The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
The emerging field of RNA nanotechnology
Open accessAbstract
RNA can be designed and manipulated just like DNA while having different rules for base-pairing and displaying functions similar to proteins. The large variety of loops and motifs in RNA allow them to fold into numerous complicated structures. This diversity provides a platform for identifying viable building blocks for particle assemblies, substrate binding and manufacture engineering. RNA thermal stability allows production of multivalent nanostructures with defined stoichiometry. Here we review the unique qualities of RNA nanotechnology and their distinct properties inside the body. We describe techniques for constructing RNA nanoparticles from different building blocks and their applications in nanomedicine. Finally, we discuss challenges in predicting and synthesizing RNA and offer some perspectives on the yield and cost of RNA production.
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Cites
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“Among the three helices (RNA/RNA, RNA/DNA and DNA/DNA), the RNA/RNA double helix is the most stabl”
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Diverse Applications of Nanomedicine
Pelaz, B., Alexiou, C., Alvarez-Puebla, R. A., Alves, F., Andrews, A. M., Ashraf, S., Balogh, L. P., Ballerini, L., Bestetti, A., Brendel, C., et al. (2017) · ACS Nano · doi:10.1021/acsnano.6b06040 · Cited by 1,350
Challenges and opportunities for structural DNA nanotechnology
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Functional and Biomimetic Materials for Engineering of the Three-Dimensional Cell Microenvironment
Huang, G., Li, F., Zhao, X., Ma, Y., Li, Y., Lin, M., Jin, G., Lu, T. J., Genin, G. M., & Xu, F. (2017) · Chemical Reviews · doi:10.1021/acs.chemrev.7b00094 · Cited by 825
Exosomes are natural carriers of exogenous siRNA to human cells in vitro
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Shu, D., Shu, Y., Haque, F., Abdelmawla, S., & Guo, P. (2011) · Nature Nanotechnology · doi:10.1038/nnano.2011.105 · Cited by 435
Self-citation
Metadata
- Authors
- Guo, P.
- Venue
- Nature Nanotechnology
- Published
- 2010-11-21
- Volume
- 5
- Issue
- 12
- Pages
- 833-842
- ISSN
- 1748-3387 (ISSN-L)
- 1748-3395
- OpenAlex
- W2164530723
- Cited by
- 718
- References
- 6
- FWCI
- 17.13
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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