOI
- Sweeney, S.T. & Davis, G.W. Unrestricted synaptic growth in spinster—a late endosomal protein implicated in TGF-β-mediated synaptic growth regulation. Neuron 36, 403–416 (2002). · DOI
- Wan, H.I. et al. Highwire regulates synaptic growth in Drosophila. Neuron 26, 313–329 (2000). · DOI · Paper page
- Collins, C.A., Wairkar, Y.P., Johnson, S.L. & DiAntonio, A. Highwire restrains synaptic growth by attenuating a MAP kinase signal. Neuron 51, 57–69 (2006). · DOI · Paper page
- Sherwood, N.T., Sun, Q., Xue, M., Zhang, B. & Zinn, K. Drosophila spastin regulates synaptic microtubule networks and is required for normal motor function. PLoS Biol. 2, e429 (2004). · DOI · Paper page
- Trotta, N., Orso, G., Rossetto, M.G., Daga, A. & Broadie, K. The hereditary spastic paraplegia gene, spastin, regulates microtubule stability to modulate synaptic structure and function. Curr. Biol. 14, 1135–1147 (2004). · DOI · Paper page
- Webster, D.R. & Borisy, G.G. Microtubules are acetylated in domains that turn over slowly. J. Cell Sci. 92, 57–65 (1989). · DOI · Paper page
- Vadlamudi, R.K. et al. p21-activated kinase 1 regulates microtubule dynamics by phosphorylating tubulin cofactor B. Mol. Cell. Biol. 25, 3726–3736 (2005). · DOI
- Roos, J., Hummel, T., Ng, N., Klambt, C. & Davis, G.W. Drosophila Futsch regulates synaptic microtubule organization and is necessary for synaptic growth. Neuron 26, 371–382 (2000). · DOI · Paper page
- Goold, R.G., Owen, R. & Gordon-Weeks, P.R. Glycogen synthase kinase 3β phosphorylation of microtubule-associated protein 1B regulates the stability of microtubules in growth cones. J. Cell Sci. 112, 3373–3384 (1999). · DOI
- O'Connor, M.B., Umulis, D., Othmer, H. & Blair, S.S. Shaping BMP morphogen gradients in the Drosophila embryo and pupal wings. Development 133, 183–193 (2006). · DOI · Paper page
- Ralston, A. & Blair, S.S. Long-range Dpp signaling is regulated to restrict BMP signaling to a crossvein competent zone. Dev. Biol. 280, 187–200 (2005). · DOI
- Dudu, V. et al. Postsynaptic Mad signaling at the Drosophila neuromuscular junction. Curr. Biol. 16, 625–635 (2006). · DOI
- Jékely, G. & Rørth, P. Hrs mediates downregulation of multiple signalling receptors in Drosophila. EMBO Rep. 4, 1163–1168 (2003). · DOI
- Thompson, B.J. et al. Tumor suppressor properties of the ESCRT-II complex component Vps25 in Drosophila. Dev. Cell 9, 711–720 (2005). · DOI · Paper page
- Lu, H. & Bilder, D. Endocytic control of epithelial polarity and proliferation in Drosophila. Nat. Cell Biol. 7, 1232–1242 (2005). · DOI · Paper page
- Eaton, B.A., Fetter, R.D. & Davis, G.W. Dynactin is necessary for synapse stabilization. Neuron 34, 729–741 (2002). · DOI
- Gibson, M.C. & Perrimon, N. Extrusion and death of DPP/BMP-compromised epithelial cells in the developing Drosophila wing. Science 307, 1785–1789 (2005). · DOI
- Li, A.G., Wang, D., Feng, X.-H. & Wang,, X.-J. Latent TGFβ1 overexpression in keratinocytes results in a severe psoriasis-like skin disorder. EMBO J. 23, 1770–1781 (2004). · DOI
- Casso, D., Ramirez-Weber, F.A. & Kornberg, T.B. GFP-tagged balancer chromosomes for Drosophila melanogaster. Mech. Dev. 91, 451–454 (2000). · DOI
- Brand, A.H. & Perrimon, N. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118, 401–415 (1993). · DOI · Paper page
- Brummel, T. et al. The Drosophila Activin receptor Baboon signals through dSmad2 and controls cell proliferation but not patterning during larval development. Genes Dev. 13, 98–111 (1999). · DOI
- Littleton, J.T., Bellen, H.J. & Perin, M.S. Expression of synaptotagmin in Drosophila reveals transport and localization of synaptic vesicles to the synapse. Development 118, 1077–1088 (1993). · DOI
- Persson, U. et al. The L45 loop in type I receptors for TGF-β family members is a critical determinant in specifying Smad isoform activation. FEBS Lett. 434, 83–87 (1998). · DOI · Paper page
- Stewart, B.A., Atwood, H.L., Renger, J.J., Wang, J. & Wu, C.-F. Improved stability of Drosophila larval neuromuscular preparations in haemolymph-like physiological solutions. J. Comp. Physiol. [A] 175, 179–191 (1994). · DOI · Paper page
- Wucherpfennig, T., Wilsch-Brauninger, M. & Gonzalez-Gaitan,, M. Role of Drosophila Rab5 during endosomal trafficking at the synapse and evoked neurotransmitter release. J. Cell Biol. 161, 609–624 (2003). · DOI · Paper page
- Krämer, H. & Phistry, M. Mutations in the Drosophila hook gene inhibit endocytosis of the boss transmembrane ligand into multivesicular bodies. J. Cell Biol. 133, 1205–1215 (1996). · DOI
- Parnas, D., Haghighi, A.P., Fetter, R.D., Kim, S.W. & Goodman, C.S. Regulation of postsynaptic structure and protein localization by the Rho-type guanine nucleotide exchange factor dPix. Neuron 32, 415–424 (2001). · DOI · Paper page
- Zinsmaier, K.E. et al. A cysteine-string protein is expressed in retina and brain of Drosophila. J. Neurogenet. 7, 15–29 (1990). · DOI
- Chenna, R. et al. Multiple sequence alignment with the Clustal series of programs. Nucleic Acids Res. 31, 3497–3500 (2003). · DOI · Paper page
Cited by
Hereditary spastic paraplegia: clinical features and pathogenetic mechanisms
Salinas, S., Proukakis, C., Crosby, A., & Warner, T. T. (2008) · The Lancet Neurology · doi:10.1016/s1474-4422(08)70258-8 · Cited by 474
van der Zwaag, B., Staal, W. G., Hochstenbach, R., Poot, M., Spierenburg, H. A., de Jonge, M. V., Verbeek, N. E., van 't Slot, R., van Es, M. A., Staal, F. J., et al. (2010) · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics · doi:10.1002/ajmg.b.31055 · Cited by 108
Writing Committee for the ENIGMA-CNV Working Group, van der Meer, D., Sønderby, I. E., Kaufmann, T., Walters, G. B., Abdellaoui, A., Ames, D., Amunts, K., Andersson, M., Armstrong, N. J., et al. (2020) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2019.3779 · Cited by 87
Korolchuk, V. I., Schütz, M. M., Gómez-Llorente, C., Rocha, J., Lansu, N. R., Collins, S. M., Wairkar, Y. P., Robinson, I. M., & O'Kane, C. J. (2007) · Journal of Cell Science · doi:10.1242/jcs.012336 · Cited by 86
Self-citationKim, S., Wairkar, Y. P., Daniels, R. W., & DiAntonio, A. (2010) · Journal of Cell Biology · doi:10.1083/jcb.200911126 · Cited by 82
Metadata
- Authors
- Wang, X., Shaw, W. R., Tsang, H. T. H., Reid, E., & O'Kane, C. J.
- Venue
- Nature Neuroscience
- Published
- 2007-01-14
- Volume
- 10
- Issue
- 2
- Pages
- 177-185
- ISSN
- 1097-6256
- 1546-1726
- Cited by
- 162
- References
- 2
- Language
- en
- Licence
- www.springer.com/tdm (tdm)
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Drosophila spichthyin inhibits BMP signaling and regulates synaptic growth and axonal microtubules. https://app.cochat.ai/papers/10.1038/nn1841
- The paper
- Wang, X., Shaw, W. R., Tsang, H. T. H., Reid, E., & O'Kane, C. J. (2007). Drosophila spichthyin inhibits BMP signaling and regulates synaptic growth and axonal microtubules. Nature Neuroscience. https://doi.org/10.1038/nn1841
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.